-
1
-
-
0032768206
-
Hepatitis C virus: Current understanding and prospects for future therapies
-
Rosen HR, Gretch DR. Hepatitis C virus: current understanding and prospects for future therapies. Mol Med Today 1999;5:393-9.
-
(1999)
Mol Med Today
, vol.5
, pp. 393-399
-
-
Rosen, H.R.1
Gretch, D.R.2
-
2
-
-
7044272621
-
Pathogenesis of hepatitis C-associated hepatocellular carcinoma
-
Liang TJ, Heller T. Pathogenesis of hepatitis C-associated hepatocellular carcinoma. Gastroenterology 2004;127:S62-71.
-
(2004)
Gastroenterology
, vol.127
-
-
Liang, T.J.1
Heller, T.2
-
3
-
-
0344443242
-
Replication of the hepatitis C virus in cell culture
-
Bartenschlager R, Kaul A, Sparacio S. Replication of the hepatitis C virus in cell culture. Antiviral Res 2003;60:91-102.
-
(2003)
Antiviral Res
, vol.60
, pp. 91-102
-
-
Bartenschlager, R.1
Kaul, A.2
Sparacio, S.3
-
4
-
-
8944262349
-
Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype
-
Ray RB, Lagging LM, Meyer K, Ray R. Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. J Virol 1996;70:4438-43.
-
(1996)
J Virol
, vol.70
, pp. 4438-4443
-
-
Ray, R.B.1
Lagging, L.M.2
Meyer, K.3
Ray, R.4
-
5
-
-
0031712813
-
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
-
Moriya K, Fujie H, Shintani Y, et al. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med 1998;4:1065-7.
-
(1998)
Nat Med
, vol.4
, pp. 1065-1067
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
-
6
-
-
1942436893
-
Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein
-
Kao CF, Chen SY, Chen JY, Wu Lee YH. Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein. Oncogene 2004;23:2472-83.
-
(2004)
Oncogene
, vol.23
, pp. 2472-2483
-
-
Kao, C.F.1
Chen, S.Y.2
Chen, J.Y.3
Wu Lee, Y.H.4
-
7
-
-
0034602420
-
Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability
-
Otsuka mol/L, Kato N, Lan K, et al. Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability. J Biol Chem 2000;275:34122-30.
-
(2000)
J Biol Chem
, vol.275
, pp. 34122-34130
-
-
Otsuka, M.L.1
Kato, N.2
Lan, K.3
-
8
-
-
0034043749
-
Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells
-
Honda M, Kaneko S, Shimazaki T, et al. Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells. Hepatology 2000;31:1351-9.
-
(2000)
Hepatology
, vol.31
, pp. 1351-1359
-
-
Honda, M.1
Kaneko, S.2
Shimazaki, T.3
-
9
-
-
0030589563
-
Suppression of apoptotic cell death by hepatitis C virus core protein
-
Ray RB, Meyer K, Ray R. Suppression of apoptotic cell death by hepatitis C virus core protein. Virology 1996;226:176-82.
-
(1996)
Virology
, vol.226
, pp. 176-182
-
-
Ray, R.B.1
Meyer, K.2
Ray, R.3
-
10
-
-
0030891710
-
Transcriptional repression of p53 promoter by hepatitis C virus core protein
-
Ray RB, Steele R, Meyer K, Ray R. Transcriptional repression of p53 promoter by hepatitis C virus core protein. J Biol Chem 1997;272:10983-6.
-
(1997)
J Biol Chem
, vol.272
, pp. 10983-10986
-
-
Ray, R.B.1
Steele, R.2
Meyer, K.3
Ray, R.4
-
12
-
-
0041662272
-
Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence
-
Takaoka A, Hayakawa S, Yanai H, et al. Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence. Nature 2003;424:516-23.
-
(2003)
Nature
, vol.424
, pp. 516-523
-
-
Takaoka, A.1
Hayakawa, S.2
Yanai, H.3
-
13
-
-
0038108598
-
Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity
-
Herzer K, Falk CS, Encke J, et al. Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity. J Virol 2003;77:8299-309.
-
(2003)
J Virol
, vol.77
, pp. 8299-8309
-
-
Herzer, K.1
Falk, C.S.2
Encke, J.3
-
15
-
-
0037169341
-
The role of PML in tumor suppression
-
Salomoni P, Pandolfi PP. The role of PML in tumor suppression. Cell 2002;108:165-70.
-
(2002)
Cell
, vol.108
, pp. 165-170
-
-
Salomoni, P.1
Pandolfi, P.P.2
-
17
-
-
0030027449
-
Analysis of the growth and transformation suppressor domains of promyelocytic leukemia gene, PML
-
Le XF, Yang P, Chang KS. Analysis of the growth and transformation suppressor domains of promyelocytic leukemia gene, PML. J Biol Chem 1996;271:130-5.
-
(1996)
J Biol Chem
, vol.271
, pp. 130-135
-
-
Le, X.F.1
Yang, P.2
Chang, K.S.3
-
18
-
-
0034669124
-
Regulation of p53 activity in nuclear bodies by a specific PML isoform
-
Fogal V, Gostissa M, Sandy P, et al. Regulation of p53 activity in nuclear bodies by a specific PML isoform. EMBO J 2000;19:6185-95.
-
(2000)
EMBO J
, vol.19
, pp. 6185-6195
-
-
Fogal, V.1
Gostissa, M.2
Sandy, P.3
-
19
-
-
0034306019
-
The function of PML in p53-dependent apoptosis
-
Guo A, Salomoni P, Luo J, et al. The function of PML in p53-dependent apoptosis. Nat Cell Biol 2000;2:730-6.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 730-736
-
-
Guo, A.1
Salomoni, P.2
Luo, J.3
-
20
-
-
0031791875
-
PML is essential for multiple apoptotic pathways
-
Wang ZG, Ruggero D, Ronchetti S, et al. PML is essential for multiple apoptotic pathways. Nat Genet 1998;20:266-72.
-
(1998)
Nat Genet
, vol.20
, pp. 266-272
-
-
Wang, Z.G.1
Ruggero, D.2
Ronchetti, S.3
-
21
-
-
0035969127
-
Role and fate of PML nuclear bodies in response to interferon and viral infections
-
Regad T, Chelbi-Alix MK. Role and fate of PML nuclear bodies in response to interferon and viral infections. Oncogene 2001;20:7274-86.
-
(2001)
Oncogene
, vol.20
, pp. 7274-7286
-
-
Regad, T.1
Chelbi-Alix, M.K.2
-
22
-
-
0035969103
-
DNA viruses and viral proteins that interact with PML nuclear bodies
-
Everett RD. DNA viruses and viral proteins that interact with PML nuclear bodies. Oncogene 2001;20:7266-73.
-
(2001)
Oncogene
, vol.20
, pp. 7266-7273
-
-
Everett, R.D.1
-
23
-
-
0346147033
-
Body language: The function of PML nuclear bodies in apoptosis regulation
-
Hofmann TG, Will H. Body language: the function of PML nuclear bodies in apoptosis regulation. Cell Death Differ 2003;10:1290-9.
-
(2003)
Cell Death Differ
, vol.10
, pp. 1290-1299
-
-
Hofmann, T.G.1
Will, H.2
-
24
-
-
0035969125
-
PML protein isoforms and the RBCC/TRIM motif
-
Jensen K, Shiels C, Freemont PS. PML protein isoforms and the RBCC/TRIM motif. Oncogene 2001;20:7223-33.
-
(2001)
Oncogene
, vol.20
, pp. 7223-7233
-
-
Jensen, K.1
Shiels, C.2
Freemont, P.S.3
-
25
-
-
0034644274
-
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
-
Pearson M, Carbone R, Sebastiani C, et al. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature 2000;406:207-10.
-
(2000)
Nature
, vol.406
, pp. 207-210
-
-
Pearson, M.1
Carbone, R.2
Sebastiani, C.3
-
26
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain- interacting protein kinase-2
-
Hofmann TG, Moller A, Sirma H, et al. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol 2002;4:1-10.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 1-10
-
-
Hofmann, T.G.1
Moller, A.2
Sirma, H.3
-
27
-
-
0034663873
-
PML is induced by oncogenic ras and promotes premature senescence
-
Ferbeyre G, de Stanchina E, Querido E, Baptiste N, Prives C, Lowe SW. PML is induced by oncogenic ras and promotes premature senescence. Genes Dev 2000;14:2015-27.
-
(2000)
Genes Dev
, vol.14
, pp. 2015-2027
-
-
Ferbeyre, G.1
De Stanchina, E.2
Querido, E.3
Baptiste, N.4
Prives, C.5
Lowe, S.W.6
-
28
-
-
0031743648
-
P53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller M, Wilder S, Bannasch D, et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 1998;188:2033-45.
-
(1998)
J Exp Med
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
-
29
-
-
0036510121
-
A polymorphic microsatellite that mediates induction of PIG3 by p53
-
Contente A, Dittmer A, Koch MC, Roth J, Dobbelstein M. A polymorphic microsatellite that mediates induction of PIG3 by p53. Nat Genet 2002;30:315-20.
-
(2002)
Nat Genet
, vol.30
, pp. 315-320
-
-
Contente, A.1
Dittmer, A.2
Koch, M.C.3
Roth, J.4
Dobbelstein, M.5
-
30
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
31
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991;139:271-9.
-
(1991)
J Immunol Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
32
-
-
0036237039
-
Oncogenic ras and p53 cooperate to induce cellular senescence
-
Ferbeyre G, de Stanchina E, Lin AW, et al. Oncogenic ras and p53 cooperate to induce cellular senescence. Mol Cell Biol 2002;22:3497-508.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3497-3508
-
-
Ferbeyre, G.1
De Stanchina, E.2
Lin, A.W.3
-
33
-
-
0036847998
-
PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2
-
Yang S, Kuo C, Bisi JE, Kim MK. PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2. Nat Cell Biol 2002;4:865-70.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 865-870
-
-
Yang, S.1
Kuo, C.2
Bisi, J.E.3
Kim, M.K.4
-
34
-
-
18244379872
-
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
-
D'Orazi G, Cecchinelli B, Bruno T, et al. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol 2002;4:11-9.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 11-19
-
-
D'Orazi, G.1
Cecchinelli, B.2
Bruno, T.3
-
35
-
-
2942711737
-
HPV E6 proteins interact with specific PML isoforms and allow distinctions to be made between different POD structures
-
Guccione E, Lethbridge KJ, Killick N, Leppard KN, Banks L. HPV E6 proteins interact with specific PML isoforms and allow distinctions to be made between different POD structures. Oncogene 2004;23:4662-72.
-
(2004)
Oncogene
, vol.23
, pp. 4662-4672
-
-
Guccione, E.1
Lethbridge, K.J.2
Killick, N.3
Leppard, K.N.4
Banks, L.5
-
36
-
-
1342291118
-
Loss of the tumor suppressor PML in human cancers of multiple histologic origins
-
Gurrieri C, Capodieci P, Bernardi R, et al. Loss of the tumor suppressor PML in human cancers of multiple histologic origins. J Natl Cancer Inst 2004;96:269-79.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 269-279
-
-
Gurrieri, C.1
Capodieci, P.2
Bernardi, R.3
-
37
-
-
1542285168
-
PML is a direct p53 target that modulates p53 effector functions
-
de Stanchina E, Querido E, Narita M, et al. PML is a direct p53 target that modulates p53 effector functions. Mol Cell 2004;13:523-35.
-
(2004)
Mol Cell
, vol.13
, pp. 523-535
-
-
Stanchina, E.1
Querido, E.2
Narita, M.3
-
39
-
-
0029618165
-
Induction of the PML protein by interferons in normal and APL cells
-
Chelbi-Alix MK, Pelicano L, Quignon F, et al. Induction of the PML protein by interferons in normal and APL cells. Leukemia 1995;9:2027-33.
-
(1995)
Leukemia
, vol.9
, pp. 2027-2033
-
-
Chelbi-Alix, M.K.1
Pelicano, L.2
Quignon, F.3
|