[3H]-thioperamide as a radioligand for the histamine H3 receptor in rat cerebral cortex

British Journal of Pharmacology

Volumn 118, Issue 8, 1996, Pages 2045-2052

  Alves Rodrigues, Alexandra ^a   Leurs, Rob ^a   Wu, Tin Seng ^a   Prell, George D ^b   Foged, Christian ^c   Timmerman, Henk ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c NOVO NORDISK A S   (Denmark)

Author keywords

Cytochrome P450 isoenzymes; H3 antagonist; Histamine H3 receptor; Rat cerebral cortex; Stereoselectivity; 3H thioperamide

Indexed keywords

ALPHA METHYLHISTAMINE; BURIMAMIDE; CYTOCHROME P450; ENZYME INHIBITOR; HALOPERIDOL; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; IMETIT; IMMEPIP; IODOPHENPROPIT; IODOPROXYFAN; ONDANSETRON; RADIOLIGAND; THIOPERAMIDE; UNCLASSIFIED DRUG; ANTIHISTAMINIC AGENT; DRUG DERIVATIVE; HISTAMINE RECEPTOR; IMIDAZOLE DERIVATIVE; PIPERIDINE DERIVATIVE; THIOUREA DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG BINDING; INCUBATION TIME; LIVER MICROSOME; MALE; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; TEMPERATURE; ANIMAL; DOSE RESPONSE; DRUG EFFECT; RADIOASSAY; WISTAR RAT;

ANIMALS; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE ANTAGONISTS; IMIDAZOLES; ISOTHIURONIUM; MALE; PIPERIDINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, HISTAMINE;

EID: 0029658135     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15642.x     Document Type: Article

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