Folate deficiency induces aneuploidy in human lymphocytes in vitro - Evidence using cytokinesis-blocked cells and probes specific for chromosomes 17 and 21

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 551, Issue 1-2, 2004, Pages 167-180

  Wang, Xu ^a,b   Thomas, Philip ^c   Xue, Jinglun ^a   Fenech, Michael ^c  

^a FUDAN UNIVERSITY   (China)

^b YUNNAN NORMAL UNIVERSITY   (China)

^c CSIRO   (Australia)

Author keywords

5 methyltetrahydrofolate; 5 Methyltetrahydrofolate; Aneuploidy; binucleated; BN; Chromosome 17; Chromosome 21; FA; FISH; fluorescent in situ hybridization; Folic acid; folic acid; MF; MONO; mononucleated

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; BIOTIN; DIGOXIGENIN; FOLIC ACID;

ADULT; ANEUPLOIDY; ARTICLE; CELL CULTURE; CELL NUCLEUS; CHROMOSOME 17; CHROMOSOME 21; CLINICAL ARTICLE; COLOR; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; CYTOKINESIS; FLUORESCENCE IN SITU HYBRIDIZATION; FOLIC ACID DEFICIENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; VOLUNTEER;

ANEUPLOIDY; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 21; FOLIC ACID; FOLIC ACID DEFICIENCY; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOCYTES; MICRONUCLEUS TESTS; RIBOFLAVIN;

EID: 3042591660     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2004.03.008     Document Type: Article

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