-
1
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
Aderem, A., and R. J. Ulevitch. 2000. Toll-like receptors in the induction of the innate immune response. Nature 406:782.
-
(2000)
Nature
, vol.406
, pp. 782
-
-
Aderem, A.1
Ulevitch, R.J.2
-
2
-
-
0036067659
-
Toll receptors. CD14, and macrophage activation and deactivation by LPS
-
Dobrovolskaia, M. A., and S. N. Vogel. 2002. Toll receptors. CD14, and macrophage activation and deactivation by LPS. Microbes Infect. 4:903.
-
(2002)
Microbes Infect.
, vol.4
, pp. 903
-
-
Dobrovolskaia, M.A.1
Vogel, S.N.2
-
3
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431.
-
(1990)
Science
, vol.249
, pp. 1431
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
4
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira, S., K. Takeda, and T. Kaisho. 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:675.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 675
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
5
-
-
0036467392
-
Toll-like receptors: Key mediators of microbe detection
-
Underhill, D. M., and A. Ozinsky. 2002. Toll-like receptors: key mediators of microbe detection. Curr. Opin. Immunol. 14:103.
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 103
-
-
Underhill, D.M.1
Ozinsky, A.2
-
6
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A., X. He, I. Smirnova, M. Y. Liu, C. V. Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282:2085.
-
(1998)
Science
, vol.282
, pp. 2085
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Huffel, C.V.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
7
-
-
0345561540
-
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
-
Qureshi, S. T., L. Lariviere, G. Leveque, S. Clermont, K. J. Moore, P. Gros, and D. Malo. 1999. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189:615.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 615
-
-
Qureshi, S.T.1
Lariviere, L.2
Leveque, G.3
Clermont, S.4
Moore, K.J.5
Gros, P.6
Malo, D.7
-
8
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino, K., O. Takeuchi, T. Kawai, H. Sanjo, T. Ogawa, Y. Takeda, K. Takeda, and S. Akira. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162:3749.
-
(1999)
J. Immunol.
, vol.162
, pp. 3749
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
9
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu, R., S. Akashi, H. Ogata, Y. Nagai, K. Fukudome, K. Miyake, and M. Kimoto. 1999. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:1777.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1777
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
Kimoto, M.7
-
10
-
-
0035796406
-
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling
-
Schromm, A. B., E. Lien, P. Henneke, J. C. Chow, A. Yoshimura, H. Heine, E. Latz, B. G. Monks, D. A. Schwartz, K. Miyake, and D. T. Golenbock. 2001. Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J. Exp. Med. 194:79.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 79
-
-
Schromm, A.B.1
Lien, E.2
Henneke, P.3
Chow, J.C.4
Yoshimura, A.5
Heine, H.6
Latz, E.7
Monks, B.G.8
Schwartz, D.A.9
Miyake, K.10
Golenbock, D.T.11
-
11
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai, Y., S. Akashi, M. Nagafuku, M. Ogata, Y. Iwakura, S. Akira, T. Kitamura, A. Kosugi, M. Kimoto, and K. Miyake. 2002. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3:667.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 667
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
Kitamura, T.7
Kosugi, A.8
Kimoto, M.9
Miyake, K.10
-
12
-
-
0034177888
-
Cutting edge: Cell surface expression and lipopolysaccharide signaling via the Toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages
-
Akashi, S., R. Shimazu, H. Ogata, Y. Nagai, K. Takeda, M. Kimoto, and K. Miyake. 2000. Cutting edge: cell surface expression and lipopolysaccharide signaling via the Toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. J. Immunol. 164:3471.
-
(2000)
J. Immunol.
, vol.164
, pp. 3471
-
-
Akashi, S.1
Shimazu, R.2
Ogata, H.3
Nagai, Y.4
Takeda, K.5
Kimoto, M.6
Miyake, K.7
-
13
-
-
0035851092
-
MD-2 binds to bacterial lipopolysaccharide
-
Viriyakosol, S., P. S. Tobias, R. L. Kitchens, and T. N. Kirkland. 2001. MD-2 binds to bacterial lipopolysaccharide. J. Biol. Chem. 276:38044.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38044
-
-
Viriyakosol, S.1
Tobias, P.S.2
Kitchens, R.L.3
Kirkland, T.N.4
-
14
-
-
0035834135
-
Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4
-
Visintin, A., A. Mazzoni, J. A. Spitzer, and D. M. Segal. 2001. Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4. Proc. Natl. Acad. Sci. USA 98:12156.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12156
-
-
Visintin, A.1
Mazzoni, A.2
Spitzer, J.A.3
Segal, D.M.4
-
15
-
-
0037189544
-
Monomeric recombinant MD-2 binds Toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness
-
Re, F., and J. L. Strominger. 2002. Monomeric recombinant MD-2 binds Toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness. J. Biol. Chem. 277:23427.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23427
-
-
Re, F.1
Strominger, J.L.2
-
16
-
-
0034746813
-
Cutting edge: Gln22 of mouse MD-2 is essential for species-specific lipopolysaccharide mimetic action of Taxol
-
Kawasaki, K., K. Gomi, and M. Nishijima. 2001. Cutting edge: Gln22 of mouse MD-2 is essential for species-specific lipopolysaccharide mimetic action of Taxol. J. Immunol. 166:11.
-
(2001)
J. Immunol.
, vol.166
, pp. 11
-
-
Kawasaki, K.1
Gomi, K.2
Nishijima, M.3
-
17
-
-
0034002247
-
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
-
Lien, E., T. K. Means, H. Heine, A. Yoshimura, S. Kusumoto, K. Fukase, M. J. Fenton, M. Oikawa, N. Qureshi, B. Monks, et al. 2000. Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J. Clin. Invest. 105:497.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 497
-
-
Lien, E.1
Means, T.K.2
Heine, H.3
Yoshimura, A.4
Kusumoto, S.5
Fukase, K.6
Fenton, M.J.7
Oikawa, M.8
Qureshi, N.9
Monks, B.10
-
18
-
-
0034007076
-
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
-
Poltorak, A., P. Ricciardi-Castagnoli, S. Citterio, and B. Beutler. 2000. Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation. Proc. Natl. Acad. Sci. USA 97:2163.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2163
-
-
Poltorak, A.1
Ricciardi-Castagnoli, P.2
Citterio, S.3
Beutler, B.4
-
19
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2
-
da Silva Correia, J., K. Soldau, U. Christen, P. S. Tobias, and R. J. Ulevitch, 2001. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2. J. Biol. Chem. 276:21129.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21129
-
-
Da Silva Correia, J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
20
-
-
0036289969
-
Identification of LPS-binding peptide fragment of MD-2, a Toll-receptor accessory protein
-
Mancek, M., P. Pristovsek, and R. Jerala. 2002. Identification of LPS-binding peptide fragment of MD-2, a Toll-receptor accessory protein. Biochem. Biophys. Res. Commun. 292:880.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.292
, pp. 880
-
-
Mancek, M.1
Pristovsek, P.2
Jerala, R.3
-
21
-
-
0036467447
-
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
-
Bulut, Y., E. Faure, L. Thomas, H. Karahashi, K. S. Michelsen, O. Equils, S. G. Morrison, R. P. Morrison, and M. Arditi. 2002. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J. Immunol. 168:1435.
-
(2002)
J. Immunol.
, vol.168
, pp. 1435
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Karahashi, H.4
Michelsen, K.S.5
Equils, O.6
Morrison, S.G.7
Morrison, R.P.8
Arditi, M.9
-
22
-
-
0033583034
-
Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-I signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
-
Zhang, F. X., C. J. Kirschning, R. Mancinelli, X. P. Xu, Y. Jin, E. Faure. A. Mantovani, M. Rothe, M. Muzio, and M. Arditi. 1999. Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-I signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274:7611.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7611
-
-
Zhang, F.X.1
Kirschning, C.J.2
Mancinelli, R.3
Xu, X.P.4
Jin, Y.5
Faure, E.6
Mantovani, A.7
Rothe, M.8
Muzio, M.9
Arditi, M.10
-
23
-
-
0037220924
-
Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 by alanine-scanning mutagenesis
-
Kawasaki, K., H. Nogawa, and M. Nishijima. 2003. Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 by alanine-scanning mutagenesis. J. Immunol. 170:413.
-
(2003)
J. Immunol.
, vol.170
, pp. 413
-
-
Kawasaki, K.1
Nogawa, H.2
Nishijima, M.3
-
24
-
-
0034650427
-
Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
-
Ohashi, K., V. Burkart, S. Flohe, and H. Kolb. 2000. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J. Immunol. 164:558.
-
(2000)
J. Immunol.
, vol.164
, pp. 558
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
25
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones, E. A., L. Popova, L. Kwinn, L. M. Haynes, L. P. Jones, R. A. Tripp, E. E. Walsh, M. W. Freeman, D. T. Golenbock, L. J. Anderson, and R. W. Finberg. 2000. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1:398.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 398
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
Tripp, R.A.6
Walsh, E.E.7
Freeman, M.W.8
Golenbock, D.T.9
Anderson, L.J.10
Finberg, R.W.11
-
26
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura, Y., M. Watari, E. S. Jerud, D. W. Young, S. T. Ishizaka, J. Rose, J. C. Chow, and J. F. Strauss. III. 2001. The extra domain A of fibronectin activates Toll-like receptor 4. J. Biol. Chem. 276:10229.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10229
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
Young, D.W.4
Ishizaka, S.T.5
Rose, J.6
Chow, J.C.7
Strauss III, J.F.8
|