Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 20, 1998, Pages 11921-11926

  Wang, May Yun ^b,c   Koyama, Kazunori ^b,c   Shimabukuro, Michio ^b,c   Mangelsdorf, David ^a,b   Newgard, Christopher B ^a,b   Unger, Roger H ^a,b,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALITRETINOIN; ARGININE; CLOFIBRATE; GLUCOKINASE; GLUCOSE TRANSPORTER; HEXOKINASE; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PREPROINSULIN; RETINOID X RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; DIMERIZATION; GENE OVEREXPRESSION; GLUCOSE TRANSPORT SYSTEM; INSULIN RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR GENE; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CLOFIBRATE; DIABETES MELLITUS, TYPE 2; DNA PRIMERS; DNA-BINDING PROTEINS; GENE EXPRESSION; GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; INSULIN; ISLETS OF LANGERHANS; KINETICS; MALE; MICROBODIES; MONOSACCHARIDE TRANSPORT PROTEINS; MUTATION; OBESITY; POLYMERASE CHAIN REACTION; RATS; RATS, ZUCKER; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0032578484     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.20.11921     Document Type: Article

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