Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells

Biochemical Journal

Volumn 347, Issue 2, 2000, Pages 571-578

  MacKenzie, Simon J ^a   Houslay, Miles D ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Interferon ; Lipopolysaccharide; Phosphoinositide 3 kinase; Protein kinase A; Rapamycin

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYCLIC AMP PHOSPHODIESTERASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHODIESTERASE IV; RAPAMYCIN; ROLIPRAM; WORTMANNIN;

ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MONOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANDROSTADIENES; BLOTTING, WESTERN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INTERFERON TYPE II; ISOENZYMES; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PRECIPITIN TESTS; RIBOSOMAL PROTEIN S6 KINASES; ROLIPRAM; SIROLIMUS; U937 CELLS;

BACTERIA (MICROORGANISMS);

EID: 0034655448     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3470571     Document Type: Article

References (48)

1. 1 Murphy, B. J. and Scott, J. D. (1998) Trends Cardiovasc. Med 8, 89-95
2. 2 Colledge, M. and Scott, J. D. (1999) Trends Cell Biol. 9, 216-221
3. 3 Coghlan, V. M., Bergeson, S.E., Langeberg, L., Nilaver, G. and Scott, J. D. (1993) Mol. Cell. Biochem. 127, 309-319
4. 4 Rubin, C. S. (1994) Biochim. Biophys. Acta 1224, 467-479
5. 5 Houslay, M. D. and Milligan, G. (1997) Trends Biochem. Sci. 22, 217-224
6. 6 Teixeira, M, M., Gristwood, R. W., Cooper, N. and Hellewell, P. G. (1997) Trends Pharmacol. Sci. 18, 164-170
7. 7 Torphy, T. J. (1998) Am. J. Respir. Crit. Care Med. 157, 351-70
8. 8 Dent, G. and Giembycz, M. A. (1995) Clin. Immunother. 3, 423-437
9. 9 Souness, J. E. and Rao, S. (1997) Cell. Signalling 9, 227-236
10. 10 Houslay, M. D., Sullivan, M. and Bolger, G. B. (1998) Adv. Pharmacol. 44, 225-342
11. 11 Sullivan, M., Rena, G., Begg, F , Gordon, L., Olsen, A. S. and Houslay, M. D. (1998) Biochem. J. 333, 693-703
12. 12 Sullivan, M., Olsen, A. S. and Houslay, M. D. (1999) Cell. Signalling 11, 735-742
13. 13 Conti, M. and Jin, S. L. C. (1999) Prog. Nucleic Acid Res. 63, 1-38
14. 14 Schafer, P. H., Wang, L., Wadsworlh, S. A., Davis, J. E. and Siekierka, J. J. (1999) J. Immunol. 162, 659-668
15. 15 Uddin, S., Majchrzak, B., Woodson, J., Arunkumar, P., Alsayed, Y., Pine, R., Young, P. R., Fish, E. N. and Platanias, L. C. (1999) J. Biol. Chem. 274, 30127-30131
16. 16 Han, J., Lee, J. D., Tobias, P. S. and Ulevitch, R. J. (1993) J. Biol. Chem. 268, 25009-25014
17. 17 Huston, E., Pooley, L., Julien, J., Scotland, G., McPhee, I., Sullivan, M., Bolger, G. and Houslay, M. D. (1996) J. Biol. Chem. 271, 31334-31344
18. 18 Huston, E., Lumb, S., Russell, A., Catterall, C., Ross, A. H., Steele, M. R., Bolger, G. B., Perry, M., Owens, R. and Houslay, M. D. (1997) Biochem. J 328, 549-558
19. 19 MacKenzie, S. J., Yarwood, S. J., Peden, A. H., Bolger, G. B., Vernon, R. J. and Houslay, M. D. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 3549-3554
20. 20 Bolger, G. B., Erdogan, S., Jones, R. E., Loughney, K., Scotland, G., Hoffmann, R., Wilkinson, I., Farrell, C. and Houslay, M D. (1997) Biochem. J. 328, 539-548
21. 21 Hoffmann, R., Baillie, G. S., MacKenzie, S. J., Yarwood, S. J. and Houslay, M. D. (1999) EMBO J. 18, 893-903
22. 22 Erdogan, S. and Houslay, M. D. (1997) Biochem. J. 321, 165-175
23. 23 Marchmont, R. J. and Houslay, M. D. (1980) Biochem. J. 187, 381-392
24. 24 Thompson, W. J. and Appleman, M. M. (1971) Biochemistry 10, 311-316
25. 25 Spence, S., Rena, G., Sweeney, G. and Houslay, M. D. (1995) Biochem. J. 310, 975-982
26. 26 Manganiello, V. C., Taira, M., Degerman, E. and Belfrage, P. (1995) Cell. Signalling 7, 445-455
27. 27 Owens, R. J., Lumb, S., Rees-Milton, K., Russell, A., Baldock, D., Lang, V , Crabbe, T., Ballesteros, M. and Perry, M. J. (1997) Cell. Signalling 9, 575-585
28. 28 Torphy, T. J., Zhou, H. L., Foley, J. J., Sarau, H. M., Manning, C. D. and Barnette, M. S. (1995) J. Biol. Chem. 270, 23598-23604
29. 29 Torphy, T. J., Zhou, H. L. and Cieslinski, L. B. (1992) J. Pharmacol. Exp. Ther. 263, 1195-1205
30. 30 Manning, C. D., McLaughlin, M. M., Livi, G. P., Cieslinski, L. B., Torphy, T. J. and Barnette, M. S. (1996) Mol. Pharmacol. 276, 810-818
31. 31 Verghese, M. W., McConnell, R. T., Lenhard, J. M., Hamacher, L. and Jin, S.-L. C. (1995) Mol. Pharmacol 47, 1164-1171
32. 32 Montminy, M. (1997) Annu. Rev. Biochem. 66, 807-822
33. 33 Cuenda, A., Rouse, J., Doza, Y. N., Meier, R., Cohen, P., Gallagher, T. F., Young, P. R. and Lee, J. C. (1995) FEBS Lett. 364, 229-233
34. 34 Nick, J. A., Avdi, N. J., Young, S. K., Lehman, L. A., McDonald, P. P., Frasch, S. C., Billstrom, M. A., Henson, P. M., Johnson, G. L. and Worthen, G. S. (1999) J. Clin. Invest. 103, 851-858
35. 35 Manthey, C. L., Wang, S. W., Kinney, S.D and Yao, Z. (1998) J. Leukocyte Biol 64, 409-417
36. 36 Seldon, P. M., Barnes, P. J., Meja, K. and Giembycz, M. A. (1995) Mol. Pharmacol. 48, 747-757
37. 37 Souness, J. E., Griffin, M., Maslen, C., Ebsworth, K., Scott, L. C., Pollock, K., Palfreyman, M. N. and Karlsson, J. A. (1996) Br. J. Pharmacol. 118, 649-658
38. 38 Schudt, C., Tenor, H. and Hatzelmann, A. (1995) Eur. Respir. J. 8, 1179-1183
39. 39 Nakanishi, S., Yano, H and Matsuda, Y. (1995) Cell. Signalling 7, 545-557
40. 40 Brown, E. J. and Schreiber, S. L. (1996) Cell 86, 517-520
41. 41 Herrera-Velit, P. R. N. E. (1996) J. Immunol. 156, 1157-1165
42. 42 Herrera-Velit, P., Knutson, K. L. and Reiner, N. E. (1997) J. Biol. Chem. 272, 16445-16452
43. 43 Bolger, G. (1994) Cell. Signalling 6, 851-859
44. 44 Kovala, T., Sanwal, B. D. and Ball, E. H. (1997) Biochemistry 36, 2968-2976
45. 45 McPhee, I., Yarwood, S. J., Huston, E., Scotland, G., Beard, M. B., Ross, A. H., Houslay, E. S. and Houslay, M. D. (1999) J. Biol. Chem. 274, 11796-11810
46. 46 Abraham, R. T. and Wiederrecht, G. J. (1996) Annu. Rev. Immunol. 14, 483-510
47. 47 Scott, P. H. and Lawrence, Jr., J. C. (1998) J. Biol. Chem 273, 34496-34501
48. 48 Ma, D., Wu, P., Egan, R. W., Billah, M. M. and Wang, P. (1999) Mol. Pharmacol. 55, 50-57