Astrocytes down-regulate neuronal β-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner

European Journal of Neuroscience

Volumn 14, Issue 2, 2001, Pages 256-266

  Vincent, Bruno ^a,b   Smith, Jonathan D ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Alzheimer; Apolipoprotein E; Astrocytes; Neurons; Transgenic mice

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; RECOMBINANT PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN CELL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; GENE MUTATION; GENE OVEREXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN POLYMORPHISM; PROTEIN PROCESSING; PROTEIN SECRETION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; ASTROCYTES; CELL COMMUNICATION; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; CULTURE MEDIA, SERUM-FREE; DOWN-REGULATION; HUMANS; MICE; MICE, TRANSGENIC; NEURONS; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; SYNAPSINS; TRANSFECTION;

EID: 0034889517     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01643.x     Document Type: Article

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