Molecular cloning and immunologic reactivity of a novel low molecular mass antigen of Mycobacterium tuberculosis

Journal of Immunology

Volumn 161, Issue 5, 1998, Pages 2356-2364

  Coler, Rhea N ^a,b   Skeiky, Yasir A W ^c   Vedvick, Thomas ^c   Bement, Teresa ^c   Ovendale, Pamela ^c   Campos Neto, Antonio ^b   Alderson, Mark R ^c   Reed, Steven G ^a,b,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b INFECTIOUS DISEASE RESEARCH INSTITUTE   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; MYCOBACTERIUM ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA LIBRARY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; MOLECULAR CLONING; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BASE SEQUENCE; BLOTTING, WESTERN; CLONING, MOLECULAR; CULTURE MEDIA; CYTOKINES; GENES, BACTERIAL; HUMANS; INJECTIONS, SUBCUTANEOUS; LEUKOCYTES, MONONUCLEAR; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MYCOBACTERIUM AVIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 0032167527     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Kochi, A. 1991. The global tuberculosis situation and the new control strategy of the World Health Organization. Tubercle 72:1.
2. Enarson, D. A., and J. F. Murray. 1996. Global epidemiology of tuberculosis. In Tuberculosis W. M. Rom and S. Garay. eds. Little, Brown and Co., Boston, pp. 57-75.
3. Hopeful, P. C. 1992. Impact of human immunodeficiency virus infection on the epidemiology, clinical features, management and control of tuberculosis. Clin. Infect. Dis. 18:540.
4. Colditz, G. A., T. F. Brewer, C. S. Berkey, M. E. Wilson, E. Burdick, H. V. Fineberg, and F. Mosteller. 1994. Efficacy of BCG vaccine in the prevention of tuberculosis. JAMA 271:698.
5. Fine, P. E. M., J. A. C. Sterne, J. M. Ponnighaus, and R. J. W. Rees. 1994. Delayed-type hypersensitivity, mycobacterial vaccines and protective immunity. Lancet 344:1245.
6. Fine, P. E. 1989. The BCG story: lessons from the past and implications for the future. Rev. Infect. Dis. 11(Suppl. 2):353.
7. Dubos, R. J., and C. H. Pierce. 1956. Differential characteristics in vitro and in vivo of several substrains of BCG. IV. Immunizing effectiveness. Am. Rev. Tuberc. 74:699.
8. Bloch, H., and W. Segal. 1955. Viability and multiplication of vaccines in immunization against tuberculosis. Am. Rev. Tuberc. Pulm. Dis. 71:228.
9. Orme, I. M. 1988. Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance, in mice inoculated with killed mycobacterial vaccines. Infect. Immun. 56:3310.
10. Laqueyrerie, A., P. Militzer, F. Romain, K. Eiglmeier, S. Cole, and G. Marchal. 1995. Cloning, sequencing, and expression of the apa gene coding for the Mycobacterium tuberculosis 45/47-kilodalton secreted antigen complex. Infect. Immun. 63:4003.
11. Crowle, A. J. 1988. Immunization against tuberculosis: what kind of vaccine? Infect. Immun. 56:2769.
12. Pal, P. G., and M. A. Horwitz. 1992. Immunization with extra-cellular proteins of Mycobacterium tuberculosis induces cell-mediated immune responses and substantial protective immunity in a guinea pig model of pulmonary tuberculosis. Infect. Immun. 60:4781.
13. Hubbard, R. D., C. M. Flory, and F. M. Collins. 1992. Immunization of mice with mycobacterial culture filtrate proteins. Clin. Exp. Immunol. 87:94.
14. Andersen, P. 1994. Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins. Infect. Immun. 62:2536.
15. Horwitz, M. A., B. E. Lee, B. J. Dillon, and G. Harth. 1995. Protective immunity against tuberculosis by vaccination with major extracellular proteins of Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 92:1530.
16. Roberts, A. D., M. G. Sonnenberg, D. J. Ordway, S. K. Furney, P. J. Brennan, J. T. Belisle, and I. M. Orme. 1995. Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate antigens of Mycobacterium tuberculosis. Immunology 85:502.
17. Haslov, K., A. Andersen, S. Nagai, A. Gottschau, T. Sorensen, and P. Andersen. 1995. Guinea pig cellular immune responses to proteins secreted by Mycobacterium tuberculosis. Infect. Immun. 63:804.
18. Orme, I. M. 1996. Immune responses in animal models. Curr. Top. Microbiol. Immunol. 215:181.
19. Leveton, C., S. Barnass, B. Champion, S. Lucas, B. De Souza, M. Nicol, D. Banerjee, and G. Rook. 1989. T-cell-mediated protection of mice against virulent Mycobacterium tuberculosis. Infect. Immun. 57:390.
20. Flynn, J. L., and B. R. Bloom. 1996. Role of T1 and T2 cytokines in the response to Mycobacterium tuberculosis. Ann N. Y. Acad. Sci. 795:137.
21. Flynn, J. L., J. Chan, K. J. Triebold, D. K. Dalton, T. A. Stewart, and B. R. Bloom. 1993. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249.
22. Andersen, P., A. B. Andersen, A. L. Sorensen, and A. Nagai. 1995. Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J. Immunol. 154:3359.
23. Newport, M. J., C. M. Huxley, S. Huston, C. M. Hawrylowicz, B. A. Oostra, R. Williamson, and M. Levin. 1996. A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection. N. Engl. J. Med. 335:1941.
24. Jouanguy, E., F. Altare, S. Lammhamedi, P. Revy, J. Emile, M. Newport, M. Levin, S. Blanche, E. Seboun, A. Fischer, and J. Casanova. 1996. Interferon-γ-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N. Engl. J. Med. 335:1956.
25. Andersen, P., D. Askgaard, A. Gottschau, J. Bennedsen, S. Nagai, and I. Heron. 1992. Identification of immunodominant antigens during infection with Mycobacterium tuberculosis. Scand. J. Immunol. 36:823.
26. Andersen, P., and I. Heron. 1993. Specificity of a protective immune response against Mycobacterium tuberculosis. Infect. Immun. 61:844.
27. Maniatis, T., E. F. Fritsch, and J. Sambrook, eds. 1989. Molecular Cloning: A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
28. Feinberg, A. P., and B. Vogelstein. 1984. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6.
29. Nagai, S., H. G. Wiker, M. Harboe, and M. Kinomoto. 1991. Isolation and partial characterization of major protein antigens in the culture fluid of Mycobacterium tuberculosis. Infect. Immun. 59:372.
30. Rambukkana, A., P. K. Das, J. D. Burggraaf, S. Yong, W. R. Faber, J. E. Thole, M. Harboe. 1992. Heterogeneity of monoclonal antibody-reactive epitopes on mycobacterial 30-kilodalton-region proteins and the secreted antigen 85 complex and demonstration of antigen 85B on the Mycobacterium leprae cell wall surface. Infect. Immun. 60:5172.
31. Yamaguchi, R., K. Matsuo, A. Yamakazi, C. Abe, S. Nagai, K. Terasaka, and T. Yamada. 1989. Cloning and characterization of the gene for immunogenic protein MPB64 of Mycobacterium bovis BCG. Infect. Immun. 57:283.
32. Oettinger, T., A. Holm, I. M. Mtoni, A. B. Andersen, and K. Haslov. 1995. Mapping of the delayed-type hypersensitivity-inducing epitope of secreted protein MPT64 from Mycobacterium tuberculosis. Infect. Immun. 63:4613.
33. Roche, P. W., N. Winter, J. A. Triccas, C. G. Feng, and W. J. Britton. 1996. Expression of Mycobacterium tuberculosis MPT64 in recombinant M. smegmatis: purification, immunogenicity and application to skin tests for tuberculosis. Clin. Exp. Immunol. 103:226.
34. Dobos, K. M., K. Swiderek, K. Khoo, P. J. Brennan, and J. T. Belisle. 1995. Evidence for glycosylation sites on the 45-kilodalton glycoprotein of Mycobacterium tuberculosis. Infect. Immun. 63:2846.
35. Espitia, C., R. Espinosa, R. Saavedra, R. Mancilla, F. Romain, A. Laqueyrerie, and C. Moreno. 1995. Antigenic and structural similarities between Mycobacterium tuberculosis 50-to 55-kilodalton and Mycobacterium bovis BCG 45-to 47-kilodalton antigens. Infect. Immun. 63:580.
36. J Zhang, M., Y. Lin, D. V. Iyer, J. Gong, J. Abrams, and P. Barnes. 1995. T-cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect. Immun. 63:3231.
37. Sorensen, A. L., S. Nagai, G. Houen, P. Andersen, and A. B. Andersen. 1995. Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect. Immun. 63:1710.
38. Yssel, H., R. de Waal Malefijt, M. G. Roncarolo, J. S. Abrams, R. Lahesmaa, H. Spits, and J. E. de Vries. 1992. IL-10 is produced by subsets of human CD4 T cell clones and peripheral blood T cells. J. Immunol. 149:2378.
39. Del Prete, G., M. De Carli, F. Almerigogna, M. G. Giudizi, R. Biagiotti, and S. Romagnani. 1993. Human IL-10 is produced by both type 1 helper (Th1) and type 2 (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J. Immunol. 150:353.
40. Flesch, I. E. A., and S. H. E. Kauffmann. 1990. Activation of tuberculostatic macrophage functions by γ-interferon, interleukin-4, and tumor necrosis factor. Infect. Immun. 58:2675.
41. Hirsch, C. S., J. J. Ellner, D. G. Russell, and E. A. Rich. 1994. Complement receptor-mediated uptake and tumor necrosis factor-γ-mediated growth inhibition of Mycobacterium tuberculosis by human alveolar macrophages. J. Immunol. 152:743.
42. Barnes, P. F., S. J. Fong, P. J. Brennan, P. E. Twomey, A. Mazumder, and R. L. Modlin. 1990. Local production of tumor necrosis factor and interferon-γ in tuberculous pleuritis. J. Immunol. 142:1114.
43. Cadranel, J., C. Philippe, J. Perez, B. Milleron, G. Akoun, R. Ardaillou, and L. Baud. 1990. In vitro production of tumor necrosis factor and prostaglandin E2 by peripheral blood mononuclear cells from tuberculosis patients. Clin. Exp. Immunol. 81:319.
44. Flynn, J. L., M. M. Goldstein, J. Chan, K. J. Triebold, K. Pfeffer, C. J. Lowenstein, R. Screiber, J. W. Mak, and B. R. Bloom. 1995. Tumor necrosis factor-γ is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2:561.
45. Del Prete, G. F., M. De Carli, C. Mastromauro, R. Biagiotti, D. Macchia, P. Falagiani, M. Ricci, and S. Romagnani. 1991. Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. J. Clin. Invest. 88:346.
46. Haanen, J. B. A. G., R. de Waal Malefijt, P. C. M. Res, E. M. Kraakman, T. H. M. Ottenhoff, R. R. P. de Vries, and H. Spits. 1991. Selection of a human T helper type 1-like T cell subset by mycobacteria. J. Exp. Med. 174:583.
47. + T-cell clones: heterogeneity in antigen recognition, cytokine production, and cytotoxicity for mononuclear phagocytes. Infect. Immun. 59:2737.
48. Barnes, P. F., J. S. Abrams, S. Lu, P. A. Sieling, T. H. Rea, and R. L. Modlin. 1993. Patterns of cytokine production by mycobacterium-reactive human T cell clones. Infect. Immun. 61:197.
49. Havlir, D. V., R. S. Wallis, W. H. Boom, T. M. Daniel, K. Chervenak, and J. J. Ellner. 1991. Human immune response to Mycobacterium tuberculosis antigens. Infect. Immun. 59:665.