Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ/CD28 receptor

Nature Biotechnology

Volumn 20, Issue 1, 2002, Pages 70-75

  Maher, John ^a   Brentjens, Renier J ^a   Gunset, Gertrude ^a   Rivière, Isabelle ^a   Sadelain, Michel ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CELLS; IMMUNOLOGY; TUMORS;

CYTOLYTIC ACTIVITIES;

BIOTECHNOLOGY;

CD28 ANTIGEN; CHIMERIC PROTEIN; INTERLEUKIN 2; PROSTATE SPECIFIC MEMBRANE ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG;

ADOPTIVE IMMUNOTHERAPY; ANTIGEN SPECIFICITY; ARTICLE; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOLYSIS; DNA MODIFICATION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TUMOR IMMUNITY;

ANTIGENS, CD28; CELL DIVISION; CELLS, CULTURED; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; HUMANS; INTERLEUKIN-2; MEMBRANE PROTEINS; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS; TRANSDUCTION, GENETIC;

RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0036137615     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0102-70     Document Type: Article

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