LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans

Aging Cell

Volumn 4, Issue 5, 2005, Pages 235-245

  Nanji, Manoj ^a   Hopper, Neil A ^b   Gems, David ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Aging; C. elegans; Dauer larva; Insulin IGF 1signaling; Let 60 Ras

Indexed keywords

MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN; SOMATOMEDIN C RECEPTOR; SOMATOMEDIN RECEPTOR; CAENORHABDITIS ELEGANS PROTEIN; DAF 2 PROTEIN, C ELEGANS; DAF-2 PROTEIN, C ELEGANS; INOSITOL 1,4,5 TRISPHOSPHATE; INSULIN; INSULIN RECEPTOR; LET 60 PROTEIN, C ELEGANS; LET-60 PROTEIN, C ELEGANS; SOMATOMEDIN C;

AGING; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DIAPAUSE; EPISTASIS; GENE MUTATION; LARVAL DEVELOPMENT; LONGEVITY; MAMMAL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; ANIMAL MODEL; GENETIC EPISTASIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHENOTYPE; PHYSIOLOGY;

CAENORHABDITIS ELEGANS; MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EPISTASIS, GENETIC; INOSITOL 1,4,5-TRISPHOSPHATE; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MODELS, ANIMAL; PHENOTYPE; RAS PROTEINS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 27744468105     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2005.00166.x     Document Type: Article

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