메뉴 건너뛰기




Volumn 66, Issue 3, 2006, Pages 1824-1832

Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROLACTIN; RECOMBINANT PROTEIN; SMAD PROTEIN; STAT5A PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 32944469616     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-2292     Document Type: Article
Times cited : (101)

References (62)
  • 1
    • 0019188943 scopus 로고
    • Ontogeny and evolution of prolactin's functions
    • Nicoll CS. Ontogeny and evolution of prolactin's functions. Fed Proc 1980;39:2563-6.
    • (1980) Fed Proc , vol.39 , pp. 2563-2566
    • Nicoll, C.S.1
  • 2
    • 0041306993 scopus 로고    scopus 로고
    • Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice
    • Ormandy CJ, Naylor M, Harris J, et al. Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice. Recent Prog Horm Res 2003;58:297-323.
    • (2003) Recent Prog Horm Res , vol.58 , pp. 297-323
    • Ormandy, C.J.1    Naylor, M.2    Harris, J.3
  • 3
    • 0032460226 scopus 로고    scopus 로고
    • Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice
    • Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 1998;19:225-68.
    • (1998) Endocr Rev , vol.19 , pp. 225-268
    • Bole-Feysot, C.1    Goffin, V.2    Edery, M.3    Binart, N.4    Kelly, P.A.5
  • 4
    • 0030670222 scopus 로고    scopus 로고
    • Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene
    • Horseman ND, Zhao W, Montecino-Rodriguez E, et al. Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene. EMBO J 1997;16:6926-35.
    • (1997) EMBO J , vol.16 , pp. 6926-6935
    • Horseman, N.D.1    Zhao, W.2    Montecino-Rodriguez, E.3
  • 5
    • 8544242334 scopus 로고    scopus 로고
    • Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse
    • Ormandy CJ, Camus A, Barra J, et al. Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev 1997;11:167-78.
    • (1997) Genes Dev , vol.11 , pp. 167-178
    • Ormandy, C.J.1    Camus, A.2    Barra, J.3
  • 6
    • 2942587457 scopus 로고    scopus 로고
    • Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice
    • Wagner KU, Krempler A, Triplett AA, et al. Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice. Mol Cell Biol 2004;24:5510-20.
    • (2004) Mol Cell Biol , vol.24 , pp. 5510-5520
    • Wagner, K.U.1    Krempler, A.2    Triplett, A.A.3
  • 10
    • 0031851198 scopus 로고    scopus 로고
    • Prolactin: The forgotten hormone of human breast cancer
    • Vonderhaar BK. Prolactin: the forgotten hormone of human breast cancer. Pharmacol Ther 1998;79:169-78.
    • (1998) Pharmacol Ther , vol.79 , pp. 169-178
    • Vonderhaar, B.K.1
  • 11
    • 0029005357 scopus 로고
    • Prolactin synthesis and secretion by human breast cancer cells
    • Ginsburg E, Vonderhaar BK. Prolactin synthesis and secretion by human breast cancer cells. Cancer Res 1995;55:2591-5.
    • (1995) Cancer Res , vol.55 , pp. 2591-2595
    • Ginsburg, E.1    Vonderhaar, B.K.2
  • 12
    • 0028963516 scopus 로고
    • Expression of prolactin and prolactin receptor in human breast carcinoma. Evidence for an autocrine/paracrine loop
    • Clevenger CV, Chang WP, Ngo W, Pasha TL, Montone KT, Tomaszewski JE. Expression of prolactin and prolactin receptor in human breast carcinoma. Evidence for an autocrine/paracrine loop. Am J Pathol 1995;146:695-705.
    • (1995) Am J Pathol , vol.146 , pp. 695-705
    • Clevenger, C.V.1    Chang, W.P.2    Ngo, W.3    Pasha, T.L.4    Montone, K.T.5    Tomaszewski, J.E.6
  • 13
    • 15444353990 scopus 로고    scopus 로고
    • Increased expression of prolactin receptor gene assessed by quantitative polymerase chain reaction in human breast tumors versus normal breast tissues
    • Touraine P, Martini JF, Zafrani B, et al. Increased expression of prolactin receptor gene assessed by quantitative polymerase chain reaction in human breast tumors versus normal breast tissues. J Clin Endocrinol Metab 1998;83:667-74.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 667-674
    • Touraine, P.1    Martini, J.F.2    Zafrani, B.3
  • 14
    • 0032758264 scopus 로고    scopus 로고
    • A human prolactin antagonist, hPRL-G129R, inhibits breast cancer cell proliferation through induction of apoptosis
    • Chen WY, Ramamoorthy P, Chen N, Sticca R, Wagner TE. A human prolactin antagonist, hPRL-G129R, inhibits breast cancer cell proliferation through induction of apoptosis [In Process Citation]. Clin Cancer Res 1999;5:3583-93.
    • (1999) Clin Cancer Res , vol.5 , pp. 3583-3593
    • Chen, W.Y.1    Ramamoorthy, P.2    Chen, N.3    Sticca, R.4    Wagner, T.E.5
  • 15
    • 0036550062 scopus 로고    scopus 로고
    • In vivo studies of the anti-tumor effects of a human prolactin antagonist, hPRL-G129R
    • Chen NY, Holle L, Li W, Peirce SK, Beck MT, Chen WY. In vivo studies of the anti-tumor effects of a human prolactin antagonist, hPRL-G129R Int J Oncol 2002;20:813-8.
    • (2002) Int J Oncol , vol.20 , pp. 813-818
    • Chen, N.Y.1    Holle, L.2    Li, W.3    Peirce, S.K.4    Beck, M.T.5    Chen, W.Y.6
  • 16
    • 0345257112 scopus 로고    scopus 로고
    • Inhibition of prolactin (PRL)-induced proliferative signals in breast cancer cells by a molecular mimic of phosphorylated PRL, S179D-PRL
    • Schroeder MD, Brockman JL, Walker AM, Schuler LA. Inhibition of prolactin (PRL)-induced proliferative signals in breast cancer cells by a molecular mimic of phosphorylated PRL, S179D-PRL. Endocrinology 2003;144:5300-7.
    • (2003) Endocrinology , vol.144 , pp. 5300-5307
    • Schroeder, M.D.1    Brockman, J.L.2    Walker, A.M.3    Schuler, L.A.4
  • 17
    • 0029012232 scopus 로고
    • Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines
    • Fuh G, Wells JA. Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines. J Biol Chem 1995;270:13133-7.
    • (1995) J Biol Chem , vol.270 , pp. 13133-13137
    • Fuh, G.1    Wells, J.A.2
  • 19
    • 0034696342 scopus 로고    scopus 로고
    • Prolactin gene-disruption arrests mammary gland development and retards T-antigen-induced tumor growth
    • Vomachka AJ, Pratt SL, Lockefeer JA, Horseman ND. Prolactin gene-disruption arrests mammary gland development and retards T-antigen-induced tumor growth. Oncogene 2000;19:1077-84.
    • (2000) Oncogene , vol.19 , pp. 1077-1084
    • Vomachka, A.J.1    Pratt, S.L.2    Lockefeer, J.A.3    Horseman, N.D.4
  • 20
    • 0037379779 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular aspects of cancer invasion
    • Mareel M, Leroy A. Clinical, cellular, and molecular aspects of cancer invasion. Physiol Rev 2003;83:337-76.
    • (2003) Physiol Rev , vol.83 , pp. 337-376
    • Mareel, M.1    Leroy, A.2
  • 21
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • Grunert S, Jechlinger M, Beug H. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat Rev Mol Cell Biol 2003;4:657-65.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 657-665
    • Grunert, S.1    Jechlinger, M.2    Beug, H.3
  • 22
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002;2:442-54.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 23
    • 0037148532 scopus 로고    scopus 로고
    • Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways
    • Janda E, Lehmann K, Killisch I, et al. Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J Cell Biol 2002;156:299-313.
    • (2002) J Cell Biol , vol.156 , pp. 299-313
    • Janda, E.1    Lehmann, K.2    Killisch, I.3
  • 24
    • 0242285692 scopus 로고    scopus 로고
    • TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression
    • Tang B, Vu M, Booker T, et al. TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression. J Clin Invest 2003;112:1116-24.
    • (2003) J Clin Invest , vol.112 , pp. 1116-1124
    • Tang, B.1    Vu, M.2    Booker, T.3
  • 25
    • 0037816160 scopus 로고    scopus 로고
    • Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis
    • Siegel PM, Shu W, Cardiff RD, Muller WJ, Massague J. Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis. Proc Natl Acad Sci U S A 2003;100:8430-5.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8430-8435
    • Siegel, P.M.1    Shu, W.2    Cardiff, R.D.3    Muller, W.J.4    Massague, J.5
  • 26
    • 0242552529 scopus 로고    scopus 로고
    • Increased malignancy of Neu-induced mammary tumors over-expressing active transforming growth factor beta1
    • Muraoka RS, Koh Y, Roebuck LR, et al. Increased malignancy of Neu-induced mammary tumors over-expressing active transforming growth factor beta1. Mol Cell Biol 2003;23:8691-703.
    • (2003) Mol Cell Biol , vol.23 , pp. 8691-8703
    • Muraoka, R.S.1    Koh, Y.2    Roebuck, L.R.3
  • 27
    • 0032571383 scopus 로고    scopus 로고
    • Prolactin receptor regulates Stat5 tyrosine phosphorylation and nuclear translocation by two separate pathways
    • Ali S, Ali S. Prolactin receptor regulates Stat5 tyrosine phosphorylation and nuclear translocation by two separate pathways. J Biol Chem 1998;273:7709-16.
    • (1998) J Biol Chem , vol.273 , pp. 7709-7716
    • Ali, S.1    Ali, S.2
  • 28
    • 0030051779 scopus 로고    scopus 로고
    • PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation
    • Ali S, Chen Z, Lebrun JJ, et al. PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation. EMBO J 1996;15:135-42.
    • (1996) EMBO J , vol.15 , pp. 135-142
    • Ali, S.1    Chen, Z.2    Lebrun, J.J.3
  • 30
    • 1342326910 scopus 로고    scopus 로고
    • Relevance of breast cancer cell lines as models for breast tumours: An update
    • Lacroix M, Leclercq G. Relevance of breast cancer cell lines as models for breast tumours: an update. Breast Cancer Res Treat 2004;83:249-89.
    • (2004) Breast Cancer Res Treat , vol.83 , pp. 249-289
    • Lacroix, M.1    Leclercq, G.2
  • 31
    • 0348134871 scopus 로고    scopus 로고
    • Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer
    • Ballestar E, Paz MF, Valle L, et al. Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. EMBO J 2003;22:6335-45.
    • (2003) EMBO J , vol.22 , pp. 6335-6345
    • Ballestar, E.1    Paz, M.F.2    Valle, L.3
  • 34
    • 84905500925 scopus 로고    scopus 로고
    • Tyrosine kinases as targets for cancer therapy
    • Levitzki A. Tyrosine kinases as targets for cancer therapy. Eur J Cancer 2002;38 Suppl 5:811-8.
    • (2002) Eur J Cancer , vol.38 , Issue.SUPPL. 5 , pp. 811-818
    • Levitzki, A.1
  • 35
    • 0028074204 scopus 로고
    • Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2
    • Zhuang H, Patel SV, He TC, Sonsteby SK, Niu Z, Wojchowski DM. Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2. J Biol Chem 1994;269:21411-4.
    • (1994) J Biol Chem , vol.269 , pp. 21411-21414
    • Zhuang, H.1    Patel, S.V.2    He, T.C.3    Sonsteby, S.K.4    Niu, Z.5    Wojchowski, D.M.6
  • 36
    • 0031919849 scopus 로고    scopus 로고
    • Jaks and STATs: Biological implications
    • Leonard WJ, O'Shea JJ. Jaks and STATs: biological implications. Annu Rev Immunol 1998;16:293-322.
    • (1998) Annu Rev Immunol , vol.16 , pp. 293-322
    • Leonard, W.J.1    O'Shea, J.J.2
  • 37
    • 0036128068 scopus 로고    scopus 로고
    • The role of mitogen-activated protein (MAP) kinase in breast cancer
    • Santen RJ, Song RX McPherson R, et al. The role of mitogen-activated protein (MAP) kinase in breast cancer. J Steroid Biochem Mol Biol 2002;80:239-56.
    • (2002) J Steroid Biochem Mol Biol , vol.80 , pp. 239-256
    • Santen, R.J.1    Song, R.X.2    McPherson, R.3
  • 39
    • 0242267055 scopus 로고    scopus 로고
    • Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways
    • Acosta JJ, Munoz RM, Gonzalez L, et al. Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways. Mol Endocrinol 2003;17:2268-82.
    • (2003) Mol Endocrinol , vol.17 , pp. 2268-2282
    • Acosta, J.J.1    Munoz, R.M.2    Gonzalez, L.3
  • 40
    • 9644268154 scopus 로고    scopus 로고
    • Multiple kinase cascades mediate prolactin signals to activating protein-1 in breast cancer cells
    • Gutzman JH, Rugowski DE, Schroeder MD, Watters JJ, Schuler LA. Multiple kinase cascades mediate prolactin signals to activating protein-1 in breast cancer cells. Mol Endocrinol 2004;18:3064-75.
    • (2004) Mol Endocrinol , vol.18 , pp. 3064-3075
    • Gutzman, J.H.1    Rugowski, D.E.2    Schroeder, M.D.3    Watters, J.J.4    Schuler, L.A.5
  • 41
    • 0034666839 scopus 로고    scopus 로고
    • Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells
    • Lehmann K, Janda E, Pierreux CE, et al. Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells. Genes Dev 2000;14:2610-22.
    • (2000) Genes Dev , vol.14 , pp. 2610-2622
    • Lehmann, K.1    Janda, E.2    Pierreux, C.E.3
  • 42
    • 0036304111 scopus 로고    scopus 로고
    • Metastasis is driven by sequential elevation of H-ras and Smad2 levels
    • Oft M, Akhurst RJ, Balmain A. Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nat Cell Biol 2002;4:487-94.
    • (2002) Nat Cell Biol , vol.4 , pp. 487-494
    • Oft, M.1    Akhurst, R.J.2    Balmain, A.3
  • 43
    • 1642278888 scopus 로고    scopus 로고
    • Collaborative activities of macrophage-stimulating protein and transforming growth factor-beta1 in induction of epithelial to mesenchymal transition: Roles of the RON receptor tyrosine kinase
    • Wang D, Shen Q, Chen YQ, Wang MH. Collaborative activities of macrophage-stimulating protein and transforming growth factor-beta1 in induction of epithelial to mesenchymal transition: roles of the RON receptor tyrosine kinase. Oncogene 2004;23:1668-80.
    • (2004) Oncogene , vol.23 , pp. 1668-1680
    • Wang, D.1    Shen, Q.2    Chen, Y.Q.3    Wang, M.H.4
  • 44
    • 13444263403 scopus 로고    scopus 로고
    • Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells
    • Sultan AS, Xie J, LeBaron MJ, Ealley EL, Nevalainen MT, Rui H. Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells. Oncogene 2005;24:746-60.
    • (2005) Oncogene , vol.24 , pp. 746-760
    • Sultan, A.S.1    Xie, J.2    LeBaron, M.J.3    Ealley, E.L.4    Nevalainen, M.T.5    Rui, H.6
  • 45
    • 0037264812 scopus 로고    scopus 로고
    • Metastasis suppressors alter the signal transduction of cancer cells
    • Steeg PS. Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 2003;3:55-63.
    • (2003) Nat Rev Cancer , vol.3 , pp. 55-63
    • Steeg, P.S.1
  • 46
    • 0037980379 scopus 로고    scopus 로고
    • Metastasis suppressor pathways: An evolving paradigm
    • Shevde LA, Welch DR. Metastasis suppressor pathways: an evolving paradigm. Cancer Lett 2003;198:1-20.
    • (2003) Cancer Lett , vol.198 , pp. 1-20
    • Shevde, L.A.1    Welch, D.R.2
  • 47
    • 0037199995 scopus 로고    scopus 로고
    • Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway
    • Hartsough MT, Morrison DK, Salerno M, et al. Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway. J Biol Chem 2002;277:32389-99.
    • (2002) J Biol Chem , vol.277 , pp. 32389-32399
    • Hartsough, M.T.1    Morrison, D.K.2    Salerno, M.3
  • 48
    • 0034710619 scopus 로고    scopus 로고
    • Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1
    • Odintsova E, Sugiura T, Berditchevski F. Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1. Curr Biol 2000;10:1009-12.
    • (2000) Curr Biol , vol.10 , pp. 1009-1012
    • Odintsova, E.1    Sugiura, T.2    Berditchevski, F.3
  • 49
    • 0344393408 scopus 로고    scopus 로고
    • Regulation of MAP kinase signaling modules by scaffold proteins in mammals
    • Morrison DK, Davis RJ. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu Rev Cell Dev Biol 2003;19:91-118.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 91-118
    • Morrison, D.K.1    Davis, R.J.2
  • 50
    • 10344258041 scopus 로고    scopus 로고
    • Targeting the mitogen-activated protein kinase cascade to treat cancer
    • Sebolt-Leopold JS, Herrera R. Targeting the mitogen-activated protein kinase cascade to treat cancer. Nat Rev Cancer 2004;4:937-47.
    • (2004) Nat Rev Cancer , vol.4 , pp. 937-947
    • Sebolt-Leopold, J.S.1    Herrera, R.2
  • 51
    • 2042538029 scopus 로고    scopus 로고
    • Structure and regulation of MAPK phosphatases
    • Farooq A, Zhou MM. Structure and regulation of MAPK phosphatases. Cell Signal 2004;16:769-79.
    • (2004) Cell Signal , vol.16 , pp. 769-779
    • Farooq, A.1    Zhou, M.M.2
  • 52
    • 0036142091 scopus 로고    scopus 로고
    • The RAS effector RTN1 directly competes with RAF and is regulated by 14-3-3 proteins
    • Wang Y, Waldron RT, Dhaka A, et al. The RAS effector RTN1 directly competes with RAF and is regulated by 14-3-3 proteins. Mol Cell Biol 2002;22:916-26.
    • (2002) Mol Cell Biol , vol.22 , pp. 916-926
    • Wang, Y.1    Waldron, R.T.2    Dhaka, A.3
  • 53
    • 0033539167 scopus 로고    scopus 로고
    • Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP
    • Yeung K, Seitz T, Li S, et al. Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP. Nature 1999;401:173-7.
    • (1999) Nature , vol.401 , pp. 173-177
    • Yeung, K.1    Seitz, T.2    Li, S.3
  • 54
    • 1642471746 scopus 로고    scopus 로고
    • Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP
    • Matheny SA, Chen C, Kortum RL, Razidlo GL, Lewis RE, White MA. Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP. Nature 2004;427:256-60.
    • (2004) Nature , vol.427 , pp. 256-260
    • Matheny, S.A.1    Chen, C.2    Kortum, R.L.3    Razidlo, G.L.4    Lewis, R.E.5    White, M.A.6
  • 55
    • 0036847930 scopus 로고    scopus 로고
    • Sproutyl and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway
    • Hanafusa H, Torii S, Yasunaga T, Nishida E. Sproutyl and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. Nat Cell Biol 2002;4:850-8.
    • (2002) Nat Cell Biol , vol.4 , pp. 850-858
    • Hanafusa, H.1    Torii, S.2    Yasunaga, T.3    Nishida, E.4
  • 56
    • 0035833471 scopus 로고    scopus 로고
    • Spred is a Sprouty-related suppressor of Ras signalling
    • Wakioka T, Sasaki A, Kato R, et al. Spred is a Sprouty-related suppressor of Ras signalling. Nature 2001;412:647-51.
    • (2001) Nature , vol.412 , pp. 647-651
    • Wakioka, T.1    Sasaki, A.2    Kato, R.3
  • 57
    • 0031459864 scopus 로고    scopus 로고
    • p62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
    • Carpino N, Wisniewski D, Strife A, et al. p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell 1997;88:197-204.
    • (1997) Cell , vol.88 , pp. 197-204
    • Carpino, N.1    Wisniewski, D.2    Strife, A.3
  • 58
    • 0031444245 scopus 로고    scopus 로고
    • Identification of the Abl-and rasGAP-associated 62 kDa protein as a docking protein, Dok
    • Yamanashi Y, Baltimore D. Identification of the Abl-and rasGAP-associated 62 kDa protein as a docking protein, Dok. Cell 1997;88:205-11.
    • (1997) Cell , vol.88 , pp. 205-211
    • Yamanashi, Y.1    Baltimore, D.2
  • 59
    • 0345826090 scopus 로고    scopus 로고
    • Jak2 tyrosine kinase mediates angiotensin II-dependent inactivation of ERK2 via induction of mitogen-activated protein kinase phosphatase 1
    • Sandberg EM, Ma X VonDerLinden D, Godeny MD, Sayeski PP. Jak2 tyrosine kinase mediates angiotensin II-dependent inactivation of ERK2 via induction of mitogen-activated protein kinase phosphatase 1. J Biol Chem 2004;279:1956-67.
    • (2004) J Biol Chem , vol.279 , pp. 1956-1967
    • Sandberg, E.M.1    Ma, X.2    VonDerlinden, D.3    Godeny, M.D.4    Sayeski, P.P.5
  • 60
    • 17444377587 scopus 로고    scopus 로고
    • JAKing up hematopoietic proliferation
    • Shannon K, Van Etten RA. JAKing up hematopoietic proliferation. Cancer Cell 2005;7:291-3.
    • (2005) Cancer Cell , vol.7 , pp. 291-293
    • Shannon, K.1    Van Etten, R.A.2
  • 62
    • 1542327277 scopus 로고    scopus 로고
    • Inhibitors of JAKs/STATs and the kinases: A possible new cluster of drugs
    • Luo C, Laaja P. Inhibitors of JAKs/STATs and the kinases: a possible new cluster of drugs. Drug Discov Today 2004;9:268-75.
    • (2004) Drug Discov Today , vol.9 , pp. 268-275
    • Luo, C.1    Laaja, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.