Oxidative stress and liver toxicity in rats and human hepatoma cell line induced by pentachlorophenol and its major metabolite tetrachlorohydroquinone

Toxicology Letters

Volumn 122, Issue 2, 2001, Pages 157-169

  Wang, Ying Jan ^a   Lee, Ching Chang ^a   Chang, Wen Ching ^a   Liou, Hung Bin ^a   Ho, Yuan Soon ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cell death mechanisms; Gene expressions; Lipid peroxidation; Liver injury; Pentachlorophenol; Tetrachlorohydroquinone

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL; ASPARTATE AMINOTRANSFERASE; HEAT SHOCK PROTEIN 70; PENTACHLOROPHENOL; PESTICIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TETRACHLOROHYDROQUINONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER TOXICITY; MALE; METABOLITE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN URINE LEVEL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SIGNAL TRANSDUCTION; VITAMIN SUPPLEMENTATION;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; DINOPROST; F2-ISOPROSTANES; HUMANS; HYDROQUINONES; LIVER; MALE; OXIDATIVE STRESS; PENTACHLOROPHENOL; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; TUMOR CELLS, CULTURED; VITAMIN E;

EID: 0035919072     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(01)00361-7     Document Type: Article

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