Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous system

Pharmacology and Therapeutics

Volumn 103, Issue 1, 2004, Pages 1-20

  Witkin, J M ^a   Nelson, D L ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

4 (3 ((4 ((2R) 2aminopropanoyl) 1 piperazinyl)propoxy)phenyl)(cyclopropyl)methanone; A 304121; A 317920; Attention deficit hyperactivity disorder; Cognition; H3 receptors; Histamine; Review; Schizophrenia

Indexed keywords

1 (BENZO[B]THIEN 5 YL) 2 (2 DIETHYLAMINOETHOXY)ETHANOL; 2 (2 OXO 1 PYRROLIDINYL) N (5,6,7,8 TETRAHYDRO 2,3 DIMETHYLFURO[2,3 B]QUINOLIN 4 YL)ACETAMIDE; 2 METHYL 3 (2 PYRROLIDINYLMETHOXY)PYRIDINE; 6 QUINOXALINECARBOXYLIC ACID PIPERIDIDE; [2 [4 [3 [4 (CYCLOPROPYLCARBONYL)PHENOXY]PROPYL] 1 PIPERAZINYL] 1 METHYL 2 OXOETHYL] 2 FURAMIDE; A 317920; ANIRACETAM; ATORVASTATIN; CELECOXIB; CEP 1347; CIPROXIFAN; CLOBENPROPIT; DIZOCILPINE; DONEPEZIL; GALANTAMINE; HISTAMINE; HISTAMINE H2 RECEPTOR AGONIST; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; MEMANTINE; METRIFONATE; MONOAMINE; NEFIRACETAM; NIMODIPINE; PHENSERINE; RIVASTIGMINE; SCOPOLAMINE; TACRINE; THIOPERAMIDE; TRANLON; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZANEPEZIL; ANTIHISTAMINIC AGENT;

ALZHEIMER DISEASE; AROUSAL; ATTENTION; ATTENTION DEFICIT DISORDER; BEHAVIOR; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL TRIAL; COGNITION; COGNITIVE DEFECT; DATA ANALYSIS; DEPRESSION; DISEASE MODEL; DISEASE SEVERITY; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; DRUG SAFETY; DRUG SELECTIVITY; EPILEPSY; EXPERIMENTAL TEST; HEART ARRHYTHMIA; HUMAN; MEMORY; MENTAL PERFORMANCE; NERVE TRACT; NEUROANATOMY; NEUROBIOLOGY; NEUROCHEMISTRY; NEUROTRANSMISSION; NONHUMAN; OBESITY; PAIN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SCHIZOPHRENIA; SIDE EFFECT; SLEEP DISORDER; STRESS; SYNAPSE; TREATMENT INDICATION; WAKEFULNESS; ANIMAL; METABOLISM; PHYSIOLOGY;

ANIMALS; CENTRAL NERVOUS SYSTEM DISEASES; COGNITION DISORDERS; HISTAMINE; HISTAMINE ANTAGONISTS; HUMANS; RECEPTORS, HISTAMINE H3;

EID: 3042748136     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2004.05.001     Document Type: Review

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