Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins

Biochemical and Biophysical Research Communications

Volumn 338, Issue 3, 2005, Pages 1359-1367

  Gustafson, Michael P ^a   Welcker, Markus ^a   Hwang, Harry C ^a   Clurman, Bruce E ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Ebna1 binding protein 2; GSK 3; Myc; RNA processing; Zcchc8

Indexed keywords

ANTIBODY; EBNA 1 BINDING PROTEIN 2; GLYCOGEN SYNTHASE KINASE 3; NUCLEAR PROTEIN; PROTEIN ZCCHC 8; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA DEGRADATION; RNA PROCESSING; STAINING;

CARRIER PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MITOSIS; NUCLEAR PROTEINS; PHOSPHOTHREONINE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-MYC; RNA; RNA-BINDING PROTEINS; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 27744516063     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.090     Document Type: Article

References (38)

1. T. Cardozo, and M. Pagano The SCF ubiquitin ligase: insights into a molecular machine Nat. Rev. Mol. Cell Biol. 5 2004 739 751
2. R.J. Deshaies SCF and Cullin/Ring H2-based ubiquitin ligases Annu. Rev. Cell Dev. Biol. 15 1999 435 467
3. S. Orlicky, X. Tang, A. Willems, M. Tyers, and F. Sicheri Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase Cell 112 2003 243 256
4. M.A. Gregory, Y. Qi, and S.R. Hann Phosphorylation by glycogen synthase kinase-3 controls c-Myc proteolysis and subnuclear localization J. Biol. Chem 278 2003 51606 51612
5. R. Sears, F. Nuckolls, E. Haura, Y. Taya, K. Tamai, and J.R. Nevins Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability Genes Dev. 14 2000 2501 2514
6. M. Welcker, O. Orian, J. Jin, J.A. Grim, J.W. Harper, R.N. Eisenman, and B.E. Clurman The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation Proc. Natl. Acad. Sci. USA 101 2004 9085 9090
7. M. Yada, S. Hatakeyama, T. Kamura, M. Nishiyama, R. Tsuematsu, H. Imaki, N. Ishida, F. Okumura, K. Nakayama, and K.I. Nakayama Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7 EMBO J. 23 2004 2116 2125
8. M. Welcker, A. Orian, J.A. Grim, R.N. Eisenman, and B.E. Clurman A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size Curr. Biol. 26 2004 1852 1857
9. K. Bhatia, K. Huppi, G. Spangler, D. Siwarski, R. Iyer, and I. Magrath Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas Nat. Genet. 5 1993 56 61
10. M. Henriksson, A. Bakardjiev, G. Klein, and B. Luscher Phosphorylation sites mapping in the N-terminal domain of c-Myc modulate its transforming potential Oncogene 8 1993 3199 3209
11. B.J. Pulverer, C. Fisher, K. Vousden, T. Littlewood, G. Evan, and J.R. Woodgett Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo Onocgene 9 1994 59 70
12. T. Yano, C.A. Sander, R.E. Andrade, C.E. Gauwerky, C.M. Croce, D.L. Longo, E.S. Jaffe, and Raffeld Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma Oncogene 8 1993 2741 2748
13. C. Soldani, M.G. Bottone, M. Biggiogera, C. Alpini, A.I. Scovassi, T. Martin, and C. Pellicciari Nuclear localization of phosphorylated c-Myc protein in human tumor cells Eur. J. Histochem. 46 2002 377 380
14. B.E. Clurman, R.J. Sheaff, K. Thress, M. Groudine, and J.M. Roberts Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation Genes Dev. 10 1996 1979 1990
15. A.C. Minella, J. Swanger, E. Bryant, M. Welcker, H. Hwang, and B.E. Clurman p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation Curr. Biol. 12 2002 1817 1827
16. J.S. Andersen, C.E. Lyon, A.H. Fox, A.K. Leung, Y.W. Lam, H. Steen, M. Mann, and A.I. Lamond Directed proteomic analysis of the human nucleolus Curr. Biol. 12 2002 1 11
17. C.L. Gatlin, G.R. Kleeman, L.G. Hays, A.J. Link, and J.R. Yate III Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography-microspray and nanospray mass spectrometry Anal. Biochem. 263 1998 93 101
18. C. Grandori, N. Gomez-Roman, Z.A. Felton-Edkins, C. Ngouenet, D.A. Galloway, R.N. Eisenman, and R.J. White c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I Nat. Cell Biol. 7 2005 311 318
19. A. Arabi, S. Wu, K. Ridderstrale, H. Bierhoff, C. Shiue, K. Fatyol, S. Fahlen, P. Hydbring, O. Soderberg, I. Grummt, L.G. Larsson, and A.P. Wright c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription Nat. Cell Biol. 7 2005 303 310
20. A. Arabi, C. Rustum, E. Hallberg, and A.P.H. Wright Accumulation of c-Myc and proteasomes at the nucleoli of cells containing elevated c-Myc protein levels J. Cell Sci. 116 2003 1707 1717
21. S.M. Prouty, K.D. Hanson, A.L. Boyle, J.R. Brown, M. Shichiri, M.R. Follansbee, W. Kang, and J.M. Sedivy A cell culture model system for genetic analyses of the cell cycle by targeted homologous recombination Oncogene 8 1993 899 907
22. M.D. Huber, J.H. Dworet, K. Shire, L. Frappier, and M.A. McAlear The budding yeast homolog of the human EBNA1-binding protein 2 (Ebp2) is an essential nucleolar protein required for pre-RNA processing J. Biol. Chem. 275 2000 28764 28773
23. P.E. Neiman, A. Ruddell, C. Jasoni, G. Loring, S.J. Thomas, K.A. Brandvold, R.M. Lee, J. Burnside, and J. Delrow Analysis of gene expression during myc oncogene-induced lymphomagenesis in the bursa of Fabricius Proc. Natl. Acad. Sci. 98 2001 6378 6383
24. D. Marinkovic, T. Marinkovic, E. Kokai, T. Barth, P. Moller, and T. Wirth Identification of novel Myc target genes with a potential role in lymphogenesis Nucleic Acids Res. 32 2004 5368 5378
25. C.M. Hedgepeth, M.A. Deardorff, K. Rankin, and P.S. Klein Regulation of glycogen synthase kinase 3 beta and downstream Wnt signaling by axin Mol. Cell Biol. 19 1999 7147 7157
26. O. Puig, F. Caspary, G. Rigaut, B. Rutz, E. Bouveret, E. Bragado-Nilsson, M. Wilm, and B. Seraphin The tandem affinity purification (TAP) method: a general procedure of protein complex purification Methods 24 2001 218 229
27. G. Rigaut, A. Shevchenko, B. Rutz, M. Wilm, M. Mann, and B. Seraphin A generic protein purification method for protein complex characterization and proteome exploration Nat. Biotech. 17 1999 1030 1032
28. A.W. Dangel, L. Shen, A.R. Mendoza, L.C. Wu, and C.Y. Yu Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family Nucleic Acids Res. 23 1995 2120 2126
29. J. de la Cruz, D. Kressler, D. Tollervey, and P. Linder Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae EMBO J. 17 1998 1128 1140
30. J.S. Jacobs Anderson, and R. Parker The 3′ to 5′ degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3′ to 5′ exonuclease of the exosome complex EMBO J. 17 1998 1497 1506
31. B. Lehner, and C.M. Sanderson A protein interaction framework for human mRNA degradation Genome Res. 14 2004 1315 1323
32. P. Mitchell, E. Petfalski, A. Shevchenko, M. Mann, and D. Tollervey The exosome: a conserved eukaryotic RNA processing complex containing multiple 3′ → 5′ exoribonucleases Cell 91 1997 457 466
33. T.L. Western, Y. Cheng, J. Liu, and X. Chen HUA ENHANCER2, a putative DExH-box helicase, maintains hometic B and C gene expression in Arabidopsis Development 129 2002 1569 1581
34. T.B. Guo, L.G. Boros, K.C. Chan, A.P. Hikim, A.P. Hudson, R.S. Swerdloff, A.P. Mitchell, and W.A. Salameh Spermatogenetic expression of RNA-binding motif protein 7, a protein that interacts with splicing factors J. Androl. 24 2003 204 214
35. S. Rousseau, N. Morrice, M. Peggie, D.G. Campbell, M. Gaestel, and P. Cohen Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs EMBO J. 21 2002 6505 6514
36. J. LaCava, J. Houseley, C. Saveanu, E. Petfalski, E. Thompson, A. Jacquier, and D. Tollervey RNA degradation by the exosome is promoted by a nuclear polyadenylation complex Cell 121 2005 713 724
37. D. Mukherjee Gao, J.P. O'Connor, R. Raijmakers, G. Pruijn, C.S. Lutz, and J. Wilusz The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements EMBO J. 21 2002 165 174
38. J. Rappsilber, U. Ryder, A.I. Lamond, and M. Mann Large-scale proteomic analysis of the human spliceosome Genome Res. 12 2002 1231 1245