-
1
-
-
0032577051
-
The croonian lecture, 1997. The phosphorylation of proteins on tyrosine: Its role in cell growth and disease
-
Hunter, T. The croonian lecture, 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease. Phil. Trans. R. Soc. Lond. B. 353, 583-605 (1998).
-
(1998)
Phil. Trans. R. Soc. Lond. B
, vol.353
, pp. 583-605
-
-
Hunter, T.1
-
2
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger, J. Cell signaling by receptor tyrosine kinases. Cell 103, 211-225 (2000).
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
3
-
-
0033032591
-
Signaling networks-do all roads lead to the same genes?
-
Pawson, T. & Saxton, T. M. Signaling networks-do all roads lead to the same genes? Cell 97, 675-678 (1999).
-
(1999)
Cell
, vol.97
, pp. 675-678
-
-
Pawson, T.1
Saxton, T.M.2
-
4
-
-
0034730323
-
Receptor tyrosine kinases: Specific outcomes from general signals
-
Simon, M. A. Receptor tyrosine kinases: specific outcomes from general signals. Cell 103, 13-15 (2000).
-
(2000)
Cell
, vol.103
, pp. 13-15
-
-
Simon, M.A.1
-
5
-
-
0034614490
-
Signaling-2000 and beyond
-
Hunter, T. Signaling-2000 and beyond. Cell 100, 113-127 (2000).
-
(2000)
Cell
, vol.100
, pp. 113-127
-
-
Hunter, T.1
-
6
-
-
0034676456
-
Feedback control of intercellular signalling in development
-
Freeman, M. Feedback control of intercellular signalling in development. Nature 408, 313-319 (2000).
-
(2000)
Nature
, vol.408
, pp. 313-319
-
-
Freeman, M.1
-
7
-
-
0033515519
-
Negative feedback mechanisms and their roles during pattern formation
-
Perrimon, N. & McMahon, A. P. Negative feedback mechanisms and their roles during pattern formation. Cell 97, 13-16 (1999).
-
(1999)
Cell
, vol.97
, pp. 13-16
-
-
Perrimon, N.1
McMahon, A.P.2
-
8
-
-
0029671192
-
Argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop
-
Golembo, M., Schweitzer, R., Freeman, M. & Shilo, B. Z. argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop. Development 122, 223-230 (1996).
-
(1996)
Development
, vol.122
, pp. 223-230
-
-
Golembo, M.1
Schweitzer, R.2
Freeman, M.3
Shilo, B.Z.4
-
9
-
-
0033582934
-
The transmembrane molecule kekkon 1 acts in a feedback loop to negative regulate the activity of the Drosophila EGF receptor during oogenesis
-
Ghiglione, C. et al. The transmembrane molecule kekkon 1 acts in a feedback loop to negative regulate the activity of the Drosophila EGF receptor during oogenesis. Cell 96, 847-856 (1999).
-
(1999)
Cell
, vol.96
, pp. 847-856
-
-
Ghiglione, C.1
-
10
-
-
0030611757
-
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
-
Nakao, A. et al. Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling. Nature 389, 631-635 (1997).
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
-
11
-
-
0034082217
-
Negative regulation of cytokine signaling pathways
-
Yasukawa, H., Sasaki, A. & Yoshimura, A. Negative regulation of cytokine signaling pathways. Annu. Rev. Immunol. 18, 143-164 (2000).
-
(2000)
Annu. Rev. Immunol
, vol.18
, pp. 143-164
-
-
Yasukawa, H.1
Sasaki, A.2
Yoshimura, A.3
-
12
-
-
0036170142
-
Identification of Sef, a novel modulator of FGF signaling
-
Tsang, M., Friesel, R., Kudoh, T. & Dawid, I. B. Identification of Sef, a novel modulator of FGF signaling. Nat. Cell Biol. 4, 165-169 (2002).
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 165-169
-
-
Tsang, M.1
Friesel, R.2
Kudoh, T.3
Dawid, I.B.4
-
13
-
-
0036173032
-
Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signaling
-
Furthauer, M., Lin, W., Ang, S.-L., Thisse, B. & Thisse, C. Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signaling. Nat. Cell Biol. 4, 170-174 (2002).
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 170-174
-
-
Furthauer, M.1
Lin, W.2
Ang, S.-L.3
Thisse, B.4
Thisse, C.5
-
14
-
-
0032559228
-
Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
-
Hacohen, N., Kramer, S., Sutherland, D., Hiromi, Y. & Krasnow, M. A. sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 92, 253-263 (1998).
-
(1998)
Cell
, vol.92
, pp. 253-263
-
-
Hacohen, N.1
Kramer, S.2
Sutherland, D.3
Hiromi, Y.4
Krasnow, M.A.5
-
15
-
-
0033525895
-
Sprouty, an intracellular inhibitor of Ras signalling
-
Casci, T., Vinos, J. & Freeman, M. Sprouty, an intracellular inhibitor of Ras signalling. Cell 96, 655-665 (1999).
-
(1999)
Cell
, vol.96
, pp. 655-665
-
-
Casci, T.1
Vinos, J.2
Freeman, M.3
-
16
-
-
0033035109
-
Sprouty: A common antagonist of FGF and EGF signaling pathways in Drosophila
-
Kramer, S., Okabe, M., Hacohen, N., Krasnow, M. A. & Hiromi, Y. Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. Development 126, 2515-2525 (1999).
-
(1999)
Development
, vol.126
, pp. 2515-2525
-
-
Kramer, S.1
Okabe, M.2
Hacohen, N.3
Krasnow, M.A.4
Hiromi, Y.5
-
17
-
-
0032841608
-
Sprouty is a general inhibitor of receptor tyrosine kinase signaling
-
Reich, A., Sapir, A. & Shilo, B. Z. Sprouty is a general inhibitor of receptor tyrosine kinase signaling. Development 126, 4139-4147 (1999).
-
(1999)
Development
, vol.126
, pp. 4139-4147
-
-
Reich, A.1
Sapir, A.2
Shilo, B.Z.3
-
18
-
-
0032719944
-
Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed
-
Minowada, G., et al. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126, 4465-4475 (1999).
-
(1999)
Development
, vol.126
, pp. 4465-4475
-
-
Minowada, G.1
-
19
-
-
0032933938
-
Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo
-
de Maximy, A. A. et al. Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo. Mech. Dev. 81, 213-216 (1999).
-
(1999)
Mech. Dev
, vol.81
, pp. 213-216
-
-
de Maximy, A.A.1
-
20
-
-
0033999596
-
Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling
-
Chambers, D. & Mason, I. Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling. Mech. Dev. 91, 361-364 (2000).
-
(2000)
Mech. Dev
, vol.91
, pp. 361-364
-
-
Chambers, D.1
Mason, I.2
-
21
-
-
0035056454
-
Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis
-
Mailleux, A. A. et al. Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis. Mech. Dev. 102, 81-94 (2001).
-
(2001)
Mech. Dev
, vol.102
, pp. 81-94
-
-
Mailleux, A.A.1
-
22
-
-
0033602147
-
Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis
-
Tefft, J. D. et al. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr. Biol. 9, 219-222 (1999).
-
(1999)
Curr. Biol
, vol.9
, pp. 219-222
-
-
Tefft, J.D.1
-
23
-
-
0035336772
-
Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning
-
Nutt, S. L., Dingwell, K. S., Holt, C. E. & Amaya, E. Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning. Genes Dev. 15, 1152-1166 (2001).
-
(2001)
Genes Dev
, vol.15
, pp. 1152-1166
-
-
Nutt, S.L.1
Dingwell, K.S.2
Holt, C.E.3
Amaya, E.4
-
24
-
-
0035830916
-
Inhibition of angiogenesis by a mouse sprouty protein
-
Lee, S. H., Schloss, D. J., Jarvis, L., Krasnow, M. A. & Swain, J. L. Inhibition of angiogenesis by a mouse sprouty protein. J. Biol. Chem. 276, 4128-4133 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 4128-4133
-
-
Lee, S.H.1
Schloss, D.J.2
Jarvis, L.3
Krasnow, M.A.4
Swain, J.L.5
-
25
-
-
0035809919
-
Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells
-
Impagnatiello, M. A. et al. Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. J. Cell Biol. 152, 1087-1098 (2001).
-
(2001)
J. Cell Biol
, vol.152
, pp. 1087-1098
-
-
Impagnatiello, M.A.1
-
26
-
-
0035824694
-
Mammalian Sprouty proteins inhibit cell growth and differentiation by preventing Ras activation
-
Gross, I., Bassit, B., Benezra, M. & Licht, J. D. Mammalian Sprouty proteins inhibit cell growth and differentiation by preventing Ras activation. J. Biol. Chem. 276, 46460-46468 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 46460-46468
-
-
Gross, I.1
Bassit, B.2
Benezra, M.3
Licht, J.D.4
-
27
-
-
0034931142
-
Sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish
-
Furthauer, M., Reifers, F., Brand, M., Thisse, B. & Thisse, C. Sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish. Development 128, 2175-2186 (2001).
-
(2001)
Development
, vol.128
, pp. 2175-2186
-
-
Furthauer, M.1
Reifers, F.2
Brand, M.3
Thisse, B.4
Thisse, C.5
-
28
-
-
0036479310
-
Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf
-
Yusoff, P. et al. Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf. J. Biol. Chem. 277, 3195-3201 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 3195-3201
-
-
Yusoff, P.1
-
29
-
-
0035965203
-
Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation
-
Sasaki, A., Taketomi, T., Wakioka, T., Kato, R. & Yoshimura, A. Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation. J. Biol. Chem. 276, 36804-36808 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 36804-36808
-
-
Sasaki, A.1
Taketomi, T.2
Wakioka, T.3
Kato, R.4
Yoshimura, A.5
-
30
-
-
0026484261
-
SH2 and SH3 domains: From structure to function
-
Pawson, T. & Gish, G. D. SH2 and SH3 domains: from structure to function. Cell 71, 359-362 (1992).
-
(1992)
Cell
, vol.71
, pp. 359-362
-
-
Pawson, T.1
Gish, G.D.2
-
31
-
-
0030706168
-
A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
-
Kouhara, H. et al. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89, 693-702 (1997).
-
(1997)
Cell
, vol.89
, pp. 693-702
-
-
Kouhara, H.1
-
32
-
-
0026608178
-
C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains
-
Scott, S. G., Stern, M. J. & Horvitz, H. R. C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature 356, 340-344 (1992).
-
(1992)
Nature
, vol.356
, pp. 340-344
-
-
Scott, S.G.1
Stern, M.J.2
Horvitz, H.R.3
-
33
-
-
0034865053
-
Xenopus FRS2 is involved in early embryogenesis in cooperation with the Src family kinase Laloo
-
Kusakabe, M., Masuyama, N., Hanafusa, H. & Nishida, E. Xenopus FRS2 is involved in early embryogenesis in cooperation with the Src family kinase Laloo. EMBO Reports 2, 727-735 (2001).
-
(2001)
EMBO Reports
, vol.2
, pp. 727-735
-
-
Kusakabe, M.1
Masuyama, N.2
Hanafusa, H.3
Nishida, E.4
-
34
-
-
0034693130
-
Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation
-
Lim, J. et al. Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. J. Biol. Chem. 275, 32837-32845 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 32837-32845
-
-
Lim, J.1
-
35
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C. J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185 (1995).
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
36
-
-
0031835659
-
Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation
-
Hadari, Y. R., Kouhara, H., Lax, I. & Schlessinger, J. Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation. Mol. Cell Biol. 18, 3966-3973 (1998).
-
(1998)
Mol. Cell Biol
, vol.18
, pp. 3966-3973
-
-
Hadari, Y.R.1
Kouhara, H.2
Lax, I.3
Schlessinger, J.4
-
37
-
-
0035937167
-
Evidence for direct interaction between Sprouty and Cbl
-
Wong, E. S. M., Lim, J., Low, B. C., Chen, Q. & Guy, G. R. Evidence for direct interaction between Sprouty and Cbl. J. Biol. Chem. 276, 5866-5875 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 5866-5875
-
-
Wong, E.S.M.1
Lim, J.2
Low, B.C.3
Chen, Q.4
Guy, G.R.5
-
38
-
-
0032723268
-
Caveolins, liquid-ordered domains, and signal transduction
-
Smart, E. J. et al. Caveolins, liquid-ordered domains, and signal transduction. Mol. Cell Biol. 19, 7289-7304 (1999).
-
(1999)
Mol. Cell Biol
, vol.19
, pp. 7289-7304
-
-
Smart, E.J.1
-
39
-
-
0037076329
-
FRS2α attenuates FGF receptor signalling by Grb2-mediated recruitment of the ubiquitin ligase Cbl
-
Wong, A., Lamothe, B., Lee, A., Schlessinger, J. & Lax, I. FRS2α attenuates FGF receptor signalling by Grb2-mediated recruitment of the ubiquitin ligase Cbl. Proc. Natl. Acad. Sci. USA 99, 6684-6689 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6684-6689
-
-
Wong, A.1
Lamothe, B.2
Lee, A.3
Schlessinger, J.4
Lax, I.5
-
40
-
-
0033536637
-
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase
-
Joazeiro, C. A. P. et al. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. Science 286, 309-312 (1999).
-
(1999)
Science
, vol.286
, pp. 309-312
-
-
Joazeiro, C.A.P.1
-
41
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P. et al. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370, 527-532 (1994).
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
-
42
-
-
0034232293
-
The TGF-β family member derriere is involved in regulation of the establishment of left-right asymmetry
-
Hanafusa, H., Masuyama, N., Kusakabe, M., Shibuya, H. & Nishida, E. The TGF-β family member derriere is involved in regulation of the establishment of left-right asymmetry. EMBO Rep. 1, 32-39 (2000).
-
(2000)
EMBO Rep
, vol.1
, pp. 32-39
-
-
Hanafusa, H.1
Masuyama, N.2
Kusakabe, M.3
Shibuya, H.4
Nishida, E.5
|