Discovery of histamine H3 receptor antagonistic property of simple imidazole-free derivatives: Preliminary pharmacological investigation

Pharmacological Research

Volumn 53, Issue 3, 2006, Pages 226-232

  Barocelli, Elisabetta ^a   Ballabeni, Vigilio ^a   Manenti, Veronica ^a   Flammini, Lisa ^a   Bertoni, Simona ^a   Morini, Giovanni ^a   Comini, Mara ^a   Impicciatore, Mariannina ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Binding study; Functional cAMP assay; Histamine H3 receptor; Non imidazole H3 antagonists; pKi pKB correlation

Indexed keywords

HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; IMIDAZOLE DERIVATIVE; PIPERIDINE DERIVATIVE; THIOPERAMIDE; ANTIHISTAMINIC AGENT;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR SENSITIVITY; ANIMAL; BRAIN CORTEX; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; ILEUM; METABOLISM; SMOOTH MUSCLE; STRUCTURE ACTIVITY RELATION; WISTAR RAT;

ANIMALS; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HISTAMINE ANTAGONISTS; ILEUM; MUSCLE, SMOOTH; PIPERIDINES; RATS; RATS, WISTAR; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 32644473667     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phrs.2005.11.004     Document Type: Article

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