p62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

Cell

Volumn 88, Issue 2, 1997, Pages 197-204

  Carpino, Nick ^a,b   Wisniewski, David ^c   Strife, Annabel ^c   Marshak, Daniel ^a,d,e   Kobayashi, Ryuji ^a   Stillman, Bruce ^a   Clarkson, Bayard ^b  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d OSIRIS THERAPEUTICS INC   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RAS PROTEIN; TYROSINE;

ARTICLE; CELL DIFFERENTIATION; CHRONIC MYELOID LEUKEMIA; ENZYME ACTIVITY; GROWTH REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 0031459864     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81840-1     Document Type: Article

References (41)

1. Avanzi, G.C., Lista, P., Giovinazzo, B., Miniero, R., Saglio, G., Benetton, G., Coda, R., Cattoretti, G., and Pegoraro, L. (1988). Selective growth response to IL-3 of a human leukemic cell line with mega-karyoblastic features. Br. J. Haematol. 69, 359-366.
2. Bolen, J.B., Rowley, B., Spana, C., and Tsygankov, A. (1992). The Src family of tyrosine protein kinases in hematopoietic signal transduction. FASEB J. 6, 3403-3409.
3. Chung, S., and Wong, P.M.C. (1995).The biology of abl during hemopoietic stem cell differentiation and development. Oncogene 10, 1261-1268.
4. Clarkson B., and Strife, A. (1993). Linkage of proliferative and maturational abnormalities in chronic myelogenous leukemia and relevance to treatment. Leukemia 7, 1683-1721.
5. Cohen, G.B., Ren, R., and Baltimore, D. (1995). Modular binding domains in signal transduction proteins. Cell 80, 237-248.
6. Daley G.Q., and Ben Neriah, Y. (1991). Implicating the bcr/abl gene in the pathogenesis of Philadelphia chromosome-positive human leukemia. Adv. Cancer Res. 57, 151-184.
7. Ellis, C., Moran, M., McCormick, F., and Pawson, T. (1990). Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 343, 377-381.
8. Filvaroff, E., Calautti, E., McCormick, F., and Dotto, G.P. (1992). Specific changes of ras GTPase-activating protein (GAP)and a GAP-associated p62 protein during calcium-induced keratinocyte differentiation. Mol. Cell Biol. 12, 5319-5328.
9. Galli, S.J., Zsebo, K.M., and Geissler, E. (1994). The kit ligand, stem cell factor. Adv. Immunol. 55, 1-96.
10. Garrels, J. (1983). Quantitative two-dimensional gel electrophoresis of proteins. In Methods in Enzymology 100: Recombinant DNA(b), R. Wu, L. Grossman, and K. Moldave, eds. (San Diego, California: Academic Press), pp. 411-423.
11. Groffen, J., Morris, C., and Heisterkamp, N. (1991). The Philadelphia chromosome translocation. In Chronic Myelogenous Leukemia - Molecular Approaches to Research and Therapy, A.B. Deisseroth and R.B. Arlinghaus, eds. (New York: Marcel Dekker), pp. 181-207.
12. Harlow, E., and Lane, D. (1988). Antibodies: A Laboratory Manual (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
13. Konopka, J., Watanabe, S.M., and Witte, O.N. (1984). An alteration of the human c-Abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell 37, 1035-1042.
14. Kozma, L.M., Rossomando, A.J., and Weber, M.J. (1991). Comparison of three methods for detecting tyrosine phosphorylated proteins. Methods Enzymol. 201, 28-43.
15. Lemmon, M.A., Ferguson, K.M., and Schlessinger, J. (1996). PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell 85, 621-624.
16. Lock, P., Fumagalli, S., Polakis, P., McCormick, F., and Courtneidge, S.A. (1996). The human p62 cDNA encodes Sam68 and not the rasGAP-associated p62 protein. Cell 84, 23-24.
17. Lugo, T.G., Pendergast, A.M., Muller, A.J., and Witte, O.N. (1990). Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 247, 1079-1082.
18. Marengere, L.E.M., and Pawson, T. (1992). Identification of residues in GTPase-activating protein src homology 2 domains that control binding totyrosine phosphorylated growth factor receptors and p62. J. Biol. Chem. 267, 22779-22786.
19. McGlade, J., Brunkhorst, B., Anderson, D., Mbamalu, G., Settleman, J., Dedhar, S., Rozakis-Adcock, M., Chen, L.B., and Pawson, T. (1993). The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion. EMBO J. 12, 3073-3081.
20. McNiece, I.K., Langley, K.E., and Zsebo, K.M. (1991). Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3, and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp. Hematol. 19, 226-231.
21. McWhirter, J.R., and Wang, J.Y.J. (1991). Activation of tyrosine kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins. Mol. Cell Biol. 11, 1553-1565.
22. Moran, M.F., Polakis, P., McCormick, F., Pawson, T., and Ellis, C. (1991). Protein tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein. Mol. Cell Biol. 11, 1804-1812.
23. Musacchio, A., Gibson, T., Rice, P., Thompson, J., and Saraste, M. (1993). The PH domain: a common piece in the structural pathwork of signalling proteins. Trends Biochem. Sci. 18, 343-348.
24. Neet, K., and Hunter T. (1995). The nonreceptor protein-tyrosine kinase csk complexes directly with the GTPase-activating protein-associated p62 in cells expressing v-src or activated c-src. Mol. Cell Biol. 15, 4908-4920.
25. Pawson, T. (1995). Protein modules and signaling networks. Nature 373, 573-580.
26. Sambrook, J., Fritsch, E., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, Second Edition (Cold Spring Harbor: Cold Spring Harbor Laboratory Press).
27. Sawyers, C.L., Denny, C.T., and Witte, O.N. (1991). Leukemia and the disruption of normal hematopoiesis. Cell 64, 337-350.
28. Skowronski, J., Fanning, T., and Singer, M. (1988). Unit-length line-1 transcripts in human teratocarcinoma cells. Mol. Cell Biol. 8, 1385-1397.
29. Songyang, Z, Shoelson, S.E., McGlade, J., Olivier, P., Pawson, T., Bustelo, X.R., Barbacid, M., Sabe, H., Hanafusa, H., Yi, T., et al. (1994). Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol. Cell Biol. 14, 2777-2785.
30. Songyang, Z., Carraway, K.L., III, Eck, M.J., Harrison, S.C., Feldman, R.A., Mohammadl, M., Schlessinger, J., Hubbard, S.R., Smith, D.P., Eng, C.,et al. (1995). Catalytic specificity of protein tyrosine kinases is critical for selective signalling. Nature 373, 536-539.
31. Strife, A., Perez, A., Lambek, C., Wisniewski, D., Bruno, S., Darzynkiewicz, Z., and Clarkson, B. (1993). Characterization of lineage-negative blast subpopulations derived from normal and chronic myelogenous leukemia bone marrows and determination of their responsiveness to human c-kit ligand. Cancer Res. 53, 401-409.
32. Trahey, M., and McCormick, F. (1987). A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science 238, 542-545.
33. Valius, M., Secrist, J.P., and Kaslauskas, A. (1995). The GTPase-activating protein of ras suppresses platelet-derived growth factor receptor signaling by silencing phospholipase C-1. Mol. Cell Biol. 15, 3058-3071.
34. van der Geer, P., Luo, K., Sefton, B.M., and Hunter, T. (1993). Phosphopeptide mapping and phosphoamino acid analysis on cellulose thin-layer plates. In Protein Phosphorylation, A Practical Approach, D. Grahame Hardie, ed. (Oxford, England: IRL Press), pp. 31-59.
35. van der Geer, P., Hunter, T., and Lindberg, R.A. (1994). Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell. Biol. 10, 251-337.
36. Wang R., Kobayashi, R., and Bishop, J.M. (1996). Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor. Proc. Natl. Acad. Sci. USA 93, 8425-8430.
37. Wisniewski, D., Strife, A., Wojciechowicz, D., Lambek, C., and Clarkson B. (1994). A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations. Leukemia 8, 688-693.
38. Wisniewski, D., Strife, A., Berman, E., and Clarkson, B. (1996). c-kit ligand stimulates tyrosine phosphorylation of a similiar pattern of phosphotyrosyl proteins in primary primitive normal hematopoietic progenitors that are constitutively phosphorylated in comparable primitive progenitors in chronic phase chronic myelogneous leukemia. Leukemia 10, 229-237.
39. Wong, G., Muller, O., Clark, R., Conroy, L., Moran, M., Polakis, P., and McCormick, F. (1992). Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell 69, 551-558.
40. Yamanashi, Y., and Baltimore, D. (1997). Identification of the Abl-and rasGAP-associated 62 kDa protein as a docking protein, Dok. Cell, this issue.
41. Yu, H., Chen, J.K., Feng, S., Dalgarno, D.C., Brauer, A.W., and Schreiber, S.L. (1994). Structural basis for the binding of prolinerich peptides to SH3 domains. Cell 76, 933-945.