PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression

Molecular Cell

Volumn 1, Issue 3, 1998, Pages 371-380

  Kotani, Shuji ^a   Tugendreich, Stuart ^b   Fujii, Mika ^a   Jorgensen, Pia Marie ^c   Watanabe, Nobumoto ^a   Hoog, Christer ^c   Hieter, Philip ^b   Todokoro, Kazuo ^a  

^a RIKEN TSUKUBA INSTITUTE   (Japan)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPC1 PROTEIN, MOUSE; CDC16 PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; HISTIDINE; MATURATION PROMOTING FACTOR; MULTIENZYME COMPLEX; ONCOPROTEIN; POLO LIKE KINASE 1; POLO-LIKE KINASE 1; PROTEIN; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; UBIQUITIN;

ANAPHASE; ANIMAL; ARTICLE; CELL STRAIN 3T3; CYTOLOGY; ELECTROPHORESIS; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; METAPHASE; MITOSIS; MOUSE; PHOSPHORYLATION; PHYSIOLOGY;

3T3 CELLS; ANAPHASE; ANIMALS; CELL CYCLE PROTEINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTROPHORESIS; ENZYME ACTIVATION; HISTIDINE; MATURATION-PROMOTING FACTOR; METAPHASE; MICE; MITOSIS; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; UBIQUITINS;

EID: 0031991880     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80037-4     Document Type: Article

References (60)

1. Amon, A., Irniger, S., and Nasmyth, K. (1994). Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. Cell 77, 1037-1050.
2. Brandeis, M., and Hunt, T. (1996). The proteolysis of mitotic cyclin in mammalian cells persists from the end of mitosis until the onset of S phase. EMBO J. 15, 5280-5289.
3. Ciechanover, A. (1994). The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21.
4. Cohen-Fix, O., Peters, J.M., Kirschner, M.W., and Koshland, D. (1996). Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev. 10, 3081-3093.
5. Costa, M., Gerner, E.W., and Russell, D.H. (1976). Cell cycle-specific activity of type I and type II cyclic adenosine 3′:5′-monophosphate-dependent protein kinases in chinese hamster ovary cells. J. Biol. Chem. 251, 3313-3319.
6. Davis, F.M., Tsao, T.Y., Fowler, S.K., and Rao, P.N. (1983). Monoclonal antibodies to mitotic cells. Proc. Natl. Acad. Sci. USA 80, 2926-2930.
7. Descombes, P., and Nigg, E.A. (1998). The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. EMBO J., in press.
8. Fenton, B., and Glover, D.M. (1993). A conserved mitotic kinase active at late anaphase-telophase in syncytial Drosophila embryos. Nature 363, 637-640.
9. Funabiki, H., Yamano, H., Kumada, K., Nagao, K., Hunt, T., and Yanagida, M. (1996). Cut2 proteolysis required for sister-chromatid separation in fission yeast. Nature 381, 438-441.
10. Glotzer, M., Murray, A.W., and Kirschner, M.W. (1991). Cyclin is degraded by the ubiquitin pathway. Nature 349, 132-138.
11. Glover, D.M., Ohkura, H., and Tavares, A. (1996). A polo kinase: the choreographer of the mitotic stage? J. Cell Biol. 135, 1681-1684.
12. Golsteyn, R.M., Schultz, S.J., Bartek, J., Ziemiecki, A., Ried, T., and Nigg, E.A. (1994). Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5. J. Cell Sci. 107, 1509-1517.
13. Golsteyn, R.M., Mundt, K.E., Fry, A.M., and Nigg, E.A. (1995). Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. J. Cell Biol. 129, 1617-1628.
14. Guacci, V., Koshland, D., and Strunnikov, A. (1997). A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. Cell 91, 47-57.
15. Hamanaka, R., Maloid, S., Smith, M.R., O'Connell, C.D., Longo, D.L., and Ferris, D.K. (1994). Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase. Cell Growth Differ. 5, 249-257.
16. Hartwell, L.H., Mortimer, R.K., Culotti, J., and Culotti, M. (1977). Genetic control of the cell division cycle in yeast V: genetic analysis of cdc mutants. Genetics 74, 267-286.
17. He, X., Patterson, T.E., and Sazer, S. (1997). The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex. Proc. Natl. Acad. Sci. USA 94, 7965-7970.
18. Hershko, A., Ganoth, D., Sudakin, V., Dahan, A., Cohen, L.H., Luca, F.C., Ruderman, J.V., and Eytan, E. (1994). Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2. J. Biol. Chem. 269, 4940-4946.
19. Holloway, S.L., Glotzer, M., King, R.W., and Murray, A.W. (1993). Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell 73, 1393-1402.
20. Irniger, S., and Nasmyth, K. (1997). The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase. J. Cell Sci. 110, 1523-1531.
21. Irniger, S., Piatti, S., Michaelis, C., and Nasmyth, K. (1995). Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81, 269-277.
22. Ishii, K., Kumada, K., Toda, T., and Yanagida, M. (1996). Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+. EMBO J. 15, 6629-6640.
23. King, R.W., Jackson, P.K., and Kirschner, M.W. (1994). Mitosis in transition. Cell 79, 563-571.
24. King, R.W., Peters, J.M., Tugendreich, S., Rolfe, M., Hieter, P., and Kirschner, M.W. (1995). A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81, 279-288.
25. King, R.W., Deshaies, R.J., Peters, J.-M., and Kirschner, M.W. (1996). How proteolysis drives the cell cycle. Science 274, 1652-1659.
26. Kitada, K., Johnson, A.L., Johnston, L.H., and Sugino, A. (1993). A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Mol. Cell. Biol. 13, 4445-4457.
27. Kumagai, A., and Dunphy, W.G. (1996). Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts. Science 273, 1377-1380.
28. Lahav-Baratz, S., Sudakin, V., Ruderman, J., and Hershko, A. (1995). Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase. Proc. Natl. Acad. Sci. USA 92, 9303-9307.
29. Lamb, J.R., Michaud, W.A., Sikorski, R.S., and Hieter, P.A. (1994). Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis. EMBO J. 13, 4321-4328.
30. Lane, H.A., and Nigg, E.A. (1996). Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes. J. Cell Biol. 135, 1701-1713.
31. Lee, K.S., Yuan, Y.-L.O., Kuriyama, R., and Erikson, R. (1995). Plk is an M-phase-specific protein kinase and interacts with a kinesin-like protein, CHO-1/MKLP-1. Mol. Cell. Biol. 15, 7143-7151.
32. Li, F.N., and Johnston, M. (1997). Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle. EMBO J. 16, 5629-5638.
33. Li, Y., Gorbea, C., Mahaffey, D., Rechsteiner, M., and Benezra, R. (1997). MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Proc. Natl. Acad. Sci. USA 94, 12431-12436.
34. Llamazares, S., Moreira, A., Tavares, A., Girdham, C., Spruce, B.A., Gonzalez, C., Karess, R.E., Glover, D.M., and Sunkel, C.E. (1991). polo encodes a protein kinase homolog required for mitosis in Drosophila. Genes Dev. 5, 2153-2165.
35. Michaelis, C., Ciosk, R., and Nasmyth, K. (1997). Cohesions:chromosomal proteins that prevent premature separation of sister chromatids. Cell 91, 35-45.
36. Murray, A. (1995). Cyclin ubiquitination: the destructive end of mitosis. Cell 81, 149-152.
37. Murray, A.W., Solomon, M.J., and Kirschner, M.W. (1989). The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature 339, 280-286.
38. Nigg, E.A., Schafer, G., Hilz, H., and Eppenberger, H.M. (1985). Cyclic-AMP-dependent protein kinase type II is associated with the golgi complex and with centrosomes. Cell 41, 1039-1051.
39. Ohkura, H., Hagan, I.M., and Glover, D.M. (1995). The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells. Genes Dev. 9, 1059-1073.
40. Page, A.M., and Hieter, P.A. (1997). The anaphase-promoting complex. In Cancer Surveys Vol. 29: Checkpoint Controls and Cancer, M.B. Kastan, ed. (New York: Cold Spring Harbor Laboratory Press), pp. 133-150.
41. Peters, J.M., King, R.W., Hoog, C., and Kirschner, M.W. (1996). Identification of BIME as asubunit of the anaphase-promoting complex. Science 274, 1199-1201.
42. Schwab, M., Schultze-Lutum, A., and Seufert, W. (1997). Yeast Hct1 is a regulator of Clb2 cyclin proteolysis. Cell 90, 683-693.
43. Shirayama, M., Zachariae, W., Ciosk, R., and Nasmyth, K. (1998). The polo-like kinase Cdc5p and the WD-repeat protein Cdc20/Fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. EMBO J., in press.
44. Sigrist, S.J., and Lehner, C.F. (1997). Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. Cell 90, 671-681.
45. Skowyra, D., Craig, K.L., Tyers, M., Elledge, S.J., and Harper, J.W. (1997). F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91, 209-219.
46. Starborg, M., Brundell, E., Gell, K., and Hoog, C. (1994). A novel murine gene encoding a 216-kDa protein is related to a mitotic checkpoint regulator previously identified in Aspergillus nidulans. J. Biol. Chem. 269, 24133-24137.
47. Sudakin, V., Ganoth, D., Dahan, A., Heller, H., Hershko, J., Luca, F.C., Ruderman, J.V., and Hershko, A. (1995). The cyclosome, a large complex containing cyclin-sensitive ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell 6, 185-197.
48. Sunkel, C.E., and Glover, D.M. (1988). polo, a mitotic mutant of Drosophila displaying abnormal spindle poles. J. Cell Sci. 89, 25-38.
49. Surana, U., Amon, A., Dowzer, C., McGrew, J., Byers, B., and Nasmyth, K. (1993). Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J. 12, 1969-1978.
50. Tavares, A.A., Glover, D.M., and Sunkel, C.E. (1996). The conserved mitotic kinase polo is regulated by phosphorylation and has preferred microtuble-associated substrates in Drosophila embryo extracts. EMBO J. 15, 4873-4883.
51. Toczyski, D.P., Galgoczy, D.J., and Hartwell, L.H. (1997). CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell 90, 1097-1106.
52. Todokoro, K., Kanazawa, S., Amanuma, H., and Ikawa, Y. (1987). Specific binding of erythropoietin to its receptor on responsive mouse erythroleukemia cells. Proc. Natl. Acad. Sci. USA 84, 4126-4130.
53. Townsley, F.M., Aristarkhov, A., Beck, S., Hershko, A., and Ruderman, J.V. (1997). Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase. Proc. Natl. Acad. Sci. USA 94, 2362-2367.
54. Tugendreich, S., Tomkiel, J., Earnshaw, W., and Hieter, P. (1995). CDC27HS colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. Cell 81, 261-268.
55. Visintin, R., Prinz, S., and Amon, A. (1997). CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278, 460-463.
56. Westendorf, J.M., Rao, P.N., and Gerace, L. (1994).Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc. Natl. Acad. Sci. USA 91, 714-718.
57. Yamada, H., Kumada, K., and Yanagida, M. (1997). Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/ cyclosome required for anaphase in fission yeast. J. Cell Sci. 110, 1793-1804.
58. Yamashita, Y.M., Nakaseko, Y., Samejima, I., Kumada, K., Yamada, H., Michaelson, D., and Yanagida, M. (1996). 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway. Nature 384, 276-279.
59. Zachariae, W., Shin, T.H., Galova, M., Obermaier, B., and Nasmyth, K. (1996). Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science 274, 1201-1204.
60. Zhong, H., SuYang, H., Erdjument-Bromage, H., Tempst, P., and Ghosh, S. (1997). The transcriptional activity of NF-κB is regulated bythe IκB-associated PKAc subunit through acyclic AMP-independent mechanism. Cell 89, 413-424.