Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover

Biochemical Journal

Volumn 359, Issue 2, 2001, Pages 459-464

  Dumaz, N ^a   Milne, D M ^a   Jardine, L J ^a   Meek, D W ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

DNA damage; Tumour suppressor; Ubiquitination

Indexed keywords

BIODEGRADATION; CELLS; DNA; PROTEINS;

APOPTOSIS; PHOSPHORYLATION;

AMINO ACIDS;

DNA; DNA BINDING PROTEIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PROTEIN P53; SERINE;

ANIMAL CELL; ARTICLE; ATAXIA TELANGIECTASIA; CANCER CELL CULTURE; DNA DAMAGE; GENE MUTATION; HUMAN; HUMAN CELL; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; TUMOR SUPPRESSOR GENE;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CELL CYCLE PROTEINS; COS CELLS; DNA DAMAGE; DNA-BINDING PROTEINS; HUMANS; MICE; MUTAGENESIS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; SERINE; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0035887213     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3590459     Document Type: Article

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