The immunogenicity and protective efficacy of Mtb8.4/hIL-12 chimeric gene vaccine

Vaccine

Volumn 24, Issue 9, 2006, Pages 1315-1323

  Li, Hui ^a   Li, Rong ^b   Zhong, Sen ^a   Ren, Hong ^c   Zou, Yongsheng ^a   Chen, Xuanshi ^a   Shi, Xiaoling ^a   Wang, Mingyong ^a   Long, Han'an ^a   Luo, Yuebei ^d  

^a SOUTHWEST MEDICAL UNIVERSITY   (China)

^b Nanchang Blood Center   (China)

^c CHONGQING MEDICAL UNIVERSITY   (China)

^d SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Chimeric gene vaccine; Immune response; Mtb8.4 hIL 12; Protective efficacy; Tuberculosis

Indexed keywords

AGAR; CHIMERIC PROTEIN; CYTOKINE; DNA VACCINE; EOSIN; FORMALDEHYDE; HEMATOXYLIN; HUMAN INTERLEUKIN 12; INTERLEUKIN 4; PARAFFIN; PROTEIN MTB8.4; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL ACTIVITY; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DILUTION; DRUG EFFICACY; EUKARYOTE; EXPRESSION VECTOR; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; INFECTION PREVENTION; INOCULATION; ISOLATED LUNG; ISOLATED ORGAN; LUNG HOMOGENATE; LUNG INFLATION; MOLECULAR CLONING; MOUSE; MOUSE STRAIN; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROVOCATION TEST; SPLEEN; STAINING; TAIL; TEMPERATURE; TH1 CELL; TISSUE HOMOGENATE; TUBERCULOSIS; VACCINATION; VEIN;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; COLONY COUNT, MICROBIAL; CYTOKINES; CYTOTOXICITY TESTS, IMMUNOLOGIC; FEMALE; INTERLEUKIN-12; LUNG; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; SPLEEN; TUBERCULOSIS; TUBERCULOSIS VACCINES; VACCINES, DNA; VACCINES, SYNTHETIC;

EID: 32344441680     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.09.025     Document Type: Article

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