-
1
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
M. Arrasate, S. Mitra, E.S. Schweitzer, M.R. Segal, and S. Finkbeiner Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death Nature 431 2004 805 810
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
2
-
-
0036743483
-
Targeted expression of dominant negative proteasome mutants in Drosophila melanogaster
-
J.M. Belote, and E. Fortier Targeted expression of dominant negative proteasome mutants in Drosophila melanogaster Genesis 34 2002 80 82
-
(2002)
Genesis
, vol.34
, pp. 80-82
-
-
Belote, J.M.1
Fortier, E.2
-
3
-
-
0037059040
-
Chaperoning brain degeneration
-
10.1073/pnas.152330499
-
N.M. Bonini Chaperoning brain degeneration Proc. Natl. Acad. Sci. USA 99 2002 16407 16411 10.1073/pnas.152330499
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16407-16411
-
-
Bonini, N.M.1
-
4
-
-
0042035602
-
Human neurodegenerative disease modeling using Drosophila
-
N.M. Bonini, and M.E. Fortini Human neurodegenerative disease modeling using Drosophila Annu. Rev. Neurosci. 26 2003 627 656
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 627-656
-
-
Bonini, N.M.1
Fortini, M.E.2
-
5
-
-
0345099501
-
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitinylated proteins and has ubiquitin protease activity
-
B. Burnett, F. Li, and R.N. Pittman The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitinylated proteins and has ubiquitin protease activity Hum. Mol. Genet. 12 2003 3195 3205
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3195-3205
-
-
Burnett, B.1
Li, F.2
Pittman, R.N.3
-
6
-
-
0942287194
-
Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways
-
Y. Chai, S.S. Berke, R.E. Cohen, and H.L. Paulson Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways J. Biol. Chem. 279 2004 3605 3611
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3605-3611
-
-
Chai, Y.1
Berke, S.S.2
Cohen, R.E.3
Paulson, H.L.4
-
7
-
-
0034703863
-
Mechanisms of chaperone suppression of polyglutamine disease: Selectivity, synergy and modulation of protein solubility in Drosophila
-
H.Y. Chan, J.M. Warrick, G.L. Gray-Board, H.L. Paulson, and N.M. Bonini Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila Hum. Mol. Genet. 9 2000 2811 2820
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2811-2820
-
-
Chan, H.Y.1
Warrick, J.M.2
Gray-Board, G.L.3
Paulson, H.L.4
Bonini, N.M.5
-
8
-
-
0037726598
-
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1
-
H.K. Chen, P. Fernandez-Funez, S.F. Acevedo, Y.C. Lam, M.D. Kaytor, M.H. Fernandez, A. Aitken, E.M. Skoulakis, H.T. Orr, J. Botas, and H.Y. Zoghbi Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1 Cell 113 2003 457 468
-
(2003)
Cell
, vol.113
, pp. 457-468
-
-
Chen, H.K.1
Fernandez-Funez, P.2
Acevedo, S.F.3
Lam, Y.C.4
Kaytor, M.D.5
Fernandez, M.H.6
Aitken, A.7
Skoulakis, E.M.8
Orr, H.T.9
Botas, J.10
Zoghbi, H.Y.11
-
9
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
T.M. Dawson, and V.L. Dawson Molecular pathways of neurodegeneration in Parkinson's disease Science 302 2003 819 822
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
10
-
-
0035954743
-
Ubiquitination-dependent mechanisms regulate synaptic growth and function
-
A. DiAntonio, A.P. Haghighi, S.L. Portman, J.D. Lee, A.M. Amaranto, and C.S. Goodman Ubiquitination-dependent mechanisms regulate synaptic growth and function Nature 412 2001 449 452
-
(2001)
Nature
, vol.412
, pp. 449-452
-
-
Diantonio, A.1
Haghighi, A.P.2
Portman, S.L.3
Lee, J.D.4
Amaranto, A.M.5
Goodman, C.S.6
-
11
-
-
0042808497
-
Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates
-
K. Donaldson, W. Li, K. Ching, S. Batalov, C. Tsai, and C. Joazeiro Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates Proc. Natl. Acad. Sci. USA 100 2003 8892 8897
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8892-8897
-
-
Donaldson, K.1
Li, W.2
Ching, K.3
Batalov, S.4
Tsai, C.5
Joazeiro, C.6
-
12
-
-
0042691818
-
Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis
-
E.W. Doss-Pepe, E.S. Stenroos, W.G. Johnsonm, and K. Madura Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis Mol. Cell. Biol. 23 2003 6469 6483
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6469-6483
-
-
Doss-Pepe, E.W.1
Stenroos, E.S.2
Johnsonm, W.G.3
Madura, K.4
-
13
-
-
0037373633
-
Dying for a cause: Invertebrate genetics takes on human neurodegeneration
-
M. Driscoll, and B. Gerstbrein Dying for a cause: invertebrate genetics takes on human neurodegeneration Nat. Rev. Genet. 4 2003 181 194
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 181-194
-
-
Driscoll, M.1
Gerstbrein, B.2
-
14
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
M.B. Feany, and W.W. Bender A Drosophila model of Parkinson's disease Nature 404 2000 394 398
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
15
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
P. Fernandez-Funez, M.L. Nino-Rosales, B. de Gouyon, W.-C. She, J.M. Luchak, P. Martinez, E. Turiegano, J. Benito, M. Capovilla, and P.J. Skinner Identification of genes that modify ataxin-1-induced neurodegeneration Nature 408 2000 101 106
-
(2000)
Nature
, vol.408
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
De Gouyon, B.3
She, W.-C.4
Luchak, J.M.5
Martinez, P.6
Turiegano, E.7
Benito, J.8
Capovilla, M.9
Skinner, P.J.10
-
16
-
-
3242696232
-
Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain
-
K. Flick, I. Ouni, J.A. Wohlschlegel, C. Capati, W.H. McDonald, J.R. Yates, and P. Kaiser Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain Nat. Cell Biol. 6 2004 634 641
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 634-641
-
-
Flick, K.1
Ouni, I.2
Wohlschlegel, J.A.3
Capati, C.4
McDonald, W.H.5
Yates, J.R.6
Kaiser, P.7
-
17
-
-
0033802841
-
Ataxin-3 is translocated into the nucleus for the formation of intranuclear inclusions in normal and Machado-Joseph disease brains
-
H. Fujigasaki, T. Uchihara, S. Koyano, K. Iwabuchi, S. Yagishita, T. Makifuchi, A. Nakamura, K. Ishida, S. Toru, and S. Hirai Ataxin-3 is translocated into the nucleus for the formation of intranuclear inclusions in normal and Machado-Joseph disease brains Exp. Neurol. 165 2000 248 256
-
(2000)
Exp. Neurol.
, vol.165
, pp. 248-256
-
-
Fujigasaki, H.1
Uchihara, T.2
Koyano, S.3
Iwabuchi, K.4
Yagishita, S.5
Makifuchi, T.6
Nakamura, A.7
Ishida, K.8
Toru, S.9
Hirai, S.10
-
18
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
A.L. Goldberg Protein degradation and protection against misfolded or damaged proteins Nature 426 2003 895 899
-
(2003)
Nature
, vol.426
, pp. 895-899
-
-
Goldberg, A.L.1
-
19
-
-
0037134015
-
Recruitment of a 19S proteasome subcomplex to an activated promoter
-
F. Gonzalez, A. Delahodde, T. Kodadek, and S.A. Johnston Recruitment of a 19S proteasome subcomplex to an activated promoter Science 296 2002 548 550
-
(2002)
Science
, vol.296
, pp. 548-550
-
-
Gonzalez, F.1
Delahodde, A.2
Kodadek, T.3
Johnston, S.A.4
-
20
-
-
20844462057
-
A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration
-
D. Goti, S.M. Katzen, J. Mez, N. Kurtis, J. Kiluk, L. Ben-Haiem, N.A. Jenkins, N.G. Copeland, A. Kakizuka, and A.H. Sharp A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration J. Neurosci. 24 2004 10266 10279
-
(2004)
J. Neurosci.
, vol.24
, pp. 10266-10279
-
-
Goti, D.1
Katzen, S.M.2
Mez, J.3
Kurtis, N.4
Kiluk, J.5
Ben-Haiem, L.6
Jenkins, N.A.7
Copeland, N.G.8
Kakizuka, A.9
Sharp, A.H.10
-
21
-
-
0034329159
-
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
-
J.F. Gusella, and M.E. MacDonald Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease Nat. Rev. Neurosci. 1 2000 109 115
-
(2000)
Nat. Rev. Neurosci.
, vol.1
, pp. 109-115
-
-
Gusella, J.F.1
MacDonald, M.E.2
-
23
-
-
0036122933
-
Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration
-
H. Higashiyama, F. Hirose, M. Yamaguchi, Y.H. Inoue, N. Fujikake, A. Matsukage, and A. Kakizuka Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration Cell Death Differ. 9 2002 264 273
-
(2002)
Cell Death Differ.
, vol.9
, pp. 264-273
-
-
Higashiyama, H.1
Hirose, F.2
Yamaguchi, M.3
Inoue, Y.H.4
Fujikake, N.5
Matsukage, A.6
Kakizuka, A.7
-
24
-
-
0030457014
-
Ubiquitin-dependent protein degradation
-
M. Hochstrasser Ubiquitin-dependent protein degradation Annu. Rev. Genet. 30 1996 405 439
-
(1996)
Annu. Rev. Genet.
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
25
-
-
0035369556
-
A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems
-
K. Hofmann, and L. Falquet A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems Trends Biochem. Sci. 26 2001 347 350
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 347-350
-
-
Hofmann, K.1
Falquet, L.2
-
26
-
-
0030058208
-
Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo
-
H. Ikeda, M. Yamaguchi, S. Sugai, Y. Aze, S. Narumiya, and A. Kakizuka Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo Nat. Genet. 13 1996 196 202
-
(1996)
Nat. Genet.
, vol.13
, pp. 196-202
-
-
Ikeda, H.1
Yamaguchi, M.2
Sugai, S.3
Aze, Y.4
Narumiya, S.5
Kakizuka, A.6
-
27
-
-
0032168160
-
Polyglutamine-expanded human Huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons
-
G. Jackson, I. Salecker, X. Dong, X. Yao, N. Arnheim, P. Faber, M. MacDonald, and S.L. Zipursky Polyglutamine-expanded human Huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons Neuron 21 1998 633 642
-
(1998)
Neuron
, vol.21
, pp. 633-642
-
-
Jackson, G.1
Salecker, I.2
Dong, X.3
Yao, X.4
Arnheim, N.5
Faber, P.6
MacDonald, M.7
Zipursky, S.L.8
-
28
-
-
0038521282
-
Polyglutamines placed into context
-
A.R. La Spada, and J.P. Taylor Polyglutamines placed into context Neuron 38 2003 681 684
-
(2003)
Neuron
, vol.38
, pp. 681-684
-
-
La Spada, A.R.1
Taylor, J.P.2
-
29
-
-
0035127907
-
Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo
-
B.R. Leavitt, J.A. Guttman, J.G. Hodgson, G.H. Kimel, R. Singaraja, A.W. Vogl, and M.R. Hayden Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo Am. J. Hum. Genet. 68 2001 313 324
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 313-324
-
-
Leavitt, B.R.1
Guttman, J.A.2
Hodgson, J.G.3
Kimel, G.H.4
Singaraja, R.5
Vogl, A.W.6
Hayden, M.R.7
-
30
-
-
0029864225
-
Machado-Joseph disease: Correlation between the clinical features, the CAG repeat length and homozygosity for the mutation
-
I. Lerer, D. Merims, D. Abeliovich, J. Zlotogora, and N. Gadoth Machado-Joseph disease: correlation between the clinical features, the CAG repeat length and homozygosity for the mutation Eur. J. Hum. Genet. 4 1996 3 7
-
(1996)
Eur. J. Hum. Genet.
, vol.4
, pp. 3-7
-
-
Lerer, I.1
Merims, D.2
Abeliovich, D.3
Zlotogora, J.4
Gadoth, N.5
-
32
-
-
1442264782
-
Molecular clearance of ataxin-3 is regulated by a mammalian E4
-
M. Matsumoto, M. Yada, S. Hatakeyama, H. Ishimoto, T. Tanimura, S. Tsuji, A. Kakizuka, M. Kitagawa, and K.I. Nakayama Molecular clearance of ataxin-3 is regulated by a mammalian E4 EMBO J. 23 2004 659 669
-
(2004)
EMBO J.
, vol.23
, pp. 659-669
-
-
Matsumoto, M.1
Yada, M.2
Hatakeyama, S.3
Ishimoto, H.4
Tanimura, T.5
Tsuji, S.6
Kakizuka, A.7
Kitagawa, M.8
Nakayama, K.I.9
-
33
-
-
0032517816
-
Recruitment and the role of nuclear localization in polyglutamine- mediated aggregation
-
M.K. Perez, H.L. Paulson, S.J. Pendse, S.J. Saionz, N. Bonini, and R.N. Pittman Recruitment and the role of nuclear localization in polyglutamine- mediated aggregation J. Cell Biol. 143 1998 1457 1470
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1457-1470
-
-
Perez, M.K.1
Paulson, H.L.2
Pendse, S.J.3
Saionz, S.J.4
Bonini, N.5
Pittman, R.N.6
-
34
-
-
0035979738
-
Regulation of transcriptional activation domain function by ubiquitin
-
S.E. Salghetti, A.A. Caudy, J.G. Chenoweth, and W.P. Tansey Regulation of transcriptional activation domain function by ubiquitin Science 293 2001 1651 1653
-
(2001)
Science
, vol.293
, pp. 1651-1653
-
-
Salghetti, S.E.1
Caudy, A.A.2
Chenoweth, J.G.3
Tansey, W.P.4
-
35
-
-
0027359037
-
Identification of an essential gene, l(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunit
-
K.J. Saville, and J.M. Belote Identification of an essential gene, l(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunit Proc. Natl. Acad. Sci. USA 90 1993 8842 8846
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8842-8846
-
-
Saville, K.J.1
Belote, J.M.2
-
36
-
-
0242693202
-
Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics
-
H. Scheel, S. Tomiuk, and K. Hofmann Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics Hum. Mol. Genet. 12 2003 2845 2852
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2845-2852
-
-
Scheel, H.1
Tomiuk, S.2
Hofmann, K.3
-
37
-
-
0033613272
-
Dominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage
-
F. Schweisguth Dominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage Proc. Natl. Acad. Sci. USA 96 1999 11382 11386
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 11382-11386
-
-
Schweisguth, F.1
-
38
-
-
3242736666
-
Amyotrophic lateral sclerosis with neuronal intranuclear protein inclusions
-
D. Seilhean, J. Takahashi, K.H. El Hachimi, H. Fujigasaki, A.S. Lebre, V. Biancalana, A. Durr, F. Salachas, J. Hogenhuis, and H. De The Amyotrophic lateral sclerosis with neuronal intranuclear protein inclusions Acta Neuropathol. (Berl.) 108 2004 81 87
-
(2004)
Acta Neuropathol. (Berl.)
, vol.108
, pp. 81-87
-
-
Seilhean, D.1
Takahashi, J.2
El Hachimi, K.H.3
Fujigasaki, H.4
Lebre, A.S.5
Biancalana, V.6
Durr, A.7
Salachas, F.8
Hogenhuis, J.9
De The, H.10
-
39
-
-
0042627722
-
From fruit fly to bedside: Translating lessons from Drosophila models of neurodegenerative disease
-
J.M. Shulman, L.M. Shulman, W.J. Weiner, and M.B. Feany From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease Curr. Opin. Neurol. 16 2003 443 449
-
(2003)
Curr. Opin. Neurol.
, vol.16
, pp. 443-449
-
-
Shulman, J.M.1
Shulman, L.M.2
Weiner, W.J.3
Feany, M.B.4
-
40
-
-
0032897575
-
The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit
-
K.A. Smyth, and J.M. Belote The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit Genetics 151 1999 211 220
-
(1999)
Genetics
, vol.151
, pp. 211-220
-
-
Smyth, K.A.1
Belote, J.M.2
-
41
-
-
0029878024
-
Homozygosity for Machado-Joseph disease gene enhances phenotypic severity
-
G. Sobue, M. Doyu, N. Nakao, N. Shimada, T. Mitsuma, H. Maruyama, S. Kawakami, and S. Nakamura Homozygosity for Machado-Joseph disease gene enhances phenotypic severity J. Neurol. Neurosurg. Psychiatry 60 1996 354 356
-
(1996)
J. Neurol. Neurosurg. Psychiatry
, vol.60
, pp. 354-356
-
-
Sobue, G.1
Doyu, M.2
Nakao, N.3
Shimada, N.4
Mitsuma, T.5
Maruyama, H.6
Kawakami, S.7
Nakamura, S.8
-
42
-
-
0037379416
-
Homozygosity for CAG mutation in Huntington disease is associated with a more severe clinical course
-
F. Squitieri, C. Gellera, M. Cannella, C. Mariotti, G. Cislaghi, D.C. Rubinsztein, E.W. Almqvist, D. Turner, A.C. Bachoud-Levi, and S.A. Simpson Homozygosity for CAG mutation in Huntington disease is associated with a more severe clinical course Brain 126 2003 946 955
-
(2003)
Brain
, vol.126
, pp. 946-955
-
-
Squitieri, F.1
Gellera, C.2
Cannella, M.3
Mariotti, C.4
Cislaghi, G.5
Rubinsztein, D.C.6
Almqvist, E.W.7
Turner, D.8
Bachoud-Levi, A.C.9
Simpson, S.A.10
-
43
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
J.S. Steffan, L. Bodai, J. Pallos, M. Poelman, A. McCampbell, B.L. Apostol, A. Kazantsev, E. Schmidt, Y.Z. Zhu, and M. Greenwald Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila Nature 413 2001 739 743
-
(2001)
Nature
, vol.413
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
Poelman, M.4
McCampbell, A.5
Apostol, B.L.6
Kazantsev, A.7
Schmidt, E.8
Zhu, Y.Z.9
Greenwald, M.10
-
44
-
-
0026919289
-
No-bridge of Drosophila melanogaster: Portrait of a structural brain mutant of the central complex
-
R. Strauss, U. Hanesch, M. Kinkelin, R. Wolf, and M. Heisenberg No-bridge of Drosophila melanogaster: portrait of a structural brain mutant of the central complex J. Neurogenet. 8 1992 125 155
-
(1992)
J. Neurogenet.
, vol.8
, pp. 125-155
-
-
Strauss, R.1
Hanesch, U.2
Kinkelin, M.3
Wolf, R.4
Heisenberg, M.5
-
45
-
-
0035060505
-
Recruitment of nonexpanded polyglutamine proteins to intranuclear aggregates in neuronal intranuclear hyaline inclusion disease
-
J. Takahashi, J. Tanaka, K. Arai, N. Funata, T. Hattori, T. Fukuda, H. Fujigasaki, and T. Uchihara Recruitment of nonexpanded polyglutamine proteins to intranuclear aggregates in neuronal intranuclear hyaline inclusion disease J. Neuropathol. Exp. Neurol. 60 2001 369 376
-
(2001)
J. Neuropathol. Exp. Neurol.
, vol.60
, pp. 369-376
-
-
Takahashi, J.1
Tanaka, J.2
Arai, K.3
Funata, N.4
Hattori, T.5
Fukuda, T.6
Fujigasaki, H.7
Uchihara, T.8
-
46
-
-
0037194896
-
Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila
-
K. Takeyama, S. Ito, A. Yamamoto, H. Tanimoto, T. Furutani, H. Kanuka, M. Miura, T. Tabata, and S. Kato Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila Neuron 35 2002 855 864
-
(2002)
Neuron
, vol.35
, pp. 855-864
-
-
Takeyama, K.1
Ito, S.2
Yamamoto, A.3
Tanimoto, H.4
Furutani, T.5
Kanuka, H.6
Miura, M.7
Tabata, T.8
Kato, S.9
-
47
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
J.P. Taylor, J. Hardy, and K.H. Fischbeck Toxic proteins in neurodegenerative disease Science 296 2002 1991 1995
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
49
-
-
0034887539
-
Non-expanded polyglutamine proteins in intranuclear inclusions of hereditary ataxias-triple-labeling immunofluorescence study
-
T. Uchihara, H. Fujigasaki, S. Koyano, A. Nakamura, S. Yagishita, and K. Iwabuchi Non-expanded polyglutamine proteins in intranuclear inclusions of hereditary ataxias-triple-labeling immunofluorescence study Acta Neuropathol. (Berl.) 102 2001 149 152
-
(2001)
Acta Neuropathol. (Berl.)
, vol.102
, pp. 149-152
-
-
Uchihara, T.1
Fujigasaki, H.2
Koyano, S.3
Nakamura, A.4
Yagishita, S.5
Iwabuchi, K.6
-
50
-
-
3142566639
-
Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system
-
R. Verma, R. Oania, J. Graumann, and R.J. Deshaies Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system Cell 118 2004 99 110
-
(2004)
Cell
, vol.118
, pp. 99-110
-
-
Verma, R.1
Oania, R.2
Graumann, J.3
Deshaies, R.J.4
-
51
-
-
0033867992
-
Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B
-
G. Wang, N. Sawai, S. Kotliarova, I. Kanazawa, and N. Nukina Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B Hum. Mol. Genet. 9 2000 1795 1803
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1795-1803
-
-
Wang, G.1
Sawai, N.2
Kotliarova, S.3
Kanazawa, I.4
Nukina, N.5
-
52
-
-
18544392423
-
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
-
J.M. Warrick, H. Paulson, G.L. Gray-Board, Q.T. Bui, K. Fischbeck, R.N. Pittman, and N.M. Bonini Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila Cell 93 1998 939 949
-
(1998)
Cell
, vol.93
, pp. 939-949
-
-
Warrick, J.M.1
Paulson, H.2
Gray-Board, G.L.3
Bui, Q.T.4
Fischbeck, K.5
Pittman, R.N.6
Bonini, N.M.7
-
53
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
C.W. Wittmann, M.F. Wszolek, J.M. Shulman, P.M. Salvaterra, J. Lewis, M. Hutton, and M.B. Feany Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles Science 293 2001 711 714
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
54
-
-
0032736793
-
Genetic analysis of the role of the Drosophila fat facets gene in the ubiquitin pathway
-
Z. Wu, Q. Li, M.E. Fortini, and J.A. Fischer Genetic analysis of the role of the Drosophila fat facets gene in the ubiquitin pathway Dev. Genet. 25 1999 312 320
-
(1999)
Dev. Genet.
, vol.25
, pp. 312-320
-
-
Wu, Z.1
Li, Q.2
Fortini, M.E.3
Fischer, J.A.4
-
55
-
-
0036720019
-
Mouse and fly models of neurodegeneration
-
H.Y. Zoghbi, and J. Botas Mouse and fly models of neurodegeneration Trends Genet. 18 2002 463 471
-
(2002)
Trends Genet.
, vol.18
, pp. 463-471
-
-
Zoghbi, H.Y.1
Botas, J.2
-
56
-
-
0034094873
-
Glutamine repeats and neurodegeneration
-
H.Y. Zoghbi, and H.T. Orr Glutamine repeats and neurodegeneration Annu. Rev. Neurosci. 23 2000 214 247
-
(2000)
Annu. Rev. Neurosci.
, vol.23
, pp. 214-247
-
-
Zoghbi, H.Y.1
Orr, H.T.2
-
57
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
C. Zuccato, A. Ciammola, D. Rigamonti, B.R. Leavitt, D. Goffredo, L. Conti, M.E. MacDonald, R.M. Friedlander, V. Silani, and M.R. Hayden Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease Science 293 2001 493 498
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
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