Bypassing immunization: Optimized design of 'designer T cells' against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA

Clinical Cancer Research

Volumn 5, Issue 12, 1999, Pages 3928-3941

  Nolan, K F ^a   Yun, C O ^a   Akamatsu, Y ^a   Murphy, J C ^a   Leung, S O ^b   Beecham, E J ^a   Junghans, R P ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Immunomedics   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; IMMUNOGLOBULIN; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

ANTIGEN BINDING; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CANCER IMMUNIZATION; CANCER IMMUNOTHERAPY; CELL ACTIVATION; CELL INTERACTION; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TARGET CELL;

ANTIGENS, CD3; CARCINOEMBRYONIC ANTIGEN; COLONIC NEOPLASMS; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNOGLOBULINS; IMMUNOTHERAPY, ADOPTIVE; INTERLEUKIN-2; JURKAT CELLS; LYMPHOCYTE ACTIVATION; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SOLUBILITY; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER; TUMOR CELLS, CULTURED;

EID: 0033385052     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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