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Volumn 12, Issue 4, 2000, Pages 442-447

DNA vaccines: A key for inducing long-term cellular immunity

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; PLASMID DNA;

EID: 0034086797     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(00)00118-7     Document Type: Review
Times cited : (230)

References (54)
  • 1
    • 0033228367 scopus 로고    scopus 로고
    • DNA vaccines: Basic mechanism and immune responses
    • Robinson H.L. DNA vaccines: basic mechanism and immune responses. Int J Mol Med. 4:1999;549-555.
    • (1999) Int J Mol Med , vol.4 , pp. 549-555
    • Robinson, H.L.1
  • 2
    • 0034046182 scopus 로고    scopus 로고
    • DNA vaccines: Immunology, application and optimisation
    • Gurunathan S., Klinman D., Seder R.A. DNA vaccines: immunology, application and optimisation. Annu Rev Immunol. 18:2000;927-974.
    • (2000) Annu Rev Immunol , vol.18 , pp. 927-974
    • Gurunathan, S.1    Klinman, D.2    Seder, R.A.3
  • 6
    • 0019398578 scopus 로고
    • DNA methylation and its possible biological roles
    • Razin A., Friedman J. DNA methylation and its possible biological roles. Prog Nucl Acid Res Mol Biol. 25:1981;33-52.
    • (1981) Prog Nucl Acid Res Mol Biol , vol.25 , pp. 33-52
    • Razin, A.1    Friedman, J.2
  • 7
    • 0030028722 scopus 로고    scopus 로고
    • Bacterial DNA induces murine interferon-γ production by stimulation of interleukin-12 and tumor necrosis factor-α
    • Halpern M.D., Kurlander R.J., Pisetsky D.S. Bacterial DNA induces murine interferon-γ production by stimulation of interleukin-12 and tumor necrosis factor-α Cell Immunol. 167:1996;72-78.
    • (1996) Cell Immunol , vol.167 , pp. 72-78
    • Halpern, M.D.1    Kurlander, R.J.2    Pisetsky, D.S.3
  • 8
    • 0029984358 scopus 로고    scopus 로고
    • CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon γ
    • Klinman D.M., Yi A.K., Beaucage S.L., Conover J., Krieg A.M. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon γ Proc Natl Acad Sci USA. 93:1996;2879-2883.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2879-2883
    • Klinman, D.M.1    Yi, A.K.2    Beaucage, S.L.3    Conover, J.4    Krieg, A.M.5
  • 9
    • 0029934754 scopus 로고    scopus 로고
    • Bacterial DNA induces NK cells to produce IFN-γ In vivo and increases the toxicity of lipopolysaccharides
    • Cowdery J.S., Chace J.H., Yi A.K., Krieg A.M. Bacterial DNA induces NK cells to produce IFN-γ in vivo and increases the toxicity of lipopolysaccharides. J Immunol. 156:1996;4570-4575.
    • (1996) J Immunol , vol.156 , pp. 4570-4575
    • Cowdery, J.S.1    Chace, J.H.2    Yi, A.K.3    Krieg, A.M.4
  • 10
    • 0031569601 scopus 로고    scopus 로고
    • Contribution of CpG motifs to the immunogenicity of DNA vaccines
    • Klinman D.M., Yamshchikov G., Ishigatsubo Y. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J Immunol. 158:1997;3635-3639.
    • (1997) J Immunol , vol.158 , pp. 3635-3639
    • Klinman, D.M.1    Yamshchikov, G.2    Ishigatsubo, Y.3
  • 11
    • 0032531036 scopus 로고    scopus 로고
    • Activation of cutaneous dendritic cells by CpG-containing oligodeoxy-nucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA
    • Jakob T., Walker P.S., Krieg A.M., Udey M.C., Vogel J.C. Activation of cutaneous dendritic cells by CpG-containing oligodeoxy-nucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA. J Immunol. 161:1998;3042-3049.
    • (1998) J Immunol , vol.161 , pp. 3042-3049
    • Jakob, T.1    Walker, P.S.2    Krieg, A.M.3    Udey, M.C.4    Vogel, J.C.5
  • 12
    • 0004582004 scopus 로고    scopus 로고
    • CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice
    • Brazolot Millan C.L., Weeratna R., Krieg A.M., Siegrist C.A., Davis H.L. CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice. Proc Natl Acad Sci USA. 95:1998;15553-15558.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15553-15558
    • Brazolot Millan, C.L.1    Weeratna, R.2    Krieg, A.M.3    Siegrist, C.A.4    Davis, H.L.5
  • 13
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
    • Davis H.L., Weeranta R., Waldschmidt T.J., Tygrett L., Schorr J., Krieg A.M. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J Immunol. 160:1998;870-876.
    • (1998) J Immunol , vol.160 , pp. 870-876
    • Davis, H.L.1    Weeranta, R.2    Waldschmidt, T.J.3    Tygrett, L.4    Schorr, J.5    Krieg, A.M.6
  • 14
    • 0031948647 scopus 로고    scopus 로고
    • Therapeutic applications of CpG-containing oligodeoxynucleotides
    • Klinman D.M. Therapeutic applications of CpG-containing oligodeoxynucleotides. Antisense Nucl Acid Drug Dev. 8:1998;181-184.
    • (1998) Antisense Nucl Acid Drug Dev , vol.8 , pp. 181-184
    • Klinman, D.M.1
  • 16
    • 0032476602 scopus 로고    scopus 로고
    • CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
    • Hacker H., Mischak H., Miethke T., Liptay S., Schmid R., Sparwasser T., Heeg K., Lipford G.B., Wagner H. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J. 17:1998;6230-6240.
    • (1998) EMBO J , vol.17 , pp. 6230-6240
    • Hacker, H.1    Mischak, H.2    Miethke, T.3    Liptay, S.4    Schmid, R.5    Sparwasser, T.6    Heeg, K.7    Lipford, G.B.8    Wagner, H.9
  • 17
  • 20
    • 0029789751 scopus 로고    scopus 로고
    • Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: Antigen presentation by non-muscle cells
    • Ulmer J.B., Deck R.R., Dewitt C.M., Donnhly J.I., Liu M.A. Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non-muscle cells. Immunology. 89:1996;59-67.
    • (1996) Immunology , vol.89 , pp. 59-67
    • Ulmer, J.B.1    Deck, R.R.2    Dewitt, C.M.3    Donnhly, J.I.4    Liu, M.A.5
  • 22
    • 0031569963 scopus 로고    scopus 로고
    • Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines
    • Iwasaki A., Stiernholm B.J., Chan A.K., Berinstein N.L., Barber B.H. Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines. J Immunol. 158:1997;4591-4601.
    • (1997) J Immunol , vol.158 , pp. 4591-4601
    • Iwasaki, A.1    Stiernholm, B.J.2    Chan, A.K.3    Berinstein, N.L.4    Barber, B.H.5
  • 23
    • 0031570044 scopus 로고    scopus 로고
    • Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations
    • Torres C.A., Iwasaki A., Barber B.H., Robinson H.L. Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations. J Immunol. 158:1997;4529-4532.
    • (1997) J Immunol , vol.158 , pp. 4529-4532
    • Torres, C.A.1    Iwasaki, A.2    Barber, B.H.3    Robinson, H.L.4
  • 24
    • 0025600919 scopus 로고
    • In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment
    • Yang N.S., Burkholder J., Roberts B., Martinell B., McCabe D. In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Proc Natl Acad Sci USA. 87:1990;9568-9572.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9568-9572
    • Yang, N.S.1    Burkholder, J.2    Roberts, B.3    Martinell, B.4    McCabe, D.5
  • 26
    • 0032032220 scopus 로고    scopus 로고
    • Contribution of cells at the site of DNA vaccination to the generation of antigen-specific immunity and memory
    • Klinman D.M., Sechler J.M., Conover J., Gu M., Rosenberg A.S. Contribution of cells at the site of DNA vaccination to the generation of antigen-specific immunity and memory. J Immunol. 160:1998;2388-2392.
    • (1998) J Immunol , vol.160 , pp. 2388-2392
    • Klinman, D.M.1    Sechler, J.M.2    Conover, J.3    Gu, M.4    Rosenberg, A.S.5
  • 27
    • 0032711215 scopus 로고    scopus 로고
    • In vivo priming by DNA injection occurs predominantly by antigen transfer
    • Corr M., von Damm A., Lee D.J., Tighe H. In vivo priming by DNA injection occurs predominantly by antigen transfer. J Immunol. 163:1999;4721-4727.
    • (1999) J Immunol , vol.163 , pp. 4721-4727
    • Corr, M.1    Von Damm, A.2    Lee, D.J.3    Tighe, H.4
  • 28
    • 0033521543 scopus 로고    scopus 로고
    • DNA vaccination: Transfection and activation of dendritic cells as key events for immunity
    • Elegant paper showing that dendritic cells are transfected in vivo. Also provides information about how long-term responses are generated
    • Akbari O., Panjwani N., Garcia S., Tascon R., Lowrie D., Stockinger B. DNA vaccination: transfection and activation of dendritic cells as key events for immunity. J Exp Med. 189:1999;169-178. Elegant paper showing that dendritic cells are transfected in vivo. Also provides information about how long-term responses are generated.
    • (1999) J Exp Med , vol.189 , pp. 169-178
    • Akbari, O.1    Panjwani, N.2    Garcia, S.3    Tascon, R.4    Lowrie, D.5    Stockinger, B.6
  • 29
    • 0029956512 scopus 로고    scopus 로고
    • Gene vaccination with naked plasmid DNA: Mechanism of CTL priming
    • Corr M., Lee D.J., Carson D.A., Tighe H. Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J Exp Med. 184:1996;1555-1560.
    • (1996) J Exp Med , vol.184 , pp. 1555-1560
    • Corr, M.1    Lee, D.J.2    Carson, D.A.3    Tighe, H.4
  • 30
    • 0031178797 scopus 로고    scopus 로고
    • The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites
    • Iwasaki A., Torres C.A., Ohashi P.S., Robinson H.L., Barber B.H. The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites. J Immunol. 159:1997;11-14.
    • (1997) J Immunol , vol.159 , pp. 11-14
    • Iwasaki, A.1    Torres, C.A.2    Ohashi, P.S.3    Robinson, H.L.4    Barber, B.H.5
  • 31
    • 0029737350 scopus 로고    scopus 로고
    • Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells
    • Doe B., Selby M., Barnett S., Baenziger J., Walker C.M. Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc Natl Acad Sci USA. 93:1996;8578-8583.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8578-8583
    • Doe, B.1    Selby, M.2    Barnett, S.3    Baenziger, J.4    Walker, C.M.5
  • 32
    • 0030698310 scopus 로고    scopus 로고
    • Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope
    • Casares S., Inaba K., Brumeanu T.D., Steinman R.M., Bona C.A. Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J Exp Med. 186:1997;1481-1486.
    • (1997) J Exp Med , vol.186 , pp. 1481-1486
    • Casares, S.1    Inaba, K.2    Brumeanu, T.D.3    Steinman, R.M.4    Bona, C.A.5
  • 34
    • 0029820526 scopus 로고    scopus 로고
    • DNA-based immunization by in vivo transfection of dendritic cells
    • Condon C., Watkins S.C., Celluzzi C.M., Thompson K., Falo L.D. Jr. DNA-based immunization by in vivo transfection of dendritic cells. Nat Med. 2:1996;1122-1128.
    • (1996) Nat Med , vol.2 , pp. 1122-1128
    • Condon, C.1    Watkins, S.C.2    Celluzzi, C.M.3    Thompson, K.4    Falo, L.D.5
  • 35
    • 0031570952 scopus 로고    scopus 로고
    • Dendritic cell subtypes in mouse lymphoid organs. Cross-correlation of surface markers, changes with incubation and differences among thymus, spleen and lymph nodes
    • Vremec D., Shortman K. Dendritic cell subtypes in mouse lymphoid organs. Cross-correlation of surface markers, changes with incubation and differences among thymus, spleen and lymph nodes. J Immunol. 159:1997;565-573.
    • (1997) J Immunol , vol.159 , pp. 565-573
    • Vremec, D.1    Shortman, K.2
  • 38
    • 0023267353 scopus 로고
    • Cytotoxic T lymphocytes against a soluble protein
    • Staerz U.D., Karasuyama H., Garner A.M. Cytotoxic T lymphocytes against a soluble protein. Nature. 329:1987;449-451.
    • (1987) Nature , vol.329 , pp. 449-451
    • Staerz, U.D.1    Karasuyama, H.2    Garner, A.M.3
  • 39
    • 0028052101 scopus 로고
    • Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules
    • Harding C.V., Song R. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules. J Immunol. 153:1994;4925-4933.
    • (1994) J Immunol , vol.153 , pp. 4925-4933
    • Harding, C.V.1    Song, R.2
  • 40
    • 0028998709 scopus 로고
    • Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity
    • Falo L.D. Jr., Kovacsovics-Bankowski M., Thompson K., Rock K.L. Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity. Nat Med. 1:1995;649-653.
    • (1995) Nat Med , vol.1 , pp. 649-653
    • Falo, L.D.1    Kovacsovics-Bankowski, M.2    Thompson, K.3    Rock, K.L.4
  • 41
    • 0027260585 scopus 로고
    • Heat shock protein 70-associated peptides elicit specific cancer immunity
    • Udono H., Srivastava P.K. Heat shock protein 70-associated peptides elicit specific cancer immunity. J Exp Med. 178:1993;1391-1396.
    • (1993) J Exp Med , vol.178 , pp. 1391-1396
    • Udono, H.1    Srivastava, P.K.2
  • 42
    • 0030820743 scopus 로고    scopus 로고
    • Priming of cytotoxic T lymphocytes by DNA vaccines: Requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes
    • Fu T.M., Ulmer J.B., Caulfield N.J., Deck R.R., Friedman A., Wang S., Liu X., Donnelly J.J., Liu M.A. Priming of cytotoxic T lymphocytes by DNA vaccines: requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes. Mol Med. 3:1997;362-371.
    • (1997) Mol Med , vol.3 , pp. 362-371
    • Fu, T.M.1    Ulmer, J.B.2    Caulfield, N.J.3    Deck, R.R.4    Friedman, A.5    Wang, S.6    Liu, X.7    Donnelly, J.J.8    Liu, M.A.9
  • 43
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Albert M.L., Sauter B., Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature. 392:1998;86-89.
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 44
    • 3543053363 scopus 로고    scopus 로고
    • Immature dendritic cells phagocytose apoptotic cells via αvβ5 and CD36, and cross-present antigens to cytotoxic lymphocytes
    • Albert M.L., Pearce S.F., Francisco L.M., Sauter B., Roy P., Silverstein R.L., Bhardwaj N. Immature dendritic cells phagocytose apoptotic cells via αVβ5 and CD36, and cross-present antigens to cytotoxic lymphocytes. J Exp Med. 188:1998;1359-1368.
    • (1998) J Exp Med , vol.188 , pp. 1359-1368
    • Albert, M.L.1    Pearce, S.F.2    Francisco, L.M.3    Sauter, B.4    Roy, P.5    Silverstein, R.L.6    Bhardwaj, N.7
  • 45
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • Recent paper defining the role of apoptosis and necrosis in the cross-priming and maturation, respectively, of dendritic cells
    • Sauter B., Albert M.L., Francisco L., Larsson M., Somersan S., Bhardwaj N. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med. 191:2000;423-433. Recent paper defining the role of apoptosis and necrosis in the cross-priming and maturation, respectively, of dendritic cells.
    • (2000) J Exp Med , vol.191 , pp. 423-433
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3    Larsson, M.4    Somersan, S.5    Bhardwaj, N.6
  • 47
    • 0032521881 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis
    • Zimmermann S., Egeter O., Hausmann S., Lipford G.B., Rocken M., Wagner H., Heeg K. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J Immunol. 160:1998;3627-3630.
    • (1998) J Immunol , vol.160 , pp. 3627-3630
    • Zimmermann, S.1    Egeter, O.2    Hausmann, S.3    Lipford, G.B.4    Rocken, M.5    Wagner, H.6    Heeg, K.7
  • 48
    • 0031757985 scopus 로고    scopus 로고
    • Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection
    • Gurunathan S., Prussin C., Sacks D.L., Seder R.A. Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection. Nat Med. 4:1998;1409-1415.
    • (1998) Nat Med , vol.4 , pp. 1409-1415
    • Gurunathan, S.1    Prussin, C.2    Sacks, D.L.3    Seder, R.A.4
  • 53
    • 0033624828 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides and IL-12 improve the efficacy of BCG vaccination in mice challenged with Mycobacterium tuberculosis
    • Freidag B.L., Melton G.B., Collins F., Klinman D., Cheever A., Stobie L., Suen W., Seder R.A. CpG oligodeoxynucleotides and IL-12 improve the efficacy of BCG vaccination in mice challenged with Mycobacterium tuberculosis. Infect Immun. 68:2000;2948-2953.
    • (2000) Infect Immun , vol.68 , pp. 2948-2953
    • Freidag, B.L.1    Melton, G.B.2    Collins, F.3    Klinman, D.4    Cheever, A.5    Stobie, L.6    Suen, W.7    Seder, R.A.8
  • 54
    • 0033566165 scopus 로고    scopus 로고
    • Therapy of tuberculosis in mice by DNA vaccination
    • Recent paper suggesting that DNA vaccination may be effective as a therapeutic vaccine for systemic tuberculosis infection
    • Lowie D.B., Tascon R.E., Bonato V.L.D., Lima V.M.F., Faccioli L.H., Stavropoulos E., Colston M.J., Hewinson R.G., Moelling K., Silva C.L. Therapy of tuberculosis in mice by DNA vaccination. Nature. 400:1999;269-271. Recent paper suggesting that DNA vaccination may be effective as a therapeutic vaccine for systemic tuberculosis infection.
    • (1999) Nature , vol.400 , pp. 269-271
    • Lowie, D.B.1    Tascon, R.E.2    Bonato, V.L.D.3    Lima, V.M.F.4    Faccioli, L.H.5    Stavropoulos, E.6    Colston, M.J.7    Hewinson, R.G.8    Moelling, K.9    Silva, C.L.10


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