메뉴 건너뛰기




Volumn 3, Issue , 2005, Pages

T cell avidity and tumor recognition: Implications and therapeutic strategies

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; EPITOPE; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN RECEPTOR; SIGNAL PEPTIDE; T LYMPHOCYTE RECEPTOR;

EID: 27344449925     PISSN: 14795876     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-3-35     Document Type: Review
Times cited : (25)

References (160)
  • 3
    • 0034722886 scopus 로고    scopus 로고
    • Dendritic cell vaccination for cancer therapy
    • Nestle FO: Dendritic cell vaccination for cancer therapy. Oncogene 2000, 19:6673-6679.
    • (2000) Oncogene , vol.19 , pp. 6673-6679
    • Nestle, F.O.1
  • 4
    • 0033556322 scopus 로고    scopus 로고
    • High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy
    • Zeh HJ, III, Perry-Lalley D, Dudley ME, Rosenberg SA, Yang JC: High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy. JImmunol 1999, 162:989.
    • (1999) J. Immunol. , vol.162 , pp. 989
    • Zeh III, H.J.1    Perry-Lalley, D.2    Dudley, M.E.3    Rosenberg, S.A.4    Yang, J.C.5
  • 11
    • 0031414141 scopus 로고    scopus 로고
    • Human tumour antigens recognized by T cells: New perspectives for anti-cancer vaccines?
    • Coulie PG: Human tumour antigens recognized by T cells: new perspectives for anti-cancer vaccines? MolWedToday 1997, 3:261.
    • (1997) Mol. Med. Today , vol.3 , pp. 261
    • Coulie, P.G.1
  • 12
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • Rosenberg SA: Progress in human tumour immunology and immunotherapy. Nature 2001, 411:380.
    • (2001) Nature , vol.411 , pp. 380
    • Rosenberg, S.A.1
  • 14
    • 0033014974 scopus 로고    scopus 로고
    • Cancer-testis antigens: Targets for cancer immunotherapy
    • [comment] Cancer
    • Chen YT, Old LJ: Cancer-testis antigens: targets for cancer immunotherapy [comment]. Cancer JSciAm 1999, 5:16.
    • (1999) J. Sci. Am. , vol.5 , pp. 16
    • Chen, Y.T.1    Old, L.J.2
  • 16
    • 0342879921 scopus 로고    scopus 로고
    • Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: Characterization of tissue-specific ING1 transcripts and a homologue gene
    • Jager D, Stockert E, Scanlan MJ, Gure AO, Jager E, Knuth A, Old LJ, Chen YT: Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene. Cancer Res 1999, 59:6197.
    • (1999) Cancer Res. , vol.59 , pp. 6197
    • Jager, D.1    Stockert, E.2    Scanlan, M.J.3    Gure, A.O.4    Jager, E.5    Knuth, A.6    Old, L.J.7    Chen, Y.T.8
  • 18
    • 0029085917 scopus 로고
    • A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma
    • Van den EB, Peeters O, De Backer O, Gaugler B, Lucas S, Boon T: A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. JExpMed 1995, 182:689.
    • (1995) J. Exp. Med. , vol.182 , pp. 689
    • Van den, E.B.1    Peeters, O.2    De Backer, O.3    Gaugler, B.4    Lucas, S.5    Boon, T.6
  • 23
    • 0020319636 scopus 로고
    • Epstein-Barr virus-specific cytotoxic T-cell clones restricted through a single HLA antigen
    • Wallace LE, Rickinson AB, Rowe M, Epstein MA: Epstein-Barr virus-specific cytotoxic T-cell clones restricted through a single HLA antigen. Nature 1982, 297:413.
    • (1982) Nature , vol.297 , pp. 413
    • Wallace, L.E.1    Rickinson, A.B.2    Rowe, M.3    Epstein, M.A.4
  • 24
    • 0025169718 scopus 로고
    • An Epstein-Barr virus-specific cytotoxic T cell epitope in EBV nuclear antigen 3 (EBNA 3)
    • Burrows SR, Sculley TB, Misko IS, Schmidt C, Moss DJ: An Epstein-Barr virus-specific cytotoxic T cell epitope in EBV nuclear antigen 3 (EBNA 3). JExpMed 1990, 171:345.
    • (1990) J. Exp. Med. , vol.171 , pp. 345
    • Burrows, S.R.1    Sculley, T.B.2    Misko, I.S.3    Schmidt, C.4    Moss, D.J.5
  • 25
    • 0027424944 scopus 로고
    • Human leukocyte antigen-A2.1 restricted candidate cytotoxic T lymphocyte epitopes of human papillomavirus type 16 E6 and E7 proteins identified by using the processing-defective human cell line T2
    • Kast WM, Brandt RM, Drijfhout JW, Melief CJ: Human leukocyte antigen-A2.1 restricted candidate cytotoxic T lymphocyte epitopes of human papillomavirus type 16 E6 and E7 proteins identified by using the processing-defective human cell line T2. JImmunother 1993, 14:115.
    • (1993) J. Immunother. , vol.14 , pp. 115
    • Kast, W.M.1    Brandt, R.M.2    Drijfhout, J.W.3    Melief, C.J.4
  • 26
    • 0027370248 scopus 로고
    • Cytotoxic T cells isolated from ovarian malignant ascites recognize a peptide derived from the HER-2/neu proto-oncogene
    • Ioannides CG, Fisk B, Fan D, Biddison WE, Wharton JT, O'Brian CA: Cytotoxic T cells isolated from ovarian malignant ascites recognize a peptide derived from the HER-2/neu proto-oncogene. Cell Immunol 1993, 151:225.
    • (1993) Cell Immunol. , vol.151 , pp. 225
    • Ioannides, C.G.1    Fisk, B.2    Fan, D.3    Biddison, W.E.4    Wharton, J.T.5    O'Brian, C.A.6
  • 31
    • 0031905632 scopus 로고    scopus 로고
    • Accumulation of the p53 protein allows recognition by human CTL of a wild-type p53 epitope presented by breast carcinomas and melanomas
    • Gnjatic S, Cai Z, Viguier M, Chouaib S, Guillet JG, Choppin J: Accumulation of the p53 protein allows recognition by human CTL of a wild-type p53 epitope presented by breast carcinomas and melanomas. JImmunol 1998, 160:328.
    • (1998) J. Immunol. , vol.160 , pp. 328
    • Gnjatic, S.1    Cai, Z.2    Viguier, M.3    Chouaib, S.4    Guillet, J.G.5    Choppin, J.6
  • 32
    • 0032520044 scopus 로고    scopus 로고
    • Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes
    • Brossart P, Stuhler G, Flad T, Stevanovic S, Rammensee HG, Kanz L, Brugger W: Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes. Cancer Res 1998, 58:732.
    • (1998) Cancer Res. , vol.58 , pp. 732
    • Brossart, P.1    Stuhler, G.2    Flad, T.3    Stevanovic, S.4    Rammensee, H.G.5    Kanz, L.6    Brugger, W.7
  • 33
    • 0023009267 scopus 로고
    • Identification of a unique tumor antigen as rejection antigen by molecular cloning and gene transfer
    • Stauss HJ, Van Waes C, Fink MA, Starr B, Schreiber H: Identification of a unique tumor antigen as rejection antigen by molecular cloning and gene transfer. J Exp Med 1986, 164:1516-1530.
    • (1986) J. Exp. Med. , vol.164 , pp. 1516-1530
    • Stauss, H.J.1    Van Waes, C.2    Fink, M.A.3    Starr, B.4    Schreiber, H.5
  • 35
    • 0034846053 scopus 로고    scopus 로고
    • Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations
    • Cao K, Hollenbach J, Shi X, Shi W, Chopek M, Fernandez-Vina MA: Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Hum Immunol 2001, 62:1009-1030.
    • (2001) Hum. Immunol. , vol.62 , pp. 1009-1030
    • Cao, K.1    Hollenbach, J.2    Shi, X.3    Shi, W.4    Chopek, M.5    Fernandez-Vina, M.A.6
  • 36
    • 0346244099 scopus 로고    scopus 로고
    • T-cell-antigen recognition and the immunological synapse
    • Huppa JB, Davis MM: T-cell-antigen recognition and the immunological synapse. Nature Reviews Immunology 2003, 3:973.
    • (2003) Nature Reviews Immunology , vol.3 , pp. 973
    • Huppa, J.B.1    Davis, M.M.2
  • 38
    • 0029965055 scopus 로고    scopus 로고
    • Selective expansion of high- or low- avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
    • Alexander-Miller MA, Leggatt GR, Berzofsky JA: Selective expansion of high- or low- avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. ProcNatlAcadSciUSA 1996, 93:4102.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4102
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Berzofsky, J.A.3
  • 39
    • 0029813121 scopus 로고    scopus 로고
    • Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL
    • Alexander-Miller MA, Leggatt GR, Sarin A, Berzofsky JA: Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL. JExpMed 1996, 184:485.
    • (1996) J. Exp. Med. , vol.184 , pp. 485
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Sarin, A.3    Berzofsky, J.A.4
  • 40
    • 0032993029 scopus 로고    scopus 로고
    • Antitumor immunization with a minimal peptide epitope (G9-209-2M) leads to a functionally heterogeneous CTL response
    • Dudley ME, Nishimura MI, Holt AK, Rosenberg SA: Antitumor immunization with a minimal peptide epitope (G9-209-2M) leads to a functionally heterogeneous CTL response. JImmunother 1999, 22:288.
    • (1999) J. Immunother. , vol.22 , pp. 288
    • Dudley, M.E.1    Nishimura, M.I.2    Holt, A.K.3    Rosenberg, S.A.4
  • 41
    • 0041402836 scopus 로고    scopus 로고
    • Epitope-based vaccines: An update on epitope identification, vaccine design and delivery
    • Sette A, Fikes J: Epitope-based vaccines: an update on epitope identification, vaccine design and delivery. Current Opinion in Immunology 2003, 15:461.
    • (2003) Current Opinion in Immunology , vol.15 , pp. 461
    • Sette, A.1    Fikes, J.2
  • 44
    • 0028330866 scopus 로고
    • In vitro generation of human cytolytic T-cells specific for peptides derived from the HER-2/neu protooncogene protein
    • Disis ML, Smith JW, Murphy AE, Chen W, Cheever MA: In vitro generation of human cytolytic T-cells specific for peptides derived from the HER-2/neu protooncogene protein. Cancer Res 1994, 54:1071.
    • (1994) Cancer Res. , vol.54 , pp. 1071
    • Disis, M.L.1    Smith, J.W.2    Murphy, A.E.3    Chen, W.4    Cheever, M.A.5
  • 45
    • 0032213456 scopus 로고    scopus 로고
    • Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptide-specific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors
    • Zaks TZ, Rosenberg SA: Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptide-specific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors. Cancer Res 1998, 58:4902.
    • (1998) Cancer Res. , vol.58 , pp. 4902
    • Zaks, T.Z.1    Rosenberg, S.A.2
  • 46
    • 0036098003 scopus 로고    scopus 로고
    • Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity
    • Knutson KL, Schiffman K, Cheever MA, Disis ML: Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity. ClinCancer Res 2002, 8:1014.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1014
    • Knutson, K.L.1    Schiffman, K.2    Cheever, M.A.3    Disis, M.L.4
  • 49
    • 0034985966 scopus 로고    scopus 로고
    • Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining
    • Derby MA, Wang J, Margulies DH, Berzofsky JA: Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining. IntImmunol 2001, 13:817.
    • (2001) Int. Immunol. , vol.13 , pp. 817
    • Derby, M.A.1    Wang, J.2    Margulies, D.H.3    Berzofsky, J.A.4
  • 50
    • 0036858973 scopus 로고    scopus 로고
    • Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: Crucial role of interaction kinetics on functional outcomes
    • Dutoit V, Guillaume P, Cerottini JC, Romero P, Valmori D: Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes. European Journal of Immunology 2002, 32:3285.
    • (2002) European Journal of Immunology , vol.32 , pp. 3285
    • Dutoit, V.1    Guillaume, P.2    Cerottini, J.C.3    Romero, P.4    Valmori, D.5
  • 51
    • 0035451399 scopus 로고    scopus 로고
    • Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: Correlation with CD8 alpha beta versus CD8 alpha alpha expression
    • Cawthon AG, Lu HP, Alexander-Miller MA: Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: Correlation with CD8 alpha beta versus CD8 alpha alpha expression. Journal of Immunology 2001, 167:2577.
    • (2001) Journal of Immunology , vol.167 , pp. 2577
    • Cawthon, A.G.1    Lu, H.P.2    Alexander-Miller, M.A.3
  • 53
    • 0033941834 scopus 로고    scopus 로고
    • T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes
    • Dudley ME, Ngo LT, Westwood J, Wunderlich JR, Rosenberg SA: T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes. Cancer J 2000, 6:69.
    • (2000) Cancer J. , vol.6 , pp. 69
    • Dudley, M.E.1    Ngo, L.T.2    Westwood, J.3    Wunderlich, J.R.4    Rosenberg, S.A.5
  • 54
    • 0037108364 scopus 로고    scopus 로고
    • Modification of a tumor-derived peptide at an HLA-A2 anchor residue can alter the conformation of the MHC-peptide complex: Probing with TCR-like recombinant antibodies
    • Denkberg G, Klechevsky E, Reiter Y: Modification of a tumor-derived peptide at an HLA-A2 anchor residue can alter the conformation of the MHC-peptide complex: Probing with TCR-like recombinant antibodies. Journal of Immunology 2002, 169:4399.
    • (2002) Journal of Immunology , vol.169 , pp. 4399
    • Denkberg, G.1    Klechevsky, E.2    Reiter, Y.3
  • 55
    • 0028815876 scopus 로고
    • Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen
    • Cole DJ, Weil DP, Shilyansky J, Custer M, Kawakami Y, Rosenberg SA, Nishimura MI: Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen. Cancer Res 1995, 55:748.
    • (1995) Cancer Res. , vol.55 , pp. 748
    • Cole, D.J.1    Weil, D.P.2    Shilyansky, J.3    Custer, M.4    Kawakami, Y.5    Rosenberg, S.A.6    Nishimura, M.I.7
  • 57
    • 0042834246 scopus 로고    scopus 로고
    • High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens
    • Morgan RA, Dudley ME, Yu YYL, Zheng ZL, Robbins PF, Theoret MR, Wunderlich JR, Hughes MS, Restifo NP, Rosenberg SA: High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens. Journal of Immunology 2003, 171:3287.
    • (2003) Journal of Immunology , vol.171 , pp. 3287
    • Morgan, R.A.1    Dudley, M.E.2    Yu, Y.Y.L.3    Zheng, Z.L.4    Robbins, P.F.5    Theoret, M.R.6    Wunderlich, J.R.7    Hughes, M.S.8    Restifo, N.P.9    Rosenberg, S.A.10
  • 59
    • 0029553704 scopus 로고
    • T-cell recognition of antigen. A process controlled by transient intermolecular interactions
    • Boniface JJ, Davis MM: T-cell recognition of antigen. A process controlled by transient intermolecular interactions. AnnNYAcadSci 1995, 766:62.
    • (1995) Ann. N. Y. Acad. Sci. , vol.766 , pp. 62
    • Boniface, J.J.1    Davis, M.M.2
  • 65
    • 0031450369 scopus 로고    scopus 로고
    • Tumor-induced suppression of antitumor reactivity and depression of TCR zeta expression in tumor-draining lymph node lymphocytes: Possible relationship to the Th2 pathway
    • Fu EJ, Arca MJ, Hain JM, Krinock R, Rado J, Cameron MJ, Chang AE, Sondak VK: Tumor-induced suppression of antitumor reactivity and depression of TCR zeta expression in tumor-draining lymph node lymphocytes: Possible relationship to the Th2 pathway. Journal of Immunotherapy 1997, 20:111.
    • (1997) Journal of Immunotherapy , vol.20 , pp. 111
    • Fu, E.J.1    Arca, M.J.2    Hain, J.M.3    Krinock, R.4    Rado, J.5    Cameron, M.J.6    Chang, A.E.7    Sondak, V.K.8
  • 68
    • 0030048536 scopus 로고    scopus 로고
    • Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell- and natural killer cell-mediated cytotoxicity
    • Kono K, Salazar-Onfray F, Petersson M, Hansson J, Masucci G, Wasserman K, Nakazawa T, Anderson P, Kiessling R: Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell- and natural killer cell-mediated cytotoxicity. EurJImmunol 1996, 26:1308.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1308
    • Kono, K.1    Salazar-Onfray, F.2    Petersson, M.3    Hansson, J.4    Masucci, G.5    Wasserman, K.6    Nakazawa, T.7    Anderson, P.8    Kiessling, R.9
  • 72
    • 0024114857 scopus 로고
    • A 2Nd Subunit of Cd8 Is Expressed in Human T-Cells
    • Norment AM, Littman DR: A 2Nd Subunit of Cd8 Is Expressed in Human T-Cells. Embo Journal 1988, 7:3433.
    • (1988) Embo Journal , vol.7 , pp. 3433
    • Norment, A.M.1    Littman, D.R.2
  • 73
    • 0024114542 scopus 로고
    • The Human Lyt-3 Molecule Requires Cd8 for Cell-Surface Expression
    • Disanto JP, Knowles RW, Flomenberg N: The Human Lyt-3 Molecule Requires Cd8 for Cell-Surface Expression. Embo Journal 1988, 7:3465.
    • (1988) Embo Journal , vol.7 , pp. 3465
    • Disanto, J.P.1    Knowles, R.W.2    Flomenberg, N.3
  • 80
    • 0035374117 scopus 로고    scopus 로고
    • On solvability of noncommutative power-associative nilalgebras
    • Correa I, Hentzel IR: On solvability of noncommutative power-associative nilalgebras. Journal of Algebra 2001, 240:98.
    • (2001) Journal of Algebra , vol.240 , pp. 98
    • Correa, I.1    Hentzel, I.R.2
  • 82
    • 0032100538 scopus 로고    scopus 로고
    • Peptides derived from self-proteins as partial agonists and antagonists of human CD8(+) T-cell clones reactive to melanoma/melanocyte epitope MART1(27-35)
    • Loftus DJ, Squarcina P, Nielsen MB, Geisler C, Castelli C, Odum N, Appella E, Parmiani G, Rivoltini L: Peptides derived from self-proteins as partial agonists and antagonists of human CD8(+) T-cell clones reactive to melanoma/melanocyte epitope MART1(27-35). Cancer Research 1998, 58:2433.
    • (1998) Cancer Research , vol.58 , pp. 2433
    • Loftus, D.J.1    Squarcina, P.2    Nielsen, M.B.3    Geisler, C.4    Castelli, C.5    Odum, N.6    Appella, E.7    Parmiani, G.8    Rivoltini, L.9
  • 83
    • 0030587077 scopus 로고    scopus 로고
    • Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues
    • Parkhurst MR, Salgaller ML, Southwood S, Robbins PF, Sette A, Rosenberg SA, Kawakami Y: Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues. JImmunol 1996, 157:2539.
    • (1996) J. Immunol. , vol.157 , pp. 2539
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3    Robbins, P.F.4    Sette, A.5    Rosenberg, S.A.6    Kawakami, Y.7
  • 85
    • 0035138326 scopus 로고    scopus 로고
    • Induction of tumor-reactive cytotoxic T-lymphocytes using a peptide from NY-ESO-1 modified at the carboxy-terminus to enhance HLA-A2.1 binding affinity and stability in solution
    • Bownds S, Tong-On P, Rosenberg SA, Parkhurst M: Induction of tumor-reactive cytotoxic T-lymphocytes using a peptide from NY-ESO-1 modified at the carboxy-terminus to enhance HLA-A2.1 binding affinity and stability in solution. JImmunother 2001, 24:1.
    • (2001) J. Immunother. , vol.24 , pp. 1
    • Bownds, S.1    Tong-On, P.2    Rosenberg, S.A.3    Parkhurst, M.4
  • 89
    • 0031932303 scopus 로고    scopus 로고
    • Human HER-2/neu protein immunization circumvents tolerance to rat neu: A vaccine strategy for 'self' tumour antigens
    • Disis ML, Shiota FM, Cheever MA: Human HER-2/neu protein immunization circumvents tolerance to rat neu: a vaccine strategy for 'self' tumour antigens. Immunology 1998, 93:192.
    • (1998) Immunology , vol.93 , pp. 192
    • Disis, M.L.1    Shiota, F.M.2    Cheever, M.A.3
  • 92
    • 0030882684 scopus 로고    scopus 로고
    • Identification of an enhancer agonist cytotoxic T lymphocyte peptide from human carcinoembryonic antigen
    • Zaremba S, Barzaga E, Zhu MZ, Soares N, Tsang KY, Schlom J: Identification of an enhancer agonist cytotoxic T lymphocyte peptide from human carcinoembryonic antigen. Cancer Research 1997, 57:4570.
    • (1997) Cancer Research , vol.57 , pp. 4570
    • Zaremba, S.1    Barzaga, E.2    Zhu, M.Z.3    Soares, N.4    Tsang, K.Y.5    Schlom, J.6
  • 94
    • 0033555613 scopus 로고    scopus 로고
    • A superagonist variant of peptide MART1/Melan A27-35 elicits anti-melanoma CD8+ T cells with enhanced functional characteristics: Implication for more effective immunotherapy
    • Rivoltini L, Squarcina P, Loftus DJ, Castelli C, Tarsini P, Mazzocchi A, Rini F, Viggiano V, Belli F, Parmiani G: A superagonist variant of peptide MART1/Melan A27-35 elicits anti-melanoma CD8+ T cells with enhanced functional characteristics: implication for more effective immunotherapy. Cancer Res 1999, 59:301.
    • (1999) Cancer Res. , vol.59 , pp. 301
    • Rivoltini, L.1    Squarcina, P.2    Loftus, D.J.3    Castelli, C.4    Tarsini, P.5    Mazzocchi, A.6    Rini, F.7    Viggiano, V.8    Belli, F.9    Parmiani, G.10
  • 96
    • 0035903287 scopus 로고    scopus 로고
    • Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide
    • Tangri S, Ishioka GY, Huang XQ, Sidney J, Southwood S, Fikes S, Sette A: Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide. Journal of Experimental Medicine 2001, 194:833.
    • (2001) Journal of Experimental Medicine , vol.194 , pp. 833
    • Tangri, S.1    Ishioka, G.Y.2    Huang, X.Q.3    Sidney, J.4    Southwood, S.5    Fikes, S.6    Sette, A.7
  • 97
    • 0026598333 scopus 로고
    • Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition
    • Kaye J, Vasquez NJ, Hedrick SM: Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition. JImmunol 1992, 148:3342.
    • (1992) J. Immunol. , vol.148 , pp. 3342
    • Kaye, J.1    Vasquez, N.J.2    Hedrick, S.M.3
  • 98
    • 0025068712 scopus 로고
    • T cell receptor junctional regions and the MHC molecule affect the recognition of antigenic peptides by T cell clones
    • Sorger SB, Paterson Y, Fink PJ, Hedrick SM: T cell receptor junctional regions and the MHC molecule affect the recognition of antigenic peptides by T cell clones. JImmunol 1990, 144:1127.
    • (1990) J. Immunol. , vol.144 , pp. 1127
    • Sorger, S.B.1    Paterson, Y.2    Fink, P.J.3    Hedrick, S.M.4
  • 99
    • 0028826973 scopus 로고
    • Analysis of TCR usage in human tumors: A new tool for assessing tumor-specific immune responses
    • Sensi M, Parmiani G: Analysis of TCR usage in human tumors: a new tool for assessing tumor- specific immune responses. ImmunolToday 1995, 16:588.
    • (1995) Immunol. Today , vol.16 , pp. 588
    • Sensi, M.1    Parmiani, G.2
  • 100
    • 0025044674 scopus 로고
    • Predominant expression of T cell receptor V alpha 7 in tumor-infiltrating lymphocytes of uveal melanoma
    • Nitta T, Oksenberg JR, Rao NA, Steinman L: Predominant expression of T cell receptor V alpha 7 in tumor- infiltrating lymphocytes of uveal melanoma. Science 1990, 249:672.
    • (1990) Science , vol.249 , pp. 672
    • Nitta, T.1    Oksenberg, J.R.2    Rao, N.A.3    Steinman, L.4
  • 101
    • 0027531749 scopus 로고
    • Analysis of T-Cell Receptor Variability in Tumor-Infiltrating Lymphocytes from A Human Regressive Melanoma - Evidence for Insitu T-Cell Clonal Expansion
    • Ferradini L, Mackensen A, Genevee C, Bosq J, Duvillard P, Avril MF, Hercend T: Analysis of T-Cell Receptor Variability in Tumor-Infiltrating Lymphocytes from A Human Regressive Melanoma - Evidence for Insitu T-Cell Clonal Expansion. Journal of Clinical Investigation 1993, 91:1183.
    • (1993) Journal of Clinical Investigation , vol.91 , pp. 1183
    • Ferradini, L.1    Mackensen, A.2    Genevee, C.3    Bosq, J.4    Duvillard, P.5    Avril, M.F.6    Hercend, T.7
  • 102
    • 0028158461 scopus 로고
    • Preferential Usage of T-Cell Receptor-Alpha-Beta Variable Regions Among Tumor-Infiltrating Lymphocytes in Primary Human-Malignant Melanomas
    • Straten PT, Scholler J, Houjensen K, Zeuthen J: Preferential Usage of T-Cell Receptor-Alpha-Beta Variable Regions Among Tumor-Infiltrating Lymphocytes in Primary Human-Malignant Melanomas. International Journal of Cancer 1994, 56:78.
    • (1994) International Journal of Cancer , vol.56 , pp. 78
    • Straten, P.T.1    Scholler, J.2    Houjensen, K.3    Zeuthen, J.4
  • 103
    • 0027496936 scopus 로고
    • Evidence for Oligoclonal T-Cell Response in A Metastasis of Renal-Cell Carcinoma Responding to Vaccination with Autologous Tumor-Cells and Transfer of In-Vitro-Sensitized Vaccine-Draining LymphNode Lymphocytes
    • Weidmann E, Logan TF, Yasumura S, Kirkwood JM, Trucco M, Whiteside TL: Evidence for Oligoclonal T-Cell Response in A Metastasis of Renal-Cell Carcinoma Responding to Vaccination with Autologous Tumor-Cells and Transfer of In-Vitro-Sensitized Vaccine-Draining LymphNode Lymphocytes. Cancer Research 1993, 53:4745.
    • (1993) Cancer Research , vol.53 , pp. 4745
    • Weidmann, E.1    Logan, T.F.2    Yasumura, S.3    Kirkwood, J.M.4    Trucco, M.5    Whiteside, T.L.6
  • 104
    • 0026520851 scopus 로고
    • Dominant Rearrangements Among Human Tumor-Infiltrating Lymphocytes - Analysis of T-Cells Derived from 32 Patients with Melanoma, Lung, and Renal-Cell Carcinoma
    • Bennett WT, Pandolfi F, Grove BH, Hawes GE, Boyle LA, Kradin RL, Kurnick JT: Dominant Rearrangements Among Human Tumor-Infiltrating Lymphocytes - Analysis of T-Cells Derived from 32 Patients with Melanoma, Lung, and Renal-Cell Carcinoma. Cancer 1992, 69:2379.
    • (1992) Cancer , vol.69 , pp. 2379
    • Bennett, W.T.1    Pandolfi, F.2    Grove, B.H.3    Hawes, G.E.4    Boyle, L.A.5    Kradin, R.L.6    Kurnick, J.T.7
  • 105
    • 0027942629 scopus 로고
    • Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope
    • [published erratum appears in Cancer Res 1994 Nov 15;54(22):6014]
    • Cole DJ, Weil DP, Shamamian P, Rivoltini L, Kawakami Y, Topalian S, Jennings C, Eliyahu S, Rosenberg SA, Nishimura MI: Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope [published erratum appears in Cancer Res 1994 Nov 15;54(22):6014]. Cancer Res 1994, 54:5265.
    • (1994) Cancer Res. , vol.54 , pp. 5265
    • Cole, D.J.1    Weil, D.P.2    Shamamian, P.3    Rivoltini, L.4    Kawakami, Y.5    Topalian, S.6    Jennings, C.7    Eliyahu, S.8    Rosenberg, S.A.9    Nishimura, M.I.10
  • 109
    • 0029112509 scopus 로고
    • Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A.1
    • Romero P, Pannetier C, Herman J, Jongeneel CV, Cerottini JC, Coulie PG: Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A.1 JExpMed 1995, 182:1019.
    • (1995) J. Exp. Med. , vol.182 , pp. 1019
    • Romero, P.1    Pannetier, C.2    Herman, J.3    Jongeneel, C.V.4    Cerottini, J.C.5    Coulie, P.G.6
  • 113
    • 0031569521 scopus 로고    scopus 로고
    • Diversity of the cytotoxic melanoma-specific immune response: Some CTL clones recognize autologous fresh tumor cells and not tumor cell lines
    • Dufour E, Carcelain G, Gaudin C, Flament C, Avril MF, Faure F: Diversity of the cytotoxic melanoma-specific immune response: some CTL clones recognize autologous fresh tumor cells and not tumor cell lines. JImmunol 1997, 158:3787.
    • (1997) J. Immunol. , vol.158 , pp. 3787
    • Dufour, E.1    Carcelain, G.2    Gaudin, C.3    Flament, C.4    Avril, M.F.5    Faure, F.6
  • 115
    • 0027199885 scopus 로고
    • T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: Tumor-infiltrating lymphocytes overexpress in vivo the TCR beta chain sequence used by an HLA-A2-restricted and melanocyte-lineage-specific CTL clone
    • Sensi M, Salvi S, Castelli C, Maccalli C, Mazzocchi A, Mortarini R, Nicolini G, Herlyn M, Parmiani G, Anichini A: T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: tumor-infiltrating lymphocytes overexpress in vivo the TCR beta chain sequence used by an HLA-A2- restricted and melanocyte-lineage-specific CTL clone. JExpMed 1993, 178:1231.
    • (1993) J. Exp. Med. , vol.178 , pp. 1231
    • Sensi, M.1    Salvi, S.2    Castelli, C.3    Maccalli, C.4    Mazzocchi, A.5    Mortarini, R.6    Nicolini, G.7    Herlyn, M.8    Parmiani, G.9    Anichini, A.10
  • 116
    • 0029051341 scopus 로고
    • Cytotoxic T-lymphocyte clones from different patients display limited T- cell-receptor variable-region gene usage in HLA-A2-restricted recognition of the melanoma antigen Melan-A/MART-1
    • Sensi M, Traversari C, Radrizzani M, Salvi S, Maccalli C, Mortarini R, Rivoltini L, Farina C, Nicolini G, Wolfel T: Cytotoxic T-lymphocyte clones from different patients display limited T- cell-receptor variable-region gene usage in HLA-A2-restricted recognition of the melanoma antigen Melan-A/MART-1. ProcNatlAcadSciUSA 1995,92:5674.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5674
    • Sensi, M.1    Traversari, C.2    Radrizzani, M.3    Salvi, S.4    Maccalli, C.5    Mortarini, R.6    Rivoltini, L.7    Farina, C.8    Nicolini, G.9    Wolfel, T.10
  • 117
    • 0026502380 scopus 로고
    • Mapping T-Cell Receptor Peptide Contacts by Variant Peptide Immunization of Single-Chain Transgenics
    • Jorgensen JL, Esser U, Destgroth BF, Reay PA, Davis MM: Mapping T-Cell Receptor Peptide Contacts by Variant Peptide Immunization of Single-Chain Transgenics. Nature 1992, 355:224.
    • (1992) Nature , vol.355 , pp. 224
    • Jorgensen, J.L.1    Esser, U.2    Destgroth, B.F.3    Reay, P.A.4    Davis, M.M.5
  • 120
    • 0028302028 scopus 로고
    • Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes
    • Kawakami Y, Eliyahu S, Sakaguchi K, Robbins PF, Rivoltini L, Yannelli JR, Appella E, Rosenberg SA: Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. JExpMed 1994, 180:347.
    • (1994) J. Exp. Med. , vol.180 , pp. 347
    • Kawakami, Y.1    Eliyahu, S.2    Sakaguchi, K.3    Robbins, P.F.4    Rivoltini, L.5    Yannelli, J.R.6    Appella, E.7    Rosenberg, S.A.8
  • 121
    • 0036568413 scopus 로고    scopus 로고
    • TCR reconstitution in Jurkat reporter cells facilitates the identification of novel tumor antigens by cDNA expression cloning
    • Aarnoudse CA, Kruse M, Konopitzky R, Brouwenstijn N, Schrier PI: TCR reconstitution in Jurkat reporter cells facilitates the identification of novel tumor antigens by cDNA expression cloning. IntJCancer 2002, 99:7.
    • (2002) Int. J. Cancer , vol.99 , pp. 7
    • Aarnoudse, C.A.1    Kruse, M.2    Konopitzky, R.3    Brouwenstijn, N.4    Schrier, P.I.5
  • 123
    • 0033168142 scopus 로고    scopus 로고
    • Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity
    • Clay TM, Custer MC, Sachs J, Hwu P, Rosenberg SA, Nishimura MI: Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity. J. Immunol 1999, 163:507-513.
    • (1999) J. Immunol. , vol.163 , pp. 507-513
    • Clay, T.M.1    Custer, M.C.2    Sachs, J.3    Hwu, P.4    Rosenberg, S.A.5    Nishimura, M.I.6
  • 124
    • 0033103155 scopus 로고    scopus 로고
    • Potential use of T cell receptor genes to modify hematopoietic stem cells for the gene therapy of cancer
    • Clay TM, Custer MC, Spiess PJ, Nishimura MI: Potential use of T cell receptor genes to modify hematopoietic stem cells for the gene therapy of cancer. Pathol Oncol Res 1999, 5:3-15.
    • (1999) Pathol. Oncol. Res. , vol.5 , pp. 3-15
    • Clay, T.M.1    Custer, M.C.2    Spiess, P.J.3    Nishimura, M.I.4
  • 125
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller DG, Adam MA, Miller AD: Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. MolCell Biol 1990, 10:4239.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 4239
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 127
    • 0035128975 scopus 로고    scopus 로고
    • Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide
    • Orentas RJ, Roskopf SJ, Nolan GP, Nishimura MI: Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide. ClinImmunol 2001, 98:220.
    • (2001) Clin. Immunol. , vol.98 , pp. 220
    • Orentas, R.J.1    Roskopf, S.J.2    Nolan, G.P.3    Nishimura, M.I.4
  • 128
    • 13944278036 scopus 로고    scopus 로고
    • Simultaneous generation of CD8+ and CD4+ melanoma reactive T cells by retroviral mediated transfer of a single T cell receptor
    • Roszkowski JJ, Eiben GE, Kast WM, Yee C, Van Besien K, Nishimura MI: Simultaneous generation of CD8+ and CD4+ melanoma reactive T cells by retroviral mediated transfer of a single T cell receptor. vol. 65(4); 2005.
    • (2005) , vol.65 , Issue.4
    • Roszkowski, J.J.1    Eiben, G.E.2    Kast, W.M.3    Yee, C.4    Van Besien, K.5    Nishimura, M.I.6
  • 132
    • 18144368144 scopus 로고    scopus 로고
    • Retroviral transduction of peptide stimulated T cells can generate dual T cell receptor-expressing (bifunctional) T cells reactive with two defined antigens
    • Langerman A, Callender GG, Nishimura MI: Retroviral transduction of peptide stimulated T cells can generate dual T cell receptor-expressing (bifunctional) T cells reactive with two defined antigens. JTrans/Med 2004, 2:42.
    • (2004) J. Transl. Med. , vol.2 , pp. 42
    • Langerman, A.1    Callender, G.G.2    Nishimura, M.I.3
  • 133
    • 0029840935 scopus 로고    scopus 로고
    • Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor
    • Blichfeldt E, Munthe LA, Rotnes JS, Bogen B: Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor. EurfImmunol 1996, 26:2876.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2876
    • Blichfeldt, E.1    Munthe, L.A.2    Rotnes, J.S.3    Bogen, B.4
  • 134
    • 0030585533 scopus 로고    scopus 로고
    • T cells with two Tcrbeta chains and reactivity to both MHC/idiotypic peptide and superantigen
    • Munthe LA, Blichfeldt E, Sollien A, Dembic Z, Bogen B: T cells with two Terbeta chains and reactivity to both MHC/idiotypic peptide and superantigen. Cell Immunol 1996, 170:283.
    • (1996) Cell. Immunol. , vol.170 , pp. 283
    • Munthe, L.A.1    Blichfeldt, E.2    Sollien, A.3    Dembic, Z.4    Bogen, B.5
  • 136
    • 0034764497 scopus 로고    scopus 로고
    • Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites
    • Vagner S, Galy B, Pyronnet S: Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites. EMBO Rep 2001, 2:893.
    • (2001) EMBO Rep. , vol.2 , pp. 893
    • Vagner, S.1    Galy, B.2    Pyronnet, S.3
  • 137
    • 0037481021 scopus 로고    scopus 로고
    • Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence
    • Cavalieri S, Cazzaniga S, Geuna M, Magnani Z, Bordignon C, Naldini L, Bonini C: Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence. Blood 2003, 102:497-505.
    • (2003) Blood , vol.102 , pp. 497-505
    • Cavalieri, S.1    Cazzaniga, S.2    Geuna, M.3    Magnani, Z.4    Bordignon, C.5    Naldini, L.6    Bonini, C.7
  • 139
    • 0036529821 scopus 로고    scopus 로고
    • Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide
    • Maurice M, Verhoeyen E, Salmon P, Trono D, Russell SJ, Cosset FL: Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide. Blood 2002, 99:2342.
    • (2002) Blood , vol.99 , pp. 2342
    • Maurice, M.1    Verhoeyen, E.2    Salmon, P.3    Trono, D.4    Russell, S.J.5    Cosset, F.L.6
  • 141
    • 0024834988 scopus 로고
    • Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity
    • Gross G, Waks T, Eshhar Z: Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity. Proc Natl Acad Sci USA 1989, 86:10024-10028.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 10024-10028
    • Gross, G.1    Waks, T.2    Eshhar, Z.3
  • 142
    • 0027501259 scopus 로고
    • Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors
    • Stancovski I, Schindler DG, Waks T, Yarden Y, Sela M, Eshhar Z: Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors. J Immunol 1993, 151:6577-6582.
    • (1993) J. Immunol. , vol.151 , pp. 6577-6582
    • Stancovski, I.1    Schindler, D.G.2    Waks, T.3    Yarden, Y.4    Sela, M.5    Eshhar, Z.6
  • 143
    • 0033974799 scopus 로고    scopus 로고
    • Ligand-mediated cytolysis of tumor cells: Use of heregulin-zeta chimeras to redirect cytotoxic T lymphocytes
    • Muniappan A, Banapour B, Lebkowski J, Talib S: Ligand-mediated cytolysis of tumor cells: use of heregulin-zeta chimeras to redirect cytotoxic T lymphocytes. Cancer Gene Ther 2000, 7:128-134.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 128-134
    • Muniappan, A.1    Banapour, B.2    Lebkowski, J.3    Talib, S.4
  • 144
    • 0031306874 scopus 로고    scopus 로고
    • Adoptive transfer of in vitro-targeted, activated T lymphocytes results in total tumor regression
    • Altenschmidt U, Klundt E, Groner B: Adoptive transfer of in vitro-targeted, activated T lymphocytes results in total tumor regression. J Immunol 1997, 159:5509-5515.
    • (1997) J. Immunol. , vol.159 , pp. 5509-5515
    • Altenschmidt, U.1    Klundt, E.2    Groner, B.3
  • 146
  • 148
    • 0030014521 scopus 로고    scopus 로고
    • Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity
    • Weijtens ME, Willemsen RA, Valerio D, Stam K, Bolhuis RL: Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity. J Immunol 1996, 157:836-843.
    • (1996) J. Immunol. , vol.157 , pp. 836-843
    • Weijtens, M.E.1    Willemsen, R.A.2    Valerio, D.3    Stam, K.4    Bolhuis, R.L.5
  • 149
    • 0034526330 scopus 로고    scopus 로고
    • Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors
    • Yun CO, Nolan KF, Beecham EJ, Reisfeld RA, Junghans RP: Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors. Neoplasia 2000, 2:449-459.
    • (2000) Neoplasia , vol.2 , pp. 449-459
    • Yun, C.O.1    Nolan, K.F.2    Beecham, E.J.3    Reisfeld, R.A.4    Junghans, R.P.5
  • 150
    • 0034038324 scopus 로고    scopus 로고
    • Redirected cellular cytotoxicity by infection of effector cells with a recombinant vaccinia virus encoding a tumor-specific monoclonal antibody
    • Paul S, Bizouarne N, Dott K, Ruet L, Dufour P, Acres RB, Kieny MP: Redirected cellular cytotoxicity by infection of effector cells with a recombinant vaccinia virus encoding a tumor-specific monoclonal antibody. Cancer Gene Ther 2000, 7:615-623.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 615-623
    • Paul, S.1    Bizouarne, N.2    Dott, K.3    Ruet, L.4    Dufour, P.5    Acres, R.B.6    Kieny, M.P.7
  • 152
    • 0031946483 scopus 로고    scopus 로고
    • Expression in cytotoxic T lymphocytes of a single-chain anti-carcinoembryonic antigen antibody. Redirected Fas ligand-mediated lysis of colon carcinoma
    • Darcy PK, Kershaw MH, Trapani JA, Smyth MJ: Expression in cytotoxic T lymphocytes of a single-chain anti-carcinoembryonic antigen antibody. Redirected Fas ligand-mediated lysis of colon carcinoma. Eur J Immunol 1998, 28:1663-1672.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1663-1672
    • Darcy, P.K.1    Kershaw, M.H.2    Trapani, J.A.3    Smyth, M.J.4
  • 153
    • 0033385052 scopus 로고    scopus 로고
    • Bypassing immunization: Optimized design of "designer T cells" against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA
    • Nolan KF, Yun CO, Akamatsu Y, Murphy JC, Leung SO, Beecham EJ, Junghans RP: Bypassing immunization: optimized design of "designer T cells" against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA. Clin Cancer Res 1999, 5:3928-3941.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3928-3941
    • Nolan, K.F.1    Yun, C.O.2    Akamatsu, Y.3    Murphy, J.C.4    Leung, S.O.5    Beecham, E.J.6    Junghans, R.P.7
  • 154
    • 0036221688 scopus 로고    scopus 로고
    • Human natural killer cell line modified with a chimeric immunoglobulin T-cell receptor gene leads to tumor growth inhibition in vivo
    • Schirrmann T, Pecher G: Human natural killer cell line modified with a chimeric immunoglobulin T-cell receptor gene leads to tumor growth inhibition in vivo. Cancer Gene Ther 2002, 9:390-398.
    • (2002) Cancer Gene Ther. , vol.9 , pp. 390-398
    • Schirrmann, T.1    Pecher, G.2
  • 155
    • 0035159470 scopus 로고    scopus 로고
    • Redirecting mouse CTL against colon carcinoma: Superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma
    • Haynes NM, Snook MB, Trapani JA, Cerruti L, Jane SM, Smyth MJ, Darcy PK: Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma. J Immunol 2001, 166:182-187.
    • (2001) J. Immunol. , vol.166 , pp. 182-187
    • Haynes, N.M.1    Snook, M.B.2    Trapani, J.A.3    Cerruti, L.4    Jane, S.M.5    Smyth, M.J.6    Darcy, P.K.7
  • 156
    • 0036137615 scopus 로고    scopus 로고
    • Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor
    • Maher J, Brentjens RJ, Gunset G, Riviere I, Sadelain M: Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor. Nat Biotechnol 2002, 20:70-75.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 70-75
    • Maher, J.1    Brentjens, R.J.2    Gunset, G.3    Riviere, I.4    Sadelain, M.5
  • 158
    • 0032531091 scopus 로고    scopus 로고
    • Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product
    • Finney HM, Lawson AD, Bebbington CR, Weir AN: Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product. J Immunol 1998, 161:2791-2797.
    • (1998) J. Immunol. , vol.161 , pp. 2791-2797
    • Finney, H.M.1    Lawson, A.D.2    Bebbington, C.R.3    Weir, A.N.4
  • 159
    • 0035576250 scopus 로고    scopus 로고
    • Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule
    • Hombach A, Wieczarkowiecz A, Marquardt T, Heuser C, Usai L, Pohl C, Seliger B, Abken H: Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule. J Immunol 2001, 167:6123-6131.
    • (2001) J. Immunol. , vol.167 , pp. 6123-6131
    • Hombach, A.1    Wieczarkowiecz, A.2    Marquardt, T.3    Heuser, C.4    Usai, L.5    Pohl, C.6    Seliger, B.7    Abken, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.