Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity

Journal of Virology

Volumn 77, Issue 15, 2003, Pages 8299-8309

  Herzer, Kerstin ^a   Falk, Christine S ^c   Encke, Jens ^b   Eichhorst, Sören T ^d   Ulsenheimer, Axel ^e   Seliger, Barbara ^f   Krammer, Peter H ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

^f JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CORE PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MUTANT PROTEIN; PROTEIN P53; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL ACTIVITY; CHRONIC HEPATITIS; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DOWN REGULATION; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSFECTION; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; LIVER CELL; MOLECULAR RECOGNITION; NATURAL KILLER CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN INDUCTION; UPREGULATION; WILD TYPE;

ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; HEPACIVIRUS; HEPATITIS C, CHRONIC; HEPATOCYTES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; KILLER CELLS, NATURAL; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION; VIRAL CORE PROTEINS;

EID: 0038108598     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.15.8299-8309.2003     Document Type: Article

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