Structural model of MD-2 and functional role of its basic amino acid clusters involved in cellular lipopolysaccharide recognition

Journal of Biological Chemistry

Volumn 279, Issue 27, 2004, Pages 28475-28482

  Gruber, Anton ^a   Manček, Mateja ^b   Wagner, Hermann ^a   Kirschning, Carsten J ^a   Jerala, Roman ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; CHOLESTEROL; LIPIDS; POLYSACCHARIDES; PROTEINS;

PEPTIDES; RECEPTOR COMPLEXES;

BIOCHEMISTRY;

ARGININE; BACTERIAL PROTEIN; BINDING PROTEIN; CHOLESTEROL; CYSTEINE; GANGLIOSIDE GM2; GANGLIOSIDE GM2 ACTIVATOR PROTEIN; HOUSE DUST ALLERGEN; INTERLEUKIN 8; LIPID BINDING PROTEIN; LIPOPOLYSACCHARIDE; LYSINE; MUTANT PROTEIN; PROTEIN; PROTEIN MD 2; PROTEIN NPC2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CELL MEMBRANE; CIRCULAR DICHROISM; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; MODEL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; ANTIGENS, SURFACE; CARRIER PROTEINS; CELL LINE; CIRCULAR DICHROISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MEMBRANE GLYCOPROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDES; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

ACARI; BACTERIA (MICROORGANISMS);

EID: 3142546368     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400993200     Document Type: Article

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