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Volumn 14, Issue 12, 2005, Pages 1475-1486

Targeting integrins for the control of tumour angiogenesis

Author keywords

Angiogenesis; Extracellular matrix; Integrin antagonists; Matrix immobilised cryptic ECM epitopes

Indexed keywords

ALPHA4 BETA7 ANTIGEN ANTAGONIST; ANASTELLIN; ANGIOGENESIS INHIBITOR; ANTISENSE OLIGONUCLEOTIDE; BLOCKING AGENT; CANSTATIN; DISINTEGRIN; ENDOREPELIN; ENDOSTATIN; FASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTEGRIN; INTEGRIN ANTAGONIST; INTEGRIN ANTIBODY; LIGAND; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY LM 609; MONOCLONAL ANTIBODY M200; OBTUSTATIN; PEPTIDE; PROTEIN ANTIBODY; RESTIN; RETINA S ANTIGEN; SEMAPHORIN; SULFONAMIDE; THROMBOSPONDIN 1; TUMSTATIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERY LATE ACTIVATION ANTIGEN 4 ANTAGONIST; VERY LATE ACTIVATION ANTIGEN 5 ANTAGONIST;

EID: 28644439936     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.14.12.1475     Document Type: Review
Times cited : (31)

References (101)
  • 1
    • 0036831559 scopus 로고    scopus 로고
    • Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy
    • RAFII S, LYDEN D, BENEZRA R, HATTORI K, HEISSIG B: Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy. Nat. Rev. Caner. (2002) 2(11):826-835.
    • (2002) Nat. Rev. Caner. , vol.2 , Issue.11 , pp. 826-835
    • Rafii, S.1    Lyden, D.2    Benezra, R.3    Hattori, K.4    Heissig, B.5
  • 3
    • 0141705426 scopus 로고    scopus 로고
    • Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry
    • RUF W, SEFTOR EA, PETROVAN RJ et al.: Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry. Cancer Res. (2003) 63(17):5381-5389.
    • (2003) Cancer Res. , vol.63 , Issue.17 , pp. 5381-5389
    • Ruf, W.1    Seftor, E.A.2    Petrovan, R.J.3
  • 4
    • 6944230090 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on vascular network formation by human endothelial and melanoma cells
    • VAN DER SCHAFT DW, SEFTOR RE, SEFTOR EA et al.: Effects of angiogenesis inhibitors on vascular network formation by human endothelial and melanoma cells. J. Natl. Cancer Inst. (2004) 96(19):1473-1477.
    • (2004) J. Natl. Cancer Inst. , vol.96 , Issue.19 , pp. 1473-1477
    • Van Der Schaft, D.W.1    Seftor, R.E.2    Seftor, E.A.3
  • 6
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • RISAU W: Mechanisms of angiogenesis. Nature (1997) 386(6626):671-674.
    • (1997) Nature , vol.386 , Issue.6626 , pp. 671-674
    • Risau, W.1
  • 7
    • 0037067431 scopus 로고    scopus 로고
    • Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity
    • WIJELATH ES, MURRAY J, RAHMAN S et al.: Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity. Cir. Res. (2002) 19(1):25-31.
    • (2002) Cir. Res. , vol.19 , Issue.1 , pp. 25-31
    • Wijelath, E.S.1    Murray, J.2    Rahman, S.3
  • 8
    • 22344437713 scopus 로고    scopus 로고
    • Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
    • LEE S, JILANI SM, NIKOLOVA GV, CARPIZO D, IRUELA-ARISPE M: Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J. Cell Biol. (2005) 169(4):681-691.
    • (2005) J. Cell Biol. , vol.169 , Issue.4 , pp. 681-691
    • Lee, S.1    Jilani, S.M.2    Nikolova, G.V.3    Carpizo, D.4    Iruela-Arispe, M.5
  • 10
    • 0033709053 scopus 로고    scopus 로고
    • Generation of monoclonal antibodies to cryptic collagen sites by using subtractive immunization
    • XU J, RODRIGUEZ D, KIM JJ, BROOKS PC: Generation of monoclonal antibodies to cryptic collagen sites by using subtractive immunization. Hybridoma. (2000) 19(5):375-385.
    • (2000) Hybridoma , vol.19 , Issue.5 , pp. 375-385
    • Xu, J.1    Rodriguez, D.2    Kim, J.J.3    Brooks, P.C.4
  • 11
    • 0035802109 scopus 로고    scopus 로고
    • Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo
    • XU J, RODRIGUEZ D, PETITCLERC E et al.: Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo. J. Cell Biol. (2001) 154(5):1069-1079.
    • (2001) J. Cell Biol. , vol.154 , Issue.5 , pp. 1069-1079
    • Xu, J.1    Rodriguez, D.2    Petitclerc, E.3
  • 12
    • 0036791588 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9-dependent exposure of a cryptic migratory control site in collagen is required before retinal angiogenesis
    • HANGAI M, KITAYA N, XU J et al.: Matrix metalloproteinase-9-dependent exposure of a cryptic migratory control site in collagen is required before retinal angiogenesis. Am. J. Pathol. (2002) 161(4):1429-1437.
    • (2002) Am. J. Pathol. , vol.161 , Issue.4 , pp. 1429-1437
    • Hangai, M.1    Kitaya, N.2    Xu, J.3
  • 14
    • 15944418189 scopus 로고    scopus 로고
    • CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells
    • WANG T, WARD Y, TIAN L et al.: CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells. Blood (2005) 105(7):2836-2844.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2836-2844
    • Wang, T.1    Ward, Y.2    Tian, L.3
  • 15
    • 16644381982 scopus 로고    scopus 로고
    • Role of pericytes in vascular morphogenesis
    • BETSHOLTZ C, LINDBLOM P, GERHARDT H: Role of pericytes in vascular morphogenesis. EXS. (2005) 94:115-125.
    • (2005) EXS. , vol.94 , pp. 115-125
    • Betsholtz, C.1    Lindblom, P.2    Gerhardt, H.3
  • 16
    • 0030584077 scopus 로고    scopus 로고
    • The adaptor protein Shc couples a class of integrins to the control the cell cycle progression
    • WARY KK, MAINIERO F, ISAKOFF SJ, MARCANTIO EE, GIANCOTTI FG: The adaptor protein Shc couples a class of integrins to the control the cell cycle progression. Cell (1996) 87(4):733-743.
    • (1996) Cell , vol.87 , Issue.4 , pp. 733-743
    • Wary, K.K.1    Mainiero, F.2    Isakoff, S.J.3    Marcantio, E.E.4    Giancotti, F.G.5
  • 18
    • 0010712792 scopus 로고    scopus 로고
    • Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity
    • BROOKS PC, SILLETTI S, VON SCHALSHA TL, FRIEDLANDER M, CHERESH DA: Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell (1998) 92(3):391-400.
    • (1998) Cell , vol.92 , Issue.3 , pp. 391-400
    • Brooks, P.C.1    Silletti, S.2    Von Schalsha, T.L.3    Friedlander, M.4    Cheresh, D.A.5
  • 19
    • 24044459285 scopus 로고    scopus 로고
    • Matrix metalloproteinases and angiogenesis
    • RUNDHAUG JE: Matrix metalloproteinases and angiogenesis. J. Cell. Mol. Med. (2005) 9(2):267-285.
    • (2005) J. Cell. Mol. Med. , vol.9 , Issue.2 , pp. 267-285
    • Rundhaug, J.E.1
  • 22
    • 13444274458 scopus 로고    scopus 로고
    • 1 integrin conformation and function by urokinase receptor binding
    • 1 integrin conformation and function by urokinase receptor binding. J. Cell Biol. (2005) 168(3):501-511.
    • (2005) J. Cell Biol. , vol.168 , Issue.3 , pp. 501-511
    • Wei, Y.1    Czekay, R.P.2    Robillard, L.3
  • 23
    • 0036829020 scopus 로고    scopus 로고
    • Molecular basis of endothelial cell morphogenesis in three-dimensional extracellular matrices
    • DAVIS GE, BAYLESS KJ, MAVILA A: Molecular basis of endothelial cell morphogenesis in three-dimensional extracellular matrices. Anat. Rec. (2002) 268(3):252-275.
    • (2002) Anat. Rec. , vol.268 , Issue.3 , pp. 252-275
    • Davis, G.E.1    Bayless, K.J.2    Mavila, A.3
  • 24
    • 0030056112 scopus 로고    scopus 로고
    • Cell adhesion molecules in angiogenesis
    • BROOKS PC: Cell adhesion molecules in angiogenesis. Cancer Met. Rev. (1996) 15(2):187-194.
    • (1996) Cancer Met. Rev. , vol.15 , Issue.2 , pp. 187-194
    • Brooks, P.C.1
  • 25
    • 9644289575 scopus 로고    scopus 로고
    • Integrins: Versatile integrators of extracellular signals
    • FFRENCH-CONSTANT C, COLOGNATO H: Integrins: versatile integrators of extracellular signals. Trend Cell. Biol. (2004) 14(12):678-686.
    • (2004) Trend Cell. Biol. , vol.14 , Issue.12 , pp. 678-686
    • Ffrench-Constant, C.1    Colognato, H.2
  • 26
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • HYNES RO: Integrins: bidirectional, allosteric signaling machines. Cell (2002) 110(6):673-687.
    • (2002) Cell , vol.110 , Issue.6 , pp. 673-687
    • Hynes, R.O.1
  • 27
    • 0036696097 scopus 로고    scopus 로고
    • Integrin structure: New twists and turns in dynamic cell adhesion
    • ARNAOUT MA: Integrin structure: new twists and turns in dynamic cell adhesion. Immunol. Rev. (2002) 186:125-140.
    • (2002) Immunol. Rev. , vol.186 , pp. 125-140
    • Arnaout, M.A.1
  • 29
    • 0142026204 scopus 로고    scopus 로고
    • Therapeutic antagonists and conformational regulation of integrin function
    • SHIMAOKA M, SPRINGER TA: Therapeutic antagonists and conformational regulation of integrin function. Nat. Rev. Drug Dis. (2003) 2(9):703-716.
    • (2003) Nat. Rev. Drug Dis. , vol.2 , Issue.9 , pp. 703-716
    • Shimaoka, M.1    Springer, T.A.2
  • 33
    • 8744300054 scopus 로고    scopus 로고
    • Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion
    • CRITCHLEY DR: Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion. Biochem. Soc. Trans. (2004) 32(Part 5):831-836.
    • (2004) Biochem. Soc. Trans. , vol.32 , Issue.PART 5 , pp. 831-836
    • Critchley, D.R.1
  • 34
    • 0034677760 scopus 로고    scopus 로고
    • New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo
    • PETITCLERC E, BOUTAUD A, PRESTAYKO A et al.: New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo. J. Biol. Chem. (2000) 275(11):8051-8061.
    • (2000) J. Biol. Chem. , vol.275 , Issue.11 , pp. 8051-8061
    • Petitclerc, E.1    Boutaud, A.2    Prestayko, A.3
  • 35
    • 0037805549 scopus 로고    scopus 로고
    • Basement membranes structure, assembly and role in tumor angiogenesis
    • KALLLURY R: Basement membranes: structure, assembly and role in tumor angiogenesis. Nat. Rev. Cancer. (2003) 3(6):422-433.
    • (2003) Nat. Rev. Cancer. , vol.3 , Issue.6 , pp. 422-433
    • Kalllury, R.1
  • 36
    • 20144379162 scopus 로고    scopus 로고
    • Endogenous inhibitors of angiogenesis
    • NYBERG P, XIE L, KALLURI R: Endogenous inhibitors of angiogenesis. Cancer Res. (2005) 65(10):3967-3979.
    • (2005) Cancer Res. , vol.65 , Issue.10 , pp. 3967-3979
    • Nyberg, P.1    Xie, L.2    Kalluri, R.3
  • 37
    • 11844301388 scopus 로고    scopus 로고
    • Matrix revolutions: 'Tails' of basement-membrane components with angiostatic functions
    • BIX G, IOZZO RV: Matrix revolutions: 'tails' of basement-membrane components with angiostatic functions. Trends Cell Biol. (2005) 15(1):52-60.
    • (2005) Trends Cell Biol. , vol.15 , Issue.1 , pp. 52-60
    • Bix, G.1    Iozzo, R.V.2
  • 38
    • 0141509866 scopus 로고    scopus 로고
    • Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis
    • SAGE EH, REED M, FUNK SE et al.: Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis. J. Biol. Chem. (2003) 278(39):849-857.
    • (2003) J. Biol. Chem. , vol.278 , Issue.39 , pp. 849-857
    • Sage, E.H.1    Reed, M.2    Funk, S.E.3
  • 39
    • 85047694396 scopus 로고    scopus 로고
    • Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1
    • ZHONG J, ELICEIRI B, STUPACK D et al.: Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1. J. Clin. Invest. (2003) 112(1):30-41.
    • (2003) J. Clin. Invest. , vol.112 , Issue.1 , pp. 30-41
    • Zhong, J.1    Eliceiri, B.2    Stupack, D.3
  • 42
    • 0041530325 scopus 로고    scopus 로고
    • Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
    • SERINI G, VALDEMBRI D, ZANIVAN S et al.: Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature (2003) 424(6947):391-397.
    • (2003) Nature , vol.424 , Issue.6947 , pp. 391-397
    • Serini, G.1    Valdembri, D.2    Zanivan, S.3
  • 43
    • 0035448316 scopus 로고    scopus 로고
    • Pilot study of vitaxin-an angiogenesis inhibitor-in patients with advanced leiomyosarcomas
    • PATEL SR, JENKINS J, PAPADOPOLOUS N et al.: Pilot study of vitaxin-an angiogenesis inhibitor-in patients with advanced leiomyosarcomas. Cancer (2001) 92(5):1347-1348.
    • (2001) Cancer , vol.92 , Issue.5 , pp. 1347-1348
    • Patel, S.R.1    Jenkins, J.2    Papadopolous, N.3
  • 44
    • 2442488748 scopus 로고    scopus 로고
    • CNTO 95, a fully human monoclonal antibody that inhibits αv integrins, has antitumor and antiangiogenic activity in vivo
    • TRIKHA M, ZHOU Z, NEMETH JA et al.: CNTO 95, a fully human monoclonal antibody that inhibits αv integrins, has antitumor and antiangiogenic activity in vivo. Int. J. Cancer. (2004) 110(3):326-335.
    • (2004) Int. J. Cancer. , vol.110 , Issue.3 , pp. 326-335
    • Trikha, M.1    Zhou, Z.2    Nemeth, J.A.3
  • 45
    • 28644432088 scopus 로고    scopus 로고
    • 1 antibody promotes cell death in proliferating endothelial cells
    • American Association for Cancer Research, Phoenix, USA
    • 1 antibody promotes cell death in proliferating endothelial cells. American Association for Cancer Research, Phoenix, USA (2003).
    • (2003)
    • Bhaskar, V.1    Law, D.A.2    Liu, G.3
  • 46
    • 8744236153 scopus 로고    scopus 로고
    • 7 integrin antagonist after oral administration at single and multiple once-daily ascending doses in healthy volunteers
    • 7 integrin antagonist after oral administration at single and multiple once-daily ascending doses in healthy volunteers. J. Clin. Pharmacol. (2004) 44(12):1368-1378.
    • (2004) J. Clin. Pharmacol. , vol.44 , Issue.12 , pp. 1368-1378
    • Hijazi, Y.1    Welker, H.2    Dorr, A.E.3
  • 48
    • 0034715896 scopus 로고    scopus 로고
    • Insight into extracellular matrix functions from mutant mouse models
    • GUSTAFASSON E, FASSLER R: Insight into extracellular matrix functions from mutant mouse models. Exp. Cell Res. (2000) 261:52-68.
    • (2000) Exp. Cell Res. , vol.261 , pp. 52-68
    • Gustafasson, E.1    Fassler, R.2
  • 55
    • 0031950693 scopus 로고    scopus 로고
    • Urokinase receptor antagonists: Novel agents for the treatment of cancer
    • WEIDLE UH, KONIG B: Urokinase receptor antagonists: novel agents for the treatment of cancer. Expert. Opin. Investig. Drugs. (1998) 7(3):391-403.
    • (1998) Expert. Opin. Investig. Drugs. , vol.7 , Issue.3 , pp. 391-403
    • Weidle, U.H.1    Konig, B.2
  • 56
    • 0042197340 scopus 로고    scopus 로고
    • TIMP-2 mediated inhibition of angiogenesis: An MMP-independent mechanism
    • SEO DW, LI H, GUEDEZ L et al.: TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. Cell. (2003) 114(2):171-180.
    • (2003) Cell. , vol.114 , Issue.2 , pp. 171-180
    • Seo, D.W.1    Li, H.2    Guedez, L.3
  • 57
    • 0035394235 scopus 로고    scopus 로고
    • 5-integrin-negative teratocarcinomas and embryoid bodies
    • 5-integrin-negative teratocarcinomas and embryoid bodies. Cancer Res. (2001) 61(13):5255-5261.
    • (2001) Cancer Res. , vol.61 , Issue.13 , pp. 5255-5261
    • Taverna, D.1    Hynes, R.O.2
  • 58
    • 0028955748 scopus 로고
    • 4 integrins are essential in placental and cardiac development
    • 4 integrins are essential in placental and cardiac development. Development (1995) 121(2):549-560.
    • (1995) Development , vol.121 , Issue.2 , pp. 549-560
    • Yang, J.T.1    Rayburn, H.2    Hynes, R.O.3
  • 59
    • 1542313880 scopus 로고    scopus 로고
    • 1 integrin mediates selective endothelial cell responses to thrombospondins 1 and 2 in vitro and modulates angiogenesis in vivo
    • 1 integrin mediates selective endothelial cell responses to thrombospondins 1 and 2 in vitro and modulates angiogenesis in vivo. Circ. Res. (2004) 94(4):462-470.
    • (2004) Circ. Res. , vol.94 , Issue.4 , pp. 462-470
    • Calzada, M.J.1    Zhou, L.2    Sipes, J.M.3
  • 62
    • 26444557730 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase IV
    • 2+/calmodulin-dependent protein kinase IV. J. Cell Biochem. (2005) 95(6):1214-1223.
    • (2005) J. Cell Biochem. , vol.95 , Issue.6 , pp. 1214-1223
    • Lee, B.H.1    Ruoslahti, E.2
  • 64
    • 0346365369 scopus 로고    scopus 로고
    • Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells
    • SCHUCH G, HEYMACH JV, NOMI M et al.: Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells. Cancer Res. (2003) 63(23):8345-8350.
    • (2003) Cancer Res. , vol.63 , Issue.23 , pp. 8345-8350
    • Schuch, G.1    Heymach, J.V.2    Nomi, M.3
  • 65
    • 0036324664 scopus 로고    scopus 로고
    • Endostatin is a potential inhibitor of Wnt signaling
    • HANAI J, GLOY J, KARUMANCHI SA et al.: Endostatin is a potential inhibitor of Wnt signaling. J. Cell Biol. (2002) 158(3):529-539.
    • (2002) J. Cell Biol. , vol.158 , Issue.3 , pp. 529-539
    • Hanai, J.1    Gloy, J.2    Karumanchi, S.A.3
  • 67
    • 0030639225 scopus 로고    scopus 로고
    • Regulation of capillary formation by laminin and other components of the extracellular matrix
    • GRANT DS, KLEINMAN HK: Regulation of capillary formation by laminin and other components of the extracellular matrix. EXS (1997) 79:317-333.
    • (1997) EXS , vol.79 , pp. 317-333
    • Grant, D.S.1    Kleinman, H.K.2
  • 71
    • 0029000246 scopus 로고
    • The involvement of thrombin RGD in metastasis: Characterization of a cryptic adhesive site
    • BAR-SHAVIT R, GINZBURG Y, MAOZ M, VLODAVSKY I, PERETZ T: The involvement of thrombin RGD in metastasis: characterization of a cryptic adhesive site. Isr. J. Med. Sci. (1995) 31(2-3) 86-94.
    • (1995) Isr. J. Med. Sci. , vol.31 , Issue.2-3 , pp. 86-94
    • Bar-Shavit, R.1    Ginzburg, Y.2    Maoz, M.3    Vlodavsky, I.4    Peretz, T.5
  • 72
    • 0033824172 scopus 로고    scopus 로고
    • Urokinase receptor and integrin partnership: Coordination of signaling for cell adhesion, migration and growth
    • OSSOWSKI L, AGUIRRE-GHISO JA: Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth. Curr. Opin. Cell Biol. (2000) 12(5): 613-620.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , Issue.5 , pp. 613-620
    • Ossowski, L.1    Aguirre-Ghiso, J.A.2
  • 73
    • 14244262503 scopus 로고    scopus 로고
    • 3-integrin and activating VEGF-R2
    • 3-integrin and activating VEGF-R2. Microvasc. Res. (2004) 68(3):169-178.
    • (2004) Microvasc. Res. , vol.68 , Issue.3 , pp. 169-178
    • Hall, H.1    Hubbell, J.A.2
  • 75
    • 11244352382 scopus 로고    scopus 로고
    • 3 integrin linked signaling pathways: Cellular responses to changes in multiple signaling inputs
    • 3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs. Mol. Endocrinol. (2005) 19(1):1-11.
    • (2005) Mol. Endocrinol. , vol.19 , Issue.1 , pp. 1-11
    • Clemmons, D.R.1    Maile, L.A.2
  • 76
    • 0034817142 scopus 로고    scopus 로고
    • Identification of a candidate integrin-fraction associated with the activated form of the PDGF-receptor
    • SCHNELLER M: Identification of a candidate integrin-fraction associated with the activated form of the PDGF-receptor. Biochem. Biophys. Res. Commun. (2001) 281(2):595-602.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , Issue.2 , pp. 595-602
    • Schneller, M.1
  • 77
    • 0037840309 scopus 로고    scopus 로고
    • Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61)
    • BRIGSTOCK DR: Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61). Angiogenesis (2002) 5(3):153-165.
    • (2002) Angiogenesis , vol.5 , Issue.3 , pp. 153-165
    • Brigstock, D.R.1
  • 78
    • 22144494707 scopus 로고    scopus 로고
    • 3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis
    • 3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis. Endocrinology (2005) 146(7):2864-2871.
    • (2005) Endocrinology , vol.146 , Issue.7 , pp. 2864-2871
    • Bergh, J.J.1    Lin, H.Y.2    Lansing, L.3
  • 79
    • 0035895247 scopus 로고    scopus 로고
    • A fibronectin fragment inhibits tumor growth, angiogenesis and metastasis
    • YI M, RUOSLAHTI E: A fibronectin fragment inhibits tumor growth, angiogenesis and metastasis. Proc. Natl. Acad. Sci. USA (2001) 98(2):620-624.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.2 , pp. 620-624
    • Yi, M.1    Ruoslahti, E.2
  • 85
    • 0038724937 scopus 로고    scopus 로고
    • Role of Raf in vascular protection from distinct apoptotic stimuli
    • ALAVI A, HOOD JD, FRAUSTO R, STUPACK DG, CHERESH DA: Role of Raf in vascular protection from distinct apoptotic stimuli. Science (2003) 301(5629):94-96.
    • (2003) Science , vol.301 , Issue.5629 , pp. 94-96
    • Alavi, A.1    Hood, J.D.2    Frausto, R.3    Stupack, D.G.4    Cheresh, D.A.5
  • 87
    • 0028670833 scopus 로고
    • 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell (1994) 79(7):1157-1164.
    • (1994) Cell , vol.79 , Issue.7 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3
  • 89
    • 0344731256 scopus 로고    scopus 로고
    • 3 promotes M21 melanoma growth in human skin by regulating tumor cell survival
    • 3 promotes M21 melanoma growth in human skin by regulating tumor cell survival. Cancer Res. (1999) 59(11):2724-2730.
    • (1999) Cancer Res. , vol.59 , Issue.11 , pp. 2724-2730
    • Petitcler, E.1    Stromblad, S.2    Von Schalscha, T.I.3
  • 91
  • 94
    • 0038466189 scopus 로고    scopus 로고
    • Localization of integrin α(v)β3 and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in cutaneous and oral melanomas of dog
    • RAWLINGS NG, SIMKO E, BEBCHUK T, CALDWELL SJ, SINGH B: Localization of integrin α(v)β3 and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in cutaneous and oral melanomas of dog. Histol. Histopathol. (2003) 18(3):819-826.
    • (2003) Histol. Histopathol. , vol.18 , Issue.3 , pp. 819-826
    • Rawlings, N.G.1    Simko, E.2    Bebchuk, T.3    Caldwell, S.J.4    Singh, B.5
  • 95
    • 0042704757 scopus 로고    scopus 로고
    • Extracellular matrix-bound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation
    • HUTCHINGS H, ORTEGA N, PLOUET J: Extracellular matrix-bound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation. FASEB (2003) 17(11):1520-1522.
    • (2003) FASEB , vol.17 , Issue.11 , pp. 1520-1522
    • Hutchings, H.1    Ortega, N.2    Plouet, J.3
  • 97
    • 0037189380 scopus 로고    scopus 로고
    • Tumor regression by targeted gene delivery to the neovasculature
    • HOOD JD, BEDNARSKI M, FRAUSTO R et al.: Tumor regression by targeted gene delivery to the neovasculature. Science (2002) 296(5577):2404-2407.
    • (2002) Science , vol.296 , Issue.5577 , pp. 2404-2407
    • Hood, J.D.1    Bednarski, M.2    Frausto, R.3
  • 98
    • 13944278751 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugated as a model for integrin-targeted drug delivery
    • CHEN X, PLASENCIA C, HOU Y, NEAMATI N: Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugated as a model for integrin-targeted drug delivery, J. Med. Chem. (2005) 48(4):1098-1106.
    • (2005) J. Med. Chem. , vol.48 , Issue.4 , pp. 1098-1106
    • Chen, X.1    Plasencia, C.2    Hou, Y.3    Neamati, N.4
  • 100
    • 20144386005 scopus 로고    scopus 로고
    • Overexpression of laminin-5 γ-2 chain and its prognostic significance in urothelial carcinoma of urinary bladder: Association with expression of cyclooxygenase 2, epidermal growth factor, and human epidermal growth factor 2
    • KIYOSHIMA K, ODA Y, KINUKAWA N, NAITO S, TSUNEYOSHI M: Overexpression of laminin-5 γ-2 chain and its prognostic significance in urothelial carcinoma of urinary bladder: association with expression of cyclooxygenase 2, epidermal growth factor, and human epidermal growth factor 2. Hum. Pathol. (2005) 36(5):522-530.
    • (2005) Hum. Pathol. , vol.36 , Issue.5 , pp. 522-530
    • Kiyoshima, K.1    Oda, Y.2    Kinukawa, N.3    Naito, S.4    Tsuneyoshi, M.5
  • 101
    • 2342427004 scopus 로고    scopus 로고
    • Diagnostic and therapeutic applications of recombinant antibodies: Targeting the extra-domain B of fibronectin, a marker of tumor angiogenesis
    • EBBINGHAUS C, SCHEUERMANN J, NERI D, ELIA G: Diagnostic and therapeutic applications of recombinant antibodies: targeting the extra-domain B of fibronectin, a marker of tumor angiogenesis. Curr. Pharm. Des. (2004) 10(13):1537-1549.
    • (2004) Curr. Pharm. Des. , vol.10 , Issue.13 , pp. 1537-1549
    • Ebbinghaus, C.1    Scheuermann, J.2    Neri, D.3    Elia, G.4


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