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Volumn 1, Issue 3, 2003, Pages 441-454

Current and emerging therapeutic approaches to hepatitis C infection

Author keywords

Combination therapy; Hepatitis C virus; Interferon; Pegylated interferon

Indexed keywords

2' BETA METHYLGUANOSINE; 3 [((2 DIPROPYLMINO)ETHYL)THIO] 5H 1,2,4 TRIAZINO[5,6B]INDOLE; ALKOVIR; ALPHA INTERFERON; AMANTADINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIDEPRESSANT AGENT; ANTIVIRUS AGENT; CARBOHYDRATE DERIVATIVE; CILUPREVIR; COMPLEMENTARY RNA; CONSENSUS INTERFERON; CONTRACEPTIVE AGENT; DPC AB914400; GLUCOVIR; HEPTAZYME; ISIS 14803; NM 107; PARACETAMOL; PEGASIS; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; PROTEINASE INHIBITOR; REBETROL; RIBAVIRIN; RIBONUCLEOSIDE DERIVATIVE; RIBOZYME; RNA DIRECTED DNA POLYMERASE INHIBITOR; RNA HELICASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALOPICITABINE; VP 32947; VP 50406; VX 950;

EID: 3042703977     PISSN: 14787210     EISSN: None     Source Type: Journal    
DOI: 10.1586/14787210.1.3.441     Document Type: Review
Times cited : (7)

References (102)
  • 1
    • 0030928695 scopus 로고    scopus 로고
    • Hepatitis C: The clinical spectrum of disease
    • Hoofnagle JH. Hepatitis C: the clinical spectrum of disease. Hepatology 26(3 Suppl. 1), 15S-20S (1997).
    • (1997) Hepatology , vol.26 , Issue.3 SUPPL. 1
    • Hoofnagle, J.H.1
  • 2
    • 1842291578 scopus 로고    scopus 로고
    • The treatment of chronic viral hepatitis
    • Hoofnagle JH, di Bisceglie AM. The treatment of chronic viral hepatitis. N. Engl. J. Med. 1 336(5), 347-356 (1997).
    • (1997) N. Engl. J. Med. 1 , vol.336 , Issue.5 , pp. 347-356
    • Hoofnagle, J.H.1    di Bisceglie, A.M.2
  • 3
    • 0036139972 scopus 로고    scopus 로고
    • New therapeutic strategies for hepatitis C
    • Di Bisceglie AM, McHutchison J, Rice CM. New therapeutic strategies for hepatitis C. Hepatology 35(1), 224-231 (2002).
    • (2002) Hepatology , vol.35 , Issue.1 , pp. 224-231
    • Di Bisceglie, A.M.1    McHutchison, J.2    Rice, C.M.3
  • 4
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood borne non-A, non-B viral hepatitis genome
    • Choo Q, Kuo G, Weiner AJ et al. Isolation of a cDNA clone derived from a blood borne non-A, non-B viral hepatitis genome. Science 244, 359-362 (1989).
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.1    Kuo, G.2    Weiner, A.J.3
  • 5
    • 0036835773 scopus 로고    scopus 로고
    • Hepatitis C virus replicons: Potential role for drug development
    • Bartenschlager R, Hepatitis C virus replicons: potential role for drug development. Nature Rev. Drug Discov. 1(11), 911-916 (2002).
    • (2002) Nature Rev. Drug Discov. , vol.1 , Issue.11 , pp. 911-916
    • Bartenschlager, R.1
  • 6
    • 0033920795 scopus 로고    scopus 로고
    • Replication of hepatitis C virus
    • Bartenschlager R, Lohmann V. Replication of hepatitis C virus. J. Genet. Virol. 81(Pt 7), 1631-1648 (2000).
    • (2000) J. Genet. Virol. , vol.81 , Issue.PART 7 , pp. 1631-1648
    • Bartenschlager, R.1    Lohmann, V.2
  • 7
    • 0036848564 scopus 로고    scopus 로고
    • Interaction of hepatitis C virus proteins with host cell membranes and lipids
    • Dubuisson J, Penin F, Moradpour D. Interaction of hepatitis C virus proteins with host cell membranes and lipids. Trends Cell. Biol. 12(11), 517-523 (2002).
    • (2002) Trends Cell. Biol. , vol.12 , Issue.11 , pp. 517-523
    • Dubuisson, J.1    Penin, F.2    Moradpour, D.3
  • 8
    • 0037416146 scopus 로고    scopus 로고
    • Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
    • Bartosch B, Dubuisson J, Cosset FL. Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes. J. Exp. Med. 197(5), 633-642 (2003).
    • (2003) J. Exp. Med. , vol.197 , Issue.5 , pp. 633-642
    • Bartosch, B.1    Dubuisson, J.2    Cosset, F.L.3
  • 9
    • 0033992596 scopus 로고    scopus 로고
    • Folding, assembly and subcellular localization of hepatitis C virus glycoproteins
    • Dubuisson J, Folding, assembly and subcellular localization of hepatitis C virus glycoproteins. Curr. Top. Microbiol. Immunol. 242, 135-148 (2000).
    • (2000) Curr. Top. Microbiol. Immunol. , vol.242 , pp. 135-148
    • Dubuisson, J.1
  • 10
    • 0035124045 scopus 로고    scopus 로고
    • Bad time for Bonzo? Experimental models of hepatitis C virus infection, replication and pathogenesis
    • Grakoui A, Hanson HL, Rice CM. Bad time for Bonzo? Experimental models of hepatitis C virus infection, replication and pathogenesis. Hepatology 33(3), 489-495 (2001).
    • (2001) Hepatology , vol.33 , Issue.3 , pp. 489-495
    • Grakoui, A.1    Hanson, H.L.2    Rice, C.M.3
  • 11
    • 0032841846 scopus 로고    scopus 로고
    • Pathogenesis of chronic hepatitis C: Immunological features of hepatic injury and viral persistence
    • Cerny A, Chisari FV. Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence. Hepatology 30(3), 595-601 (1999).
    • (1999) Hepatology , vol.30 , Issue.3 , pp. 595-601
    • Cerny, A.1    Chisari, F.V.2
  • 12
    • 0029954252 scopus 로고    scopus 로고
    • Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells
    • de la Torre JC, Mallory M, Brot M et al. Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells. Virology 220(2), 508-515 (1996).
    • (1996) Virology , vol.220 , Issue.2 , pp. 508-515
    • de la Torre, J.C.1    Mallory, M.2    Brot, M.3
  • 13
    • 0025719819 scopus 로고
    • Molecular anatomy of viral persistence
    • Oldstone MB. Molecular anatomy of viral persistence. J. Virol. 65(12), 6381-6386 (1991).
    • (1991) J. Virol. , vol.65 , Issue.12 , pp. 6381-6386
    • Oldstone, M.B.1
  • 14
    • 0031783128 scopus 로고    scopus 로고
    • Hepatitis C virus infection: Virus/host interactions
    • Pawlotsky JM. Hepatitis C virus infection: virus/host interactions. J. Viral Hepatitis 5(Suppl. 1), 3-8 (1998).
    • (1998) J. Viral Hepatitis , vol.5 , Issue.SUPPL. 1 , pp. 3-8
    • Pawlotsky, J.M.1
  • 15
    • 19044396066 scopus 로고    scopus 로고
    • Characterization of low- and very-low-density hepatitis C virus RNA-containing particles
    • Andre P, Komurian-Pradel F, Deforges S et al. Characterization of low- and very-low-density hepatitis C virus RNA-containing particles. J. Virol. 76(14), 6919-6928 (2002).
    • (2002) J. Virol. , vol.76 , Issue.14 , pp. 6919-6928
    • Andre, P.1    Komurian-Pradel, F.2    Deforges, S.3
  • 16
    • 0344563480 scopus 로고    scopus 로고
    • Nonrandom distribution of hepatitis C virus quasispecies in plasma and peripheral blood mononuclear cell subsets
    • Afonso AM, Jiang J, Penin F et al. Nonrandom distribution of hepatitis C virus quasispecies in plasma and peripheral blood mononuclear cell subsets. J. Virol. 73(11), 9213-9221 (1999).
    • (1999) J. Virol. , vol.73 , Issue.11 , pp. 9213-9221
    • Afonso, A.M.1    Jiang, J.2    Penin, F.3
  • 17
    • 0037562850 scopus 로고    scopus 로고
    • Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection
    • Goutagny N, Fatmi A, De Ledinghen V et al. Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection. J. Infect. Dis. 187(12), 1951-1958 (2003).
    • (2003) J. Infect. Dis. , vol.187 , Issue.12 , pp. 1951-1958
    • Goutagny, N.1    Fatmi, A.2    De Ledinghen, V.3
  • 18
    • 0035121503 scopus 로고    scopus 로고
    • Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection
    • Bain C, Fatmi A, Zoulim F et al. Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology 120(2), 512-524 (2001).
    • (2001) Gastroenterology , vol.120 , Issue.2 , pp. 512-524
    • Bain, C.1    Fatmi, A.2    Zoulim, F.3
  • 20
    • 0035000769 scopus 로고    scopus 로고
    • + T-lymphocytes after infection with hepatitis C virus
    • + T-lymphocytes after infection with hepatitis C virus. J. Virol. 75(12), 5550-5558 (2001).
    • (2001) J. Virol. , vol.75 , Issue.12 , pp. 5550-5558
    • Gruener, N.H.1    Lechner, F.2    Jung, M.C.3
  • 21
    • 0037242882 scopus 로고    scopus 로고
    • Clinical consequences of hepatitis C virus infection
    • Zoulim F, Chevallier M, Maynard M et al. Clinical consequences of hepatitis C virus infection. Rev. Med. Virol. 13(1), 57-68 (2003).
    • (2003) Rev. Med. Virol. , vol.13 , Issue.1 , pp. 57-68
    • Zoulim, F.1    Chevallier, M.2    Maynard, M.3
  • 22
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C
    • The OBSVIRC, METAVIR, CLINIVIR and DOSVIRC groups
    • Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR and DOSVIRC groups. Lancet 349(9055), 825-832 (1997).
    • (1997) Lancet , vol.349 , Issue.9055 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 23
    • 0032899215 scopus 로고    scopus 로고
    • High incidence of allograft cirrhosis in hepatitis C virus genotype 1b infection following transplantation: Relationship with rejection episodes
    • Prieto M, Berenguer M, Rayon JM et al. High incidence of allograft cirrhosis in hepatitis C virus genotype 1b infection following transplantation: relationship with rejection episodes. Hepatology 29(1), 250-256 (1999).
    • (1999) Hepatology , vol.29 , Issue.1 , pp. 250-256
    • Prieto, M.1    Berenguer, M.2    Rayon, J.M.3
  • 24
    • 0032080213 scopus 로고    scopus 로고
    • Early development of chronic active hepatitis in recurrent hepatitis C virus infection after liver transplantation: Association with treatment of rejection
    • Berenguer M, Prieto M, Cordoba J et al. Early development of chronic active hepatitis in recurrent hepatitis C virus infection after liver transplantation: association with treatment of rejection. J. Hepatol. 28(5), 756-763 (1998).
    • (1998) J. Hepatol. , vol.28 , Issue.5 , pp. 756-763
    • Berenguer, M.1    Prieto, M.2    Cordoba, J.3
  • 25
    • 0029385852 scopus 로고
    • Natural history of hepatitis C virus infection
    • Marcellin P, Benhamou JP. [Natural history of hepatitis C virus infection]. Pathol. Biol. (Paris), 43(8), 669-673 (1995).
    • (1995) Pathol. Biol. (Paris) , vol.43 , Issue.8 , pp. 669-673
    • Marcellin, P.1    Benhamou, J.P.2
  • 26
    • 84989559703 scopus 로고
    • Hepatitis C virus genotypes: An investigation of type-specific differences in geographic origin and disease
    • Dusheiko G, Schmilovitz-Weiss H, Brown D et al. Hepatitis C virus genotypes: an investigation of type-specific differences in geographic origin and disease. Hepatology 19, 13-18 (1994).
    • (1994) Hepatology , vol.19 , pp. 13-18
    • Dusheiko, G.1    Schmilovitz-Weiss, H.2    Brown, D.3
  • 27
    • 0035009810 scopus 로고    scopus 로고
    • Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis C
    • Poynard T, Ratziu V, Charlotte F et al. Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis C. J. Hepatol. 34(5), 730-739 (2001).
    • (2001) J. Hepatol. , vol.34 , Issue.5 , pp. 730-739
    • Poynard, T.1    Ratziu, V.2    Charlotte, F.3
  • 28
    • 0033844251 scopus 로고    scopus 로고
    • 2b and ribavirin in chronic hepatitis C
    • The Hepatitis C Intervention Therapy Group
    • 2b and ribavirin in chronic hepatitis C. The Hepatitis C Intervention Therapy Group. Hepatology 32(3), 647-653 (2000).
    • (2000) Hepatology , vol.32 , Issue.3 , pp. 647-653
    • Glue, P.1    Rouzier-Panis, R.2    Raffanel, C.3
  • 29
    • 17844403232 scopus 로고    scopus 로고
    • 2b as initial treatment for chronic hepatitis C
    • 2b as initial treatment for chronic hepatitis C. Hepatology 34(2), 395-403 (2001).
    • (2001) Hepatology , vol.34 , Issue.2 , pp. 395-403
    • Lindsay, K.L.1    Trepo, C.2    Heintges, T.3
  • 31
    • 0034619946 scopus 로고    scopus 로고
    • 2a in patients with chronic hepatitis C
    • 2a in patients with chronic hepatitis C. N. Engl. J. Med. 343(23), 1666-1672 (2000).
    • (2000) N. Engl. J. Med. , vol.343 , Issue.23 , pp. 1666-1672
    • Zeuzem, S.1
  • 32
    • 0035934568 scopus 로고    scopus 로고
    • 2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • 2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 358(9286), 958-965 (2001).
    • (2001) Lancet , vol.358 , Issue.9286 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 33
    • 0037179698 scopus 로고    scopus 로고
    • 2a plus ribavirin for chronic hepatitis C virus infection
    • 2a plus ribavirin for chronic hepatitis C virus infection. N. Engl. J. Med. 347(13), 975-982 (2002).
    • (2002) N. Engl. J. Med. , vol.347 , Issue.13 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 34
    • 0001474935 scopus 로고    scopus 로고
    • 2a (40kD) (PEGASYS) in combination with ribavirin (RBV): Efficacy and safety results from a Phase III, randomized, double-blind multicentre study examining effect of durationof treatment and RBV dose
    • 2a (40kD) (PEGASYS) in combination with ribavirin (RBV): efficacy and safety results from a Phase III, randomized, double-blind multicentre study examining effect of durationof treatment and RBV dose. J. Hepatol. 36(1 Suppl. 3), 17-18 (2002).
    • (2002) J. Hepatol. , vol.36 , Issue.1 SUPPL. 3 , pp. 17-18
    • Hadziyannis, S.J.1
  • 35
    • 0033760016 scopus 로고    scopus 로고
    • Hepatitis C virus resistance to antiviral therapy
    • Pawlotsky JM. Hepatitis C virus resistance to antiviral therapy. Hepatology 32(5), 889-896 (2000).
    • (2000) Hepatology , vol.32 , Issue.5 , pp. 889-896
    • Pawlotsky, J.M.1
  • 36
    • 0032585237 scopus 로고    scopus 로고
    • 2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus
    • International Hepatitis Interventional Therapy Group (IHIT) [see comments]
    • 2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT) [see comments]. Lancet 352(9138), 1426-1432 (1998).
    • (1998) Lancet , vol.352 , Issue.9138 , pp. 1426-1432
    • Poynard, T.1
  • 37
    • 0033024781 scopus 로고    scopus 로고
    • Ribavirin polarizes human T-cell responses towards a Type 1 cytokine profile
    • Tam RC, Pai B, Bard J et al. Ribavirin polarizes human T-cell responses towards a Type 1 cytokine profile. J. Hepatol. 30(3), 376-382 (1999).
    • (1999) J. Hepatol. , vol.30 , Issue.3 , pp. 376-382
    • Tam, R.C.1    Pai, B.2    Bard, J.3
  • 38
    • 0031663638 scopus 로고    scopus 로고
    • The antiviral compound ribavirin modulates the T-helper (Th) 1/Th2 subset balance in hepatitis B and C virus-specific immune responses
    • Hultgren C, Milich DR, Weiland O et al. The antiviral compound ribavirin modulates the T-helper (Th) 1/Th2 subset balance in hepatitis B and C virus-specific immune responses. J. Genet. Virol. 79(Pt 10), 2381-2391 (1998).
    • (1998) J. Genet. Virol. , vol.79 , Issue.PART 10 , pp. 2381-2391
    • Hultgren, C.1    Milich, D.R.2    Weiland, O.3
  • 39
    • 0034864550 scopus 로고    scopus 로고
    • Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes
    • Lanford RE, Chavez D, Guerra B et al. Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes. J. Virol. 75(17), 8074-8081 (2001).
    • (2001) J. Virol. , vol.75 , Issue.17 , pp. 8074-8081
    • Lanford, R.E.1    Chavez, D.2    Guerra, B.3
  • 40
    • 0035076685 scopus 로고    scopus 로고
    • Evolution of hepatitis C virus genome in chronically infected patients receiving ribavirin monotherapy
    • Querenghi F, Yu Q, Billaud G et al. Evolution of hepatitis C virus genome in chronically infected patients receiving ribavirin monotherapy. J. Viral Hepatitis 8(2), 120-131 (2001).
    • (2001) J. Viral Hepatitis , vol.8 , Issue.2 , pp. 120-131
    • Querenghi, F.1    Yu, Q.2    Billaud, G.3
  • 41
    • 0032475822 scopus 로고    scopus 로고
    • Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-α therapy
    • Neumann AU, Lam NP, Dahari H et al. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-α therapy. Science 282(5386), 103-107 (1998).
    • (1998) Science , vol.282 , Issue.5386 , pp. 103-107
    • Neumann, A.U.1    Lam, N.P.2    Dahari, H.3
  • 43
    • 0031807791 scopus 로고    scopus 로고
    • Hepatitis C virus dynamics in vivo: Effect of ribavirin and interferon-α on viral turnover
    • Zeuzem S, Schmidt JM, Lee JH et al. Hepatitis C virus dynamics in vivo: effect of ribavirin and interferon-α on viral turnover. Hepatology 28(1), 245-252 (1998).
    • (1998) Hepatology , vol.28 , Issue.1 , pp. 245-252
    • Zeuzem, S.1    Schmidt, J.M.2    Lee, J.H.3
  • 44
    • 0034888396 scopus 로고    scopus 로고
    • Effect of interferon-α on the hepatitis C virus replicon
    • Guo JT, Bichko VV, Seeger C. Effect of interferon-α on the hepatitis C virus replicon. J. Virol. 75(18), 8516-8523 (2001).
    • (2001) J. Virol. , vol.75 , Issue.18 , pp. 8516-8523
    • Guo, J.T.1    Bichko, V.V.2    Seeger, C.3
  • 45
    • 0032547944 scopus 로고    scopus 로고
    • 2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C
    • International Hepatitis Interventional Therapy Group [see comments]
    • 2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group [see comments]. N. Engl. J. Med. 339(21), 1493-1499 (1998).
    • (1998) N. Engl. J. Med. , vol.339 , Issue.21 , pp. 1493-1499
    • Davis, G.L.1    Esteban-Mur, R.2    Rustgi, V.3
  • 46
    • 0036242165 scopus 로고    scopus 로고
    • 2b and ribavirin on liver fibrosis in patients with chronic hepatitis C
    • 2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 122(5), 1303-1313 (2002).
    • (2002) Gastroenterology , vol.122 , Issue.5 , pp. 1303-1313
    • Poynard, T.1    McHutchison, J.2    Manns, M.3
  • 47
    • 0033766167 scopus 로고    scopus 로고
    • 2b and ribavirin on progression of liver fibrosis in patients with chronic hepatitis C
    • 2b and ribavirin on progression of liver fibrosis in patients with chronic hepatitis C. Hepatology 32(5), 1131-1137 (2000).
    • (2000) Hepatology , vol.32 , Issue.5 , pp. 1131-1137
    • Poynard, T.1    McHutchison, J.2    Manns, M.3
  • 48
    • 0037372609 scopus 로고    scopus 로고
    • 2b plus ribavirin for initial treatment of chronic hepatitis C
    • 2b plus ribavirin for initial treatment of chronic hepatitis C. Gut 52(3), 425-432 (2003).
    • (2003) Gut , vol.52 , Issue.3 , pp. 425-432
    • Siebert, U.1    Sroczynski, G.2    Rossol, S.3
  • 49
    • 0034124763 scopus 로고    scopus 로고
    • 2b alone or with ribavirin as initial treatment of chronic hepatitis C
    • International Hepatitis Interventional Therapy Group
    • 2b alone or with ribavirin as initial treatment of chronic hepatitis C. International Hepatitis Interventional Therapy Group. Am. J. Gastroenterol. 95(6), 1524-1530 (2000).
    • (2000) Am. J. Gastroenterol. , vol.95 , Issue.6 , pp. 1524-1530
    • Wong, J.B.1    Nevens, F.2
  • 50
    • 0028313993 scopus 로고
    • 2a therapy in cryoglobulinemia associated with hepatitis C virus
    • 2a therapy in cryoglobulinemia associated with hepatitis C virus. N. Engl. J. Med. 330(11), 751-756 (1994).
    • (1994) N. Engl. J. Med. , vol.330 , Issue.11 , pp. 751-756
    • Misiani, R.1    Bellavita, P.2    Fenili, D.3
  • 51
    • 0037063113 scopus 로고    scopus 로고
    • Regression of splenic lymphoma with villous lymphocytes after treatment of hepatitis C virus infection
    • Hermine O, Lefrere F, Bronowicki JP et al. Regression of splenic lymphoma with villous lymphocytes after treatment of hepatitis C virus infection. N. Engl. J. Med. 347, 891-94 (2002).
    • (2002) N. Engl. J. Med. , vol.347 , pp. 891-894
    • Hermine, O.1    Lefrere, F.2    Bronowicki, J.P.3
  • 52
    • 0038183828 scopus 로고    scopus 로고
    • Interferon-ribavirin in association with stavudine has no impact on plasma human immunodeficiency virus (HIV) Type 1 level in patients coinfected with hiv and hepatitis c virus: A CORIST-ANRS HC1 trial
    • Salmon-Ceron D, Lassalle R, Pruvost A et al. Interferon-ribavirin in association with stavudine has no impact on plasma human immunodeficiency virus (HIV) Type 1 level in patients coinfected with hiv and hepatitis c virus: A CORIST-ANRS HC1 trial. Clin. Infect. Dis. 36(10), 1295-1304 (2003).
    • (2003) Clin. Infect. Dis. , vol.36 , Issue.10 , pp. 1295-1304
    • Salmon-Ceron, D.1    Lassalle, R.2    Pruvost, A.3
  • 53
    • 0038555663 scopus 로고    scopus 로고
    • 2b plus ribavirin as therapy for chronic hepatitis C in HIV-infected patients
    • 2b plus ribavirin as therapy for chronic hepatitis C in HIV-infected patients. AIDS 17(7), 1023-1028 (2003).
    • (2003) AIDS , vol.17 , Issue.7 , pp. 1023-1028
    • Perez-Olmeda, M.1    Nunez, M.2    Romero, M.3
  • 55
    • 0038575483 scopus 로고    scopus 로고
    • Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance
    • Gerlach JT, Diepolder HM, Zachoval R et al. Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance. Gastroenterology 125(1), 80-88 (2003).
    • (2003) Gastroenterology , vol.125 , Issue.1 , pp. 80-88
    • Gerlach, J.T.1    Diepolder, H.M.2    Zachoval, R.3
  • 56
    • 0344716597 scopus 로고    scopus 로고
    • 2b plus ribavirin: Study of sixteen patients
    • 2b plus ribavirin: study of sixteen patients]. Gastroenterol. Clin. Biol. 27(3), 294-299 (2003).
    • (2003) Gastroenterol. Clin. Biol. , vol.27 , Issue.3 , pp. 294-299
    • Rocca, J.1
  • 57
    • 20644455767 scopus 로고    scopus 로고
    • Chronic hepatitis C virus patients with breakthroughs during interferon treatment can successfully be retreated with consensus interferon
    • The Consensus Interferon Study Group
    • Heathcote EJ, James S, Mullen KD et al. Chronic hepatitis C virus patients with breakthroughs during interferon treatment can successfully be retreated with consensus interferon. The Consensus Interferon Study Group. Hepatology 30(2), 562-566 (1999).
    • (1999) Hepatology , vol.30 , Issue.2 , pp. 562-566
    • Heathcote, E.J.1    James, S.2    Mullen, K.D.3
  • 58
    • 0036923777 scopus 로고    scopus 로고
    • Retreatment with interferon-β of patients with chronic hepatitis C virus infection
    • Pellicano R, Palmas F, Cariti G et al. Retreatment with interferon-β of patients with chronic hepatitis C virus infection. Eur. J. Gastroenterol. Hepatol. 14(12), 1377-1382 (2002).
    • (2002) Eur. J. Gastroenterol. Hepatol. , vol.14 , Issue.12 , pp. 1377-1382
    • Pellicano, R.1    Palmas, F.2    Cariti, G.3
  • 59
    • 0036838695 scopus 로고    scopus 로고
    • Comparative analysis of antihepatitis C virus activity and gene expression mediated by α-, β- and γ- interferons
    • Cheney IW, Lai VC, Zhong W et al. Comparative analysis of antihepatitis C virus activity and gene expression mediated by α-, β- and γ- interferons. J. Virol. 76(21), 11148-11154 (2002).
    • (2002) J. Virol. , vol.76 , Issue.21 , pp. 11148-11154
    • Cheney, I.W.1    Lai, V.C.2    Zhong, W.3
  • 60
    • 0037228023 scopus 로고    scopus 로고
    • Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha and ribavirin in hepatitis C virus subgenomic replicons
    • Lanford RE, Guerra B, Lee H et al. Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha and ribavirin in hepatitis C virus subgenomic replicons. J. Virol. 77(2), 1092-1104 (2003).
    • (2003) J. Virol. , vol.77 , Issue.2 , pp. 1092-1104
    • Lanford, R.E.1    Guerra, B.2    Lee, H.3
  • 61
    • 0038703409 scopus 로고    scopus 로고
    • Gene expression profiling of the cellular transcriptional network regulated by interferon-α/β and its partial attenuation by the hepatitis C virus nonstructural 5A protein
    • Geiss GK, Carter VS, He Y et al. Gene expression profiling of the cellular transcriptional network regulated by interferon-α /β and its partial attenuation by the hepatitis C virus nonstructural 5A protein. J. Virol. 77(11), 6367-6375 (2003).
    • (2003) J. Virol. , vol.77 , Issue.11 , pp. 6367-6375
    • Geiss, G.K.1    Carter, V.S.2    He, Y.3
  • 62
    • 0038185313 scopus 로고    scopus 로고
    • Gene expression associated with interferon-α antiviral activity in an HCV replicon cell line
    • Zhu H, Zhao H, Collins CD et al. Gene expression associated with interferon-α antiviral activity in an HCV replicon cell line. Hepatology 37(5), 1180-1188 (2003).
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1180-1188
    • Zhu, H.1    Zhao, H.2    Collins, C.D.3
  • 63
    • 0027193740 scopus 로고
    • Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro
    • Shimizu YK, Purcell RH, Yoshikura H. Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro. Proc. Natl Acad. Sci. USA 90(13), 6037-6041 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , Issue.13 , pp. 6037-6041
    • Shimizu, Y.K.1    Purcell, R.H.2    Yoshikura, H.3
  • 64
    • 0033020469 scopus 로고    scopus 로고
    • Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus
    • Major ME, Mihalik K, Fernandez J et al. Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus. J. Virol. 73(4), 3317-3325 (1999).
    • (1999) J. Virol. , vol.73 , Issue.4 , pp. 3317-3325
    • Major, M.E.1    Mihalik, K.2    Fernandez, J.3
  • 65
    • 12644289313 scopus 로고    scopus 로고
    • Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein
    • Farci P, Shimoda A, Wong D et al. Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein. PG. Proc. Natl Acad. Sci. USA 93(26) (1996).
    • (1996) PG. Proc. Natl. Acad. Sci. USA , vol.93 , Issue.26
    • Farci, P.1    Shimoda, A.2    Wong, D.3
  • 66
    • 0026767691 scopus 로고
    • Lack of protective immunity against reinfection with hepatitis C virus
    • Farci P, Alter HJ, Govindarajan S et al. Lack of protective immunity against reinfection with hepatitis C virus. Science 258(5079), 135-140 (1992).
    • (1992) Science , vol.258 , Issue.5079 , pp. 135-140
    • Farci, P.1    Alter, H.J.2    Govindarajan, S.3
  • 67
    • 0030864915 scopus 로고    scopus 로고
    • Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA
    • Kolykhalov AA, Agapov EV, Blight KJ et al. Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 277(5325), 570-574 (1997).
    • (1997) Science , vol.277 , Issue.5325 , pp. 570-574
    • Kolykhalov, A.A.1    Agapov, E.V.2    Blight, K.J.3
  • 68
    • 0037080355 scopus 로고    scopus 로고
    • The hepatitis C virus (HCV) - Trimera mouse: A model for evaluation of agents against HCV
    • Ilan E, Arazi J, Nussbaum O et al. The hepatitis C virus (HCV) - Trimera mouse: a model for evaluation of agents against HCV. J. Infect. Dis. 185(2), 153-161 (2002).
    • (2002) J. Infect. Dis. , vol.185 , Issue.2 , pp. 153-161
    • Ilan, E.1    Arazi, J.2    Nussbaum, O.3
  • 69
    • 0038137413 scopus 로고    scopus 로고
    • Therapeutic antibodies against viral hepatitis
    • Dagan S, Eren R. Therapeutic antibodies against viral hepatitis. Curr. Opin. Mol. Ther. 5(2), 148-155 (2003).
    • (2003) Curr. Opin. Mol. Ther. , vol.5 , Issue.2 , pp. 148-155
    • Dagan, S.1    Eren, R.2
  • 70
    • 17944379233 scopus 로고    scopus 로고
    • Hepatitis C virus replication in mice with chimeric human livers
    • Mercer DF, Schiller DE, Elliott JF et al. Hepatitis C virus replication in mice with chimeric human livers. Nature Med. 7(8), 927-933 (2001).
    • (2001) Nature Med. , vol.7 , Issue.8 , pp. 927-933
    • Mercer, D.F.1    Schiller, D.E.2    Elliott, J.F.3
  • 71
    • 0032694353 scopus 로고    scopus 로고
    • Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum antihepatitis virus agents
    • Zitzmann N, Mehta AS, Carrouee S et al. Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum antihepatitis virus agents. Proc. Natl Acad. Sci. USA 96(21), 11878-11882 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , Issue.21 , pp. 11878-11882
    • Zitzmann, N.1    Mehta, A.S.2    Carrouee, S.3
  • 72
    • 0034849492 scopus 로고    scopus 로고
    • Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus
    • Durantel D, Branza-Nichita N, Carrouee-Durantel S et al. Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus. J. Virol. 75(19), 8987-8998 (2001).
    • (2001) J. Virol. , vol.75 , Issue.19 , pp. 8987-8998
    • Durantel, D.1    Branza-Nichita, N.2    Carrouee-Durantel, S.3
  • 73
    • 0035208060 scopus 로고    scopus 로고
    • Host range studies of GB virus-B hepatitis agent, the closest relative of hepatitis C virus, in New World monkeys and chimpanzees
    • Bukh J, Apgar CL, Govindarajan S et al. Host range studies of GB virus-B hepatitis agent, the closest relative of hepatitis C virus, in New World monkeys and chimpanzees. J. Med. Virol. 65(4) 694-697 (2001).
    • (2001) J. Med. Virol. , vol.65 , Issue.4 , pp. 694-697
    • Bukh, J.1    Apgar, C.L.2    Govindarajan, S.3
  • 74
    • 0034466886 scopus 로고    scopus 로고
    • Development of a primary tamarin hepatocyte culture system for GB virus-B: A surrogate model for hepatitis C virus
    • Beames B, Chavez D, Guerra B et al. Development of a primary tamarin hepatocyte culture system for GB virus-B: a surrogate model for hepatitis C virus. J. Virol. 74(24) 11764-11772 (2000).
    • (2000) J. Virol. , vol.74 , Issue.24 , pp. 11764-11772
    • Beames, B.1    Chavez, D.2    Guerra, B.3
  • 75
    • 0037300878 scopus 로고    scopus 로고
    • New therapies on the horizon for hepatitis C: Are we close?
    • De Francesco R, Rice CM. New therapies on the horizon for hepatitis C: are we close? Clin. Liver Dis. 7(1), 211-242 (2003).
    • (2003) Clin. Liver Dis. , vol.7 , Issue.1 , pp. 211-242
    • De Francesco, R.1    Rice, C.M.2
  • 76
    • 0036255277 scopus 로고    scopus 로고
    • New therapies for the treatment of chronic hepatitis C
    • Ideo G, Bellobuono A. New therapies for the treatment of chronic hepatitis C. Curr. Pharm. Des. 8(11), 959-966 (2002).
    • (2002) Curr. Pharm. Des. , vol.8 , Issue.11 , pp. 959-966
    • Ideo, G.1    Bellobuono, A.2
  • 77
    • 0036091674 scopus 로고    scopus 로고
    • Advances in hepatitis C: What is coming in the next 5 years?
    • Locarnini SA, Bartholomeusz A. Advances in hepatitis C: what is coming in the next 5 years? J. Gastroenterol. Hepatol. 17(4), 442-447 (2002).
    • (2002) J. Gastroenterol. Hepatol. , vol.17 , Issue.4 , pp. 442-447
    • Locarnini, S.A.1    Bartholomeusz, A.2
  • 78
    • 0036830350 scopus 로고    scopus 로고
    • Future therapy of hepatitis C
    • McHutchison JG, Patel K. Future therapy of hepatitis C. Hepatology 36(5 Suppl. 1), S245-S252 (2002).
    • (2002) Hepatology , vol.36 , Issue.5 SUPPL. 1
    • McHutchison, J.G.1    Patel, K.2
  • 79
    • 0031658923 scopus 로고    scopus 로고
    • The 3′-untranslated region of hepatitis C virus RNA enhances translation from an internal ribosomal entry site
    • Ito T, Tahara SM, and Lai MM. The 3′-untranslated region of hepatitis C virus RNA enhances translation from an internal ribosomal entry site. J. Virol. 72(11), 8789-8796 (1998).
    • (1998) J. Virol. , vol.72 , Issue.11 , pp. 8789-8796
    • Ito, T.1    Tahara, S.M.2    Lai, M.M.3
  • 80
    • 0035182631 scopus 로고    scopus 로고
    • ISIS-14803 (Isis Pharmaceuticals)
    • Witherell GW. ISIS-14803 (Isis Pharmaceuticals). Curr. Opin. Investig. Drugs 2(11), 1523-1529 (2001).
    • (2001) Curr. Opin. Investig. Drugs , vol.2 , Issue.11 , pp. 1523-1529
    • Witherell, G.W.1
  • 81
    • 0034944233 scopus 로고    scopus 로고
    • Hepatitis C IRES: Translating translation into a therapeutic target
    • Jubin R. Hepatitis C IRES: translating translation into a therapeutic target. Curr. Opin. Mol. Ther. 3(3), 278-287 (2001).
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , Issue.3 , pp. 278-287
    • Jubin, R.1
  • 82
    • 10744230911 scopus 로고    scopus 로고
    • Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs
    • Yokota T, Sakamoto N, Enomoto N et al. Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO Rep. 4(6), 602-608 (2003).
    • (2003) EMBO Rep. , vol.4 , Issue.6 , pp. 602-608
    • Yokota, T.1    Sakamoto, N.2    Enomoto, N.3
  • 83
    • 0037452625 scopus 로고    scopus 로고
    • Interference of hepatitis C virus RNA replication by short interfering RNAs
    • Kapadia SB, Brideau-Andersen A, Chisari FV. Interference of hepatitis C virus RNA replication by short interfering RNAs. Proc. Natl Acad. Sci. USA 100(4), 2014-2018 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.4 , pp. 2014-2018
    • Kapadia, S.B.1    Brideau-Andersen, A.2    Chisari, F.V.3
  • 84
    • 0037315296 scopus 로고    scopus 로고
    • Recent developments in the discovery of hepatitis C virus serine protease inhibitors-towards a new class of antiviral agents?
    • Narjes F, Koch U, Steinkuhler C. Recent developments in the discovery of hepatitis C virus serine protease inhibitors-towards a new class of antiviral agents? Expert Opin. Investig. Drugs 12(2), 153-163 (2003).
    • (2003) Expert Opin. Investig. Drugs , vol.12 , Issue.2 , pp. 153-163
    • Narjes, F.1    Koch, U.2    Steinkuhler, C.3
  • 85
    • 0033992657 scopus 로고    scopus 로고
    • Structure and function of the hepatitis C virus NS3-NS4A serine proteinase
    • De Francesco R, Steinkuhler C. Structure and function of the hepatitis C virus NS3-NS4A serine proteinase. Curr. Top. Microbiol. Immunol. 242, 149-169 (2000).
    • (2000) Curr. Top. Microbiol. Immunol. , vol.242 , pp. 149-169
    • De Francesco, R.1    Steinkuhler, C.2
  • 86
    • 0038165472 scopus 로고    scopus 로고
    • An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA
    • Pause A, Kukolj G, Bailey M et al. An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA. J. Biol. Chem. 278(22), 20374-20380 (2003).
    • (2003) J. Biol. Chem. , vol.278 , Issue.22 , pp. 20374-20380
    • Pause, A.1    Kukolj, G.2    Bailey, M.3
  • 87
    • 0033992576 scopus 로고    scopus 로고
    • Structure and function of hepatitis C virus NS3 helicase
    • Kwong AD, Kim JL, Lin C. Structure and function of hepatitis C virus NS3 helicase. Curr. Top. Microbiol. Immunol. 242, 171-196 (2000).
    • (2000) Curr. Top. Microbiol. Immunol. , vol.242 , pp. 171-196
    • Kwong, A.D.1    Kim, J.L.2    Lin, C.3
  • 88
    • 0032876683 scopus 로고    scopus 로고
    • Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
    • Lesburg CA, Cable MB, Ferrari E et al. Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nature Struct. Biol. 6(10), 937-943 (1999).
    • (1999) Nature Struct. Biol. , vol.6 , Issue.10 , pp. 937-943
    • Lesburg, C.A.1    Cable, M.B.2    Ferrari, E.3
  • 89
    • 0036194639 scopus 로고    scopus 로고
    • Oligomerization and co-operative RNA synthesis activity of hepatitis C virus RNA-dependent RNA polymerase
    • Wang QM, Hockman MA, Staschke K et al. Oligomerization and co-operative RNA synthesis activity of hepatitis C virus RNA-dependent RNA polymerase. J. Virol. 76(8), 3865-3872 (2002).
    • (2002) J. Virol. , vol.76 , Issue.8 , pp. 3865-3872
    • Wang, Q.M.1    Hockman, M.A.2    Staschke, K.3
  • 90
    • 0038707388 scopus 로고    scopus 로고
    • Hepatitis C virus therapies: Current treatments, targets and future perspectives
    • Walker MP, Appleby TC, Zhong W et al. Hepatitis C virus therapies: current treatments, targets and future perspectives. Antiviral Chem. Chemother. 14(1), 1-21 (2003).
    • (2003) Antiviral Chem. Chemother. , vol.14 , Issue.1 , pp. 1-21
    • Walker, M.P.1    Appleby, T.C.2    Zhong, W.3
  • 91
    • 0037367315 scopus 로고    scopus 로고
    • Approaching a new era for hepatitis C virus therapy: Inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase
    • De Francesco R, Tomei L, Altamura S, Summa V, Migliaccio G. Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase. Antiviral Res. 58(1), 1-16 (2003).
    • (2003) Antiviral Res. , vol.58 , Issue.1 , pp. 1-16
    • De Francesco, R.1    Tomei, L.2    Altamura, S.3    Summa, V.4    Migliaccio, G.5
  • 93
    • 0037809239 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs
    • Carroll SS, Tomassini JE, Bosserman M et al. Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs. J. Biol. Chem. 278(14), 11979-11984 (2003).
    • (2003) J. Biol. Chem. , vol.278 , Issue.14 , pp. 11979-11984
    • Carroll, S.S.1    Tomassini, J.E.2    Bosserman, M.3
  • 94
    • 12244305605 scopus 로고    scopus 로고
    • Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture
    • Stuyver LJ, Whitaker T, McBrayer TR et al. Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture. Antimicrob. Agents Chemother. 47(1), 244-254 (2003).
    • (2003) Antimicrob. Agents Chemother. , vol.47 , Issue.1 , pp. 244-254
    • Stuyver, L.J.1    Whitaker, T.2    McBrayer, T.R.3
  • 95
    • 0035824671 scopus 로고    scopus 로고
    • Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin
    • Maag D, Castro C, Hong Z, Cameron CE et al. Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin. J. Biol. Chem 276(49), 46094-46098 (2001).
    • (2001) J. Biol. Chem , vol.276 , Issue.49 , pp. 46094-46098
    • Maag, D.1    Castro, C.2    Hong, Z.3    Cameron, C.E.4
  • 96
    • 0038322074 scopus 로고    scopus 로고
    • Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition
    • Wang M. Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition. J. Biol. Chem. 278(11), 9489-9495 (2003).
    • (2003) J. Biol. Chem. , vol.278 , Issue.11 , pp. 9489-9495
    • Wang, M.1
  • 97
    • 0036200412 scopus 로고    scopus 로고
    • Selection of RNA aptamers that are specific and high-affinity ligands of the hepatitis C virus RNA-dependent RNA polymerase
    • Biroccio A, Hamm J, Incitri I et al. Selection of RNA aptamers that are specific and high-affinity ligands of the hepatitis C virus RNA-dependent RNA polymerase. J. Virol. 76(8), 3688-3696 (2000).
    • (2000) J. Virol. , vol.76 , Issue.8 , pp. 3688-3696
    • Biroccio, A.1    Hamm, J.2    Incitri, I.3
  • 98
    • 0037064091 scopus 로고    scopus 로고
    • Identification and biological characterization of heterocyclic inhibitors of the hepatitis C virus RNA-dependent RNA polymerase
    • Dhanak D, Duffy KJ, Johnston VK et al. Identification and biological characterization of heterocyclic inhibitors of the hepatitis C virus RNA-dependent RNA polymerase. J. Biol. Chem. 277(41), 38322-38327 (2002).
    • (2002) J. Biol. Chem. , vol.277 , Issue.41 , pp. 38322-38327
    • Dhanak, D.1    Duffy, K.J.2    Johnston, V.K.3
  • 99
    • 0038269108 scopus 로고    scopus 로고
    • Arresting initiation of hepatitis C virus RNA synthesis using heterocyclic derivatives
    • Gu B, Johnston VK, Gutshall LL et al. Arresting initiation of hepatitis C virus RNA synthesis using heterocyclic derivatives. J. Biol. Chem. 278(19), 16602-16607 (2003).
    • (2003) J. Biol. Chem. , vol.278 , Issue.19 , pp. 16602-16607
    • Gu, B.1    Johnston, V.K.2    Gutshall, L.L.3
  • 100
    • 0037016676 scopus 로고    scopus 로고
    • Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase
    • Moradpour D, Bieck E, Hugle T et al. Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase. J. Biol. Chem. 277(1), 593-601 (2002).
    • (2002) J. Biol. Chem. , vol.277 , Issue.1 , pp. 593-601
    • Moradpour, D.1    Bieck, E.2    Hugle, T.3
  • 101
    • 0038284830 scopus 로고    scopus 로고
    • The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives
    • Pavlovic D, Neville DC, Argaud O et al. The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives. Proc. Natl Acad. Sci. USA 100(10), 6104-618 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.10 , pp. 6104-6618
    • Pavlovic, D.1    Neville, D.C.2    Argaud, O.3
  • 102
    • 0037472806 scopus 로고    scopus 로고
    • The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine
    • Griffin SD, Beales LP, Clarke DS et al. The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine. FEBS Lett. 535(1-3), 34-38 (2003).
    • (2003) FEBS Lett. , vol.535 , Issue.1-3 , pp. 34-38
    • Griffin, S.D.1    Beales, L.P.2    Clarke, D.S.3


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