An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA

Journal of Biological Chemistry

Volumn 278, Issue 22, 2003, Pages 20374-20380

  Pause, Arnim ^b   Kukolj, George ^a   Bailey, Murray ^a   Brault, Martine ^a   Dô, Florence ^a   Halmos, Ted ^a   Lagacé, Lisette ^a   Maurice, Roger ^a   Marquis, Martin ^a   McKercher, Ginette ^a   Pellerin, Charles ^a   Pilote, Louise ^a   Thibeault, Diane ^a   Lamarrell, Daniel ^a  

^a Boehringer Ingelheim Canada   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DRUG PRODUCTS; ENZYME INHIBITION; PROTEINS; RNA;

ANTIVIRAL DRUGS;

VIRUSES;

ANTIVIRUS AGENT; GAMMA INTERFERON; NS3 PROTEASE; NS3 PROTEASE INHIBITOR; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VIRUS RNA; ALPHA INTERFERON; NS3 PROTEIN, HEPATITIS C VIRUS; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG RESEARCH; ENZYME ACTIVITY; HALF LIFE TIME; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; REPLICON; VIRUS REPLICATION; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; HEPATITIS C;

HEPATITIS C VIRUS; RNA VIRUSES;

ANTIVIRAL AGENTS; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERFERON-ALPHA; RNA, VIRAL; SERINE PROTEINASE INHIBITORS; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0038165472     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210785200     Document Type: Article

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