-
1
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW et al. The sequence of the human genome. Science 291, 1304-1351 (2001).
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
-
2
-
-
7444260846
-
-
The ENCODE (ENCyclopedia Of DNA Elements) Project
-
ENCODE Project Consortium. The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 306, 636-640 (2004).
-
(2004)
Science
, vol.306
, pp. 636-640
-
-
-
3
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 431, 931-945 (2004).
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
4
-
-
4444227630
-
Genomic approaches that aid in the identification of transcription factor target genes
-
Kirmizis A, Farnham PJ. Genomic approaches that aid in the identification of transcription factor target genes. Exp. Biol. Med. (Maywood) 229, 705-721 (2004). Provides examples of how both expression arrays and chromatin immunoprecipitation-chip microarray-based assays can be used to identify target genes.
-
(2004)
Exp. Biol. Med. (Maywood)
, vol.229
, pp. 705-721
-
-
Kirmizis, A.1
Farnham, P.J.2
-
5
-
-
0003392343
-
-
Cold Spring Harbor Laboratory Press, NY, USA
-
Carey M, Smale ST. Transcriptional Regulation in Eukaryotes: Concepts, Strategies, and Techniques. Cold Spring Harbor Laboratory Press, NY, USA, 640 (1999). Provides a comprehensive overview of most of the techniques available for the study of transcription regulation, and identifies pros and cons of each particular technique.
-
(1999)
Transcriptional Regulation in Eukaryotes: Concepts, Strategies, and Techniques
, pp. 640
-
-
Carey, M.1
Smale, S.T.2
-
6
-
-
0023124097
-
Firefly luciferase gene: Structure and expression in mammalian cells
-
de Wet JR, Wood KV, DeLuca M, Helinski DR, Subramani S. Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell Biol. 7, 725-737 (1987).
-
(1987)
Mol. Cell Biol.
, vol.7
, pp. 725-737
-
-
De Wet, J.R.1
Wood, K.V.2
DeLuca, M.3
Helinski, D.R.4
Subramani, S.5
-
7
-
-
0023084134
-
Use of eukaryotic expression technology in the functional analysis of cloned genes
-
Cullen BR. Use of eukaryotic expression technology in the functional analysis of cloned genes. Methods Enzymol. 152, 684-704 (1987).
-
(1987)
Methods Enzymol.
, vol.152
, pp. 684-704
-
-
Cullen, B.R.1
-
8
-
-
0030872393
-
Multiple control elements mediate activation of the murine and human interleukin-12 p40 promoters: Evidence of functional synergy between C/EBP and Rel proteins
-
Plevy SE, Gemberling JH, Hsu S, Dorner AJ, Smale ST. Multiple control elements mediate activation of the murine and human interleukin-12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins. Mol. Cell Biol. 17, 4572-4588 (1997). One of the best examples of the use of deletion analysis and reporter gene expression in the identification of cis-acting elements.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 4572-4588
-
-
Plevy, S.E.1
Gemberling, J.H.2
Hsu, S.3
Dorner, A.J.4
Smale, S.T.5
-
9
-
-
0018199224
-
DNAse footprinting: A simple method for the detection of protein-DNA binding specificity
-
Galas DJ, Schmitz A. DNAse footprinting: a simple method for the detection of protein-DNA binding specificity. Nucleic Acids Res. 5, 3157-3170 (1978).
-
(1978)
Nucleic Acids Res.
, vol.5
, pp. 3157-3170
-
-
Galas, D.J.1
Schmitz, A.2
-
11
-
-
0028446567
-
DNA recognition by DNase I
-
Suck D. DNA recognition by DNase I. J. Mol. Recognit. 7, 65-70 (1994).
-
(1994)
J. Mol. Recognit.
, vol.7
, pp. 65-70
-
-
Suck, D.1
-
12
-
-
0018816003
-
Exonuclease III of Escherichia colt K-12, an AP endonuclease
-
Rogers SG, Weiss B. Exonuclease III of Escherichia colt K-12, an AP endonuclease. Methods Enzymol. 65, 201-211 (1980).
-
(1980)
Methods Enzymol.
, vol.65
, pp. 201-211
-
-
Rogers, S.G.1
Weiss, B.2
-
13
-
-
0018867360
-
E. coli RNA polymerase interacts homologously with two different promoters
-
Siebenlist U, Simpson RB, Gilbert W. E. coli RNA polymerase interacts homologously with two different promoters. Cell 20, 269-281 (1980).
-
(1980)
Cell
, vol.20
, pp. 269-281
-
-
Siebenlist, U.1
Simpson, R.B.2
Gilbert, W.3
-
14
-
-
0018874853
-
Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion
-
Shalloway D, Kleinberger T, Livingston DM. Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion. Cell 20, 411-422 (1980).
-
(1980)
Cell
, vol.20
, pp. 411-422
-
-
Shalloway, D.1
Kleinberger, T.2
Livingston, D.M.3
-
15
-
-
0035227217
-
Footprinting with exonuclease III
-
Metzger W, Heumann H. Footprinting with exonuclease III. Methods Mol. Biol. 148, 39-47 (2001).
-
(2001)
Methods Mol. Biol.
, vol.148
, pp. 39-47
-
-
Metzger, W.1
Heumann, H.2
-
16
-
-
0024453869
-
An amino-terminal fragment of GAL4 binds DNA as a dimer
-
Carey M, Kakidani H, Leatherwood J, Mostashari F, Ptashne M. An amino-terminal fragment of GAL4 binds DNA as a dimer. J. Mol. Biol. 209, 423-432 (1989).
-
(1989)
J. Mol. Biol.
, vol.209
, pp. 423-432
-
-
Carey, M.1
Kakidani, H.2
Leatherwood, J.3
Mostashari, F.4
Ptashne, M.5
-
17
-
-
0023623752
-
Hydroxyl radical footprinting: A high-resolution method for mapping protein-DNA contacts
-
Tullius TD, Dombroski BA, Churchill ME, Kam L. Hydroxyl radical footprinting: a high-resolution method for mapping protein-DNA contacts. Methods Enzymol. 155, 537-558 (1987).
-
(1987)
Methods Enzymol.
, vol.155
, pp. 537-558
-
-
Tullius, T.D.1
Dombroski, B.A.2
Churchill, M.E.3
Kam, L.4
-
18
-
-
0035222715
-
Hydroxyl radical footprinting
-
Zaychikov E, Schickor P, Denissova L, Heumann H. Hydroxyl radical footprinting. Methods Mol. Biol. 148, 49-61 (2001).
-
(2001)
Methods Mol. Biol.
, vol.148
, pp. 49-61
-
-
Zaychikov, E.1
Schickor, P.2
Denissova, L.3
Heumann, H.4
-
19
-
-
0023032496
-
Mapping of the sites of protection on a 5 S RNA gene by the Xenopus transcription Factor IIIA. A model for the interaction
-
Fairall L, Rhodes D, Klug A. Mapping of the sites of protection on a 5 S RNA gene by the Xenopus transcription Factor IIIA. A model for the interaction. J. Mol. Biol. 192, 577-591 (1986).
-
(1986)
J. Mol. Biol.
, vol.192
, pp. 577-591
-
-
Fairall, L.1
Rhodes, D.2
Klug, A.3
-
20
-
-
0035235824
-
Identification of protein-DNA contacts with dimethyl sulfate. Methylation protection and methylation interference
-
Shaw PE, Stewart AF. Identification of protein-DNA contacts with dimethyl sulfate. Methylation protection and methylation interference. Methods Mol. Biol. 148, 221-227 (2001).
-
(2001)
Methods Mol. Biol.
, vol.148
, pp. 221-227
-
-
Shaw, P.E.1
Stewart, A.F.2
-
21
-
-
0025884915
-
Probing the nature of chromosomal DNA-protein contacts by in vivo footprinting
-
196 passim
-
Cartwright IL, Kelly SE. Probing the nature of chromosomal DNA-protein contacts by in vivo footprinting. Biotechniques 11, 188-190, 192-184, 196 passim (1991).
-
(1991)
Biotechniques
, vol.11
, pp. 188-190
-
-
Cartwright, I.L.1
Kelly, S.E.2
-
23
-
-
12844281113
-
Characterization of the survival motor neurone (SMN) promoter provides evidence for complex combinatorial regulation in undifferentiated and differentiated p19 cells
-
Rouget R, Vigneault F, Codio C et al. Characterization of the survival motor neurone (SMN) promoter provides evidence for complex combinatorial regulation in undifferentiated and differentiated p19 cells. Biochem. J. 385, 433-443 (2005).
-
(2005)
Biochem. J.
, vol.385
, pp. 433-443
-
-
Rouget, R.1
Vigneault, F.2
Codio, C.3
-
24
-
-
20844435623
-
High-throughput localization of functional elements by quantitative chromatin profiling
-
Dorschner MO, Hawrylycz M, Humbert R et al. High-throughput localization of functional elements by quantitative chromatin profiling. Nature Methods 1, 219-225 (2004).
-
(2004)
Nature Methods
, vol.1
, pp. 219-225
-
-
Dorschner, M.O.1
Hawrylycz, M.2
Humbert, R.3
-
25
-
-
4444364399
-
Bioinformatics for the 'bench biologist': How to find regulatory regions in genomic DNA
-
Nardone J, Lee DU, Ansel KM, Rao A. Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA. Nature Immunol. 5, 768-774 (2004).
-
(2004)
Nature Immunol.
, vol.5
, pp. 768-774
-
-
Nardone, J.1
Lee, D.U.2
Ansel, K.M.3
Rao, A.4
-
26
-
-
0034072450
-
DNA binding sites: Representation and discovery
-
Stormo GD. DNA binding sites: representation and discovery. Bioinformatics 16, 16-23 (2000).
-
(2000)
Bioinformatics
, vol.16
, pp. 16-23
-
-
Stormo, G.D.1
-
27
-
-
20844436318
-
Identifying regulatory subnetworks for a set of genes
-
Scott MS, Perkins T, Bunnell S, Pepin F, Thomas DY, Hallett MT. Identifying regulatory subnetworks for a set of genes. Mol. Cell. Proteomics 4(5), 683-692 (2005).
-
(2005)
Mol. Cell. Proteomics
, vol.4
, Issue.5
, pp. 683-692
-
-
Scott, M.S.1
Perkins, T.2
Bunnell, S.3
Pepin, F.4
Thomas, D.Y.5
Hallett, M.T.6
-
28
-
-
13444270902
-
The MAPPER database: A multi-genome catalog of putative transcription factor binding sites
-
Marinescu VD, Kohane IS, Riva A. The MAPPER database: a multi-genome catalog of putative transcription factor binding sites. Nucleic Acids Res. 33(Database issue), D91-D97 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
, Issue.DATABASE ISSUE
-
-
Marinescu, V.D.1
Kohane, I.S.2
Riva, A.3
-
29
-
-
3242891274
-
ConSite: Web-based prediction of regulatory elements using cross-species comparison
-
Sandelin A, Wasserman WW, Lenhard B. ConSite: web-based prediction of regulatory elements using cross-species comparison. Nucleic Acids Res. 32, W249-W252 (2004).
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Sandelin, A.1
Wasserman, W.W.2
Lenhard, B.3
-
30
-
-
1842584947
-
Applied bioinformatics for the identification of regulatory elements
-
Wasserman WW, Sandelin A. Applied bioinformatics for the identification of regulatory elements. Nature Rev. Genet. 5, 276-287 (2004). Describes recent advances in the field of bioinformatics toward identification of transcription factor binding sites.
-
(2004)
Nature Rev. Genet.
, vol.5
, pp. 276-287
-
-
Wasserman, W.W.1
Sandelin, A.2
-
31
-
-
0347125328
-
JASPAR: An open-access database for eukaryotic transcription factor binding profiles
-
Sandelin A, Alkema W, Engstrom P, Wasserman WW, Lenhard B. JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res. 32, D91-D94 (2004).
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Sandelin, A.1
Alkema, W.2
Engstrom, P.3
Wasserman, W.W.4
Lenhard, B.5
-
32
-
-
0041829442
-
Recent advances in computational promoter analysis in understanding the transcriptional regulatory network
-
Qiu P. Recent advances in computational promoter analysis in understanding the transcriptional regulatory network. Biochem. Biophys. Res. Commun. 309, 495-501 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.309
, pp. 495-501
-
-
Qiu, P.1
-
33
-
-
0024323026
-
Measurement of protein-DNA interaction parameters by electrophoresis mobility shift assay
-
Fried MG. Measurement of protein-DNA interaction parameters by electrophoresis mobility shift assay. Electrophoresis 10, 366-376 (1989).
-
(1989)
Electrophoresis
, vol.10
, pp. 366-376
-
-
Fried, M.G.1
-
35
-
-
0031834942
-
Electrophoretic analysis of multiple protein-DNA interactions
-
Fried MG, Daugheny MA. Electrophoretic analysis of multiple protein-DNA interactions. Electrophoresis 19, 1247-1253 (1998).
-
(1998)
Electrophoresis
, vol.19
, pp. 1247-1253
-
-
Fried, M.G.1
Daugheny, M.A.2
-
36
-
-
0031016591
-
Factors that affect the stability of protein-DNA complexes during gel electrophoresis
-
Fried MG, Bromberg JL. Factors that affect the stability of protein-DNA complexes during gel electrophoresis. Electrophoresis 18, 6-11 (1997).
-
(1997)
Electrophoresis
, vol.18
, pp. 6-11
-
-
Fried, M.G.1
Bromberg, J.L.2
-
37
-
-
0033989991
-
Electrophoretic mobility shift assays
-
Molloy PL. Electrophoretic mobility shift assays. Methods Mol. Biol. 130, 235-246 (2000).
-
(2000)
Methods Mol. Biol.
, vol.130
, pp. 235-246
-
-
Molloy, P.L.1
-
38
-
-
0035223264
-
Electrophoretic mobility shift assays for the analysis of DNA-protein interactions
-
Laniel MA, Beliveau A, Guerin SL. Electrophoretic mobility shift assays for the analysis of DNA-protein interactions. Methods Mol. Biol. 148, 13-30 (2001).
-
(2001)
Methods Mol. Biol.
, vol.148
, pp. 13-30
-
-
Laniel, M.A.1
Beliveau, A.2
Guerin, S.L.3
-
39
-
-
0032503693
-
The gut-enriched Kruppel-like factor suppresses the activity of the CYPlAl promoter in an Sp1-dependent fashion
-
Zhang W, Shields JM, Sogawa K, Fujii-Kuriyama Y, Yang VW. The gut-enriched Kruppel-like factor suppresses the activity of the CYPlAl promoter in an Sp1-dependent fashion. J. Biol. Chem. 273, 17917-17925 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17917-17925
-
-
Zhang, W.1
Shields, J.M.2
Sogawa, K.3
Fujii-Kuriyama, Y.4
Yang, V.W.5
-
40
-
-
0031039923
-
Transforming growth factor-α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation
-
Gille J, Swerlick RA, Caughman SW. Transforming growth factor-α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation. EMBO J. 16, 750-759 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 750-759
-
-
Gille, J.1
Swerlick, R.A.2
Caughman, S.W.3
-
41
-
-
0030050712
-
Identification, purification, and molecular cloning of autonomously replicating sequence-binding protein 1 from fission yeast Schizosaccharomyces pombe
-
Murakami Y, Huberman JA, Hurwitz J. Identification, purification, and molecular cloning of autonomously replicating sequence-binding protein 1 from fission yeast Schizosaccharomyces pombe. Proc. Natl Acad. Sci. USA 93, 502-507 (1996).
-
(1996)
Proc. Natl. Sci. USA
, vol.93
, pp. 502-507
-
-
Murakami, Y.1
Huberman, J.A.2
Hurwitz, J.3
-
42
-
-
2642703473
-
DNA-binding activities of Hop 1 protein, a synaptonemal complex component from Saccharomyces cerevisiae
-
Kironmai KM, Muniyappa K, Friedman DB, Hollingsworth NM, Byers B. DNA-binding activities of Hop 1 protein, a synaptonemal complex component from Saccharomyces cerevisiae. Mol. Cell Biol. 18, 1424-1435 (1998).
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 1424-1435
-
-
Kironmai, K.M.1
Muniyappa, K.2
Friedman, D.B.3
Hollingsworth, N.M.4
Byers, B.5
-
43
-
-
0031298187
-
A nuclear factor orner dian Sp1 binds the GC-rich promoter of the gene encoding rat poly(ADP-ribose) polymerase in vitro
-
Laniel MA, Bergeron MJ, Poirier GG, Guerin SL. A nuclear factor orner dian Sp1 binds the GC-rich promoter of the gene encoding rat poly(ADP-ribose) polymerase in vitro. Biochem. Cell Biol. 75, 427-434 (1997).
-
(1997)
Biochem. Cell Biol.
, vol.75
, pp. 427-434
-
-
Laniel, M.A.1
Bergeron, M.J.2
Poirier, G.G.3
Guerin, S.L.4
-
44
-
-
3042582472
-
Expression of die α4 integrin subunit gene promoter is modulated by the transcription factor Pax-6 in corneal epithelial cells
-
Zaniolo K, Ledere S, Cvekl A et al. Expression of die α4 integrin subunit gene promoter is modulated by the transcription factor Pax-6 in corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 45, 1692-1704 (2004).
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 1692-1704
-
-
Zaniolo, K.1
Ledere, S.2
Cvekl, A.3
-
45
-
-
0023768292
-
Specific protein-DNA complexes: Immunodetection of the protein component after gel electrophoresis and western blotting
-
Granger-Schnarr M, Lloubes R, de Murcia G, Schnarr M. Specific protein-DNA complexes: immunodetection of the protein component after gel electrophoresis and western blotting. Anal. Biochem. 174, 235-238 (1988).
-
(1988)
Anal. Biochem.
, vol.174
, pp. 235-238
-
-
Granger-Schnarr, M.1
Lloubes, R.2
De Murcia, G.3
Schnarr, M.4
-
46
-
-
0027476430
-
Identification and analysis of all components of a gel retardation assay by combination with immunoblotting
-
Demczuk S, Harbers M, Vennstrom B. Identification and analysis of all components of a gel retardation assay by combination with immunoblotting. Proc. Natl Acad. Sci. USA 90, 2574-2578 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2574-2578
-
-
Demczuk, S.1
Harbers, M.2
Vennstrom, B.3
-
47
-
-
0029118240
-
Immunodepletion EMSA: A novel method to identify proteins in a protein-DNA complex
-
Dyer RB, Herzog NK. Immunodepletion EMSA: a novel method to identify proteins in a protein-DNA complex. Nucleic Adds Res. 23, 3345-3346 (1995).
-
(1995)
Nucleic Adds Res.
, vol.23
, pp. 3345-3346
-
-
Dyer, R.B.1
Herzog, N.K.2
-
48
-
-
0035827537
-
Nuclear factor 1 interferes with Sp1 binding through a composite element on the rat poly(ADP-ribose) polymerase promoter to modulate its activity in vitro
-
Laniel MA, Poirier GG, Guerin SL. Nuclear factor 1 interferes with Sp1 binding through a composite element on the rat poly(ADP-ribose) polymerase promoter to modulate its activity in vitro. J. Biol. Chem. 276, 20766-20773 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20766-20773
-
-
Laniel, M.A.1
Poirier, G.G.2
Guerin, S.L.3
-
49
-
-
0027192267
-
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
-
Braunstein M, Rose AB, Holmes SG, Allis CD, Broach JR. Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev. 7, 592-604 (1993).
-
(1993)
Genes Dev.
, vol.7
, pp. 592-604
-
-
Braunstein, M.1
Rose, A.B.2
Holmes, S.G.3
Allis, C.D.4
Broach, J.R.5
-
50
-
-
0031027431
-
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
-
Strahl-Bolsinger S, Hecht A, Luo K, Grunstein M. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11, 83-93 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 83-93
-
-
Strahl-Bolsinger, S.1
Hecht, A.2
Luo, K.3
Grunstein, M.4
-
51
-
-
0030949835
-
Myc versus USF: Discrimination at the cad gene is determined by core promoter elements
-
Boyd KE, Farnham PJ. Myc versus USF: discrimination at the cad gene is determined by core promoter elements. Mol. Cell Biol. 17, 2529-2537 (1997).
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 2529-2537
-
-
Boyd, K.E.1
Farnham, P.J.2
-
52
-
-
0032506243
-
c-Myc target gene specificity is determined by a post-DNA binding mechanism
-
Boyd KE, Wells J, Gutman J, Bardey SM, Farnham PJ. c-Myc target gene specificity is determined by a post-DNA binding mechanism. Proc. Natl Acad. Sci. USA 95, 13887-13892 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13887-13892
-
-
Boyd, K.E.1
Wells, J.2
Gutman, J.3
Bardey, S.M.4
Farnham, P.J.5
-
53
-
-
3843114956
-
Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation
-
Im H, Grass JA, Johnson KD, Boyer ME, Wu J, Bresnick EH. Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation. Methods Mol. Biol. 284, 129-146 (2004).
-
(2004)
Methods Mol. Biol.
, vol.284
, pp. 129-146
-
-
Im, H.1
Grass, J.A.2
Johnson, K.D.3
Boyer, M.E.4
Wu, J.5
Bresnick, E.H.6
-
54
-
-
0036024954
-
Dissecting long-range transcriptional mechanisms by chromatin immunoprecipitation
-
Johnson KD, Bresnick EH. Dissecting long-range transcriptional mechanisms by chromatin immunoprecipitation. Methods 26, 27-36 (2002).
-
(2002)
Methods
, vol.26
, pp. 27-36
-
-
Johnson, K.D.1
Bresnick, E.H.2
-
55
-
-
4644262823
-
Characterization of protein-DNA association in vivo by chromatin immunoprecipitation
-
Kuras L. Characterization of protein-DNA association in vivo by chromatin immunoprecipitation. Methods Mol. Biol. 284, 147-162 (2004).
-
(2004)
Methods Mol. Biol.
, vol.284
, pp. 147-162
-
-
Kuras, L.1
-
56
-
-
0032015647
-
Virus infection induces the assembly of co-ordinately activated transcription factors on the IFN-β enhancer in vivo
-
Wathelet MG, Lin CH, Parekh BS, Ronco LV, Howley PM, Maniatis T. Virus infection induces the assembly of co-ordinately activated transcription factors on the IFN-β enhancer in vivo. Mol. Cell 1, 507-518 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 507-518
-
-
Wathelet, M.G.1
Lin, C.H.2
Parekh, B.S.3
Ronco, L.V.4
Howley, P.M.5
Maniatis, T.6
-
57
-
-
0034854577
-
Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter
-
Johnson KD, Christensen HM, Zhao B, Bresnick EH. Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter. Mol. Cell 8, 465-471 (2001).
-
(2001)
Mol. Cell
, vol.8
, pp. 465-471
-
-
Johnson, K.D.1
Christensen, H.M.2
Zhao, B.3
Bresnick, E.H.4
-
58
-
-
0001473216
-
Formaldehyde-mediated DNA-protein crosslinking: A probe for in vivo chromatin structures
-
Solomon MJ, Varshavsky A. Formaldehyde-mediated DNA-protein crosslinking: a probe for in vivo chromatin structures. Proc. Natl Acad. Sci. USA 82, 6470-6474 (1985).
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 6470-6474
-
-
Solomon, M.J.1
Varshavsky, A.2
-
59
-
-
0036024957
-
Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation
-
Wells J, Farnham PJ. Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods 26, 48-56 (2002). Detailed description of multiple applications of chromatin immunoprecipitation toward transcription factor characterization.
-
(2002)
Methods
, vol.26
, pp. 48-56
-
-
Wells, J.1
Farnham, P.J.2
-
60
-
-
0032550174
-
The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops
-
de Belle I, Cai S, Kohwi-Shigematsu T. The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops. J Cell Biol. 141, 335-348 (1998).
-
(1998)
J. Cell Biol.
, vol.141
, pp. 335-348
-
-
De Belle, I.1
Cai, S.2
Kohwi-Shigematsu, T.3
-
61
-
-
0031972490
-
Identification of base-unpairing region-binding proteins and characterization of their in vivo binding sequences
-
Kohwi-Shigematsu T, deBeile I, Dickinson LA, Galande S, Kohwi Y. Identification of base-unpairing region-binding proteins and characterization of their in vivo binding sequences. Methods Cell Biol. 53, 323-354 (1998).
-
(1998)
Methods Cell Biol.
, vol.53
, pp. 323-354
-
-
Kohwi-Shigematsu, T.1
DeBeile, I.2
Dickinson, L.A.3
Galande, S.4
Kohwi, Y.5
-
62
-
-
0034802618
-
Use of chromatin immunoprecipitation to done novel E2F target promoters
-
Weinmann AS, Hartley SM, Zhang T, Zhang MQ, Farnham PJ. Use of chromatin immunoprecipitation to done novel E2F target promoters. Mol. Cell Biol. 21, 6820-6832 (2001).
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 6820-6832
-
-
Weinmann, A.S.1
Hartley, S.M.2
Zhang, T.3
Zhang, M.Q.4
Farnham, P.J.5
-
63
-
-
0036024955
-
Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation
-
Weinmann AS, Farnham PJ. Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods 26, 37-47 (2002).
-
(2002)
Methods
, vol.26
, pp. 37-47
-
-
Weinmann, A.S.1
Farnham, P.J.2
-
64
-
-
0026108692
-
Light-directed, spatially addressable parallel chemical synthesis
-
Fodor SP, Read JL, Pirrung MC, Stryer L, Lu AT, Solas D. Light-directed, spatially addressable parallel chemical synthesis. Science 251, 767-773 (1991).
-
(1991)
Science
, vol.251
, pp. 767-773
-
-
Fodor, S.P.1
Read, J.L.2
Pirrung, M.C.3
Stryer, L.4
Lu, A.T.5
Solas, D.6
-
65
-
-
0034704248
-
Genome-wide location and function of DNA binding proteins
-
Ren B, Robert F, Wyrick JJ et al. Genome-wide location and function of DNA binding proteins. Science 290, 2306-2309 (2000).
-
(2000)
Science
, vol.290
, pp. 2306-2309
-
-
Ren, B.1
Robert, F.2
Wyrick, J.J.3
-
66
-
-
0034934774
-
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association
-
Lieb JD, Liu X, Botstein D, Brown PO. Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nature Genet. 28, 327-334 (2001).
-
(2001)
Nature Genet.
, vol.28
, pp. 327-334
-
-
Lieb, J.D.1
Liu, X.2
Botstein, D.3
Brown, P.O.4
-
67
-
-
0035945567
-
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF
-
Iyer VR, Horak CE, Scafe CS, Botstein D, Snyder M, Brown PO. Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF. Nature 409, 533-538 (2001).
-
(2001)
Nature
, vol.409
, pp. 533-538
-
-
Iyer, V.R.1
Horak, C.E.2
Scafe, C.S.3
Botstein, D.4
Snyder, M.5
Brown, P.O.6
-
68
-
-
8844285956
-
Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress
-
Hayakawa J, Mittal S, Wang Y et al. Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress. Mol. Cell 16, 521-535(2004).
-
(2004)
Mol. Cell
, vol.16
, pp. 521-535
-
-
Hayakawa, J.1
Mittal, S.2
Wang, Y.3
-
69
-
-
0038492517
-
A global transcriptional regulatory role for c-Myc in Burkitt s lymphoma cells
-
Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, Ren B. A global transcriptional regulatory role for c-Myc in Burkitt s lymphoma cells. Proc. Natl Acad. Sci. USA 100, 8164-8169 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8164-8169
-
-
Li, Z.1
Van Calcar, S.2
Qu, C.3
Cavenee, W.K.4
Zhang, M.Q.5
Ren, B.6
-
70
-
-
10744227070
-
Control of pancreas and liver gene expression by HNF transcription factors
-
Odom DT, Zizlsperger N, Gordon DB et al. Control of pancreas and liver gene expression by HNF transcription factors. Science 303, 1378-1381 (2004).
-
(2004)
Science
, vol.303
, pp. 1378-1381
-
-
Odom, D.T.1
Zizlsperger, N.2
Gordon, D.B.3
-
71
-
-
0037080674
-
Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis
-
Weinmann AS, Yan PS, Oberley MJ, Huang TH, Farnham PJ. Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes Dev. 16, 235-244 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 235-244
-
-
Weinmann, A.S.1
Yan, P.S.2
Oberley, M.J.3
Huang, T.H.4
Farnham, P.J.5
-
72
-
-
10044271961
-
GC/AT-content spikes as genomic punctuation marks
-
Zhang L, Kasif S, Cantor CR, Broude NE. GC/AT-content spikes as genomic punctuation marks. Proc. Natl Acad. Sci. USA 101, 16855-16860 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16855-16860
-
-
Zhang, L.1
Kasif, S.2
Cantor, C.R.3
Broude, N.E.4
-
73
-
-
0033822364
-
Large-scale human promoter mapping using CpG islands
-
Ioshikhes IP, Zhang MQ. Large-scale human promoter mapping using CpG islands. Nature Genet. 26, 61-63 (2000).
-
(2000)
Nature Genet.
, vol.26
, pp. 61-63
-
-
Ioshikhes, I.P.1
Zhang, M.Q.2
-
74
-
-
0035236049
-
Promoter prediction in the human genome
-
Hannenhalli S, Levy S. Promoter prediction in the human genome. Bioinformatics 17(Suppl. 1), S90-S96 (2001).
-
(2001)
Bioinformatics
, vol.17
, Issue.SUPPL. 1
-
-
Hannenhalli, S.1
Levy, S.2
-
75
-
-
9644268153
-
Rapid analysis of the DNA-binding specificities of transcription factors with DNA microarrays
-
Mukherjee S, Berger MF, Jona G et al. Rapid analysis of the DNA-binding specificities of transcription factors with DNA microarrays. Nature Genet. 36, 1331-1339 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 1331-1339
-
-
Mukherjee, S.1
Berger, M.F.2
Jona, G.3
-
77
-
-
0142027777
-
Distribution of NF-κB-binding sites across human chromosome 22
-
Martone R, Euskirchen G, Bertone P et al. Distribution of NF-κB-binding sites across human chromosome 22. Proc. Natl Acad. Sci. USA 100, 12247-12252 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12247-12252
-
-
Martone, R.1
Euskirchen, G.2
Bertone, P.3
-
78
-
-
10744226888
-
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs
-
Cawley S, Bekiranov S, Ng HH et al. Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell 116, 499-509 (2004).
-
(2004)
Cell
, vol.116
, pp. 499-509
-
-
Cawley, S.1
Bekiranov, S.2
Ng, H.H.3
-
79
-
-
18744380399
-
Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment
-
Kim J, Bhinge AA, Morgan XC, Iyer VR. Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment. Nature Methods 2, 47-53 (2004). Interesting new technology is described in detail with possible development for the years to come.
-
(2004)
Nature Methods
, vol.2
, pp. 47-53
-
-
Kim, J.1
Bhinge, A.A.2
Morgan, X.C.3
Iyer, V.R.4
-
80
-
-
0024503338
-
Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene
-
Rastinejad F, Polverini PJ, Bouck NP. Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene. Cell 56, 345-355 (1989).
-
(1989)
Cell
, vol.56
, pp. 345-355
-
-
Rastinejad, F.1
Polverini, P.J.2
Bouck, N.P.3
-
81
-
-
0037277722
-
Vascular endothelial cell growth factor (VEGF), an emerging target for cancer chemotherapy
-
Shinkaruk S, Bayle M, Lain G, Deleris G. Vascular endothelial cell growth factor (VEGF), an emerging target for cancer chemotherapy. Curr. Med. Chem. 3, 95-117 (2003).
-
(2003)
Curr. Med. Chem.
, vol.3
, pp. 95-117
-
-
Shinkaruk, S.1
Bayle, M.2
Lain, G.3
Deleris, G.4
-
82
-
-
19944428379
-
Androgens repress the expression of the angiogenesis inhibitor thrombospondin-1 in normal and neoplastic prostate
-
Colombel M, Pilleur S, Fournier P et al. Androgens repress the expression of the angiogenesis inhibitor thrombospondin-1 in normal and neoplastic prostate. Cancer Res. 65, 300-308 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 300-308
-
-
Colombel, M.1
Pilleur, S.2
Fournier, P.3
-
83
-
-
0042173218
-
siRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to anti-angiogenic thrombospondin-1 and slows tumor vascularization and growth
-
Pilleur S, Courtin A, Ait-Si-Ali S et al. siRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to anti-angiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res. 63, 3919-3922 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 3919-3922
-
-
Pilleur, S.1
Courtin, A.2
Ait-Si-Ali, S.3
-
84
-
-
0033529565
-
Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
-
Kornberg RD, Lorch Y. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome. Cell 98, 285-294 (1999).
-
(1999)
Cell
, vol.98
, pp. 285-294
-
-
Kornberg, R.D.1
Lorch, Y.2
-
85
-
-
14544293651
-
Structural basis of eukaryotic gene transcription
-
Boeger H, Bushnell DA, Davis Ret al. Structural basis of eukaryotic gene transcription. FEBS Lett. 579, 899-903 (2005).
-
(2005)
FEBS Lett.
, vol.579
, pp. 899-903
-
-
Boeger, H.1
Bushnell, D.A.2
Davis, R.3
-
86
-
-
0034387004
-
25 Years after the nucleosome model: Chromatin modifications
-
Wu J, Grunstein M. 25 years after the nucleosome model: chromatin modifications. Trends Biochem. Sci. 25, 619-623 (2000).
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 619-623
-
-
Wu, J.1
Grunstein, M.2
-
88
-
-
0034328925
-
Gene therapy: Trials and tribulations
-
Somia N, Verma IM. Gene therapy: trials and tribulations. Nature Rev. Genet. 1, 91-99 (2000).
-
(2000)
Nature Rev. Genet.
, vol.1
, pp. 91-99
-
-
Somia, N.1
Verma, I.M.2
-
89
-
-
0030928619
-
Gene therapy - Promises, problems and prospects
-
Verma IM, Somia N. Gene therapy - promises, problems and prospects. Nature 389, 239-242 (1997).
-
(1997)
Nature
, vol.389
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
90
-
-
0032580354
-
Drug delivery and targeting
-
Langer R. Drug delivery and targeting. Nature 392, 5-10 (1998).
-
(1998)
Nature
, vol.392
, pp. 5-10
-
-
Langer, R.1
-
91
-
-
0038387390
-
The dawning era of polymer therapeutics
-
Duncan R. The dawning era of polymer therapeutics. Nature Rev. Drug Discov. 2, 347-360 (2003).
-
(2003)
Nature Rev. Drug Discov.
, vol.2
, pp. 347-360
-
-
Duncan, R.1
-
92
-
-
14644439267
-
Cancer nanotechnology: Opportunities and challenges
-
Ferrari M. Cancer nanotechnology: opportunities and challenges. Nature Rev. Cancer 5, 161-171 (2005).
-
(2005)
Nature Rev. Cancer
, vol.5
, pp. 161-171
-
-
Ferrari, M.1
-
93
-
-
0037184446
-
Designing macromolecules for therapeutic applications: Polyester dendrimer-poly(ethylene oxide) 'bow-tie' hybrids with tunable molecular weight and architecture
-
Gillies ER, Frechet JM. Designing macromolecules for therapeutic applications: polyester dendrimer-poly(ethylene oxide) 'bow-tie' hybrids with tunable molecular weight and architecture. J. Am. Chem. Soc. 124, 14137-14146 (2002).
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 14137-14146
-
-
Gillies, E.R.1
Frechet, J.M.2
-
94
-
-
0033980297
-
Doxorubicin-loaded poly(ethylene glycol)-poly(β-benzyl-L-aspartate) co-polymer micelles: Their pharmaceutical characteristics and biological significance
-
Kataoka K, Matsumoto T, Yokoyama M et al. Doxorubicin-loaded poly(ethylene glycol)-poly(β-benzyl-L-aspartate) co-polymer micelles: their pharmaceutical characteristics and biological significance. J. Control Release 64, 143-153 (2000).
-
(2000)
J. Control Release
, vol.64
, pp. 143-153
-
-
Kataoka, K.1
Matsumoto, T.2
Yokoyama, M.3
-
95
-
-
0032552819
-
Detection of functional groups and antibodies on microfabricated surfaces by confocal microscopy
-
Nashat AH, Moronne M, Ferrari M. Detection of functional groups and antibodies on microfabricated surfaces by confocal microscopy. Biotechnol. Bioeng. 60, 137-146 (1998).
-
(1998)
Biotechnol. Bioeng.
, vol.60
, pp. 137-146
-
-
Nashat, A.H.1
Moronne, M.2
Ferrari, M.3
-
96
-
-
0142062528
-
Microfabrication of silicon-based nanoporous participates for medical applications
-
Cohen MH, Melnik K, Boiasrki A, Ferrari M, Martin FJ. Microfabrication of silicon-based nanoporous participates for medical applications. Biomed. Microdevices 5, 253-259 (2003).
-
(2003)
Biomed. Microdevices
, vol.5
, pp. 253-259
-
-
Cohen, M.H.1
Melnik, K.2
Boiasrki, A.3
Ferrari, M.4
Martin, F.J.5
-
97
-
-
0038451393
-
Bioconjugated nanoparticles for DNA protection from cleavage
-
He XX, Wang K, Tan W et al. Bioconjugated nanoparticles for DNA protection from cleavage. J. Am. Chem. Soc. 125, 7168-7169 (2003).
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 7168-7169
-
-
He, X.X.1
Wang, K.2
Tan, W.3
-
98
-
-
0347761656
-
The embedding of meta-tetra(hydroxyphenyl)-chlorin into silica nanoparticle platforms for photodynamic therapy and their singlet oxygen production and pH-dependent optical properties
-
Yan F, Kopelman R. The embedding of meta-tetra(hydroxyphenyl)-chlorin into silica nanoparticle platforms for photodynamic therapy and their singlet oxygen production and pH-dependent optical properties. Photochem. Photobiol. 78, 587-591 (2003).
-
(2003)
Photochem. Photobiol.
, vol.78
, pp. 587-591
-
-
Yan, F.1
Kopelman, R.2
-
99
-
-
0000057760
-
Porosified silicon wafer structures impregnated with platinum antitumor compounds: Fabrication, characterization, and diffusion studies
-
Li X, St John J, Coffer JL et al. Porosified silicon wafer structures impregnated with platinum antitumor compounds: fabrication, characterization, and diffusion studies. Biomed. Microdevices 2, 265-273 (2000).
-
(2000)
Biomed. Microdevices
, vol.2
, pp. 265-273
-
-
Li, X.1
St. John, J.2
Coffer, J.L.3
-
100
-
-
0000559725
-
Polymeric systems for controlled drug release
-
Uhrich KE, Cannizzaro SM, Langer RS, Shakesheff KM. Polymeric systems for controlled drug release. Chem. Rev. 99, 3181-3198 (1999).
-
(1999)
Chem. Rev.
, vol.99
, pp. 3181-3198
-
-
Uhrich, K.E.1
Cannizzaro, S.M.2
Langer, R.S.3
Shakesheff, K.M.4
-
101
-
-
1842856911
-
Biodegradable polymeric nanospheres formed by temperature-induced phase transition in a mixture of poly(lactide-co-glycolide) and poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock co-polymer
-
Lee KE, Kim BK, Yuk SH. Biodegradable polymeric nanospheres formed by temperature-induced phase transition in a mixture of poly(lactide-co-glycolide) and poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock co-polymer. Biomacromolecules 3, 1115-1119 (2002).
-
(2002)
Biomacromolecules
, vol.3
, pp. 1115-1119
-
-
Lee, K.E.1
Kim, B.K.2
Yuk, S.H.3
-
102
-
-
1342301607
-
Nanoshell-enabled photonics-based imaging and therapy of cancer
-
Loo C, Lin A, Hirsch L et al. Nanoshell-enabled photonics-based imaging and therapy of cancer. Technol. Cancer Res. 3, 33-40 (2004).
-
(2004)
Technol. Cancer Res.
, vol.3
, pp. 33-40
-
-
Loo, C.1
Lin, A.2
Hirsch, L.3
-
103
-
-
0345686712
-
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
-
Hirsch LR, Stafford RJ, Bankson JA et al. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc. Natl Acad. Sci. USA 100, 13549-13554 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13549-13554
-
-
Hirsch, L.R.1
Stafford, R.J.2
Bankson, J.A.3
-
104
-
-
0038290677
-
A whole blood immunoassay using gold nanoshells
-
Hirsch LR, Jackson JB, Lee A, Halas NJ, West JL. A whole blood immunoassay using gold nanoshells. Anal. Chem. 75, 2377-2381 (2003).
-
(2003)
Anal. Chem.
, vol.75
, pp. 2377-2381
-
-
Hirsch, L.R.1
Jackson, J.B.2
Lee, A.3
Halas, N.J.4
West, J.L.5
-
105
-
-
0037200020
-
Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection
-
Cao YC, Jin R, Mirkin CA. Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection. Science 297, 1536-1540 (2002).
-
(2002)
Science
, vol.297
, pp. 1536-1540
-
-
Cao, Y.C.1
Jin, R.2
Mirkin, C.A.3
-
106
-
-
0037036108
-
Direct patterning of modified oligonucleotides on metals and insulators by dip-pen nanolithography
-
Demers LM, Ginger DS, Park SJ, Li Z, Chung SW, Mirkin CA. Direct patterning of modified oligonucleotides on metals and insulators by dip-pen nanolithography. Science 296, 1836-1838 (2002).
-
(2002)
Science
, vol.296
, pp. 1836-1838
-
-
Demers, L.M.1
Ginger, D.S.2
Park, S.J.3
Li, Z.4
Chung, S.W.5
Mirkin, C.A.6
-
107
-
-
0037154825
-
Array-based electrical detection of DNA with nanoparticle probes
-
Park SJ, Taton TA, Mirkin CA. Array-based electrical detection of DNA with nanoparticle probes. Science 295, 1503-1506 (2002).
-
(2002)
Science
, vol.295
, pp. 1503-1506
-
-
Park, S.J.1
Taton, T.A.2
Mirkin, C.A.3
-
108
-
-
0036096806
-
Liposome-based drug delivery in breast cancer treatment
-
Park JW. Liposome-based drug delivery in breast cancer treatment. Breast Cancer Res. 4, 95-99 (2002).
-
(2002)
Breast Cancer Res.
, vol.4
, pp. 95-99
-
-
Park, J.W.1
-
109
-
-
0034965972
-
Procedures for microencapsulation of enzymes, cells and genetically engineered microorganisms
-
Chang TM, Prakash S. Procedures for microencapsulation of enzymes, cells and genetically engineered microorganisms. Mol. Biotechnol. 17, 249-260 (2001).
-
(2001)
Mol. Biotechnol.
, vol.17
, pp. 249-260
-
-
Chang, T.M.1
Prakash, S.2
-
110
-
-
0033652054
-
A nonviral DNA delivery system based on surface modified silica-nanoparticles can efficiently transfect cells in vitro
-
Kneuer C, Sameti M, Bakowsky U et al. A nonviral DNA delivery system based on surface modified silica-nanoparticles can efficiently transfect cells in vitro. Bioconjug. Chem. 11, 926-932 (2000).
-
(2000)
Bioconjug. Chem.
, vol.11
, pp. 926-932
-
-
Kneuer, C.1
Sameti, M.2
Bakowsky, U.3
-
111
-
-
0031036238
-
Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes
-
Radler JO, Koltover I, Salditt T, Safinya CR. Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 275, 810-814 (1997).
-
(1997)
Science
, vol.275
, pp. 810-814
-
-
Radler, J.O.1
Koltover, I.2
Salditt, T.3
Safinya, C.R.4
-
112
-
-
0032479572
-
An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery
-
Koltover I, Salditt T, Radler JO, Safinya CR. An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Science 281, 78-81 (1998).
-
(1998)
Science
, vol.281
, pp. 78-81
-
-
Koltover, I.1
Salditt, T.2
Radler, J.O.3
Safinya, C.R.4
-
113
-
-
2442575025
-
Bio-bar-code-based DNA detection with PCR-like sensitivity
-
Nam JM, Stoeva SI, Mirkin CA. Bio-bar-code-based DNA detection with PCR-like sensitivity. J. Am. Chem. Soc. 126, 5932-5933 (2004).
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 5932-5933
-
-
Nam, J.M.1
Stoeva, S.I.2
Mirkin, C.A.3
-
114
-
-
0034006169
-
TAT peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
-
Lewin M, Carlesso N, Tung CH et al. TAT peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nature Biotechnol. 18, 410-414 (2000).
-
(2000)
Nature Biotechnol.
, vol.18
, pp. 410-414
-
-
Lewin, M.1
Carlesso, N.2
Tung, C.H.3
-
115
-
-
0032819838
-
Anticancer activity of targeted pro-apoptotic peptides
-
Ellerby HM, Arap W, Ellerby LM et al. Anticancer activity of targeted pro-apoptotic peptides. Nature Med. 5, 1032-1038 (1999).
-
(1999)
Nature Med.
, vol.5
, pp. 1032-1038
-
-
Ellerby, H.M.1
Arap, W.2
Ellerby, L.M.3
-
116
-
-
0037022366
-
Targeting the prostate for destruction through a vascular address
-
Arap W, Haedicke W, Bernasconi M et al. Targeting the prostate for destruction through a vascular address. Proc. Natl Acad. Sci. USA 99, 1527-1531 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1527-1531
-
-
Arap, W.1
Haedicke, W.2
Bernasconi, M.3
-
117
-
-
0036499986
-
Protein nanoarrays generated by dip-pen nanolithography
-
Lee KB, Park SJ, Mirkin CA, Smith JC, Mrksich M. Protein nanoarrays generated by dip-pen nanolithography. Science 295, 1702-1705 (2002).
-
(2002)
Science
, vol.295
, pp. 1702-1705
-
-
Lee, K.B.1
Park, S.J.2
Mirkin, C.A.3
Smith, J.C.4
Mrksich, M.5
-
118
-
-
0038075523
-
Protein nanostructures formed via direct-write dip-pen nanolithography
-
Lee KB, Lim JH, Mirkin CA. Protein nanostructures formed via direct-write dip-pen nanolithography. J. Am. Chem. Soc. 125, 5588-5589 (2003).
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 5588-5589
-
-
Lee, K.B.1
Lim, J.H.2
Mirkin, C.A.3
-
119
-
-
2542599146
-
An addressable antibody nanoarray produced on a nanostructured surface
-
Bruckbauer A, Zhou D, Kang DJ, Korchev YE, Abell C, Klenerman D. An addressable antibody nanoarray produced on a nanostructured surface. J. Am. Chem. Soc. 126, 6508-6509 (2004).
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 6508-6509
-
-
Bruckbauer, A.1
Zhou, D.2
Kang, D.J.3
Korchev, Y.E.4
Abell, C.5
Klenerman, D.6
-
120
-
-
1542375855
-
Microelectronic DNA assay for the detection of BRCA1 gene mutations
-
Chen H, Han J, Li J, Meyyappan M. Microelectronic DNA assay for the detection of BRCA1 gene mutations. Biomed. Microdevices 6, 55-60 (2004).
-
(2004)
Biomed. Microdevices
, vol.6
, pp. 55-60
-
-
Chen, H.1
Han, J.2
Li, J.3
Meyyappan, M.4
-
121
-
-
0035298847
-
Cantilever-based optical deflection assay for discrimination of DNA single-nucleotide mismatches
-
Hansen KM, Ji HF, Wu G et al. Cantilever-based optical deflection assay for discrimination of DNA single-nucleotide mismatches. Anal. Chem. 73, 1567-1571 (2001).
-
(2001)
Anal. Chem.
, vol.73
, pp. 1567-1571
-
-
Hansen, K.M.1
Ji, H.F.2
Wu, G.3
-
122
-
-
0036921523
-
Bioassays based on molecular nanomechanics
-
Majumdar A. Bioassays based on molecular nanomechanics. Dis. Markers 18, 167-174 (2002).
-
(2002)
Dis. Markers
, vol.18
, pp. 167-174
-
-
Majumdar, A.1
-
123
-
-
0034874270
-
Bioassay of prostate-specific antigen (PSA) using microcantilevers
-
Wu G, Datar RH, Hansen KM, Thundat T, Cote RJ, Majumdar A. Bioassay of prostate-specific antigen (PSA) using microcantilevers. Nature Biotechnol. 19, 856-860 (2001).
-
(2001)
Nature Biotechnol.
, vol.19
, pp. 856-860
-
-
Wu, G.1
Datar, R.H.2
Hansen, K.M.3
Thundat, T.4
Cote, R.J.5
Majumdar, A.6
-
124
-
-
0028670569
-
In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
-
Choo Y, Sanchez-Garcia I, Klug A. In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence. Nature 372, 642-645 (1994).
-
(1994)
Nature
, vol.372
, pp. 642-645
-
-
Choo, Y.1
Sanchez-Garcia, I.2
Klug, A.3
-
125
-
-
0040215628
-
Repetitive zinc-binding domains in the protein transcription Factor IIIA from Xenopus oocytes
-
Miller J, McLachlan AD, Klug A. Repetitive zinc-binding domains in the protein transcription Factor IIIA from Xenopus oocytes. EMBO J. 4, 1609-1614 (1985).
-
(1985)
EMBO J.
, vol.4
, pp. 1609-1614
-
-
Miller, J.1
McLachlan, A.D.2
Klug, A.3
-
126
-
-
14544301097
-
Towards therapeutic applications of engineered zinc finger proteins
-
Klug A. Towards therapeutic applications of engineered zinc finger proteins. FEBS Lett. 579, 892-894 (2005). Describes in detail recent advances in the field of protein engineering, and discusses ongoing experiments.
-
(2005)
FEBS Lett.
, vol.579
, pp. 892-894
-
-
Klug, A.1
-
127
-
-
0036912846
-
Induction of angiogenesis in a mouse model using engineered transcription factors
-
Rebar EJ, Huang Y, Hickey R et al. Induction of angiogenesis in a mouse model using engineered transcription factors. Nature Med. 8, 1427-1432 (2002).
-
(2002)
Nature Med.
, vol.8
, pp. 1427-1432
-
-
Rebar, E.J.1
Huang, Y.2
Hickey, R.3
-
128
-
-
0035815697
-
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A
-
Liu PQ, Rebar EJ, Zhang L et al. Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J. Biol. Chem. 276, 11323-11334 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11323-11334
-
-
Liu, P.Q.1
Rebar, E.J.2
Zhang, L.3
-
129
-
-
0028040520
-
Molecular basis for three X-linked immune disorders
-
Puck JM. Molecular basis for three X-linked immune disorders. Hum. Mol. Genet. 3, 1457-1461 (1994).
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1457-1461
-
-
Puck, J.M.1
-
132
-
-
0038523969
-
Chimeric nucleases stimulate gene targeting in human cells
-
Porteus MH, Baltimore D. Chimeric nucleases stimulate gene targeting in human cells. Science 300, 763 (2003).
-
(2003)
Science
, vol.300
, pp. 763
-
-
Porteus, M.H.1
Baltimore, D.2
-
133
-
-
0037510038
-
Enhancing gene targeting with designed zinc finger nucleases
-
Bibikova M, Beumer K, Trautman JK, Carroll D. Enhancing gene targeting with designed zinc finger nucleases. Science 300, 764 (2003).
-
(2003)
Science
, vol.300
, pp. 764
-
-
Bibikova, M.1
Beumer, K.2
Trautman, J.K.3
Carroll, D.4
|