메뉴 건너뛰기




Volumn 95, Issue 6, 2005, Pages 1214-1223

α5β1 integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca2+/ calmodulin-dependent protein kinase IV

Author keywords

Akt; Bcl 2; CaMK; Cell adhesion; Fibronectin; Integrin

Indexed keywords

ALPHAV BETA1 INTEGRIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FIBRONECTIN RECEPTOR; FOCAL ADHESION KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE B; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; CALMODULIN DEPENDENT PROTEIN KINASE IV; CALMODULIN-DEPENDENT PROTEIN KINASE IV;

EID: 26444557730     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20488     Document Type: Article
Times cited : (64)

References (46)
  • 3
    • 0032562080 scopus 로고    scopus 로고
    • Fibronectin binding promotes a PKC-dependent modulation of NF-κB in human T cells
    • Bearz A, Colombatti TA, Formisano S, Pucillo C. 1998. Fibronectin binding promotes a PKC-dependent modulation of NF-κB in human T cells. Biochem Biophy Res Commun 243:732-737.
    • (1998) Biochem Biophy Res Commun , vol.243 , pp. 732-737
    • Bearz, A.1    Colombatti, T.A.2    Formisano, S.3    Pucillo, C.4
  • 4
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • Brooks PC, Clark RA, Cheresh DA. 1994a. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 264:569-571.
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 5
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA. 1994b. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79:1157-1164.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3    Reisfeld, R.A.4    Hu, T.5    Klier, G.6    Cheresh, D.A.7
  • 7
    • 0028877919 scopus 로고
    • Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for Src family kinases
    • Calalb MB, Polte TR, Hanks SK. 1995. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for Src family kinases. Mol Cell Biol 15:954-963.
    • (1995) Mol Cell Biol , vol.15 , pp. 954-963
    • Calalb, M.B.1    Polte, T.R.2    Hanks, S.K.3
  • 8
    • 0027970468 scopus 로고
    • Stimulation of phosphatidylinositol 3′-kinase association with focal adhesion kinase by platelet-derived growth factor
    • Chen HC, Guan JL. 1994. Stimulation of phosphatidylinositol 3′-kinase association with focal adhesion kinase by platelet-derived growth factor. J Biol Chem 269:31229-31233.
    • (1994) J Biol Chem , vol.269 , pp. 31229-31233
    • Chen, H.C.1    Guan, J.L.2
  • 9
    • 0035793596 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase cascades in transcriptional regulation
    • 2+/calmodulin-dependent protein kinase cascades in transcriptional regulation. J Biol Chem 276:2975-2978.
    • (2001) J Biol Chem , vol.276 , pp. 2975-2978
    • Corcoran, E.E.1    Means, A.R.2
  • 10
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME. 1999. Cellular survival: A play in three Akts. Genes Dev 13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 11
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Francis H. 1994. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124:619-626.
    • (1994) J Cell Biol , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 13
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion-dependent cell survival by focal adhesion kinase
    • Frisch SM, Vuori K, Ruoslahti E, Chan-Hui PY. 1996. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 134:793-799.
    • (1996) J Cell Biol , vol.134 , pp. 793-799
    • Frisch, S.M.1    Vuori, K.2    Ruoslahti, E.3    Chan-Hui, P.Y.4
  • 14
    • 0033794569 scopus 로고    scopus 로고
    • Complexity and specificity of integrin signaling
    • Giancotti FG. 2000. Complexity and specificity of integrin signaling. Nat Cell Biol 2:E13-E14.
    • (2000) Nat Cell Biol , vol.2
    • Giancotti, F.G.1
  • 16
    • 0037198274 scopus 로고    scopus 로고
    • NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells
    • Heckman CA, Mehew JW, Boxer LM. 2002. NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells. Oncogene 21:3898-3908.
    • (2002) Oncogene , vol.21 , pp. 3898-3908
    • Heckman, C.A.1    Mehew, J.W.2    Boxer, L.M.3
  • 18
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes RO. 2002. Integrins: Bidirectional, allosteric signaling machines. Cell 110:673-687.
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 19
    • 0032547796 scopus 로고    scopus 로고
    • Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
    • Ilic D, Almeida EA, Schlaepfer DD, Dazin P, Aizawa S, Damsky CH. 1998. Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. J Cell Biol 143:547-560.
    • (1998) J Cell Biol , vol.143 , pp. 547-560
    • Ilic, D.1    Almeida, E.A.2    Schlaepfer, D.D.3    Dazin, P.4    Aizawa, S.5    Damsky, C.H.6
  • 20
    • 0038642118 scopus 로고    scopus 로고
    • Cell spreading controls endoplasmic and nuclear calcium: A physical gene regulation pathway from the cell surface to the nucleus
    • Itano N, Okamoto S, Zhang D, Lipton SA, Ruoslahti E. 2003. Cell spreading controls endoplasmic and nuclear calcium: A physical gene regulation pathway from the cell surface to the nucleus. Proc Natl Acad Sci USA 100:5181-5186.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5181-5186
    • Itano, N.1    Okamoto, S.2    Zhang, D.3    Lipton, S.A.4    Ruoslahti, E.5
  • 21
    • 0035827584 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase IV stimulates nuclear factor-kappa B transactivation via phosphorylation of the p65 subunit
    • 2+/calmodulin-dependent protein kinase IV stimulates nuclear factor-kappa B transactivation via phosphorylation of the p65 subunit. J Biol Chem 276:20005-20010.
    • (2001) J Biol Chem , vol.276 , pp. 20005-20010
    • Jang, M.K.1    Goo, Y.H.2    Sohn, Y.C.3    Kim, Y.S.4    Lee, S.K.5    Kang, H.6    Cheong, J.7    Lee, J.W.8
  • 22
    • 0030913673 scopus 로고    scopus 로고
    • Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
    • Khwaja A, Rodriguez-Viciana P, Wennstrom S, Warne PH, Downward J. 1997. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J 16:2783-2793.
    • (1997) EMBO J , vol.16 , pp. 2783-2793
    • Khwaja, A.1    Rodriguez-Viciana, P.2    Wennstrom, S.3    Warne, P.H.4    Downward, J.5
  • 23
    • 0030839766 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation
    • King WG, Mattaliano MD, Chan TO, Tsichlis PN, Brugge JS. 1997. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Mol Cell Biol 17:4406-4418.
    • (1997) Mol Cell Biol , vol.17 , pp. 4406-4418
    • King, W.G.1    Mattaliano, M.D.2    Chan, T.O.3    Tsichlis, P.N.4    Brugge, J.S.5
  • 24
  • 25
    • 0028195006 scopus 로고
    • Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells
    • Koopman G, Keehnen RM, Lindhout E, Newman W, Shimizu Y, van Seventer GA, de Groot C, Pals ST. 1994. Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells. J Immunol 152:3760-3767.
    • (1994) J Immunol , vol.152 , pp. 3760-3767
    • Koopman, G.1    Keehnen, R.M.2    Lindhout, E.3    Newman, W.4    Shimizu, Y.5    Van Seventer, G.A.6    De Groot, C.7    Pals, S.T.8
  • 27
    • 0034201965 scopus 로고    scopus 로고
    • Alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway
    • Lee JW, Juliano RL. 2000. Alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway. Mol Biol Cell 11:1973-1987.
    • (2000) Mol Biol Cell , vol.11 , pp. 1973-1987
    • Lee, J.W.1    Juliano, R.L.2
  • 28
    • 0034647341 scopus 로고    scopus 로고
    • Osteoprotegerin is an alpha v beta 3-induced, NF-kappa B-dependent survival factor for endothelial cells
    • Malyankar UM, Scatena M, Suchland KL, Yun TJ, Clark EA, Giachelli CM. 2000. Osteoprotegerin is an alpha v beta 3-induced, NF-kappa B-dependent survival factor for endothelial cells. J Biol Chem 275:20959-20962.
    • (2000) J Biol Chem , vol.275 , pp. 20959-20962
    • Malyankar, U.M.1    Scatena, M.2    Suchland, K.L.3    Yun, T.J.4    Clark, E.A.5    Giachelli, C.M.6
  • 29
    • 0035958902 scopus 로고    scopus 로고
    • A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription
    • Matter ML, Ruoslahti E. 2001. A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription. J Biol Chem 276:27757-27763.
    • (2001) J Biol Chem , vol.276 , pp. 27757-27763
    • Matter, M.L.1    Ruoslahti, E.2
  • 31
    • 0033600722 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein
    • Pugazhenthi S, Miller E, Sable C, Young P, Heidenreich KA, Boxer LM, Reusch JE. 1999. Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein. J Biol Chem 274:27529-27535.
    • (1999) J Biol Chem , vol.274 , pp. 27529-27535
    • Pugazhenthi, S.1    Miller, E.2    Sable, C.3    Young, P.4    Heidenreich, K.A.5    Boxer, L.M.6    Reusch, J.E.7
  • 33
    • 0037071893 scopus 로고    scopus 로고
    • Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription
    • Redmond L, Kashani AH, Ghosh A. 2002. Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription. Neuron 34:999-1010.
    • (2002) Neuron , vol.34 , pp. 999-1010
    • Redmond, L.1    Kashani, A.H.2    Ghosh, A.3
  • 35
  • 36
    • 0024836021 scopus 로고
    • Isolation and characterization of Chinese hamster ovary cell variants deficient in the expression of fibronectin receptor
    • Schreiner CL, Bauer JS, Danilov YN, Hussein S, Sczekan MM, Juliano RL. 1989. Isolation and characterization of Chinese hamster ovary cell variants deficient in the expression of fibronectin receptor. J Cell Biol 109:3157-3167.
    • (1989) J Cell Biol , vol.109 , pp. 3157-3167
    • Schreiner, C.L.1    Bauer, J.S.2    Danilov, Y.N.3    Hussein, S.4    Sczekan, M.M.5    Juliano, R.L.6
  • 37
    • 0033137329 scopus 로고    scopus 로고
    • The Ca-calmodulin-dependent protein kinase cascade
    • Soderling TR. 1999. The Ca-calmodulin-dependent protein kinase cascade. Trends Biochem Sci 24:232-236.
    • (1999) Trends Biochem Sci , vol.24 , pp. 232-236
    • Soderling, T.R.1
  • 38
    • 0034717285 scopus 로고    scopus 로고
    • Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60
    • Sonoda Y, Matsumoto Y, Funakoshi M, Yamamoto D, Hanks SK, Kasahara T. 2000. Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60. J Biol Chem 275:16309-16315.
    • (2000) J Biol Chem , vol.275 , pp. 16309-16315
    • Sonoda, Y.1    Matsumoto, Y.2    Funakoshi, M.3    Yamamoto, D.4    Hanks, S.K.5    Kasahara, T.6
  • 39
    • 0030038229 scopus 로고    scopus 로고
    • Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis
    • Stromblad S, Becker JC, Yebra M, Brooks PC, Cheresh DA. 1996. Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis. J Clin Invest 98:426-433.
    • (1996) J Clin Invest , vol.98 , pp. 426-433
    • Stromblad, S.1    Becker, J.C.2    Yebra, M.3    Brooks, P.C.4    Cheresh, D.A.5
  • 40
    • 0030068660 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinases type I, II, and IV
    • 2+/ calmodulin-dependent protein kinases type I, II, and IV. J Biol Chem 271:3066-3073.
    • (1996) J Biol Chem , vol.271 , pp. 3066-3073
    • Sun, P.1    Lou, L.2    Maurer, R.A.3
  • 41
    • 0033575287 scopus 로고    scopus 로고
    • PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway
    • Tamura M, Gu J, Danen EH, Takino T, Miyamoto S, Yamada KM. 1999. PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway. J Biol Chem 274:20693-20703.
    • (1999) J Biol Chem , vol.274 , pp. 20693-20703
    • Tamura, M.1    Gu, J.2    Danen, E.H.3    Takino, T.4    Miyamoto, S.5    Yamada, K.M.6
  • 42
    • 0037025313 scopus 로고    scopus 로고
    • Beta 1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway
    • Tian B, Lessan K, Kahm J, Kleidon J, Henke C. 2002. Beta 1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway. J Biol Chem 277:24667-24675.
    • (2002) J Biol Chem , vol.277 , pp. 24667-24675
    • Tian, B.1    Lessan, K.2    Kahm, J.3    Kleidon, J.4    Henke, C.5
  • 43
    • 0030584077 scopus 로고    scopus 로고
    • The adaptor protein She couples a class of integrins to the control of cell cycle progression
    • Wary KK, Mainiero F, Isakoff SJ, Marcantonio EE, Giancotti FG. 1996. The adaptor protein She couples a class of integrins to the control of cell cycle progression. Cell 87:733-743.
    • (1996) Cell , vol.87 , pp. 733-743
    • Wary, K.K.1    Mainiero, F.2    Isakoff, S.J.3    Marcantonio, E.E.4    Giancotti, F.G.5
  • 44
    • 0032483575 scopus 로고    scopus 로고
    • A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth
    • Wary KK, Mariotti A, Zurzolo C, Giancotti FG. 1998. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 94:625-634.
    • (1998) Cell , vol.94 , pp. 625-634
    • Wary, K.K.1    Mariotti, A.2    Zurzolo, C.3    Giancotti, F.G.4
  • 45
    • 0027175838 scopus 로고
    • The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin
    • Zhang Z, Morla AO, Vuori K, Bauer JS, Juliano RL, Ruoslahti E. 1993. The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin. J Cell Biol 122:235-242.
    • (1993) J Cell Biol , vol.122 , pp. 235-242
    • Zhang, Z.1    Morla, A.O.2    Vuori, K.3    Bauer, J.S.4    Juliano, R.L.5    Ruoslahti, E.6
  • 46
    • 0028983407 scopus 로고
    • The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression
    • Zhang Z, Vuori K, Reed JC, Ruoslahti E. 1995. The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proc Natl Acad Sci USA 92:6161-6165.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6161-6165
    • Zhang, Z.1    Vuori, K.2    Reed, J.C.3    Ruoslahti, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.