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Volumn 11, Issue 4, 2005, Pages 295-302

Applications of gene targeting technology to mental retardation and developmental disability research

Author keywords

Conditional knock out; Cre recombinase; Inducible systems; Knock out; Mouse models

Indexed keywords

CRE RECOMBINASE;

EID: 27644545357     PISSN: 10804013     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrdd.20084     Document Type: Review
Times cited : (2)

References (61)
  • 1
    • 5444260773 scopus 로고    scopus 로고
    • Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment
    • Ango F, di Cristo G, Higashiyama H, et al. 2004. Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment. Cell 119:257-272.
    • (2004) Cell , vol.119 , pp. 257-272
    • Ango, F.1    Di Cristo, G.2    Higashiyama, H.3
  • 3
    • 0028246435 scopus 로고
    • Fmr1 knockout mice: A model to study fragile X mental retardation-The Dutch-Belgian Fragile X Consortium
    • Bakker CE, Verheij C, Willemsen R, et al. 1994. Fmr1 knockout mice: a model to study fragile X mental retardation-The Dutch-Belgian Fragile X Consortium. Cell 78:23-33.
    • (1994) Cell , vol.78 , pp. 23-33
    • Bakker, C.E.1    Verheij, C.2    Willemsen, R.3
  • 4
    • 2442506955 scopus 로고    scopus 로고
    • Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor
    • Baquet ZC, Gorski JA, Jones KR. 2004. Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor. J Neurosci 24:4250-4258.
    • (2004) J Neurosci , vol.24 , pp. 4250-4258
    • Baquet, Z.C.1    Gorski, J.A.2    Jones, K.R.3
  • 5
    • 0346503889 scopus 로고    scopus 로고
    • Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice
    • Branda CS, Dymecki SM. 2004. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev Cell 6:7-28.
    • (2004) Dev Cell , vol.6 , pp. 7-28
    • Branda, C.S.1    Dymecki, S.M.2
  • 6
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • Chen RZ, Akbarian S, Tudor M, et al. 2001. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 27:327-331.
    • (2001) Nat Genet , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3
  • 7
    • 0035487293 scopus 로고    scopus 로고
    • Recombineering: A powerful new tool for mouse functional genomics
    • Copeland NG, Jenkins NA, Court DL. 2001. Recombineering: a powerful new tool for mouse functional genomics. Nat Rev Genet 2:769-779.
    • (2001) Nat Rev Genet , vol.2 , pp. 769-779
    • Copeland, N.G.1    Jenkins, N.A.2    Court, D.L.3
  • 8
    • 0036758617 scopus 로고    scopus 로고
    • Doublecortin is required in mice for lamination of the hippocampus but not the neocortex
    • Corbo JC, Deuel TA, Long JM, et al. 2002. Doublecortin is required in mice for lamination of the hippocampus but not the neocortex. J Neurosci 22:7548-7557.
    • (2002) J Neurosci , vol.22 , pp. 7548-7557
    • Corbo, J.C.1    Deuel, T.A.2    Long, J.M.3
  • 9
    • 0033578272 scopus 로고    scopus 로고
    • Behavioral phenotyping of transgenic and knockout mice: Experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests
    • Crawley JN. 1999. Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests. Brain Res 835:18-26.
    • (1999) Brain Res , vol.835 , pp. 18-26
    • Crawley, J.N.1
  • 10
    • 0037609789 scopus 로고    scopus 로고
    • Behavioral phenotyping of rodents
    • Crawley JN. 2003. Behavioral phenotyping of rodents. Comp Med 53:140-146.
    • (2003) Comp Med , vol.53 , pp. 140-146
    • Crawley, J.N.1
  • 11
    • 0034652207 scopus 로고    scopus 로고
    • Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes
    • DiLeone RJ, Marcus GA, Johnson MD, et al. 2000. Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes. Proc Natl Acad Sci USA 97:1612-1617.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1612-1617
    • Dileone, R.J.1    Marcus, G.A.2    Johnson, M.D.3
  • 12
    • 0023630807 scopus 로고
    • Targeted correction of a mutant HPRT gene in mouse embryonic stem cells
    • Doetschman T, Gregg RG, Maeda N, et al. 1987. Targeted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature 330:576-578.
    • (1987) Nature , vol.330 , pp. 576-578
    • Doetschman, T.1    Gregg, R.G.2    Maeda, N.3
  • 14
    • 0033624825 scopus 로고    scopus 로고
    • Locus control regions and epigenetic chromatin modifiers
    • Festenstein R, Kioussis D. 2000. Locus control regions and epigenetic chromatin modifiers. Curr Opin Genet Dev 10:199-203.
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 199-203
    • Festenstein, R.1    Kioussis, D.2
  • 16
    • 0242401835 scopus 로고    scopus 로고
    • A gene expression atlas of the CNS based on bacterial artificial chromosomes
    • Gong S, Zheng C, Doughty ML, et al. 2003. A gene expression atlas of the CNS based on bacterial artificial chromosomes. Nature 425:917-925.
    • (2003) Nature , vol.425 , pp. 917-925
    • Gong, S.1    Zheng, C.2    Doughty, M.L.3
  • 17
    • 0036703466 scopus 로고    scopus 로고
    • Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage
    • Gorski JA, Talley T, Qiu M, et al. 2002. Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage. J Neurosci 22:6309-6314.
    • (2002) J Neurosci , vol.22 , pp. 6309-6314
    • Gorski, J.A.1    Talley, T.2    Qiu, M.3
  • 18
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89:5547-5551.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 19
    • 0029022369 scopus 로고
    • Transcriptional activation by tetracyclines in mammalian cells
    • Gossen M, Freundlieb S, Bender G, et al. 1995. Transcriptional activation by tetracyclines in mammalian cells. Science 268:1766-1769
    • (1995) Science , vol.268 , pp. 1766-1769
    • Gossen, M.1    Freundlieb, S.2    Bender, G.3
  • 20
    • 0037187193 scopus 로고    scopus 로고
    • Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult
    • Gross C, Zhuang X, Stark K, et al. 2002. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 416:396-400.
    • (2002) Nature , vol.416 , pp. 396-400
    • Gross, C.1    Zhuang, X.2    Stark, K.3
  • 21
    • 0036549187 scopus 로고    scopus 로고
    • Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice
    • Gu Y, Mcllwain KL, Weeber EJ, et al. 2002. Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice. J Neurosci 22:2753-2763.
    • (2002) J Neurosci , vol.22 , pp. 2753-2763
    • Gu, Y.1    Mcllwain, K.L.2    Weeber, E.J.3
  • 22
    • 0034607127 scopus 로고    scopus 로고
    • Cre-mediated cerebellum- and hippocampus-restricted gene mutation in mouse brain
    • Guo H, Mao C, Jin XL, et al. 2000. Cre-mediated cerebellum- and hippocampus-restricted gene mutation in mouse brain. Biochem Biophys Res Commun 269:149-154.
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 149-154
    • Guo, H.1    Mao, C.2    Jin, X.L.3
  • 23
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • Guy J, Hendrich B, Holmes M, et al. 2001. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27:322-326.
    • (2001) Nat Genet , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3
  • 24
    • 0029059790 scopus 로고
    • Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
    • Hanks M, Wurst W, Anson-Cartwright L, et al. 1995. Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269:679-682.
    • (1995) Science , vol.269 , pp. 679-682
    • Hanks, M.1    Wurst, W.2    Anson-Cartwright, L.3
  • 25
    • 0035651255 scopus 로고    scopus 로고
    • BAC to the future: The use of BAC transgenic mice for neuroscience research
    • Heintz N. 2001. BAC to the future: the use of BAC transgenic mice for neuroscience research. Nature Rev Neurosci 2:861-870.
    • (2001) Nature Rev Neurosci , vol.2 , pp. 861-870
    • Heintz, N.1
  • 26
    • 11144357454 scopus 로고    scopus 로고
    • Gene expression nervous system atlas (GENSAT)
    • Heintz N. 2004. Gene expression nervous system atlas (GENSAT). Nat Neurosci 7:483.
    • (2004) Nat Neurosci , vol.7 , pp. 483
    • Heintz, N.1
  • 27
    • 0242568295 scopus 로고
    • Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus
    • Jaenisch R. 1976. Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus. Proc Natl Acad Sci USA 73:1260-1264.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 1260-1264
    • Jaenisch, R.1
  • 28
    • 0034696850 scopus 로고    scopus 로고
    • Emx1-specific expression of foreign genes using "knock-in" approach
    • Jin XL, Guo H, Mao C, et al. 2000. Emx1-specific expression of foreign genes using "knock-in" approach. Biochem Biophys Res Commun 270:978-982.
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 978-982
    • Jin, X.L.1    Guo, H.2    Mao, C.3
  • 30
    • 0023090920 scopus 로고
    • A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice
    • Kuehn MR, Bradley A, Robertson EJ, et al. 1987. A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice. Nature 326:295-298.
    • (1987) Nature , vol.326 , pp. 295-298
    • Kuehn, M.R.1    Bradley, A.2    Robertson, E.J.3
  • 31
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander ES, Linton LM, Birren B, et al. 2001. Initial sequencing and analysis of the human genome. Nature 409:860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 32
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • Lee EC, Yu D, Martinez de Velasco J, et al. 2001. A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73:56-65.
    • (2001) Genomics , vol.73 , pp. 56-65
    • Lee, E.C.1    Yu, D.2    De Martinez Velasco, J.3
  • 33
    • 0035826256 scopus 로고    scopus 로고
    • Defining brain wiring patterns and mechanisms through gene trapping in mice
    • Leighton PA, Mitchell KJ, Goodrich LV, et al. 2001. Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature 410:174-179.
    • (2001) Nature , vol.410 , pp. 174-179
    • Leighton, P.A.1    Mitchell, K.J.2    Goodrich, L.V.3
  • 34
    • 0242383276 scopus 로고    scopus 로고
    • Structural and functional maturation of the developing primate brain
    • Levitt P. 2003. Structural and functional maturation of the developing primate brain. Disabil Rehabil 143(4 Suppl):S35-S45.
    • (2003) Disabil Rehabil , vol.143 , Issue.4 SUPPL.
    • Levitt, P.1
  • 35
    • 0035491607 scopus 로고    scopus 로고
    • Conditional control of gene expression in the mouse
    • Lewandoski M. 2001. Conditional control of gene expression in the mouse. Nat Rev Genet 2:743-755.
    • (2001) Nat Rev Genet , vol.2 , pp. 743-755
    • Lewandoski, M.1
  • 36
    • 0346732391 scopus 로고    scopus 로고
    • Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis
    • Li H-S, Wang D, Shen Q, et al. 2003. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron 40:1105-1118.
    • (2003) Neuron , vol.40 , pp. 1105-1118
    • Li, H.-S.1    Wang, D.2    Shen, Q.3
  • 37
    • 3042580701 scopus 로고    scopus 로고
    • Watching the neuromuscular junction
    • Lichtman JW, Sanes JR. 2003. Watching the neuromuscular junction. J Neurocytol 32:767-775.
    • (2003) J Neurocytol , vol.32 , pp. 767-775
    • Lichtman, J.W.1    Sanes, J.R.2
  • 38
    • 0030866899 scopus 로고    scopus 로고
    • Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1
    • Lijam N, Paylor R, McDonald MP, et al. 1997. Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell 90:895-905.
    • (1997) Cell , vol.90 , pp. 895-905
    • Lijam, N.1    Paylor, R.2    McDonald, M.P.3
  • 39
    • 0031916557 scopus 로고    scopus 로고
    • An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination
    • Meyers EN, Lewandoski M, Martin GR. 1998. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat Genet 18:136-141.
    • (1998) Nat Genet , vol.18 , pp. 136-141
    • Meyers, E.N.1    Lewandoski, M.2    Martin, G.R.3
  • 40
    • 0141519291 scopus 로고    scopus 로고
    • A general approach for identifying distant regulatory elements applied to the Gdf6 gene
    • Mortlock DP, Guenther C, Kingsley DM. 2003. A general approach for identifying distant regulatory elements applied to the Gdf6 gene. Genome Res 13:2069-2081.
    • (2003) Genome Res , vol.13 , pp. 2069-2081
    • Mortlock, D.P.1    Guenther, C.2    Kingsley, D.M.3
  • 41
    • 0031924072 scopus 로고    scopus 로고
    • Use of bacteriophage lambda recombination functions to promote gene replacement in Escherichia coli
    • Murphy KC. 1998. Use of bacteriophage lambda recombination functions to promote gene replacement in Escherichia coli. J Bacteriol 180:2063-2071.
    • (1998) J Bacteriol , vol.180 , pp. 2063-2071
    • Murphy, K.C.1
  • 42
    • 0033559118 scopus 로고    scopus 로고
    • Rapid modification of bacterial artificial chromosomes by ET-recombination
    • Muyrers JP, Zhang Y, Testa G, et al. 1999. Rapid modification of bacterial artificial chromosomes by ET-recombination. Nucleic Acids Res 27:1555-1557.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1555-1557
    • Muyrers, J.P.1    Zhang, Y.2    Testa, G.3
  • 43
    • 0034059140 scopus 로고    scopus 로고
    • Cre recombinase: The universal reagent for genome tailoring
    • Nagy A. 2000. Cre recombinase: the universal reagent for genome tailoring. Genesis 26:99-109.
    • (2000) Genesis , vol.26 , pp. 99-109
    • Nagy, A.1
  • 45
    • 0032554783 scopus 로고    scopus 로고
    • Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles
    • Nagy A, Moens C, Ivanyi E, et al. 1998. Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles. Curr Biol 8:661-664.
    • (1998) Curr Biol , vol.8 , pp. 661-664
    • Nagy, A.1    Moens, C.2    Ivanyi, E.3
  • 46
    • 7444231620 scopus 로고    scopus 로고
    • A chromosome 21 critical region does not cause specific Down syndrome phenotypes
    • Olson LE, Richtsmeier JT, Leszl J, Reeves RH. 2004. A chromosome 21 critical region does not cause specific Down syndrome phenotypes. Science 306:687-690.
    • (2004) Science , vol.306 , pp. 687-690
    • Olson, L.E.1    Richtsmeier, J.T.2    Leszl, J.3    Reeves, R.H.4
  • 48
    • 3342938070 scopus 로고    scopus 로고
    • Continuing role for mouse Numb and Numb1 in maintaining progenitor cells during cortical neurogenesis
    • Petersen PH, Zou K, Krauss S, et al. 2004. Continuing role for mouse Numb and Numb1 in maintaining progenitor cells during cortical neurogenesis. Nature Neurosci 7:803-811.
    • (2004) Nature Neurosci , vol.7 , pp. 803-811
    • Petersen, P.H.1    Zou, K.2    Krauss, S.3
  • 49
    • 0035252562 scopus 로고    scopus 로고
    • Too much of a good thing: Mechanisms of gene action in Down syndrome
    • Reeves RH, Baxter LL, Richtsmeier JT. 2001. Too much of a good thing: mechanisms of gene action in Down syndrome. Trends Genet 17:83-88.
    • (2001) Trends Genet , vol.17 , pp. 83-88
    • Reeves, R.H.1    Baxter, L.L.2    Richtsmeier, J.T.3
  • 51
    • 0029023713 scopus 로고
    • Capturing genes encoding membrane and secreted proteins important for mouse development
    • Skarnes WC, Moss JE, Hurtley SM, et al. 1995. Capturing genes encoding membrane and secreted proteins important for mouse development. Proc Natl Acad Sci USA 92:6592-6596.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6592-6596
    • Skarnes, W.C.1    Moss, J.E.2    Hurtley, S.M.3
  • 52
    • 1042291142 scopus 로고    scopus 로고
    • General method for the modification of different BAC types and the rapid generation of BAC transgenic mice
    • Sparwasser T, Gong S, Li JY, et al. 2004. General method for the modification of different BAC types and the rapid generation of BAC transgenic mice. Genesis 38:39-50.
    • (2004) Genesis , vol.38 , pp. 39-50
    • Sparwasser, T.1    Gong, S.2    Li, J.Y.3
  • 53
    • 0035487038 scopus 로고    scopus 로고
    • Genetrap mutagenesis: Past, present and beyond
    • Stanford WL, Cohn JB, Cordes SP. 2001. Genetrap mutagenesis: past, present and beyond. Nat Rev Genet 2:756-768.
    • (2001) Nat Rev Genet , vol.2 , pp. 756-768
    • Stanford, W.L.1    Cohn, J.B.2    Cordes, S.P.3
  • 54
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • Thomas KR, Capecchi MR. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51:503-512.
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 55
    • 0037478651 scopus 로고    scopus 로고
    • Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality
    • Tidcombe H, Jackson-Fisher A, Mathers K, et al. 2003. Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality. Proc Natl Acad Sci USA 100:8281-8286.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8281-8286
    • Tidcombe, H.1    Jackson-Fisher, A.2    Mathers, K.3
  • 57
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter JC, Adams MD, Myers EW, et al. 2001. The sequence of the human genome. Science 291:1304-1351.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 58
    • 0030842624 scopus 로고    scopus 로고
    • Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome
    • Yang XW, Model P, Heintz N. 1997. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nat Biotechnol 15:859-865.
    • (1997) Nat Biotechnol , vol.15 , pp. 859-865
    • Yang, X.W.1    Model, P.2    Heintz, N.3
  • 59
    • 0034705144 scopus 로고    scopus 로고
    • An efficient recombination system for chromosome engineering in Escherichia coli
    • Yu D, Ellis HM, Lee EC, et al. 2000. An efficient recombination system for chromosome engineering in Escherichia coli. Proc Natl Acad Sci USA 97:5978-5983.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5978-5983
    • Yu, D.1    Ellis, H.M.2    Lee, E.C.3
  • 60
    • 0035490099 scopus 로고    scopus 로고
    • Engineering chromosomal rearrangements in mice
    • Yu Y, Bradley A. 2001. Engineering chromosomal rearrangements in mice. Nat Rev Genet 2:780-790.
    • (2001) Nat Rev Genet , vol.2 , pp. 780-790
    • Yu, Y.1    Bradley, A.2
  • 61
    • 0031664853 scopus 로고    scopus 로고
    • A new logic for DNA engineering using recombination in Escherichia coli
    • Zhang Y, Buchholz F, Muyrers JP, et al. 1998. A new logic for DNA engineering using recombination in Escherichia coli. Nat Genet 20:123-128.
    • (1998) Nat Genet , vol.20 , pp. 123-128
    • Zhang, Y.1    Buchholz, F.2    Muyrers, J.P.3


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