mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 1, 2001, Pages 41-47

  Movsesyan, Vilen A ^a   O'Leary, Deirdre M ^a   Fan, Lei ^a   Bao, Weili ^a   Mullins, Paul G M ^a   Knoblach, Susan M ^a   Faden, Alan I ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; METABOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN INJURY; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; MALE; NERVE INJURY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN INJURIES; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HYDROLYSIS; MALE; MAZE LEARNING; MEMORY; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOLS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0035197286     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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