메뉴 건너뛰기




Volumn 2, Issue 1, 2005, Pages 21-27

Selecting effective siRNA target sequences for mammalian genes

Author keywords

Gene degradation; Gene silencing; RNAi; siRNA; siRNA guideline; Target sequence

Indexed keywords

CYCLIN B1; NUCLEOTIDE; SMALL INTERFERING RNA;

EID: 27744539021     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.2.1.1404     Document Type: Article
Times cited : (9)

References (68)
  • 1
    • 0035281741 scopus 로고    scopus 로고
    • RNA interference-2001
    • Sharp PA. RNA interference-2001. Genes Dev 2001; 15:485-90.
    • (2001) Genes Dev , vol.15 , pp. 485-490
    • Sharp, P.A.1
  • 2
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391:806-11.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 3
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494-8.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 4
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001; 15:188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 5
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
    • Holen T, Amarzguioui M, Wiiger MT, Babaie E, Prydz H. Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res 2002; 30:1757-66.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wiiger, M.T.3    Babaie, E.4    Prydz, H.5
  • 6
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 2001; 20:6877-88.
    • (2001) EMBO J , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 7
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 2002; 26:199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 8
    • 0037686295 scopus 로고    scopus 로고
    • Killing the messenger: Short RNAs that silence gene expression
    • Dykxhoorn DM, Navia CD, Sharp PA. Killing the messenger: Short RNAs that silence gene expression. Nature Review 2003; 4:457-67.
    • (2003) Nature Review , vol.4 , pp. 457-467
    • Dykxhoorn, D.M.1    Navia, C.D.2    Sharp, P.A.3
  • 9
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ. RNA interference. Nature 2002; 418:244-51.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 12
    • 1642273831 scopus 로고    scopus 로고
    • An algorithm for selection of functional siRNA sequences
    • Amarzguioui M, Prydz H. An algorithm for selection of functional siRNA sequences. Biochem Biophys Res Commun 2004; 316:1050-8.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 1050-1058
    • Amarzguioui, M.1    Prydz, H.2
  • 13
    • 2342564353 scopus 로고    scopus 로고
    • A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens
    • Hsieh AC, Bo R, Monola J, Vazquez F, Bare O, Khvorova A, Scaringe S, Sellers WR. A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens. Nucleic Acids Res 2004; 32:893-901.
    • (2004) Nucleic Acids Res , vol.32 , pp. 893-901
    • Hsieh, A.C.1    Bo, R.2    Monola, J.3    Vazquez, F.4    Bare, O.5    Khvorova, A.6    Scaringe, S.7    Sellers, W.R.8
  • 15
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • Khvorova A, Reynold A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003; 115:209-16.
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynold, A.2    Jayasena, S.D.3
  • 18
    • 0037421189 scopus 로고    scopus 로고
    • Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway
    • Goshima G, Kiyomitsu T, Yoda K, Yanagida M. Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. J Cell Biol 2003; 160:25-39.
    • (2003) J Cell Biol , vol.160 , pp. 25-39
    • Goshima, G.1    Kiyomitsu, T.2    Yoda, K.3    Yanagida, M.4
  • 19
    • 3542992506 scopus 로고    scopus 로고
    • An effective method for selecting siRNA target sequences in mammalian cells
    • Takasaki S, Kotani S, Konagaya A. An effective method for selecting siRNA target sequences in mammalian cells. Cell Cycle 2004; 3:790-5.
    • (2004) Cell Cycle , vol.3 , pp. 790-795
    • Takasaki, S.1    Kotani, S.2    Konagaya, A.3
  • 21
    • 0141703274 scopus 로고    scopus 로고
    • Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase
    • USA
    • Mahajan KN, Mitchell BS. Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase. Proc Natl Acad Sci USA 2003; 100:10746-51.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 10746-10751
    • Mahajan, K.N.1    Mitchell, B.S.2
  • 22
    • 0242413645 scopus 로고    scopus 로고
    • Effect of clathrin heavy chain- and -adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in hela cells
    • Hinrichsen L, Harborth J, Andrees L, Weber K, Ungewickell EJ. Effect of clathrin heavy chain- and -adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in hela cells. J Biol Chem 2003; 278:45160-70.
    • (2003) J Biol Chem , vol.278 , pp. 45160-45170
    • Hinrichsen, L.1    Harborth, J.2    Andrees, L.3    Weber, K.4    Ungewickell, E.J.5
  • 24
    • 0141730323 scopus 로고    scopus 로고
    • siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells
    • Karin Butz, Tutik Ristriani, Arnd Hengstermann, Claudia Denk, Martin Scheffher, Felix Hoppe-Seyler. siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells. Oncogene 2003; 22:5938-45.
    • (2003) Oncogene , vol.22 , pp. 5938-5945
    • Butz, K.1    Ristriani, T.2    Hengstermann, A.3    Denk, C.4    Scheffher, M.5    Hoppe-Seyler, F.6
  • 25
    • 0041920922 scopus 로고    scopus 로고
    • The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses
    • McCown M, Diamond MS, Pekosz A. The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses. Virology 2003; 313:514-24.
    • (2003) Virology , vol.313 , pp. 514-524
    • McCown, M.1    Diamond, M.S.2    Pekosz, A.3
  • 26
    • 0242580234 scopus 로고    scopus 로고
    • PAC-SIN3 Binds ADAM12/Meltrin and Upregulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor
    • Mori S, Tanaka M, Nanba D, Nishiwaki E, Ishiguro H, Higashiyama S, Matsuura N. PAC-SIN3 Binds ADAM12/Meltrin and Upregulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor. J Biol Chem 2003; 278:46029-34.
    • (2003) J Biol Chem , vol.278 , pp. 46029-46034
    • Mori, S.1    Tanaka, M.2    Nanba, D.3    Nishiwaki, E.4    Ishiguro, H.5    Higashiyama, S.6    Matsuura, N.7
  • 27
    • 0142091755 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus protein expression by RNA interference
    • Sen A, Steele R, Ghosh AK, Basu A, Ray R, Ray RB. Inhibition of hepatitis C virus protein expression by RNA interference. Virus Res 2003; 96:27-35.
    • (2003) Virus Res , vol.96 , pp. 27-35
    • Sen, A.1    Steele, R.2    Ghosh, A.K.3    Basu, A.4    Ray, R.5    Ray, R.B.6
  • 28
    • 0041923781 scopus 로고    scopus 로고
    • Selective inhibition of hepatitis B virus replication by RNA interference
    • Ying C, Clercq ED, Neyts J. Selective inhibition of hepatitis B virus replication by RNA interference. Biochem. Biophys Res Commun 2003; 309:482-4.
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 482-484
    • Ying, C.1    Clercq, E.D.2    Neyts, J.3
  • 29
    • 0142123020 scopus 로고    scopus 로고
    • Gene silencing in chick embryos with a vector-based small interfering RNA system
    • Katahira T, Nakamura H. Gene silencing in chick embryos with a vector-based small interfering RNA system. Devel Growth Different 2003; 45:361-7.
    • (2003) Devel Growth Different , vol.45 , pp. 361-367
    • Katahira, T.1    Nakamura, H.2
  • 30
    • 0042838272 scopus 로고    scopus 로고
    • Use of adeno-associated viral vector for delivery of small interfering RNA
    • Tomar RS, Matta H, Chaudhary PM. Use of adeno-associated viral vector for delivery of small interfering RNA. Oncogene 2003; 22:5712-5.
    • (2003) Oncogene , vol.22 , pp. 5712-5715
    • Tomar, R.S.1    Matta, H.2    Chaudhary, P.M.3
  • 31
    • 17344384999 scopus 로고    scopus 로고
    • Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus
    • Enünlü I, Pápai G, Cserpán I, Udvardy A, Jeang KT, Boros I. Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus. Biochem Biophys Res Commun 2003; 309:44-51.
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 44-51
    • Enünlü, I.1    Pápai, G.2    Cserpán, I.3    Udvardy, A.4    Jeang, K.T.5    Boros, I.6
  • 32
    • 0141793844 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 activates TERT gene transcription through induction of c-Myc and release of USF-mediated repression
    • McMurray HR, McCance DJ. Human papillomavirus type 16 E6 activates TERT gene transcription through induction of c-Myc and release of USF-mediated repression. J Virol 2003; 77:9852-61.
    • (2003) J Virol , vol.77 , pp. 9852-9861
    • McMurray, H.R.1    McCance, D.J.2
  • 33
    • 0242321836 scopus 로고    scopus 로고
    • Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains
    • Yoshida Y, Tokunaga F, Chiba T, Iwai K, Tanaka K, Tai T. Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains. J Biol Chem 2003; 278:43877-84.
    • (2003) J Biol Chem , vol.278 , pp. 43877-43884
    • Yoshida, Y.1    Tokunaga, F.2    Chiba, T.3    Iwai, K.4    Tanaka, K.5    Tai, T.6
  • 35
    • 0042887572 scopus 로고    scopus 로고
    • Transient RNA interference in hematopoietic progenitors with functional consequences
    • Oliveira DM, Goodell MA. Transient RNA interference in hematopoietic progenitors with functional consequences. Genesis 2003; 36:203-8.
    • (2003) Genesis , vol.36 , pp. 203-208
    • Oliveira, D.M.1    Goodell, M.A.2
  • 39
    • 0142211228 scopus 로고    scopus 로고
    • Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway
    • Calipel A, Lefevre G, Pouponnot C, Mouriaux F, Eychène A, Mascarelli F. Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway. J Biol Chem 2003; 278:42409-18.
    • (2003) J Biol Chem , vol.278 , pp. 42409-42418
    • Calipel, A.1    Lefevre, G.2    Pouponnot, C.3    Mouriaux, F.4    Eychène, A.5    Mascarelli, F.6
  • 40
    • 0142149161 scopus 로고    scopus 로고
    • Protein phosphatase 2A associates with Rb2/p130 and mediates retinoic acid-induced growth suppression of ovarian carcinoma cells
    • Vuocolo S, Purev E, Zhang D, Bartek J, Hansen K, Soprano DR, Soprano KJ. Protein phosphatase 2A associates with Rb2/p130 and mediates retinoic acid-induced growth suppression of ovarian carcinoma cells. J Biol Chem 2003; 278:41881-9.
    • (2003) J Biol Chem , vol.278 , pp. 41881-41889
    • Vuocolo, S.1    Purev, E.2    Zhang, D.3    Bartek, J.4    Hansen, K.5    Soprano, D.R.6    Soprano, K.J.7
  • 41
    • 0142149092 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein-binding protein cloned by a yeast two-hybrid system
    • Sugawara T, Shimizu H, Hoshi N, Nakajima A, Fujimoto S. Steroidogenic acute regulatory protein-binding protein cloned by a yeast two-hybrid system. J Biol Chem 2003; 278:42487-94.
    • (2003) J Biol Chem , vol.278 , pp. 42487-42494
    • Sugawara, T.1    Shimizu, H.2    Hoshi, N.3    Nakajima, A.4    Fujimoto, S.5
  • 42
    • 0041633807 scopus 로고    scopus 로고
    • Apoptosis induction in prostate cancer cells and xenografts by combined treatment with apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand and CPT-11
    • Ray S, Almasan A. Apoptosis induction in prostate cancer cells and xenografts by combined treatment with apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand and CPT-11. Cancer Res 2003; 63:4713-23.
    • (2003) Cancer Res , vol.63 , pp. 4713-4723
    • Ray, S.1    Almasan, A.2
  • 43
    • 0142135190 scopus 로고    scopus 로고
    • Chromogranin B-induced secretory granule biogenesis: Comparison with the similar role of chromogranin A
    • Huh YH, Jeon SH, Yoo SH. Chromogranin B-induced secretory granule biogenesis: Comparison with the similar role of chromogranin A. J Biol Chem 2003; 278:40581-9.
    • (2003) J Biol Chem , vol.278 , pp. 40581-40589
    • Huh, Y.H.1    Jeon, S.H.2    Yoo, S.H.3
  • 46
    • 0042132030 scopus 로고    scopus 로고
    • Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (Taxol)-exposed cells
    • Burns TF, Fei P, Scata KA, Dicker DT, El-Deiry WS. Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (Taxol)-exposed cells. Mol Cell Biol 2003; 23:5556-71.
    • (2003) Mol Cell Biol , vol.23 , pp. 5556-5571
    • Burns, T.F.1    Fei, P.2    Scata, K.A.3    Dicker, D.T.4    El-Deiry, W.S.5
  • 47
    • 0141994776 scopus 로고    scopus 로고
    • Early growth response gene 1 modulates androgen receptor signaling in prostate carcinoma cells
    • Yang SZ, Abdulkadir SA. Early growth response gene 1 modulates androgen receptor signaling in prostate carcinoma cells. J Biol Chem 2003; 278:39906-11.
    • (2003) J Biol Chem , vol.278 , pp. 39906-39911
    • Yang, S.Z.1    Abdulkadir, S.A.2
  • 48
    • 0042161890 scopus 로고    scopus 로고
    • The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides
    • Far RKK, Sczakiel G. The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides. Nucleic Acids Res 2003; 31:4417-24.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4417-4424
    • Far, R.K.K.1    Sczakiel, G.2
  • 49
    • 0042924332 scopus 로고    scopus 로고
    • Short interfering RNA-mediated interference of gene expression and viral DNA accumulation in cultured plant cells
    • USA
    • Vanitharani R, Chellappan P, Fauquet CM. Short interfering RNA-mediated interference of gene expression and viral DNA accumulation in cultured plant cells. Proc Natl Acad Sci USA 2003; 100:9632-6.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 9632-9636
    • Vanitharani, R.1    Chellappan, P.2    Fauquet, C.M.3
  • 50
    • 0141994778 scopus 로고    scopus 로고
    • The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged
    • Ding Q, Stewart Jr J, Olman MA, Klobe MR, Gladson CL. The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged. J Biol Chem 2003; 278:39882-91.
    • (2003) J Biol Chem , vol.278 , pp. 39882-39891
    • Ding, Q.1    Stewart Jr., J.2    Olman, M.A.3    Klobe, M.R.4    Gladson, C.L.5
  • 51
    • 0037811261 scopus 로고    scopus 로고
    • VIPL, a VIP36-like membrane protein with a putative function in the export of glycoproteins from the endoplasmic reticulum
    • Neve EPA, Svensson K, Fuxe J, Ralf F, Pettersson RF. VIPL, a VIP36-like membrane protein with a putative function in the export of glycoproteins from the endoplasmic reticulum. Experimental Cell Res 2003; 288:70-83.
    • (2003) Experimental Cell Res , vol.288 , pp. 70-83
    • Neve, E.P.A.1    Svensson, K.2    Fuxe, J.3    Ralf, F.4    Pettersson, R.F.5
  • 52
    • 0042242786 scopus 로고    scopus 로고
    • Absence of adhesion triggers differential FAK and SAPKp38 signals in SW620 human colon cancer cells that may inhibit adhesiveness and lead to cell death
    • Walsh M, Thamilselvan V, Grotelueschen R, Farhana L, Basson M. Absence of adhesion triggers differential FAK and SAPKp38 signals in SW620 human colon cancer cells that may inhibit adhesiveness and lead to cell death. Cell Physiol Biochem 2003; 13:135-46.
    • (2003) Cell Physiol Biochem , vol.13 , pp. 135-146
    • Walsh, M.1    Thamilselvan, V.2    Grotelueschen, R.3    Farhana, L.4    Basson, M.5
  • 53
    • 0141643206 scopus 로고    scopus 로고
    • The PDZ protein tax-interacting protein-1 inhibits β-catenin transcriptional activity and growth of colorectal cancer cells
    • Kanamori M, Sandy P, Marzinotto S, Benetti R, Kai C, Hayashizaki Y, Schneider C, Suzuki H. The PDZ protein tax-interacting protein-1 inhibits β-catenin transcriptional activity and growth of colorectal cancer cells. J Biol Chem 2003; 278:38758-64.
    • (2003) J Biol Chem , vol.278 , pp. 38758-38764
    • Kanamori, M.1    Sandy, P.2    Marzinotto, S.3    Benetti, R.4    Kai, C.5    Hayashizaki, Y.6    Schneider, C.7    Suzuki, H.8
  • 54
    • 0042674380 scopus 로고    scopus 로고
    • Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H
    • Laposa RR, Feeney L, Cleaver JE. Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H. Cancer Res 2003; 63:3909-12.
    • (2003) Cancer Res , vol.63 , pp. 3909-3912
    • Laposa, R.R.1    Feeney, L.2    Cleaver, J.E.3
  • 55
    • 0042592941 scopus 로고    scopus 로고
    • The N-CoR/Histone deacetylase 3 complex is required for repression by thyroid hormone receptor
    • Ishizuka T, Lazar MA. The N-CoR/Histone deacetylase 3 complex is required for repression by thyroid hormone receptor. Mol Cell Biol 2003; 23:5122-31.
    • (2003) Mol Cell Biol , vol.23 , pp. 5122-5131
    • Ishizuka, T.1    Lazar, M.A.2
  • 57
    • 0042744677 scopus 로고    scopus 로고
    • NFATc1 with AP-3 site binding specificity mediates gene expression of prostate-specific-membrane-antigen
    • Lee SJ, Lee K, Yang X, Jung C, Gardner T, Kim H, Jeng M, Kao C. NFATc1 with AP-3 site binding specificity mediates gene expression of prostate-specific-membrane-antigen. J Mol Biol 2003; 330:749-60.
    • (2003) J Mol Biol , vol.330 , pp. 749-760
    • Lee, S.J.1    Lee, K.2    Yang, X.3    Jung, C.4    Gardner, T.5    Kim, H.6    Jeng, M.7    Kao, C.8
  • 59
    • 0141481046 scopus 로고    scopus 로고
    • Munc18 interacting proteins: Adp-ribosylation factor-dependent coat proteins that regulate the traffic of β-alzheimer's precursor protein
    • Hill K, Li Y, Bennett M, McKay M, Zhu X, Shern J, Torre E, Lah JJ, Levey AI, Richard A, Kahn RA. Munc18 interacting proteins: Adp-ribosylation factor-dependent coat proteins that regulate the traffic of β-alzheimer's precursor protein. J Biol Chem 2003; 278:36032-40.
    • (2003) J Biol Chem , vol.278 , pp. 36032-36040
    • Hill, K.1    Li, Y.2    Bennett, M.3    McKay, M.4    Zhu, X.5    Shern, J.6    Torre, E.7    Lah, J.J.8    Levey, A.I.9    Richard, A.10    Kahn, R.A.11
  • 60
    • 0038756442 scopus 로고    scopus 로고
    • Use of RNA interference to target cyclin E-overexpressing hepatocellular carcinoma
    • Li K, Lin SY, Brunicardi FC, Seu P. Use of RNA interference to target cyclin E-overexpressing hepatocellular carcinoma. Cancer Res 2003; 63:3593-7.
    • (2003) Cancer Res , vol.63 , pp. 3593-3597
    • Li, K.1    Lin, S.Y.2    Brunicardi, F.C.3    Seu, P.4
  • 61
    • 0141483389 scopus 로고    scopus 로고
    • GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2
    • Zhao C, Ma H, Bossy-Wetzel E, Lipton SA, Zhang Z, Feng GS. GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2. J Biol Chem 2003; 278:34641-53.
    • (2003) J Biol Chem , vol.278 , pp. 34641-34653
    • Zhao, C.1    Ma, H.2    Bossy-Wetzel, E.3    Lipton, S.A.4    Zhang, Z.5    Feng, G.S.6
  • 62
    • 0141445962 scopus 로고    scopus 로고
    • Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability
    • Johnson KR, Johnson KY, Becker KP, Bielawski J, Mao C, Obeid LM. Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability. J Biol Chem 2003; 278:34541-7.
    • (2003) J Biol Chem , vol.278 , pp. 34541-34547
    • Johnson, K.R.1    Johnson, K.Y.2    Becker, K.P.3    Bielawski, J.4    Mao, C.5    Obeid, L.M.6
  • 64
    • 0038408486 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion
    • Liu L, Chang H, Chiang L, Hung W. Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. Cancer Res 2003; 63:3069-72.
    • (2003) Cancer Res , vol.63 , pp. 3069-3072
    • Liu, L.1    Chang, H.2    Chiang, L.3    Hung, W.4
  • 65
    • 0041529686 scopus 로고    scopus 로고
    • Protein kinase a blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras
    • Dumaz N, Richard Marais R. Protein kinase a blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras. J Biol Chem 2003; 278:29819-23.
    • (2003) J Biol Chem , vol.278 , pp. 29819-29823
    • Dumaz, N.1    Richard Marais, R.2
  • 66
    • 0043234465 scopus 로고    scopus 로고
    • An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated at cells
    • Wang X, Khadpe J, Hu B, Iliakis G, Wang Y. An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated at cells. J Biol Chem 2003; 278:30869-74.
    • (2003) J Biol Chem , vol.278 , pp. 30869-30874
    • Wang, X.1    Khadpe, J.2    Hu, B.3    Iliakis, G.4    Wang, Y.5
  • 67
    • 0038813736 scopus 로고    scopus 로고
    • Stop codon suppression via inhibition of eRF1 expression
    • Carnes J, Jacobson M, Leinwand L, Yarus M. Stop codon suppression via inhibition of eRF1 expression. RNA 2003; 9:648-53.
    • (2003) RNA , vol.9 , pp. 648-653
    • Carnes, J.1    Jacobson, M.2    Leinwand, L.3    Yarus, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.