Increased frequency of multiradial chromosome structures in mouse embryonic fibroblasts lacking functional Werner syndrome protein and poly(ADP-ribose) polymerase-1

Cancer Genetics and Cytogenetics

Volumn 156, Issue 2, 2005, Pages 134-143

  Lavoie, Josée ^a   Carter, Ronald ^b   Drouin, Régen ^a   Lebel, Michel ^a  

^a LAVAL UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; WERNER SYNDROME PROTEIN;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CHROMATID; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME BAND; CHROMOSOME BREAKAGE; CHROMOSOME STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; DNA STRAND BREAKAGE; EMBRYO; EMBRYO CELL; FIBROBLAST; GENE FREQUENCY; GENE MUTATION; GENE REARRANGEMENT; KARYOTYPING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; CHROMOSOME MAPPING; DIPLOIDY; DNA HELICASES; FIBROBLASTS; KARYOTYPING; MICE; MICE, KNOCKOUT; POLY(ADP-RIBOSE) POLYMERASES; RECQ HELICASES; WERNER SYNDROME;

EID: 11844250625     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2004.05.005     Document Type: Article

References (27)

1. M. Goto, R.W. Miller, Y. Ishikawa, and H. Sugano Excess of rare cancers in Werner syndrome (adult progeria) Cancer Epidemiol Biomarkers Prev 5 1996 239 246
2. C.E. Yu, J. Oshima, Y. Fu, E.M. Wijsman, F. Hisama, R. Alish, S. Matthews, J. Nakura, T. Miki, S. Quais, G.M. Martin, J. Mulligan, and G.D. Schellenberg Positional cloning of the Werner's syndrome gene Science 272 1996 258 262
3. J.C. Shen, M.D. Gray, J. Oshima, A.S. Kamath-Loeb, M. Fry, and L.A. Loeb Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide J Biol Chem 273 1998 34139 34144
4. S. Scappaticci, D. Cerimele, and M. Fraccaro Clonal structural chromosomal rearrangements in primary fibroblasts and in lymphocytes of patients with Werner's syndrome Hum Genet 62 1982 16 24
5. S. Schonberg, M.F. Niermeijer, D. Bootsma, E. Henderson, and J. German Werner's syndrome: proliferation in vitro of clones of cells bearing chromosome translocations Am J Hum Genet 36 1984 387 397
6. H. Tahara, Y. Tokutake, S. Maeda, H. Kataoka, T. Watanabe, M. Satoh, T. Matsumoto, M. Sugawara, T. Ide, M. Goto, Y. Furuichi, and M. Sugimoto Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus Oncogene 15 1997 1911 1920
7. M. Lebel, and P. Leder A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity Proc Natl Acad Sci USA 95 1998 13097 13102
8. R. Elli, L. Chessa, A. Antonelli, P. Petrinelli, R. Ambra, and L. Marcucci Effects of topoisomerase II inhibition in lymphoblasts from patients with progeroid and "chromosome instability" syndromes Cancer Genet Cytogenet 87 1996 112 116
9. M. Poot, K.A. Gollahon, and P.S. Rabinovitch Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase Hum Genet 104 1999 10 14
10. M. Lebel Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue Carcinogenesis 23 2002 213 216
11. A. Leder, M. Lebel, F. Zhou, K. Fontaine, A. Bishop, and P. Leder Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis Oncogene 21 2002 6657 6668
12. M. Masutani, T. Nozaki, K. Nakamoto, H. Nakagama, H. Suzuki, O. Kusuoka, M. Tsutsumi, and T. Sugimura The response of Parp knockout mice against DNA damaging agents Mutat Res 462 2000 159 166
13. J. Ménissier de Murcia, C. Niedergang, C. Trucco, M. Ricoul, B. Dutrillaux, M. Mark, F.J. Olive, M. Masson, A. Dierich, M. LeMeur, C. Walztinger, P. Chambon, and G. de Murcia Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells Proc Natl Acad Sci USA 94 1997 7303 7307
14. Y. Le Rhun, J.B. Kirkland, and G.M. Shah Cellular responses to DNA damage in the absence of poly(ADP-ribose) polymerase Biochem Biophys Res Commun 245 1998 1 10
15. Z.Q. Wang, L. Stingl, C. Morrison, M. Jantsch, M. Los, K. Schulze-Osthoff, and E.F. Wagner PARP is important for genomic stability but dispensable in apoptosis Genes Dev 11 1997 2347 2358
16. E. Samper, F.A. Goytisolo, J. Menissier-de Murcia, E. Gonzalez-Suarez, J. Cigudosa, G. de Murcia, and M.A. Blasco Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability J Cell Biol 154 2001 49 60
17. C.M. Simbulan-Rosenthal, D.H. Ly, D.S. Rosenthal, G. Konopka, R. Luo, Z.Q. Wang, P.G. Schultz, and M.E. Smulson Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase Proc Natl Acad Sci USA 97 2000 11274 11279
18. M. Lebel, J. Lavoie, I. Gaudreault, M. Bronsard, and R. Drouin Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice Am J Pathol 162 2003 1559 1569
19. Z.Q. Wang, B. Auer, L. Stingl, H. Berghammer, D. Haidacher, M. Schweiger, and E.F. Wagner Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease Genes Dev 9 1995 509 520
20. R. Drouin, N. Lemieux, and C.L. Richer High-resolution R-banding at the 1250-band level. 1. Technical considerations on cell synchronization and R-banding (RHG and RBG) Cytobios 56 1988 107 125
21. M. Liyanage, A. Coleman, S. du Manoir, T. Veldman, S. McCormack, R.B. Dickson, C. Barlow, A. Wynshaw-Boris, S. Janz, J. Wienberg, M.A. Ferguson-Smith, E. Schrock, and T. Ried Multicolour spectral karyotyping of mouse chromosomes Nat Genet 14 1996 312 315
22. T.W. Glover Instability at chromosomal fragile sites Recent Results Cancer Res 154 1998 185 199
23. M.M. Sanz, E.C. Jenkins, W.T. Brown, M.T. Davisson, M.J. Kevin, T.H. Roderick, W.P. Silverman, and H.M. Wisniewski Mouse chromosome fragility Am J Med Genet 23 1986 491 509
24. M. Djalali, S. Adolph, P. Steinbac, H. Winking, and H. Hameister Fragile sites induced by 5-azacytidine and 5-azadeoxycytidine in the murine genome Hereditas 112 1990 77 81
25. M. Lebel Werner syndrome: genetic and molecular basis of a premature aging disorder Cell Mol Life Sci 58 2001 857 867
26. T. Shiraishi, T. Druck, K. Mimori, J. Flomenberg, L. Berk, H. Alder, W. Miller, K. Huebner, and C.M. Croce Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit Proc Natl Acad Sci USA 98 2001 5722 5727
27. M.F. Arlt, D.E. Miller, D.G. Beer, and T.W. Glover Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells Genes Chromosomes Cancer 33 2002 82 92