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Volumn 144, Issue 12, 2003, Pages 5300-5307

Inhibition of Prolactin (PRL)-Induced Proliferative Signals in Breast Cancer Cells by a Molecular Mimic of Phosphorylated PRL, S179D-PRL

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PROLACTIN; PROLACTIN RECEPTOR; SERINE; STAT5 PROTEIN;

EID: 0345257112     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0826     Document Type: Article
Times cited : (45)

References (46)
  • 1
    • 0032460226 scopus 로고    scopus 로고
    • Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice
    • Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA 1998 Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 19:225-268
    • (1998) Endocr Rev , vol.19 , pp. 225-268
    • Bole-Feysot, C.1    Goffin, V.2    Edery, M.3    Binart, N.4    Kelly, P.A.5
  • 4
    • 0002571747 scopus 로고    scopus 로고
    • Prolactin in human breast cancer development
    • Ethier SP, ed. Totowa, NJ: Humana Press
    • Vonderhaar BK 2000 Prolactin in human breast cancer development. In: Ethier SP, ed. Endocrine oncology. Totowa, NJ: Humana Press; 101-120
    • (2000) Endocrine Oncology , pp. 101-120
    • Vonderhaar, B.K.1
  • 6
    • 0017615463 scopus 로고
    • Prolactin and murine mammary tumorigenesis: A review
    • Welsch CW, Nagasawa H 1977 Prolactin and murine mammary tumorigenesis: a review. Cancer Res 37:951-963
    • (1977) Cancer Res , vol.37 , pp. 951-963
    • Welsch, C.W.1    Nagasawa, H.2
  • 7
    • 0007720981 scopus 로고
    • Prolactin and the induction of mammary tumors in mice
    • Boot LM, Muhlbock O, Ropcke G 1962 Prolactin and the induction of mammary tumors in mice. Gen Comp Endocrinol 2:601-603
    • (1962) Gen Comp Endocrinol , vol.2 , pp. 601-603
    • Boot, L.M.1    Muhlbock, O.2    Ropcke, G.3
  • 8
    • 0034696342 scopus 로고    scopus 로고
    • Prolactin gene-disruption arrests mammary gland development and retards T-antigen-induced tumor growth
    • Vomachka AJ, Pratt SL, Lockefeer JA, Horseman ND 2000 Prolactin gene-disruption arrests mammary gland development and retards T-antigen-induced tumor growth. Oncogene 19:1077-1084
    • (2000) Oncogene , vol.19 , pp. 1077-1084
    • Vomachka, A.J.1    Pratt, S.L.2    Lockefeer, J.A.3    Horseman, N.D.4
  • 9
    • 0031454715 scopus 로고    scopus 로고
    • Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice
    • Wennbo H, Gebre-Medhin M, Gritli-Linde A, Ohlsson C, Isaksson OGP, Törnell J 1997 Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice. J Clin Invest 100:2744-2751
    • (1997) J Clin Invest , vol.100 , pp. 2744-2751
    • Wennbo, H.1    Gebre-Medhin, M.2    Gritli-Linde, A.3    Ohlsson, C.4    Isaksson, O.G.P.5    Törnell, J.6
  • 16
    • 0029035666 scopus 로고
    • Structural variants of prolactin: Occurrence and physiological significance
    • Sinha YN 1995 Structural variants of prolactin: occurrence and physiological significance. Endocr Rev 16:354-369
    • (1995) Endocr Rev , vol.16 , pp. 354-369
    • Sinha, Y.N.1
  • 17
    • 0002525191 scopus 로고    scopus 로고
    • Structure-function relationships in prolactin
    • Horseman ND, ed. Boston: Kluwer Academic Press
    • Lorenson MY, Walker AM 2001 Structure-function relationships in prolactin. In: Horseman ND, ed. Prolactin. Boston: Kluwer Academic Press; 189-217
    • (2001) Prolactin , pp. 189-217
    • Lorenson, M.Y.1    Walker, A.M.2
  • 18
    • 0029162339 scopus 로고
    • Biological activity of phosphorylated and dephosphorylated bovine prolactin
    • Wicks JR, Brooks CL 1995 Biological activity of phosphorylated and dephosphorylated bovine prolactin. Mol Cell Endocrinol 112:223-229
    • (1995) Mol Cell Endocrinol , vol.112 , pp. 223-229
    • Wicks, J.R.1    Brooks, C.L.2
  • 19
    • 0027453895 scopus 로고
    • Secretion of specific nonphosphorylated and phosphorylated rat prolactin isoforms at different stages of the estrous cycle
    • Ho TWC, Leong FS, Olaso CH, Walker AM 1993 Secretion of specific nonphosphorylated and phosphorylated rat prolactin isoforms at different stages of the estrous cycle. Neuroendocrinology 58:160-165
    • (1993) Neuroendocrinology , vol.58 , pp. 160-165
    • Ho, T.W.C.1    Leong, F.S.2    Olaso, C.H.3    Walker, A.M.4
  • 21
    • 0030028521 scopus 로고    scopus 로고
    • Identification of the major site of rat prolactin phosphorylation as serine 177
    • Wang YF, Liu JW, Mamidi M, Walker AM 1996 Identification of the major site of rat prolactin phosphorylation as serine 177. J Biol Chem 271:2462-2469
    • (1996) J Biol Chem , vol.271 , pp. 2462-2469
    • Wang, Y.F.1    Liu, J.W.2    Mamidi, M.3    Walker, A.M.4
  • 22
    • 0031790107 scopus 로고    scopus 로고
    • Development of recombinant human prolactin receptor antagonists by molecular mimicry of the phosphorylated hormone
    • Chen TJ, Kuo CB, Tsai KF, Liu JW, Chen DY, Walker AM 1998 Development of recombinant human prolactin receptor antagonists by molecular mimicry of the phosphorylated hormone. Endocrinology 139:609-616
    • (1998) Endocrinology , vol.139 , pp. 609-616
    • Chen, T.J.1    Kuo, C.B.2    Tsai, K.F.3    Liu, J.W.4    Chen, D.Y.5    Walker, A.M.6
  • 23
    • 0033303811 scopus 로고    scopus 로고
    • Dissociation of Janus kinase 2 and signal transducer and activator of transcription 5 activation after treatment of nb2 cells with a molecular mimic of phosphorylated prolactin
    • Coss D, Kuo CB, Yang L, Ingleton P, Luben R, Walker AM 1999 Dissociation of Janus kinase 2 and signal transducer and activator of transcription 5 activation after treatment of nb2 cells with a molecular mimic of phosphorylated prolactin. Endocrinology 140:5087-5094
    • (1999) Endocrinology , vol.140 , pp. 5087-5094
    • Coss, D.1    Kuo, C.B.2    Yang, L.3    Ingleton, P.4    Luben, R.5    Walker, A.M.6
  • 25
    • 0036037290 scopus 로고    scopus 로고
    • Pseudophosphorylated prolactin (S179D PRL) inhibits growth and promotes β-casein gene expression in the rat mammary gland
    • Kuo CB, Wu W, Xu X, Yang L, Chen C, Coss D, Birdsall B, Nasseri D, Walker AM 2002 Pseudophosphorylated prolactin (S179D PRL) inhibits growth and promotes β-casein gene expression in the rat mammary gland. Cell Tissue Res 309:429-437
    • (2002) Cell Tissue Res , vol.309 , pp. 429-437
    • Kuo, C.B.1    Wu, W.2    Xu, X.3    Yang, L.4    Chen, C.5    Coss, D.6    Birdsall, B.7    Nasseri, D.8    Walker, A.M.9
  • 27
    • 0013372232 scopus 로고    scopus 로고
    • Differential modulation of the expression of the long and short form of the PRL receptor and β-casein by unmodified PRL and a molecular mimic of phosphorylated PRL suggests that the short form of the receptor does not act as a dominant negative for signalling resulting in β-casein expression
    • Denver, CO, Abstract
    • Wu W, Xu X, Walker AM, Differential modulation of the expression of the long and short form of the PRL receptor and β-casein by unmodified PRL and a molecular mimic of phosphorylated PRL suggests that the short form of the receptor does not act as a dominant negative for signalling resulting in β-casein expression. Program of the 83rd Annual Meeting of The Endocrine Society, Denver, CO, 2002, p 340 (Abstract)
    • (2002) Program of the 83rd Annual Meeting of the Endocrine Society , pp. 340
    • Wu, W.1    Xu, X.2    Walker, A.M.3
  • 28
    • 0038408583 scopus 로고    scopus 로고
    • Different biological effects of unmodified PRL and a molecular mimic of phosphorylated prolactin involve different signaling pathways
    • Wu W, Coss D, Sorenson, MY, Kuo B, Xu X, Walker AM 2003 Different biological effects of unmodified PRL and a molecular mimic of phosphorylated prolactin involve different signaling pathways. Biochemistry 42:7561-7570
    • (2003) Biochemistry , vol.42 , pp. 7561-7570
    • Wu, W.1    Coss, D.2    Sorenson, M.Y.3    Kuo, B.4    Xu, X.5    Walker, A.M.6
  • 29
    • 0036140024 scopus 로고    scopus 로고
    • Prolactin modulates cell cycle regulators in mammary tumor epithelial cells
    • Schroeder MD, Symowicz J, Schuler LA 2002 Prolactin modulates cell cycle regulators in mammary tumor epithelial cells. Mol Endocrinol 16:45-57
    • (2002) Mol Endocrinol , vol.16 , pp. 45-57
    • Schroeder, M.D.1    Symowicz, J.2    Schuler, L.A.3
  • 30
    • 0036214521 scopus 로고    scopus 로고
    • Prolactin activates the cyclin D1 promoter via the JAK2-STAT pathway
    • Brockman JL, Schroeder MD, Schuler LA 2002 Prolactin activates the cyclin D1 promoter via the JAK2-STAT pathway. Mol Endocrinol 16:774-784
    • (2002) Mol Endocrinol , vol.16 , pp. 774-784
    • Brockman, J.L.1    Schroeder, M.D.2    Schuler, L.A.3
  • 31
    • 0035946511 scopus 로고    scopus 로고
    • Dysregulation of signal transducers and activators of transcription 1, 3, and 5 and prolactin receptors by overexpression of mammary TGFα
    • Schroeder MD, Rose-Hellekant T, Sandgren EP, Schuler LA 2001 Dysregulation of signal transducers and activators of transcription 1, 3, and 5 and prolactin receptors by overexpression of mammary TGFα. Mol Cell Endocrinol 175:173-183
    • (2001) Mol Cell Endocrinol , vol.175 , pp. 173-183
    • Schroeder, M.D.1    Rose-Hellekant, T.2    Sandgren, E.P.3    Schuler, L.A.4
  • 32
    • 0033544961 scopus 로고    scopus 로고
    • Functional characterization of the intermediate isoform of the human prolactin receptor
    • Kline JB, Roehrs H, Clevenger CV 1999 Functional characterization of the intermediate isoform of the human prolactin receptor. J Biol Chem 274:35461-35468
    • (1999) J Biol Chem , vol.274 , pp. 35461-35468
    • Kline, J.B.1    Roehrs, H.2    Clevenger, C.V.3
  • 33
    • 0010564030 scopus 로고
    • Construction of plasmids that express E. coli β-galactosidase in mammalian cells
    • MacGregor GR, Caskey CT 1989 Construction of plasmids that express E. coli β-galactosidase in mammalian cells. Nucleic Acids Res 17:2365
    • (1989) Nucleic Acids Res , vol.17 , pp. 2365
    • MacGregor, G.R.1    Caskey, C.T.2
  • 34
    • 0030749427 scopus 로고    scopus 로고
    • Expression of the prolactin gene in normal and neoplastic human breast tissues and human breast cell lines: Promoter usage and alternative mRNA splicing
    • Shaw-Bruha CM, Pirrucello SJ, Shull JD 1997 Expression of the prolactin gene in normal and neoplastic human breast tissues and human breast cell lines: promoter usage and alternative mRNA splicing. Br Can Res Treat 44:243-253
    • (1997) Br Can Res Treat , vol.44 , pp. 243-253
    • Shaw-Bruha, C.M.1    Pirrucello, S.J.2    Shull, J.D.3
  • 35
    • 0029012232 scopus 로고
    • Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines
    • Fuh G, Wells JA 1995 Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines. J Biol Chem 270:13133-13137
    • (1995) J Biol Chem , vol.270 , pp. 13133-13137
    • Fuh, G.1    Wells, J.A.2
  • 37
    • 0027546915 scopus 로고
    • Mechanisms of prolactin receptor regulation in mammary gland
    • Ormandy CJ, Sutherland RL 1993 Mechanisms of prolactin receptor regulation in mammary gland. Mol Cell Endocrinol 91:C1-C6
    • (1993) Mol Cell Endocrinol , vol.91
    • Ormandy, C.J.1    Sutherland, R.L.2
  • 38
    • 0031958292 scopus 로고    scopus 로고
    • Prolactin receptor gene diversity: Structure and regulation
    • Hu ZZ, Zhuang L, Dufau ML 1998 Prolactin receptor gene diversity: Structure and regulation. Trends Endocrinol Metab 9:94-102
    • (1998) Trends Endocrinol Metab , vol.9 , pp. 94-102
    • Hu, Z.Z.1    Zhuang, L.2    Dufau, M.L.3
  • 40
    • 0030451788 scopus 로고    scopus 로고
    • Extrapituitary prolactin: Distribution, regulation, functions, and clinical aspects
    • Ben-Jonathan N, Mershon JL, Allen DL, Steinmetz RW 1996 Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects. Endocr Rev 17:639-669
    • (1996) Endocr Rev , vol.17 , pp. 639-669
    • Ben-Jonathan, N.1    Mershon, J.L.2    Allen, D.L.3    Steinmetz, R.W.4
  • 41
    • 0034014355 scopus 로고    scopus 로고
    • Inhibition of mitogen-actived protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis
    • Lobenhofer E, Huper G, Iglehart JD, Marks JR 2000 Inhibition of mitogen-actived protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis. Cell Growth Differ 11:99-110
    • (2000) Cell Growth Differ , vol.11 , pp. 99-110
    • Lobenhofer, E.1    Huper, G.2    Iglehart, J.D.3    Marks, J.R.4
  • 42
    • 0037019186 scopus 로고    scopus 로고
    • Distinct roles for phosphoinositide 3-kinase, mitogen-activated protein kinase and p38 MAPK in mediating cell cycle progression of breast cancer cells
    • Neve RM, Holbro T, Hynes NE 2002 Distinct roles for phosphoinositide 3-kinase, mitogen-activated protein kinase and p38 MAPK in mediating cell cycle progression of breast cancer cells Oncogene 21:4567-4576
    • (2002) Oncogene , vol.21 , pp. 4567-4576
    • Neve, R.M.1    Holbro, T.2    Hynes, N.E.3
  • 43
    • 0033848878 scopus 로고    scopus 로고
    • Integrating the MAP kinase signal into the G1 phase cell cycle machinery
    • Roovers K, Assoian RK 2000 Integrating the MAP kinase signal into the G1 phase cell cycle machinery. Bioessays 22:818-826
    • (2000) Bioessays , vol.22 , pp. 818-826
    • Roovers, K.1    Assoian, R.K.2
  • 44
    • 0029972947 scopus 로고    scopus 로고
    • Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassay
    • Goffin V, Kinet S, Ferrag F, Binart N, Martial JA, Kelly PA 1996 Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassay. J Biol Chem 271:16573-16579
    • (1996) J Biol Chem , vol.271 , pp. 16573-16579
    • Goffin, V.1    Kinet, S.2    Ferrag, F.3    Binart, N.4    Martial, J.A.5    Kelly, P.A.6
  • 45
    • 0036794307 scopus 로고    scopus 로고
    • Characterization of a novel and functional human prolactin receptor isoform (δS1PRLr) containing only one extracellular fibronectin-like domain
    • Kline JB, Rycyzyn MA, Clevenger CV 2002 Characterization of a novel and functional human prolactin receptor isoform (δS1PRLr) containing only one extracellular fibronectin-like domain. Mol Endocrinol 16:2310-2322
    • (2002) Mol Endocrinol , vol.16 , pp. 2310-2322
    • Kline, J.B.1    Rycyzyn, M.A.2    Clevenger, C.V.3
  • 46
    • 0035798602 scopus 로고    scopus 로고
    • Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11
    • Hu Z-Z, Meng J, Dufau ML 2001 Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11. J Biol Chem 276:41086-41094
    • (2001) J Biol Chem , vol.276 , pp. 41086-41094
    • Hu, Z.-Z.1    Meng, J.2    Dufau, M.L.3


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