PTP1D is a positive regulator of the prolactin signal leading to β-casein promoter activation

EMBO Journal

Volumn 15, Issue 1, 1996, Pages 135-142

  Ali, Suhad ^a   Chen, Zhengjun ^a   Lebrun, Jean Jacques ^b,c   Vogel, Wolfgang ^a   Kharitonenkov, Alexei ^a   Kelly, Paul A ^b   Ullrich, Axel ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b INSERM   (France)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Jak2; Phosphatase 1D; Prolactin; Prolactin receptor; Protein tyrosine; Signal transduction

Indexed keywords

BETA CASEIN; CYTOKINE RECEPTOR; CYTOPLASM PROTEIN; GROWTH HORMONE RECEPTOR; MILK PROTEIN; PROLACTIN; PROLACTIN RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ARTICLE; CELL MUTANT; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME DEFICIENCY; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MILK PRODUCTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RAT; REPORTER GENE; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0030051779     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00341.x     Document Type: Article

References (61)

1. Adachi, M., Sekiya, M., Miyachi, T., Matsuno, K., Hinoda, Y., Imai, K. and Yachi, A. (1992) Molecular cloning of a novel protein-tyrosine phosphatase SH-PTP3 with sequence similarity to the src-homology region 2. FEBS Lett., 314, 335-339
2. Ahmad, S., Banville, D., Zhao, Z., Fischer, E.H. and Shen, S.H. (1993) A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains. Proc. Natl Acad. Sci. USA, 90, 2197-2201.
3. Ali, S., Pellegrini, I. and Kelly, P.A. (1991) A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor. J. Biol. Chem., 266, 20110-420117.
4. Ali, S., Edery, M., Pellegrini, J., Lesueur, L., Paly, J., Djiane, J. and Kelly, P.A. (1992) The Nb2 form of prolactin receptor is able to activate a milk protein gene promoter. Mol. Endocrinol., 6, 1242-1248.
5. Bazan, F. (1989) A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and p75 IL-2 receptor β-chain. Biochem. Biophys. Res Commun., 164, 788-795.
6. Bennett, A.M., Tang, T.L., Sugimoto, S., Walsh, C.T. and Neel, B.G. (1994) Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras Proc. Natl Acad. Sci. USA, 91, 7335-7339.
7. Boulton, T.G., Stahl, N. and Yancopoulos, G.D. (1994) Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors. J. Biol. Chem., 269, 11648-11655.
8. Boutin, J.M. et al. (1988) Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family. Cell, 53, 69-77.
9. Campbell, G.S., Argetsinger, L.S., Ihle, J.N., Kelly, P.A., Rillema, J.A. and Carter-Su, C. (1994) Activation of Jak2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants Proc. Natl Acad. Sci. USA, 91, 5232-5236.
10. Case, R.D., Piccione, E., Wolf, G., Benett, A.M., Lechleider, R.J., Neel, B.G. and Shoelson, S.E. (1994) SH-PTP2/Syp SH2 domain binding specificity is defined by direct interactions with platelet-derived growth factor beta-receptor, epidermal growth factor receptor, and insulin receptor substrate-1-derived phosphopeptides. J. Biol. Chem., 269, 10467-10474.
11. Charbonneau, H., and Tonks, N.K. (1992) 1002 protein phosphatases? Annu Rev Cell Biol., 8, 463-493
12. Da Silva, L., Howard, O.M., Rui, H., Kirken, R.A. and Farrar, W.L. (1994) Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors. J Biol. Chem., 269, 18267-18270.
13. Doppler, W. (1994) Regulation of gene expression by prolactin. Rev. Physiol Biochem Pharmacol., 124, 93-130
14. Dusanter-Fourt, I. et al. (1994) Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells EMBO J., 13, 2583-2591.
15. Feng, G.S., Hui, C.C. and Pawson, T. (1993) SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science, 259, 1607-1611.
16. Freeman, R.M., Jr. Plutzky, J. and Neel, B.G. (1992) Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc. Natl Acad. Sci. USA, 89, 11239-11243.
17. Gouilleux, F., Wakao, H., Mundt, M. and Groner, B. (1994) Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J., 13, 4361-4369
18. Gout, P.W., Beer, C.T. and Noble, R.L. (1980) Prolactin-stimulated growth of cell cultures established from malignant Nb rat lymphomas. Cancer Res., 40, 2433-2436.
19. Ihle, J.N., Witthuhn, B.A., Quelle, F.W., Yamamoto, K., Thierfelder, W.E., Kreider, B. and Silvennoinen, O. (1994) Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem. Sci., 19, 222-227.
20. Kazlauskas, A., Feng, G.S., Pawson, T. and Valius, M. (1993) The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. Proc. Natl Acad Sci. USA, 90, 6939-6943.
21. Kelly, P.A. et al (1993) The growth hormone/prolactin receptor family. Recent Prog. Hormone Res., 48, 123-164
22. Kharitonenkov, A., Schnekenburger, J., Chen, Z., Knyazev, P., Ali, S., Zwick, E., White, M. and Ullrich, A. (1995) Adapter function of the protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction. J. Biol. Chem., 270, in press.
23. Klingmüller, U., Lorenz, U., Cantley, L.C., Neel, B.G. and Lodish, H.F. (1995) Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferation signals. Cell, 80, 729-738.
24. Kuhne, M.R., Pawson, T., Lienhard, G.E. and Feng, G.S. (1993) The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp. J. Biol. Chem., 268, 11479-11481.
25. Larner, A.C., David, M., Feldman, G.M., Igarashi, K.-I., Hackett, R.H., Webb, D.S.A., Sweitzer, S.M., Petricoin, E.F. and Finbloom, D.S. (1993) Tyrosine phosphorylation of DNA binding proteins by multiple cytokines. Science, 261, 1730-1733.
26. Lebrun, J.-J., Ali, S., Sofer, L., Ullrich, A. and Kelly, P.A. (1994) Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase Jak2. J. Biol. Chem., 269, 14021-14026.
27. Lebrun, J.-J., Ali, S., Ullrich, A. and Kelly, P.A. (1995a) Proline-rich sequence-mediated Jak2 association to the prolactin receptor is required but not sufficient for signal transduction. J. Biol. Chem., 270, 10664-10670.
28. Lebrun, J.-J., Ali, S., Goffin, V., Ullrich, A. and Kelly, P.A. (1995b) A single phosphotyrosine residue of the prolactin receptor is reponsible for activation of gene transcription. Proc. Natl Acad. Sci. USA, 92, 4031-4035.
29. Lechleider, R.J., Freeman, R.M. and Neel, B.G. (1993a) Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2. J. Biol Chem., 268, 13434-13438.
30. Lechleider, R.J., Sugimoto, S., Bennett, A.M., Kashishian, A.S., Cooper, J.A., Shoelson, S.E., Walsh, C.T. and Neel, B.G. (1993b) Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor. J. Biol. Chem., 268, 21478-21481.
31. Lesueur, L., Edery, M., Ali, S., Paly, J., Kelly, P.A. and Djiane, J. (1991) Comparison of long and short forms of the prolactin receptor on prolactin-induced milk protein gene. Proc. Natl Acad. Sci. USA, 88, 824-828.
32. Li, W., Nishimura, R., Kashishian, A., Batzer, A.G., Kim, W.J., Cooper, J.A. and Schlessinger, J. (1994) A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. Mol. Cell. Biol., 14, 509-517.
33. Marengere, L.E. and Pawson, T. (1992) Identification of residues in GTPase-activating protein Src homology 2 domains that control binding to tyrosine phosphorylated growth factor receptors and p62. J. Biol. Chem., 267, 22779-22786.
34. Matthews, R.J., Bowne, D.B., Flores, E. and Thomas, M.L. (1992) Characterization of hematopoietic protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences. Mol. Cell. Biol., 12, 2396-2405.
35. Milarski, K.L. and Saltiel, A.R. (1994) Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J Biol. Chem., 269, 21239-21243.
36. Miura, O., Nakamura, N., Quelle, F.W., Witthuhn, B.A., Ihle, J.N. and Aoki, N. (1994) Erythropoietin induces association of the JAK2 protein tyrosine kinase with the erythropoietin receptor in vivo. Blood, 84, 1501-1507.
37. Noguchi, T., Matozaki, T., Horita, K., Fujioka, Y. and Kasuga, M. (1994) Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation. Mol. Cell. Biol., 14, 6674-6682.
38. O'Neal, K.D. and Yu-Lee, L.Y. (1994) Differential signal transduction of the short, Nb2, and long prolactin receptors. Activation of interferon regulatory factor-1 and cell proliferation. J. Biol. Chem., 269, 26076-26082.
39. Pawson, T. and Gish, G.D. (1992) SH2 and SH3 domains: from structure to function. Cell, 71, 359-362.
40. Perkins, L.A., Larson, I. and Perrimon, N. (1992) corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell, 70, 225-236.
41. Plutzky, J., Neel, B.G. and Rosenberg, R.D. (1992) Isolation of a src homology 2-containing tyrosine phosphatase. Proc. Natl Acad. Sci. USA, 89, 1123-1127.
42. Quelle, F.W., Sato, N., Witthuhn, B.A., Inhorn, R.C., Eder, M., Miyajima, A., Griffin, J.D. and Ihle, J.N. (1994) JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony stimulating factor, and its activation requires the membrane-proximal region. Mol. Cell Biol., 14, 4335-4341.
43. Rui, H., Djeu, J.Y., Evans, G.A., Kelly, P.A. and Farrar, W.L. (1992) Prolactin receptor triggering. Evidence for rapid tyrosine kinase activation. J. Biol. Chem., 267, 24076-24081.
44. Rui, H., Kirken, R.A. and Farrar, W.L. (1994) Activation of receptor associated tyrosine kinase Jak2 by prolactin. J. Biol. Chem., 269, 5364-5368.
45. Shen, S.-H., Bastien, L., Posner, B.I. and Chretien, P. (1991) A protein-tyrosine phosphatase with sequence similarity to the SH2 domains of protein-tyrosine kinases. Nature (Lond.), 352, 736-739.
46. Shirota, M., Banville, D., Ali, S., Jolicoeur, C., Boutin, J.M., Edery, M., Djiane, J. and Kelly, P.A. (1990) Expression of two forms of prolactin receptor in rat ovary and liver. Mol. Endocrinol., 4, 1136-1143.
47. Shuai, K., Ziemieck, A., Wilks, A.F., Harpur, A.G., Sadowski, H.B., Gilman, M.Z. and Darnell, J.E. (1993) Polypeptide signaling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature, 366, 580-583.
48. Silvennoinen, O., Witthuhn, B.A., Quelle, F.W., Cleveland, J.L., Yi, T. and Ihle, J.N. (1993) Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. Proc. Natl Acad. Sci USA, 90, 8429-8433.
49. Sotiropoulos, A., Perrot-Applanat, M., Dinerstein, H., Pallier, A., Postel-Vinay, M.C., Finidori, J. and Kelly, P.A. (1994) Distinct cytoplasmic regions of the growth hormone receptor are required for activation of JAK2, mitogen-activated protein kinase, and transcription Endocrinology, 135, 1292-1298.
50. Stein-Gerlach, M., Kharitonenkov, A., Vogel, W., Ali, S. and Ullrich, A. (1995) Protein tyrosine phosphatase 1D modulates its own state of tyrosine phosphorylation. J. Biol. Chem., 270, 24635-24637.
51. Sugimoto, S., Wandless, T.J., Shoelson, S.E., Neel, B.G. and Walsh, C.T. (1994) Activation of the SH2-containing protein tyrosine phosphatase. SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1. J. Biol. Chem., 269, 13614-13622
52. Tauchi, T., Feng, G.S., Marshall, M.S., Shen, R., Mantel, C., Pawson, T. and Broxmeyer, H.E. (1994) The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells. J. Biol. Chem., 269, 25206-25211.
53. Tauchi, T., Feng, G.-S., Shen, R., Hoatlin, M., Bagby, G.C., Jr, Kabat, D., Lu, L. and Broxmeyer, H.E. (1995) Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways. J. Biol Chem., 270, 5631-5635.
54. VanderKuur, J.A., Wang, X., Zhang, L., Campbell, G.S., Allevato, G., Billestrup, N., Norstedt, G. and Carter-Su, C. (1994) Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase. J Biol. Chem., 269, 21709-21717.
55. Vogel, W., Lammers, R., Huang, J. and Ullrich, A. (1993) Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science, 259, 1611-1614.
56. Wakao, H., Gouilleux, F. and Groner, B. (1994) Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J., 13, 2182-2191.
57. Welham, M.J., Dechert, U., Leslie, K.B., Jirik, F. and Schrader, J.W. (1994) Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase. J Biol. Chem., 269, 23764-23768.
58. Xiao, S., Rose, D.W., Sasaoka, T., Maegawa, H., Burke, T.R., Jr, Roller, P.P., Shoelson, S.E. and Olefsky, J.M. (1994) Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J. Biol Chem., 269, 21244-21248.
59. Yamauchi, K., Milarski, K.L., Saltiel, A.R. and Pessin, J.E. (1995) Protein-tyrosine phosphatase SHPTP2 is a required effector for insulin downstream signaling. Proc. Natl Acad. Sci. USA, 92, 664-668.
60. Yi, T., Cleveland, J.L. and Ihle, J.N. (1992) Protein tyrosine phosphatase containing SH2 domain, characterization, preferential expression in hematopoietic cells and localization to human chromosome 12p12p-13. Mol Cell. Biol., 12, 836-846.
61. Yi, T., Mui, A.L.-E. Krystal, G. and Ihle, J.N. (1993) Hematopoietic cell phosphatase associates with the interleukin-2 (1L-3) receptor β-chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol. Cell. Biol., 13, 7577-7586.