Spectral karyotyping and interphase FISH reveal abnormalities not detected by conventional G-banding. Implications for treatment stratification of childhood acute lymphoblastic leukaemia: Detailed analysis of 70 cases

European Journal of Haematology

Volumn 68, Issue 1, 2002, Pages 31-41

  Nordgren, Ann ^a,b   Heyman, Mats ^b   Sahlén, Sigrid ^a   Schoumans, Jacqueline ^a,b   Söderhäll, Stefan ^b   Nordenskjöld, Magnus ^a,b   Blennow, Elisabeth ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Childhood ALL; Chromosome aberrations; Interphase FISH; SKY

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER CLASSIFICATION; CANCER THERAPY; CHILD; CHILDHOOD CANCER; CHROMOSOME 1Q; CHROMOSOME 21P; CHROMOSOME 6Q; CHROMOSOME 8Q; CHROMOSOME ABERRATION; CHROMOSOME BANDING PATTERN; CHROMOSOME TRANSLOCATION 12; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DELETION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; INFANT; INTERPHASE; KARYOTYPING; MAJOR CLINICAL STUDY; MALE; PLOIDY; PRIORITY JOURNAL; PROGNOSIS;

ADOLESCENT; ANEUPLOIDY; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; CHROMOSOMES, HUMAN; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 8; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA-BINDING PROTEINS; FEMALE; FUSION PROTEINS, BCR-ABL; GENES, ABL; GENES, P16; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; INFANT, NEWBORN; INTERPHASE; KARYOTYPING; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; LEUKEMIA, PRE-B-CELL; LEUKEMIA, T-CELL; MALE; MYELOID-LYMPHOID LEUKEMIA PROTEIN; ONCOGENE PROTEINS, FUSION; PHILADELPHIA CHROMOSOME; PROGNOSIS; PROTO-ONCOGENES; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC;

EID: 0036105582     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0609.2002.00547.x     Document Type: Article

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