Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue

Experimental Gerontology

Volumn 41, Issue 2, 2006, Pages 157-168

  Massip, Laurent ^a   Garand, Chantal ^a   Turaga, Ramachander V N ^a   Deschênes, François ^a   Thorin, Eric ^b   Lebel, Michel ^a  

^a LAVAL UNIVERSITY   (Canada)

^b MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Cardiovascular disease; Hypercholesterolemia; Hyperglycemia; Hyperinsulinemia; Hypertriglyceridemia; Mouse DNA helicase; Oxidative stress; Werner syndrome

Indexed keywords

CHOLESTEROL; GLUCOSE; HELICASE; HYALURONIC ACID; INSULIN; REACTIVE OXYGEN METABOLITE; TRIACYLGLYCEROL; WERNER SYNDROME PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA STENOSIS; ARTICLE; CARDIOMYOPATHY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA DAMAGE; GENE MUTATION; GLUCOSE BLOOD LEVEL; HEART FAILURE; HEART FUNCTION; HEART HEMODYNAMICS; HEART MUSCLE FIBROSIS; INSULIN RESISTANCE; LIPID STORAGE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; DNA HELICASES; FIBROSIS; GENE DELETION; INSULIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MUTATION; MYOCARDIUM; PROTEIN STRUCTURE, TERTIARY; REACTIVE OXYGEN SPECIES; RECQ HELICASES; SEQUENCE HOMOLOGY; TRIGLYCERIDES;

ANIMALIA; MURINAE;

EID: 31544474304     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2005.10.011     Document Type: Article

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