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Volumn 285, Issue 3 29-3, 2003, Pages

IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation

Author keywords

Cytokine; Hypersecretion; Inflammation; MUC5AC

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCIAN BLUE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; INTERLEUKIN 13; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN; MUCIN 5AC; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

EID: 0043011579     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00089.2003     Document Type: Article
Times cited : (236)

References (44)
  • 2
    • 0035202405 scopus 로고    scopus 로고
    • Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha
    • Booth BW, Adler KB, Bonner JC, Tournier F, and Martin LD. Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha. Am J Respir Cell Mol Biol 25: 739-743, 2001.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 739-743
    • Booth, B.W.1    Adler, K.B.2    Bonner, J.C.3    Tournier, F.4    Martin, L.D.5
  • 3
    • 0028309683 scopus 로고
    • Human airway ion transport. Part one
    • Boucher RC. Human airway ion transport. Part one. Am J Respir Crit Care Med 150: 271-281, 1994.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 271-281
    • Boucher, R.C.1
  • 4
    • 0034974112 scopus 로고    scopus 로고
    • Regulation of 15-lipoxygenase isozymes and mucin secretion by cytokines in cultured normal human bronchial epithelial cells
    • Brown CD, Kilty I, Yeadon M, and Jenkinson S. Regulation of 15-lipoxygenase isozymes and mucin secretion by cytokines in cultured normal human bronchial epithelial cells. Inflamm Res 50: 321-326, 2001.
    • (2001) Inflamm Res , vol.50 , pp. 321-326
    • Brown, C.D.1    Kilty, I.2    Yeadon, M.3    Jenkinson, S.4
  • 5
    • 0034663958 scopus 로고    scopus 로고
    • The involvement of tyrosine kinases, cyclic AMP/protein kinase A, and p38 mitogen-activated protein kinase in IL-13-mediated arginase I induction in macrophages: Its implications in IL-13-inhibited nitric oxide production
    • Chang CI, Zoghi B, Liao JC, and Kuo L. The involvement of tyrosine kinases, cyclic AMP/protein kinase A, and p38 mitogen-activated protein kinase in IL-13-mediated arginase I induction in macrophages: its implications in IL-13-inhibited nitric oxide production. J Immunol 165: 2134-2141, 2000.
    • (2000) J Immunol , vol.165 , pp. 2134-2141
    • Chang, C.I.1    Zoghi, B.2    Liao, J.C.3    Kuo, L.4
  • 6
    • 0037592950 scopus 로고    scopus 로고
    • Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop
    • Chen Y, Thai P, Zhao YH, Ho YS, DeSouza MM, and Wu R. Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. J Biol Chem 278: 17036-17043, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 17036-17043
    • Chen, Y.1    Thai, P.2    Zhao, Y.H.3    Ho, Y.S.4    DeSouza, M.M.5    Wu, R.6
  • 7
    • 0018341940 scopus 로고
    • Hypersecretion of mucus glycoproteins in rat airways induced by tobacco smoke
    • Coles SJ, Levine LR, and Reid L. Hypersecretion of mucus glycoproteins in rat airways induced by tobacco smoke. Am J Pathol 94: 459-471, 1979.
    • (1979) Am J Pathol , vol.94 , pp. 459-471
    • Coles, S.J.1    Levine, L.R.2    Reid, L.3
  • 8
    • 0041629644 scopus 로고    scopus 로고
    • Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma
    • Corry DB and Kheradmand F. Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma. Am J Respir Med 1: 185, 2002,
    • (2002) Am J Respir Med , vol.1 , pp. 185
    • Corry, D.B.1    Kheradmand, F.2
  • 10
    • 0035845855 scopus 로고    scopus 로고
    • Induction of the IL-13 receptor alpha2-chain by IL-4 and IL-13 in human keratinocytes: Involvement of STAT 6, ERK and p38 MAPK pathways
    • David M, Ford D, Bertoglio J, Maizel AL, and Pierre J. Induction of the IL-13 receptor alpha2-chain by IL-4 and IL-13 in human keratinocytes: involvement of STAT6, ERK and p38 MAPK pathways. Oncogene 20: 6660-6668, 2001.
    • (2001) Oncogene , vol.20 , pp. 6660-6668
    • David, M.1    Ford, D.2    Bertoglio, J.3    Maizel, A.L.4    Pierre, J.5
  • 13
    • 0029685785 scopus 로고    scopus 로고
    • Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells
    • Gray TE, Guzman K, Davis CW, Abdullah LH, and Nettesheim P. Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells. Am J Respir Cell Mol Biol 14: 104-112, 1996.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 104-112
    • Gray, T.E.1    Guzman, K.2    Davis, C.W.3    Abdullah, L.H.4    Nettesheim, P.5
  • 15
    • 0037090417 scopus 로고    scopus 로고
    • Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain
    • Hirst SJ, Hallsworth MP, Peng Q, and Lee TH. Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain. Am J Respir Crit Care Med 165: 1161-1171, 2002.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1161-1171
    • Hirst, S.J.1    Hallsworth, M.P.2    Peng, Q.3    Lee, T.H.4
  • 16
    • 0033826756 scopus 로고    scopus 로고
    • Bronchial epithelium as a key regulator of airway allergen sensitisation and remodelling in asthma
    • Holgate ST, Lackie P, Wilson S, Roche W, and Davies D. Bronchial epithelium as a key regulator of airway allergen sensitisation and remodelling in asthma. Am J Respir Crit Care Med 162: S113-S117, 2000.
    • (2000) Am J Respir Crit Care Med , vol.162
    • Holgate, S.T.1    Lackie, P.2    Wilson, S.3    Roche, W.4    Davies, D.5
  • 17
    • 0032901154 scopus 로고    scopus 로고
    • Regulation of 15-lipoxygenase expression and mucus secretion by IL- 4 in human bronchial epithelial cells
    • Jayawiekreme SP, Gray T, Nettesheim P, and Eling T. Regulation of 15-lipoxygenase expression and mucus secretion by IL-4 in human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 276: L596-L603, 1999.
    • (1999) Am J Physiol Lung Cell Mol Physiol , vol.276
    • Jayawiekreme, S.P.1    Gray, T.2    Nettesheim, P.3    Eling, T.4
  • 20
    • 0041628462 scopus 로고    scopus 로고
    • Interleukin-1β induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ ERK, and PI 3K in human airway epithelial cells
    • Kim YD, Jeon JY, Woo HJ, Lee JC, Chung JH, Song SY, Yoon SK, and Baek SH. Interleukin-1β induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ ERK, and PI3K in human airway epithelial cells. J Korean Med Sci 17: 765-771, 2002.
    • (2002) J Korean Med Sci , vol.17 , pp. 765-771
    • Kim, Y.D.1    Jeon, J.Y.2    Woo, H.J.3    Lee, J.C.4    Chung, J.H.5    Song, S.Y.6    Yoon, S.K.7    Baek, S.H.8
  • 21
    • 0036194724 scopus 로고    scopus 로고
    • Mucus clearance as a primary innate defense mechanism for mammalian airways
    • Knowles MR and Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest 109: 571-577, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 571-577
    • Knowles, M.R.1    Boucher, R.C.2
  • 22
    • 0036845165 scopus 로고    scopus 로고
    • Interleukin-13 induces goblet cell differentiation in primary cell culture from guinea pig tracheal epithelium
    • Kondo M, Tamaoki J, Takeyama K, Nakata J, and Nagai A. Interleukin-13 induces goblet cell differentiation in primary cell culture from guinea pig tracheal epithelium. Am J Respir Cell Mol Biol 27: 536-541, 2002.
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 536-541
    • Kondo, M.1    Tamaoki, J.2    Takeyama, K.3    Nakata, J.4    Nagai, A.5
  • 23
    • 0032536837 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
    • Kuperman D, Schofield B, Wills-Karp M, and Grusby MJ. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med 187: 939-948, 1998.
    • (1998) J Exp Med , vol.187 , pp. 939-948
    • Kuperman, D.1    Schofield, B.2    Wills-Karp, M.3    Grusby, M.J.4
  • 28
    • 0032510596 scopus 로고    scopus 로고
    • Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells
    • Li JD, Feng W, Gallup M, Kim JH, Gum J, Kim Y, and Basbaum C. Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc Natl Acad Sci USA 95: 5718-5723, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5718-5723
    • Li, J.D.1    Feng, W.2    Gallup, M.3    Kim, J.H.4    Gum, J.5    Kim, Y.6    Basbaum, C.7
  • 29
    • 0037401805 scopus 로고    scopus 로고
    • Involvement of S6 kinase and p38 mitogen activated protein kinase pathways in strain-induced alignment and proliferation of bovine aortic smooth muscle cells
    • Li W, Chen Q, Mills I, and Sumpio BE. Involvement of S6 kinase and p38 mitogen activated protein kinase pathways in strain-induced alignment and proliferation of bovine aortic smooth muscle cells. J Cell Physiol 195: 202-209, 2003.
    • (2003) J Cell Physiol , vol.195 , pp. 202-209
    • Li, W.1    Chen, Q.2    Mills, I.3    Sumpio, B.E.4
  • 30
    • 0036181927 scopus 로고    scopus 로고
    • Native LDL induces proliferation of human vascular smooth muscle cells via redox-mediated activation of ERK 1/2 mitogen-activated protein kinases
    • Locher R, Brandes RP, Vetter W, and Barton M. Native LDL induces proliferation of human vascular smooth muscle cells via redox-mediated activation of ERK 1/2 mitogen-activated protein kinases. Hypertension 39: 645-650, 2002.
    • (2002) Hypertension , vol.39 , pp. 645-650
    • Locher, R.1    Brandes, R.P.2    Vetter, W.3    Barton, M.4
  • 31
    • 0030967811 scopus 로고    scopus 로고
    • Airway epithelium as an effector of inflammation: Molecular regulation of secondary mediators
    • Martin LD, Rochelle LG, Fischer BM, Krunkosy TM, and Adler KB. Airway epithelium as an effector of inflammation: molecular regulation of secondary mediators. Eur Respir J 10: 2139-2146, 1997.
    • (1997) Eur Respir J , vol.10 , pp. 2139-2146
    • Martin, L.D.1    Rochelle, L.G.2    Fischer, B.M.3    Krunkosy, T.M.4    Adler, K.B.5
  • 32
    • 0037215584 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase blocks activation of rat pancreatic stellate cells
    • Masamune A, Satoh M, Kikuta K, Sakai Y, Satoh A, and Shimosegawa T. Inhibition of p38 mitogen-activated protein kinase blocks activation of rat pancreatic stellate cells. J Pharmacol Exp Ther 304: 8-14, 2003.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 8-14
    • Masamune, A.1    Satoh, M.2    Kikuta, K.3    Sakai, Y.4    Satoh, A.5    Shimosegawa, T.6
  • 34
    • 0032009864 scopus 로고    scopus 로고
    • Structure of and signal transduction through interleukin-4 and interleukin-13 receptors
    • Murata T, Obiri NI, and Puri RK. Structure of and signal transduction through interleukin-4 and interleukin-13 receptors. Int J Mol Med 1: 551-557, 1998.
    • (1998) Int J Mol Med , vol.1 , pp. 551-557
    • Murata, T.1    Obiri, N.I.2    Puri, R.K.3
  • 35
    • 0035721544 scopus 로고    scopus 로고
    • Role of epidermal growth factor receptor activation in regulating mucin synthesis
    • Nadel JA. Role of epidermal growth factor receptor activation in regulating mucin synthesis. Respir Res 2: 85-89, 2001.
    • (2001) Respir Res , vol.2 , pp. 85-89
    • Nadel, J.A.1
  • 38
    • 0029930306 scopus 로고    scopus 로고
    • Hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium induced by endotoxin
    • Shimizu T, Takahashi Y, Kawaguchi S, and Sakakura Y. Hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium induced by endotoxin. Am J Respir Crit Care Med 153: 1412-1418, 1996.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1412-1418
    • Shimizu, T.1    Takahashi, Y.2    Kawaguchi, S.3    Sakakura, Y.4
  • 42
    • 0037059829 scopus 로고    scopus 로고
    • Novel cytoplasmic proteins of nontypeable Haemophilus influenzae up-regulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway
    • Wang B, Lim DJ, Han J, Kim YS, Basbaum CB, and Li JD. Novel cytoplasmic proteins of nontypeable Haemophilus influenzae up-regulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway. J Biol Chem 277: 949-957, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 949-957
    • Wang, B.1    Lim, D.J.2    Han, J.3    Kim, Y.S.4    Basbaum, C.B.5    Li, J.D.6
  • 44
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, and Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 103: 779-788, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8


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