메뉴 건너뛰기




Volumn , Issue 64, 2003, Pages 1-16

Therapeutic implications of constitutive activity of receptors: The example of the histamine H3 receptor

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE RECEPTOR BLOCKING AGENT; ANTIHISTAMINIC AGENT; CALCIMYCIN; CIMETIDINE; CIPROXIFAN; CLOZAPINE; DOPAMINE RECEPTOR STIMULATING AGENT; ETHER DERIVATIVE; FAMOTIDINE; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HALOPERIDOL; HISTAMINE; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR; IMETIT; MEPYRAMINE; METHAMPHETAMINE; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; NEUROLEPTIC AGENT; TACRINE; THIOPERAMIDE; YOHIMBINE;

EID: 0043245853     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6020-6_1     Document Type: Conference Paper
Times cited : (36)

References (47)
  • 8
    • 0032938367 scopus 로고    scopus 로고
    • 4 receptor splice variants show marked constitutive activity: Role of the C-terminal intracellular domain
    • 4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain. Mol Pharmacol 55: 910-920
    • (1999) Mol Pharmacol , vol.55 , pp. 910-920
    • Claeysen, S.1    Sebben, M.2    Becamel, C.3    Bockaert, J.4    Dumuis, A.5
  • 9
    • 0028363255 scopus 로고
    • 3 receptor antagonist, attenuates stimulant-induced locomotor activity in the mouse
    • 3 receptor antagonist, attenuates stimulant-induced locomotor activity in the mouse. Eur J Pharmacol 259: 107-114
    • (1994) Eur J Pharmacol , vol.259 , pp. 107-114
    • Clapham, J.1    Kilpatrick, G.J.2
  • 10
    • 0028809293 scopus 로고
    • 3-receptors in rat cerebral cortical membranes
    • 3-receptors in rat cerebral cortical membranes. Br J Pharmacol 114: 357-362
    • (1995) Br J Pharmacol , vol.114 , pp. 357-362
    • Clark, E.A.1    Hill, S.J.2
  • 11
    • 0029670665 scopus 로고    scopus 로고
    • 35S]GTP gamma[S] binding to pertussis toxin
    • 35S]GTP gamma[S] binding to pertussis toxin. Eur J Pharmacol 296: 223-225
    • (1996) Eur J Pharmacol , vol.296 , pp. 223-225
    • Clark, E.A.1    Hill, S.J.2
  • 12
    • 0001169515 scopus 로고
    • Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins
    • Costa T, Herz A (1989) Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. Proc Natl Acad Sci USA 86: 7321-7325
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7321-7325
    • Costa, T.1    Herz, A.2
  • 13
    • 0026608113 scopus 로고
    • Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: Thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand
    • Costa T, Ogino Y, Munson PJ, Onaran O, Rodbard D (1992) Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand. Mol Pharmacol 41: 549-560
    • (1992) Mol Pharmacol , vol.41 , pp. 549-560
    • Costa, T.1    Ogino, Y.2    Munson, P.J.3    Onaran, O.4    Rodbard, D.5
  • 14
    • 0034016295 scopus 로고    scopus 로고
    • Inverse agonism at G protein-coupled receptors: (Patho)physiological relevance and implications for drug discovery
    • de Ligt RAF, Kourounakis AP, Ijzerman AP (2000) Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery. Br J Pharmacol 130: 1-12
    • (2000) Br J Pharmacol , vol.130 , pp. 1-12
    • De Ligt, R.A.F.1    Kourounakis, A.P.2    Ijzerman, A.P.3
  • 15
  • 17
    • 0030434807 scopus 로고    scopus 로고
    • Effects of dopamine antagonists on neuronal histamine release in the striatum of rats subjected to acute and chronic treatments with methamphetamine
    • Ito C, Onodera K, Sakurai E, Sato M, Watanabe T (1996) Effects of dopamine antagonists on neuronal histamine release in the striatum of rats subjected to acute and chronic treatments with methamphetamine. J Pharmacol Exp Ther 279: 271-276
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 271-276
    • Ito, C.1    Onodera, K.2    Sakurai, E.3    Sato, M.4    Watanabe, T.5
  • 20
    • 0028883925 scopus 로고
    • Cholinergic nucleus basilis neurons are excited by histamine in vitro
    • Khateb A, Fort P, Pegna A, Jones BE, Muhlethaler M (1995) Cholinergic nucleus basilis neurons are excited by histamine in vitro. Neuroscience 69: 495-506
    • (1995) Neuroscience , vol.69 , pp. 495-506
    • Khateb, A.1    Fort, P.2    Pegna, A.3    Jones, B.E.4    Muhlethaler, M.5
  • 21
    • 0031724514 scopus 로고    scopus 로고
    • 3 receptor-dependent G protein activation in rat brain tissue sections
    • 3 receptor-dependent G protein activation in rat brain tissue sections. J Neurochem 71: 808-816
    • (1998) J Neurochem , vol.71 , pp. 808-816
    • Laitinen, J.T.1    Jokinen, M.2
  • 22
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
    • Lefkowitz RJ, Cotecchia S, Samama P, Costa T (1993) Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol Sci 14: 303-307
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 303-307
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 23
    • 0031794526 scopus 로고    scopus 로고
    • Agonist-independent regulation of constitutively active G-protein-coupled receptors
    • Leurs R, Smit MJ, Alewijnse AE, Timmerman H (1998) Agonist-independent regulation of constitutively active G-protein-coupled receptors. Trends Biochem Sci 23: 418-422
    • (1998) Trends Biochem Sci , vol.23 , pp. 418-422
    • Leurs, R.1    Smit, M.J.2    Alewijnse, A.E.3    Timmerman, H.4
  • 27
    • 0027055971 scopus 로고
    • Modulation of cardiac cyclic AMP metabolism by adenosine receptor agonists and antagonists
    • Ma H, Green RD (1992) Modulation of cardiac cyclic AMP metabolism by adenosine receptor agonists and antagonists. Mol Pharmacol 42: 831-837
    • (1992) Mol Pharmacol , vol.42 , pp. 831-837
    • Ma, H.1    Green, R.D.2
  • 28
    • 0031465316 scopus 로고    scopus 로고
    • Inverse agonism and the regulation of receptor number
    • Milligan G, Bond R (1997) Inverse agonism and the regulation of receptor number. Trends Pharmacol Sci 18: 468-474
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 468-474
    • Milligan, G.1    Bond, R.2
  • 29
    • 0028861330 scopus 로고
    • Inverse agonism: Pharmacological curiosity or potential therapeutic strategy?
    • Milligan G, Bond R, Lee M (1995) Inverse agonism: pharmacological curiosity or potential therapeutic strategy? Trends Pharmacol Sci 16: 10-13
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 10-13
    • Milligan, G.1    Bond, R.2    Lee, M.3
  • 30
    • 0030574248 scopus 로고    scopus 로고
    • Inhibition of histamine versus acetylcholine metabolism as a mechanism of tacrine activity
    • Morisset S, Traiffort E, Schwartz JC (1996) Inhibition of histamine versus acetylcholine metabolism as a mechanism of tacrine activity. Eur J Pharmacol 315: R1-R2
    • (1996) Eur J Pharmacol , vol.315
    • Morisset, S.1    Traiffort, E.2    Schwartz, J.C.3
  • 39
    • 0031002114 scopus 로고    scopus 로고
    • Structure/function relationships of calcitonin analogues as agonists, antagonists, or inverse agonists in a constitutively activated receptor cell system
    • Pozvek G, Hilton JM, Quiza M, Houssami S, Sexton PM (1997) Structure/function relationships of calcitonin analogues as agonists, antagonists, or inverse agonists in a constitutively activated receptor cell system. Mol Pharmacol 51: 658-665
    • (1997) Mol Pharmacol , vol.51 , pp. 658-665
    • Pozvek, G.1    Hilton, J.M.2    Quiza, M.3    Houssami, S.4    Sexton, P.M.5
  • 40
    • 0028821071 scopus 로고
    • Histamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia: Their relationship to levels of other aminergic transmitters and ratings of symptoms
    • Prell GD, Green JP, Kaufmann CA, Khandelwal JK, Morrishow AM, Kirch DG, Linnoila M, Wyatt RJ (1995) Histamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia: their relationship to levels of other aminergic transmitters and ratings of symptoms. Schizophr Res 14: 93-104
    • (1995) Schizophr Res , vol.14 , pp. 93-104
    • Prell, G.D.1    Green, J.P.2    Kaufmann, C.A.3    Khandelwal, J.K.4    Morrishow, A.M.5    Kirch, D.G.6    Linnoila, M.7    Wyatt, R.J.8
  • 45
    • 0036468505 scopus 로고    scopus 로고
    • Mechanisms of inverse agonism at G-protein-coupled receptors
    • Strange P (2002) Mechanisms of inverse agonism at G-protein-coupled receptors. Trends Pharmacol Sci 23: 89-95
    • (2002) Trends Pharmacol Sci , vol.23 , pp. 89-95
    • Strange, P.1
  • 46
    • 0031456986 scopus 로고    scopus 로고
    • 35S]thio)triphosphate to NG108-15 cell membranes: Characterization of agonist and inverse agonist effects
    • 35S]thio)triphosphate to NG108-15 cell membranes: characterization of agonist and inverse agonist effects. J Pharmacol Exp Ther 283: 1276-1284
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1276-1284
    • Szekeres, P.G.1    Traynor, J.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.