Laboratory variability does not preclude identification of biological functions impacted by hydroxyurea

Environmental and Molecular Mutagenesis

Volumn 46, Issue 4, 2005, Pages 221-235

  Müller, Arne ^a   Boitier, Eric ^a   Hu, Ting ^b   Carr, Gregory J ^b   Le Fèvre, Anne Céline ^a   Marchandeau, Jean Pierre ^a   Flor, Manoli ^a   Jefferson, Felicia ^c   Aardema, Marilyn J ^b   Thybaud, Véronique ^a  

^a SANOFI   (France)

^b PROCTER AND GAMBLE COMPANY   (United States)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

ANOVA; Dose response; Gene expression; Gene Ontology; Microarray; Regression; Study comparison; Toxicogenomics

Indexed keywords

CASPASE; HYDROXYUREA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; CYTOTOXICITY; DNA METABOLISM; DNA REPAIR; GENE ACTIVITY; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENOMICS; GENOTOXICITY; LABORATORY; LYMPHOCYTE; LYMPHOMA CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; RISK ASSESSMENT; STATISTICAL ANALYSIS; TOXICOGENETICS;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HYDROXYUREA; LABORATORY TECHNIQUES AND PROCEDURES; LEUKEMIA L5178; MICE; MODELS, BIOLOGICAL; MUTAGENICITY TESTS; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 30844442543     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20164     Document Type: Article

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