All patients with Werner's syndrome are insulin resistant, but only those who also have impaired insulin secretion develop overt diabetes [11]

Diabetes Care

Volumn 22, Issue 12, 1999, Pages 2094-2095

  Yamada, Kazunori ^a   Ikegami, Hiroshi ^a,b   Yoneda, Hiroko ^a   Miki, Tetsuro ^a   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE MUTATION; GLUCOSE TOLERANCE; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; LETTER; MALE; WERNER SYNDROME;

EID: 0033361074     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.22.12.2094     Document Type: Letter

References (4)

1. Field JB, Loube SD: Observations concerning diabetes mellitus associated with Werner's syndrome. Metabolism 9:118-124, 1960
2. Epstein CJ, Martin GM, Schultz AL, Motulsky AG: Werners syndrome: a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine 45:177-221, 1966
3. Miki T, Nakura J, Ye L, Mitsuda N, Morishima A, Sato N, Kamino K, Ogihara T: Molecular and epidemiological studies of Wemer Syndrome in the Japanese population. Mech Ageing Dev 98:255-265, 1997
4. Yoneda H, Ikegami H, Yamamoto Y, Yamato E, Cha T, Kawaguchi Y, Tahara Y, Ogihara T: Analysis of early-phase insulin responses in nonobese subjects with mild glucose intolerance. Diabetes Care 15: 1517-1521, 1992