MGLuR5 activation reduces β-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor

Journal of Neurochemistry

Volumn 89, Issue 6, 2004, Pages 1528-1536

  Movsesyan, Vilen A ^a   Stoica, Bogdan A ^a   Faden, Alan I ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

amyloid; Group I mGluR; Neuronal apoptosis

Indexed keywords

2 CHLORO 5 HYDROXYPHENYLGLYCINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[25-35]; APOPTOSIS INDUCING FACTOR; CASPASE; CASPASE 3; CYTOCHROME C; ETOPOSIDE; LACTATE DEHYDROGENASE; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; MITOCHONDRIAL PROTEIN; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME RELEASE; EXPOSURE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RECEPTOR UPREGULATION;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASES; CELLS, CULTURED; CEREBRAL CORTEX; CYTOCHROMES C; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FLAVOPROTEINS; GLYCINE; MEMBRANE PROTEINS; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PHENYLACETATES; PROTEIN TRANSPORT; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; UP-REGULATION;

ANIMALIA;

EID: 3042662255     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02451.x     Document Type: Article

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