cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: Generation of a molecular model

Biochemical Journal

Volumn 333, Issue 1, 1998, Pages 139-149

  Hoffmann, Ralf ^a,c   Wilkinson, Ian R ^a,d   McCallum, J Fraser ^a   Engels, Peter ^b,c   Houslay, Miles D ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b Preclinical Research   (Switzerland)

^c Biofrontera Pharmaceuticals GmbH   (Germany)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP PHOSPHODIESTERASE; GLUTAMIC ACID; MUTANT PROTEIN; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; SERINE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; HUMAN; MOLECULAR MODEL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0032127768     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3330139     Document Type: Article

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