-
1
-
-
11144334098
-
Recombinant protein therapeutics- success rates, market trends and values to 2010
-
A.K. Pavlou, and J.M. Reichert Recombinant protein therapeutics- success rates, market trends and values to 2010 Nat Biotechnol 22 2004 1513 1519
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1513-1519
-
-
Pavlou, A.K.1
Reichert, J.M.2
-
2
-
-
0346216863
-
Chemical and biological properties of polymer-modified proteins
-
G.G. Kochendoerfer Chemical and biological properties of polymer-modified proteins Expert Opin Biol Ther 3 2003 1253 1261
-
(2003)
Expert Opin Biol Ther
, vol.3
, pp. 1253-1261
-
-
Kochendoerfer, G.G.1
-
3
-
-
0037362655
-
Effect of pegylation on pharmaceuticals
-
J.M. Harris, and R.B. Chess Effect of pegylation on pharmaceuticals Nat Rev Drug Discov 2 2003 214 221 Excellent review of protein PEGylation, and its clinical application. The structure and development paths of major approved polymer-modified proteins are discussed.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 214-221
-
-
Harris, J.M.1
Chess, R.B.2
-
4
-
-
0038387390
-
The Dawning era of polymer therapeutics
-
R. Duncan The Dawning era of polymer therapeutics Nat Rev Drug Discov 2 2003 347 360 Excellent review of the application of polymers to drug delivery.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 347-360
-
-
Duncan, R.1
-
5
-
-
0023683508
-
Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers
-
M.J. Knauf, D.P. Bell, P. Hirtzer, Z.P. Luo, J.D. Young, and N.V. Katre Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers J Biol Chem 263 1988 15064 15070
-
(1988)
J Biol Chem
, vol.263
, pp. 15064-15070
-
-
Knauf, M.J.1
Bell, D.P.2
Hirtzer, P.3
Luo, Z.P.4
Young, J.D.5
Katre, N.V.6
-
6
-
-
0033654389
-
Modulation of the pharmacokinetics and pharmacodynamics of proteins by polyethylene glycol conjugation
-
R. Mehvar Modulation of the pharmacokinetics and pharmacodynamics of proteins by polyethylene glycol conjugation J Pharm Pharm Sci 3 2000 125 136
-
(2000)
J Pharm Pharm Sci
, vol.3
, pp. 125-136
-
-
Mehvar, R.1
-
8
-
-
0017701219
-
Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
-
A. Abuchowski, T. Van Es, N.C. Palczuk, and F.F. Davis Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol J Biol Chem 252 1977 3578 3581
-
(1977)
J Biol Chem
, vol.252
, pp. 3578-3581
-
-
Abuchowski, A.1
Van Es, T.2
Palczuk, N.C.3
Davis, F.F.4
-
9
-
-
0025128987
-
Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol
-
N.V. Katre Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol J Immunol 144 1990 209 213
-
(1990)
J Immunol
, vol.144
, pp. 209-213
-
-
Katre, N.V.1
-
10
-
-
0026124772
-
The therapeutic value of polyethylene glycol-modified proteins
-
M.L. Nucci, R. Shorr, and A. Abuchowski The therapeutic value of polyethylene glycol-modified proteins Adv Drug Deliv Rev 6 1991 133 151
-
(1991)
Adv Drug Deliv Rev
, vol.6
, pp. 133-151
-
-
Nucci, M.L.1
Shorr, R.2
Abuchowski, A.3
-
11
-
-
0001365675
-
Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth a sarcoma model
-
N.V. Katre, M.J. Knauf, and W.J. Laird Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model Proc Natl Acad Sci USA 84 1987 1487 1491
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 1487-1491
-
-
Katre, N.V.1
Knauf, M.J.2
Laird, W.J.3
-
12
-
-
0035086519
-
Rational design of a potent, long-lasting form of interferon: A 40 kDa branched polyethylene glycol-conjugated interferon α-2a for the treatment of hepatitis C
-
P. Bailon, A. Palleroni, C.A. Schaffer, C.L. Spence, W.J. Fung, J.E. Porter, G.K. Ehrlich, W. Pan, Z.X. Xu, and M.W. Modi Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon α-2a for the treatment of hepatitis C Bioconjug Chem 12 2001 195 202
-
(2001)
Bioconjug Chem
, vol.12
, pp. 195-202
-
-
Bailon, P.1
Palleroni, A.2
Schaffer, C.A.3
Spence, C.L.4
Fung, W.J.5
Porter, J.E.6
Ehrlich, G.K.7
Pan, W.8
Xu, Z.X.9
Modi, M.W.10
-
13
-
-
0028343321
-
Modification of recombinant human granulocyte colony-stimulating factor (rhG-CSF) and its derivative ND 28 with polyethylene glycol
-
M. Yamasaki, M. Asano, M. Okabe, M. Morimoto, and Y. Yokoo Modification of recombinant human granulocyte colony-stimulating factor (rhG-CSF) and its derivative ND 28 with polyethylene glycol J Biochem (Tokyo) 115 1994 814 819
-
(1994)
J Biochem (Tokyo)
, vol.115
, pp. 814-819
-
-
Yamasaki, M.1
Asano, M.2
Okabe, M.3
Morimoto, M.4
Yokoo, Y.5
-
14
-
-
0028047803
-
Chemical modification of natural human tumor necrosis factor-alpha with polyethylene glycol increases its anti-tumor potency
-
Y. Tsutsumi, T. Kihira, S. Yamamoto, K. Kubo, S. Nakagawa, M. Miyake, Y. Horisawa, T. Kanamori, H. Ikegami, and T. Mayumi Chemical modification of natural human tumor necrosis factor-alpha with polyethylene glycol increases its anti-tumor potency Jpn J Cancer Res 85 1994 9 12
-
(1994)
Jpn J Cancer Res
, vol.85
, pp. 9-12
-
-
Tsutsumi, Y.1
Kihira, T.2
Yamamoto, S.3
Kubo, K.4
Nakagawa, S.5
Miyake, M.6
Horisawa, Y.7
Kanamori, T.8
Ikegami, H.9
Mayumi, T.10
-
15
-
-
9544220647
-
Long-acting growth hormones produced by conjugation with polyethylene glycol
-
R. Clark, K. Olson, G. Fuh, M. Marian, D. Mortensen, G. Teshima, S. Chang, H. Chu, V. Mukku, and E. Canova_Davis Long-acting growth hormones produced by conjugation with polyethylene glycol J Biol Chem 271 1996 21969 21977
-
(1996)
J Biol Chem
, vol.271
, pp. 21969-21977
-
-
Clark, R.1
Olson, K.2
Fuh, G.3
Marian, M.4
Mortensen, D.5
Teshima, G.6
Chang, S.7
Chu, H.8
Mukku, V.9
Canova Davis, E.10
-
16
-
-
0032146861
-
Chemical protein synthesis
-
J. Wilken, and S.B.H. Kent Chemical protein synthesis Curr Opin Biotechnol 9 1998 412 426 Excellent review of the history of chemoselective ligation approaches.
-
(1998)
Curr Opin Biotechnol
, vol.9
, pp. 412-426
-
-
Wilken, J.1
Kent, S.B.H.2
-
18
-
-
0033791223
-
Synthesis of native proteins by chemical ligation
-
P.E. Dawson, and S.B.H. Kent Synthesis of native proteins by chemical ligation Annu Rev Biochem 69 2000 923 962
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 923-962
-
-
Dawson, P.E.1
Kent, S.B.H.2
-
19
-
-
0345742616
-
A new strategy for the synthesis of glycoproteins
-
Z. Zhang, J. Gildersleeve, Y-Y. Yang, R. Xu, J.A. Loo, S. Uryu, C-H. Wong, and P.G. Schultz A new strategy for the synthesis of glycoproteins Science 303 2004 371 373 Site-specific incorporation of glyco-amino acid building blocks into recombinant proteins in E. coli.
-
(2004)
Science
, vol.303
, pp. 371-373
-
-
Zhang, Z.1
Gildersleeve, J.2
Yang, Y.-Y.3
Xu, R.4
Loo, J.A.5
Uryu, S.6
Wong, C.-H.7
Schultz, P.G.8
-
20
-
-
0041520960
-
An expanded eukaryotic genetic code
-
J.W. Chin, T.A. Cropp, J.C. Anderson, M. Mukherji, Z. Zhang, and P.G. Schultz An expanded eukaryotic genetic code Science 301 2003 964 967
-
(2003)
Science
, vol.301
, pp. 964-967
-
-
Chin, J.W.1
Cropp, T.A.2
Anderson, J.C.3
Mukherji, M.4
Zhang, Z.5
Schultz, P.G.6
-
23
-
-
12444305299
-
Site-specific PEGylation of a lysine-deficient TNF-α with full bioactivity
-
Y. Yamamoto, Y. Tsutsumi, Y. Yoshioka, T. Nishibata, K. Kobayashi, T. Okamoto, Y. Mukai, T. Shimizu, S. Nakagawa, and S. Nagata Site-specific PEGylation of a lysine-deficient TNF-α with full bioactivity Nat Biotechnol 21 2003 546 552
-
(2003)
Nat Biotechnol
, vol.21
, pp. 546-552
-
-
Yamamoto, Y.1
Tsutsumi, Y.2
Yoshioka, Y.3
Nishibata, T.4
Kobayashi, K.5
Okamoto, T.6
Mukai, Y.7
Shimizu, T.8
Nakagawa, S.9
Nagata, S.10
-
24
-
-
12344260516
-
A long-acting, highly potent interferon α-2 conjugate created using site-specific PEGylation
-
M.S. Rosendahl, D.H. Doherty, D.J. Smith, S.J. Carlson, E.A. Chlipala, and G.N. Cox A long-acting, highly potent interferon α-2 conjugate created using site-specific PEGylation Bioconjug Chem 16 2005 200 207
-
(2005)
Bioconjug Chem
, vol.16
, pp. 200-207
-
-
Rosendahl, M.S.1
Doherty, D.H.2
Smith, D.J.3
Carlson, S.J.4
Chlipala, E.A.5
Cox, G.N.6
-
25
-
-
0029759584
-
Characterization and stability of N-terminally PEGylated rhG-CSF
-
O.B. Kinstler, D.N. Brems, S.L. Lauren, A.G. Paige, J.B. Hamburger, and M.J. Treuheit Characterization and stability of N-terminally PEGylated rhG-CSF Pharm Res 13 1996 996 1002
-
(1996)
Pharm Res
, vol.13
, pp. 996-1002
-
-
Kinstler, O.B.1
Brems, D.N.2
Lauren, S.L.3
Paige, A.G.4
Hamburger, J.B.5
Treuheit, M.J.6
-
27
-
-
0028231302
-
Facile synthesis of homogeneous artificial proteins
-
K. Rose Facile synthesis of homogeneous artificial proteins J Am Chem Soc 116 1994 30 33
-
(1994)
J Am Chem Soc
, vol.116
, pp. 30-33
-
-
Rose, K.1
-
28
-
-
0036000120
-
Total chemical synthesis of a 27 kDa TASP protein derived from the MscL ion channel of M. tuberculosis by ketoxime-forming ligation
-
G.G. Kochendoerfer, J.M. Tack, and S. Cressman Total chemical synthesis of a 27 kDa TASP protein derived from the MscL ion channel of M. tuberculosis by ketoxime-forming ligation Bioconjug Chem 13 2002 474 480
-
(2002)
Bioconjug Chem
, vol.13
, pp. 474-480
-
-
Kochendoerfer, G.G.1
Tack, J.M.2
Cressman, S.3
-
29
-
-
0030059104
-
Site-specific attachment of functionalized poly(ethylene glycol) to the amino terminus of proteins
-
H.F. Gaertner, and R.E. Offord Site-specific attachment of functionalized poly(ethylene glycol) to the amino terminus of proteins Bioconjug Chem 7 1996 38 44
-
(1996)
Bioconjug Chem
, vol.7
, pp. 38-44
-
-
Gaertner, H.F.1
Offord, R.E.2
-
30
-
-
0026857064
-
Construction of protein analogs by site-specific condensation of unprotected fragments
-
H.F. Gaertner, K. Rose, R. Cotton, D. Timms, R. Camble, and R.E. Offord Construction of protein analogs by site-specific condensation of unprotected fragments Bioconjug Chem 3 1992 262 268
-
(1992)
Bioconjug Chem
, vol.3
, pp. 262-268
-
-
Gaertner, H.F.1
Rose, K.2
Cotton, R.3
Timms, D.4
Camble, R.5
Offord, R.E.6
-
31
-
-
0037423148
-
Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein
-
G.G. Kochendoerfer, S.Y. Chen, F. Mao, S. Cressman, S. Traviglia, H. Shao, C.L. Hunter, D.W. Low, E.N. Cagle, and M. Carnevali Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein Science 299 2003 884 887 Total synthesis of a 51 kDa protein-polymer conjugate by purely chemical means. This protein product candidate has entered Phase 1 clinical trials.
-
(2003)
Science
, vol.299
, pp. 884-887
-
-
Kochendoerfer, G.G.1
Chen, S.Y.2
Mao, F.3
Cressman, S.4
Traviglia, S.5
Shao, H.6
Hunter, C.L.7
Low, D.W.8
Cagle, E.N.9
Carnevali, M.10
-
32
-
-
20144371341
-
Synthetic erythropoietic proteins: Tuning biological performance by site-specific polymer attachment
-
S.-Y. Chen, S. Cressman, F. Mao, H. Shao, D.W. Low, H.S. Beilan, E.N. Cagle, M. Carnevali, V. Gueriguian, and P.J. Keogh Synthetic erythropoietic proteins: Tuning biological performance by site-specific polymer attachment Chem Biol 12 2005 371 383
-
(2005)
Chem Biol
, vol.12
, pp. 371-383
-
-
Chen, S.-Y.1
Cressman, S.2
Mao, F.3
Shao, H.4
Low, D.W.5
Beilan, H.S.6
Cagle, E.N.7
Carnevali, M.8
Gueriguian, V.9
Keogh, P.J.10
-
33
-
-
13444301106
-
Site-specific polymer attachment to a CCL-5 (RANTES) analogue by oxime exchange
-
H. Shao, M.M. Crnogorac, T. Kong, S-Y. Chen, J.M. Williams, J.M. Tack, V. Gueriguian, E.N. Cagle, M. Carnevali, and D. Tumelty Site-specific polymer attachment to a CCL-5 (RANTES) analogue by oxime exchange J Am Chem Soc 127 2005 1350 1351 Polymer attachment to a chemokine modifies aggregation.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 1350-1351
-
-
Shao, H.1
Crnogorac, M.M.2
Kong, T.3
Chen, S.-Y.4
Williams, J.M.5
Tack, J.M.6
Gueriguian, V.7
Cagle, E.N.8
Carnevali, M.9
Tumelty, D.10
-
34
-
-
27744463965
-
-
Polymer Conjugates of Interferon-beta With Enhanced Biological Potency. PCT Publication WO 2004/0126361.
-
Saifer MGP, Martinez AL, Williams LD, Sherman MR: Polymer Conjugates of Interferon-beta With Enhanced Biological Potency. PCT Publication WO 2004/0126361.
-
-
-
Saifer, M.G.P.1
Martinez, A.L.2
Williams, L.D.3
Sherman, M.R.4
-
35
-
-
27744499573
-
-
Methods and Kits for Making Polypeptides Having a Single Covalently Bound N-terminal Water-Soluble Polymer. US Patent 2000, 6,077,939.
-
Wei Z, Menon-Rudolph S, Ghosh-Dastidar P: Methods and Kits for Making Polypeptides Having a Single Covalently Bound N-terminal Water-Soluble Polymer. US Patent 2000, 6,077,939.
-
-
-
Wei, Z.1
Menon-Rudolph, S.2
Ghosh-Dastidar, P.3
-
36
-
-
0029787761
-
Site-specific protein modification using a ketone handle
-
V.W. Cornish, K.M. Hahn, and P.G. Schultz Site-specific protein modification using a ketone handle J Am Chem Soc 118 1996 8150 8151
-
(1996)
J Am Chem Soc
, vol.118
, pp. 8150-8151
-
-
Cornish, V.W.1
Hahn, K.M.2
Schultz, P.G.3
-
37
-
-
0037422608
-
Addition of the keto functional group to the genetic code of Escherichia coli
-
L. Wang, Z. Zhang, A. Brock, and P.G. Schultz Addition of the keto functional group to the genetic code of Escherichia coli Proc Natl Acad Sci USA 100 2003 56 61 Addition of the ketone functionality to proteins in E. coli enables the recombinant production of pharmaceutical proteins for subsequent site-specific polymer attachment.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 56-61
-
-
Wang, L.1
Zhang, Z.2
Brock, A.3
Schultz, P.G.4
-
38
-
-
0034677879
-
Cell surface engineering by a modified Staudinger reaction
-
E. Saxon, and C.R. Bertozzi Cell surface engineering by a modified Staudinger reaction Science 287 2000 2007 2010
-
(2000)
Science
, vol.287
, pp. 2007-2010
-
-
Saxon, E.1
Bertozzi, C.R.2
-
39
-
-
0034729576
-
Staudinger ligation: A peptide from a thioester and azide
-
B.L. Nilsson, L.L. Kiessling, and R.T. Raines Staudinger ligation: a peptide from a thioester and azide Org Lett 2 2000 1939 1941
-
(2000)
Org Lett
, vol.2
, pp. 1939-1941
-
-
Nilsson, B.L.1
Kiessling, L.L.2
Raines, R.T.3
-
40
-
-
0034643993
-
A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds
-
E. Saxon, J.I. Armstrong, and C.R. Bertozzi A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds Org Lett 2 2000 2141 2143
-
(2000)
Org Lett
, vol.2
, pp. 2141-2143
-
-
Saxon, E.1
Armstrong, J.I.2
Bertozzi, C.R.3
-
41
-
-
4644256655
-
C-terminal site-specific PEGylation of a truncated thrombomodulin mutant with retention of full bioactivity
-
C.S. Cazalis, C.A. Haller, L. Sease-Cargo, and E.L. Chaikof C-terminal site-specific PEGylation of a truncated thrombomodulin mutant with retention of full bioactivity Bioconjug Chem 15 2004 1005 1009
-
(2004)
Bioconjug Chem
, vol.15
, pp. 1005-1009
-
-
Cazalis, C.S.1
Haller, C.A.2
Sease-Cargo, L.3
Chaikof, E.L.4
-
42
-
-
0037454346
-
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition
-
Q. Wang, T.R. Chan, R. Hilgraf, V.V. Fokin, K.B. Sharpless, and M.G. Finn Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition J Am Chem Soc 125 2003 3192 3193
-
(2003)
J Am Chem Soc
, vol.125
, pp. 3192-3193
-
-
Wang, Q.1
Chan, T.R.2
Hilgraf, R.3
Fokin, V.V.4
Sharpless, K.B.5
Finn, M.G.6
-
43
-
-
7044260692
-
Site-specific PEGylation of proteins containing unnatural amino acids
-
A. Deiters, T.A. Cropp, D. Summerer, M. Mukherji, and P.G. Schultz Site-specific PEGylation of proteins containing unnatural amino acids Bioorg Med Chem Lett 14 2004 5743 5745 Site-specific PEG attachment to a recombinant protein via a specific linkage.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 5743-5745
-
-
Deiters, A.1
Cropp, T.A.2
Summerer, D.3
Mukherji, M.4
Schultz, P.G.5
-
45
-
-
0035804493
-
Native chemical ligation using removable N-α-(1-phenyl-2- mercaptoethyl) auxiliaries
-
P. Botti, M.R. Carrasco, and S.B.H. Kent Native chemical ligation using removable N-α-(1-phenyl-2-mercaptoethyl) auxiliaries Tet Lett 42 2001 1831 1833
-
(2001)
Tet Lett
, vol.42
, pp. 1831-1833
-
-
Botti, P.1
Carrasco, M.R.2
Kent, S.B.H.3
-
46
-
-
0036570182
-
Extending synthetic access to proteins with a removable acyl transfer auxiliary
-
J. Offer, Boddy CNC, and P.E. Dawson Extending synthetic access to proteins with a removable acyl transfer auxiliary J Am Chem Soc 124 2002 4642 4646
-
(2002)
J Am Chem Soc
, vol.124
, pp. 4642-4646
-
-
Offer, J.1
Cnc, B.2
Dawson, P.E.3
-
47
-
-
0035977638
-
Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization
-
L. Yan, and P. Dawson Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization J Am Chem Soc 123 2001 526 533
-
(2001)
J Am Chem Soc
, vol.123
, pp. 526-533
-
-
Yan, L.1
Dawson, P.2
-
48
-
-
1842738226
-
Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis
-
D. Clayton, G. Shapovalov, J.H. Maurer, D.A. Dougherty, H.A. Lester, and G.G. Kochendoerfer Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis Proc Natl Acad Sci USA 101 2004 4764 4769
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4764-4769
-
-
Clayton, D.1
Shapovalov, G.2
Maurer, J.H.3
Dougherty, D.A.4
Lester, H.A.5
Kochendoerfer, G.G.6
-
49
-
-
9344239350
-
Medicinal chemistry applied to a synthetic protein: Development of highly potent HIV entry inhibitors
-
O. Hartley, H. Gaertner, J. Wilken, D. Thompson, R. Fish, A. Ramos, C. Pastore, B. Dufour, F. Cerini, and A. Melotti Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors Proc Natl Acad Sci USA 101 2004 16460 16465
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16460-16465
-
-
Hartley, O.1
Gaertner, H.2
Wilken, J.3
Thompson, D.4
Fish, R.5
Ramos, A.6
Pastore, C.7
Dufour, B.8
Cerini, F.9
Melotti, A.10
-
50
-
-
0032737391
-
Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients
-
I.C. Macdougall, S.J. Gray, O. Elston, C. Breen, B. Jenkins, J. Browne, and J. Egrie Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients J Am Soc Nephrol 10 1999 2392 2395
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 2392-2395
-
-
MacDougall, I.C.1
Gray, S.J.2
Elston, O.3
Breen, C.4
Jenkins, B.5
Browne, J.6
Egrie, J.7
-
51
-
-
0001083017
-
Aminooxy-, hydrazide-, and thiosemicarbazide-functionalized saccharides: Versatile reagents for glycoconjugate synthesis
-
E.C. Rodriguez, L.A. Marcaurelle, and C.R. Bertozzi Aminooxy-, hydrazide-, and thiosemicarbazide-functionalized saccharides: versatile reagents for glycoconjugate synthesis J Org Chem 63 1998 7134 7135
-
(1998)
J Org Chem
, vol.63
, pp. 7134-7135
-
-
Rodriguez, E.C.1
Marcaurelle, L.A.2
Bertozzi, C.R.3
-
52
-
-
0032511944
-
Synthesis of an oxime-linked neoglycopeptide with glycosylation-dependent activity similar to its native counterpart
-
L.A. Marcaurelle, E.C. Rodriguez, and C.R. Bertozzi Synthesis of an oxime-linked neoglycopeptide with glycosylation-dependent activity similar to its native counterpart Tet Lett 39 1998 8417 8420
-
(1998)
Tet Lett
, vol.39
, pp. 8417-8420
-
-
Marcaurelle, L.A.1
Rodriguez, E.C.2
Bertozzi, C.R.3
-
53
-
-
0035961527
-
Chemoselective elaboration of O-linked glycopeptide mimetics by alkylation of 3-thioGalNAc
-
L.A. Marcaurelle, and C.R. Bertozzi Chemoselective elaboration of O-linked glycopeptide mimetics by alkylation of 3-thioGalNAc J Am Chem Soc 123 2001 1587 1595
-
(2001)
J Am Chem Soc
, vol.123
, pp. 1587-1595
-
-
Marcaurelle, L.A.1
Bertozzi, C.R.2
-
54
-
-
0037442330
-
A method for the generation of glycoprotein mimetics
-
H. Liu, L. Wang, A. Brock, C.-H. Wong, and P.G. Schultz A method for the generation of glycoprotein mimetics J Am Chem Soc 125 2003 1702 1703
-
(2003)
J Am Chem Soc
, vol.125
, pp. 1702-1703
-
-
Liu, H.1
Wang, L.2
Brock, A.3
Wong, C.-H.4
Schultz, P.G.5
-
55
-
-
2542548800
-
Toward fully synthetic glycoproteins by ultimately convergent routes: A solution to a long-standing problem
-
J.D. Warren, J.S. Miller, S.J. Keding, and S.J. Danishefsky Toward fully synthetic glycoproteins by ultimately convergent routes: a solution to a long-standing problem J Am Chem Soc 126 2004 6576 6578
-
(2004)
J Am Chem Soc
, vol.126
, pp. 6576-6578
-
-
Warren, J.D.1
Miller, J.S.2
Keding, S.J.3
Danishefsky, S.J.4
-
56
-
-
0033596308
-
Fmoc-based synthesis of peptide-αthioesters: Application to the total chemical synthesis of a glycoprotein by native chemical ligation
-
Y. Shin, K. Winans, B. Backes, S. Kent, J. Ellman, and C. Bertozzi Fmoc-based synthesis of peptide-αthioesters: application to the total chemical synthesis of a glycoprotein by native chemical ligation J Am Chem Soc 121 1999 11684 11689
-
(1999)
J Am Chem Soc
, vol.121
, pp. 11684-11689
-
-
Shin, Y.1
Winans, K.2
Backes, B.3
Kent, S.4
Ellman, J.5
Bertozzi, C.6
-
57
-
-
3543108674
-
Modular assembly of glycoproteins: Towards the synthesis of GlyCAM-1 by using expressed protein ligation
-
D. Macmillan, and C.R. Bertozzi Modular assembly of glycoproteins: towards the synthesis of GlyCAM-1 by using expressed protein ligation Angew Chem Int Ed Engl 43 2004 1355 1359
-
(2004)
Angew Chem Int Ed Engl
, vol.43
, pp. 1355-1359
-
-
MacMillan, D.1
Bertozzi, C.R.2
-
58
-
-
3543095202
-
Cyanogen bromide cleavage generates fragments suitable for expressed protein and glycoprotein ligation
-
D. Macmillan, and L. Arham Cyanogen bromide cleavage generates fragments suitable for expressed protein and glycoprotein ligation J Am Chem Soc 126 2004 9530 9531
-
(2004)
J Am Chem Soc
, vol.126
, pp. 9530-9531
-
-
MacMillan, D.1
Arham, L.2
-
59
-
-
0032782574
-
Total chemical synthesis and high-resolution crystal structure of the potent anti-HIV protein AOP-RANTES
-
J. Wilken, D. Hoover, D.A. Thompson, P.N. Barlow, H. McSparron, L. Picard, A. Wlodawer, J. Lubkowski, and S.B.H. Kent Total chemical synthesis and high-resolution crystal structure of the potent anti-HIV protein AOP-RANTES Chem Biol 6 1999 43 51
-
(1999)
Chem Biol
, vol.6
, pp. 43-51
-
-
Wilken, J.1
Hoover, D.2
Thompson, D.A.3
Barlow, P.N.4
McSparron, H.5
Picard, L.6
Wlodawer, A.7
Lubkowski, J.8
Kent, S.B.H.9
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