메뉴 건너뛰기




Volumn 17, Issue 8, 1997, Pages 4572-4588

Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: Evidence of functional synergy between C/EBP and Rel proteins

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DEOXYRIBONUCLEASE I; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; PROTEIN P40; PROTEIN RE1; UNCLASSIFIED DRUG;

EID: 0030872393     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.8.4572     Document Type: Article
Times cited : (275)

References (66)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787-793.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 3
    • 0029920849 scopus 로고    scopus 로고
    • Evidence for posttranscriptional regulation of C/EBPα and C/EBPβ isoform expression during the lipopolysaccharide-mediated acute-phase response
    • An, M. R., C.-C. Hsieh, P. D. Reisner, J. P. Rabek, S. G. Scott, D. T. Kuninger, and J. Papaconstantinou. 1996. Evidence for posttranscriptional regulation of C/EBPα and C/EBPβ isoform expression during the lipopolysaccharide-mediated acute-phase response. Mol. Cell. Biol. 16:2295-2306.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2295-2306
    • An, M.R.1    Hsieh, C.-C.2    Reisner, P.D.3    Rabek, J.P.4    Scott, S.G.5    Kuninger, D.T.6    Papaconstantinou, J.7
  • 4
    • 0027331583 scopus 로고
    • The role of NF-κB and NF-IL6 transactivating factors in the synergistic activation of human serum amyloid a gene expression by interleukin-1 and interleukin-6
    • Betts, J. C., J. K. Cheshire, S. Akira, T. Kishimoto, and P. Woo. 1993. The role of NF-κB and NF-IL6 transactivating factors in the synergistic activation of human serum amyloid A gene expression by interleukin-1 and interleukin-6. J. Biol. Chem. 268:25624-25631.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25624-25631
    • Betts, J.C.1    Cheshire, J.K.2    Akira, S.3    Kishimoto, T.4    Woo, P.5
  • 5
    • 0026050219 scopus 로고
    • Regulated expression of 3 C/EBP isoforms during adipose conversion of 3T3-L1 cells
    • Cao, Z. D., R. M. Umek, and S. L. McKnight. 1991. Regulated expression of 3 C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1538-1552.
    • (1991) Genes Dev. , vol.5 , pp. 1538-1552
    • Cao, Z.D.1    Umek, R.M.2    McKnight, S.L.3
  • 8
    • 0028796473 scopus 로고
    • Early responses of trans-activating factors to growth hormone in preadipocytes: Differential regulation of CCAAT enhancer-binding protein-beta (C/EBPβ) and C/EBPδ
    • Clarkson, R. W., C. M. Chen, S. Harrison, C. Wells, G. E. Muscat, and M. J. Waters. 1995. Early responses of trans-activating factors to growth hormone in preadipocytes: differential regulation of CCAAT enhancer-binding protein-beta (C/EBPβ) and C/EBPδ Mol. Endocrinol. 9:108-120.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 108-120
    • Clarkson, R.W.1    Chen, C.M.2    Harrison, S.3    Wells, C.4    Muscat, G.E.5    Waters, M.J.6
  • 11
    • 0025936177 scopus 로고
    • A liver-enriched transcriptional activator protein, Lap, and a transcriptional inhibitory protein, Lip, are translated from the same messenger RNA
    • Descombes, P., and U. Schibler. 1991. A liver-enriched transcriptional activator protein, Lap, and a transcriptional inhibitory protein, Lip, are translated from the same messenger RNA. Cell 67:569-579.
    • (1991) Cell , vol.67 , pp. 569-579
    • Descombes, P.1    Schibler, U.2
  • 12
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 14
    • 0027939611 scopus 로고
    • Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii
    • Gazzinelli, R. T., M. Wysocka, S. Hayashi, E. Y. Denkers, S. Hieny, P. Caspar, G. Trinchieri, and A. Sher. 1994. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 153:2533-2543.
    • (1994) J. Immunol. , vol.153 , pp. 2533-2543
    • Gazzinelli, R.T.1    Wysocka, M.2    Hayashi, S.3    Denkers, E.Y.4    Hieny, S.5    Caspar, P.6    Trinchieri, G.7    Sher, A.8
  • 15
    • 0028023045 scopus 로고
    • An NFIL-6 sequence near the transcriptional initiation site is necessary for the lipopolysaccharide induction of murine interleukin-1β
    • Godambe, S. A., D. D. Chaplin, T. Takova, and C. J. Bellone. 1994. An NFIL-6 sequence near the transcriptional initiation site is necessary for the lipopolysaccharide induction of murine interleukin-1β. DNA Cell Biol. 13: 561-569.
    • (1994) DNA Cell Biol. , vol.13 , pp. 561-569
    • Godambe, S.A.1    Chaplin, D.D.2    Takova, T.3    Bellone, C.J.4
  • 16
    • 0024502041 scopus 로고
    • Activation of HIV gene expression during monocyte differentiation by induction of NF-κB
    • Griffin, G. E., K. Leung, T. M. Folks, S. Kunkel, and G. J. Nabel. 1989. Activation of HIV gene expression during monocyte differentiation by induction of NF-κB. Nature 339:70-73.
    • (1989) Nature , vol.339 , pp. 70-73
    • Griffin, G.E.1    Leung, K.2    Folks, T.M.3    Kunkel, S.4    Nabel, G.J.5
  • 17
    • 0027295562 scopus 로고
    • C/EBP, NF-κB. and c-Ets family members and transcriptional regulation of the cell-specific and inducible macrophage inflammatory protein 1α immediate-early gene
    • Grove, M., and M. Plumb. 1993. C/EBP, NF-κB. and c-Ets family members and transcriptional regulation of the cell-specific and inducible macrophage inflammatory protein 1α immediate-early gene. Mol. Cell. Biol. 13:5276-5289.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5276-5289
    • Grove, M.1    Plumb, M.2
  • 19
    • 0027176524 scopus 로고
    • Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB
    • Henkel, T., T. Machleidt, I. Alkalay, M. Kronke, Y. Ben-Neriah, and P. A. Baeuerle. 1993. Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB. Nature 365:182-185.
    • (1993) Nature , vol.365 , pp. 182-185
    • Henkel, T.1    Machleidt, T.2    Alkalay, I.3    Kronke, M.4    Ben-Neriah, Y.5    Baeuerle, P.A.6
  • 20
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 22
    • 0028973003 scopus 로고
    • IL-1β is required for IL-12 to induce production of IFN-γ by NK cells. A role for IL-1β in the T cell-independent mechanism or resistance against intracellular pathogens
    • Hunter, C. A., R. Chizzonite, and J. S. Remington. 1995. IL-1β is required for IL-12 to induce production of IFN-γ by NK cells. A role for IL-1β in the T cell-independent mechanism or resistance against intracellular pathogens. J. Immunol. 155:4347-4354.
    • (1995) J. Immunol. , vol.155 , pp. 4347-4354
    • Hunter, C.A.1    Chizzonite, R.2    Remington, J.S.3
  • 23
    • 0027454228 scopus 로고
    • Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-κB
    • Kerr, L. D., L. J. Ransone, P. Wamsley, M. J. Schmitt, T. G. Boyer, Q. Zhou, A. J. Berk, and I. M. Verma. 1993. Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-κB. Nature 365:412-419.
    • (1993) Nature , vol.365 , pp. 412-419
    • Kerr, L.D.1    Ransone, L.J.2    Wamsley, P.3    Schmitt, M.J.4    Boyer, T.G.5    Zhou, Q.6    Berk, A.J.7    Verma, I.M.8
  • 24
    • 0028316546 scopus 로고
    • Differential regulation of interleukin-12 (IL-12), tumor necrosis factor alpha, and IL-1β production in human myeloid leukemia cell lines and peripheral blood mononuclear cells
    • Kubin, M., J. M. Chow, and G. Trinchieri. 1994. Differential regulation of interleukin-12 (IL-12), tumor necrosis factor alpha, and IL-1β production in human myeloid leukemia cell lines and peripheral blood mononuclear cells. Blood 83:1847-1855.
    • (1994) Blood , vol.83 , pp. 1847-1855
    • Kubin, M.1    Chow, J.M.2    Trinchieri, G.3
  • 25
    • 0026730105 scopus 로고
    • The p50 subunit of NF-κB associates with the NF-IL6 transcription factor
    • LeClair, K. P., M. A. Blanar, and P. A. Sharp. 1992. The p50 subunit of NF-κB associates with the NF-IL6 transcription factor. Proc. Natl. Acad. Sci. USA 89:8145-8149.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8145-8149
    • LeClair, K.P.1    Blanar, M.A.2    Sharp, P.A.3
  • 26
    • 0027275497 scopus 로고
    • The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver
    • Li, Y. S., K. Hayakawa, and R. R. Hardy. 1993. The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J. Exp. Med. 178:951-960.
    • (1993) J. Exp. Med. , vol.178 , pp. 951-960
    • Li, Y.S.1    Hayakawa, K.2    Hardy, R.R.3
  • 27
    • 0025943384 scopus 로고
    • LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocytespecific genes
    • Lo, K., N. R. Landau, and S. T. Smale. 1991. LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocytespecific genes. Mol. Cell. Biol. 11:5229-5243.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5229-5243
    • Lo, K.1    Landau, N.R.2    Smale, S.T.3
  • 30
    • 0027453552 scopus 로고
    • Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
    • Matsusaka, T., K. Fujikawa, Y. Nishio, N. Mukaida, K. Matsushima, T. Kishimoto, and S. Akira. 1993. Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc. Natl. Acad. Sci. USA 90:10193-10197.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10193-10197
    • Matsusaka, T.1    Fujikawa, K.2    Nishio, Y.3    Mukaida, N.4    Matsushima, K.5    Kishimoto, T.6    Akira, S.7
  • 31
    • 0028972558 scopus 로고
    • Differential utilization of IFN-γ-responsive elements in two maturationally distinct macrophage cell lines
    • McDowell, M. A., D. M. Lucas, C. M. Nicolet, and D. M. Paulnock. 1995. Differential utilization of IFN-γ-responsive elements in two maturationally distinct macrophage cell lines. J. Immunol. 155:4933-4938.
    • (1995) J. Immunol. , vol.155 , pp. 4933-4938
    • McDowell, M.A.1    Lucas, D.M.2    Nicolet, C.M.3    Paulnock, D.M.4
  • 32
    • 0025941621 scopus 로고
    • AMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription
    • Metz, R., and E. Ziff. 1991. cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription. Genes Dev. 5:1754-1766.
    • (1991) Genes Dev. , vol.5 , pp. 1754-1766
    • Metz, R.1    Ziff, E.2
  • 33
    • 0029866697 scopus 로고    scopus 로고
    • Progesterone inhibits inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages
    • Miller, L., E. W. Alley, W. J. Murphy, S. W. Russell, and J. S. Hunt. 1996. Progesterone inhibits inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages. J. Leukocyte Biol. 59:442-450.
    • (1996) J. Leukocyte Biol. , vol.59 , pp. 442-450
    • Miller, L.1    Alley, E.W.2    Murphy, W.J.3    Russell, S.W.4    Hunt, J.S.5
  • 34
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mossman, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mossman, T.R.1    Coffman, R.L.2
  • 36
    • 0029156782 scopus 로고
    • CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells
    • Nerlov, C., and E. B. Ziff. 1995. CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells. EMBO J. 14:4318-4328.
    • (1995) EMBO J. , vol.14 , pp. 4318-4328
    • Nerlov, C.1    Ziff, E.B.2
  • 37
    • 0028028858 scopus 로고
    • Promoter analysis of an interferon-inducible gene associated with macrophage activation
    • Nicolet, C. M., and D. M. Paulnock. 1994. Promoter analysis of an interferon-inducible gene associated with macrophage activation. J. Immunol. 152: 153-162.
    • (1994) J. Immunol. , vol.152 , pp. 153-162
    • Nicolet, C.M.1    Paulnock, D.M.2
  • 38
    • 0024002556 scopus 로고
    • Luciferase reporter gene vectors for analysis of promoters and enhancers
    • Nordeen, S. K. 1988. Luciferase reporter gene vectors for analysis of promoters and enhancers. BioTechniques 6:454-458.
    • (1988) BioTechniques , vol.6 , pp. 454-458
    • Nordeen, S.K.1
  • 39
    • 0027214319 scopus 로고
    • CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials
    • Ossipow, V., P. Descombes, and U. Schibler. 1993. CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials. Proc. Natl. Acad. Sci. USA 90:8219-8223.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8219-8223
    • Ossipow, V.1    Descombes, P.2    Schibler, U.3
  • 40
    • 0344627945 scopus 로고
    • Oligonucleotide that binds nuclear factor NF-κB acts as a lymphoid-specific and inducible enhancer element
    • Pierce, J. W., M. Lenardo, and D. Baltimore. 1988. Oligonucleotide that binds nuclear factor NF-κB acts as a lymphoid-specific and inducible enhancer element. Proc. Natl. Acad. Sci. USA 85:1482-1486.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1482-1486
    • Pierce, J.W.1    Lenardo, M.2    Baltimore, D.3
  • 42
    • 0028170158 scopus 로고
    • C/EBPβ regulation of the tumor necrosis factor alpha gene
    • Pope, R. M., A. Leutz, and S. A. Ness. 1994. C/EBPβ regulation of the tumor necrosis factor alpha gene. J. Clin. Invest. 94:1449-1455.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1449-1455
    • Pope, R.M.1    Leutz, A.2    Ness, S.A.3
  • 43
    • 0019793022 scopus 로고
    • Analysis of interferon mRNA in human fibroblast cells induced to produce interferon
    • Raj, N. B., and P. M. Pitha. 1981. Analysis of interferon mRNA in human fibroblast cells induced to produce interferon. Proc. Natl. Acad. Sci. USA 78:7426-7430.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 7426-7430
    • Raj, N.B.1    Pitha, P.M.2
  • 44
    • 0027217386 scopus 로고
    • The two C/EBP isoforms. IL-6DBP/NF-IL6 and C/EBPδ/NF-IL6β, are induced by IL-6 to promote acute phase gene transcription via different mechanisms
    • Ramji, D. P., A. Vitelli, F. Tronche, R. Cortese, and G. Ciliberto. 1993. The two C/EBP isoforms. IL-6DBP/NF-IL6 and C/EBPδ/NF-IL6β, are induced by IL-6 to promote acute phase gene transcription via different mechanisms. Nucleic Acids Res. 21:289-294.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 289-294
    • Ramji, D.P.1    Vitelli, A.2    Tronche, F.3    Cortese, R.4    Ciliberto, G.5
  • 45
    • 0028960452 scopus 로고
    • Interaction of the COOH-terminal transactivation domain of p65 NF-κB with TATA-binding protein, transcription factor IIB, and coactivators
    • Schmitz, M. L., G. Stelzer, H. Altmann, M. Meisterernst, and P. A. Baeuerle. 1995. Interaction of the COOH-terminal transactivation domain of p65 NF-κB with TATA-binding protein, transcription factor IIB, and coactivators. J. Biol. Chem. 270:7219-7226.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7219-7226
    • Schmitz, M.L.1    Stelzer, G.2    Altmann, H.3    Meisterernst, M.4    Baeuerle, P.A.5
  • 47
    • 0026758202 scopus 로고
    • A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells
    • Scott, L. M., C. I. Civin, P. Rorth, and A. D. Friedman. 1992. A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells. Blood 80:1725-1735.
    • (1992) Blood , vol.80 , pp. 1725-1735
    • Scott, L.M.1    Civin, C.I.2    Rorth, P.3    Friedman, A.D.4
  • 49
    • 0030266857 scopus 로고    scopus 로고
    • Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease
    • Seder, R. A., B. L. Kelsall, and D. Jankovic. 1996. Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease. J. Immunol. 157:2745-2748.
    • (1996) J. Immunol. , vol.157 , pp. 2745-2748
    • Seder, R.A.1    Kelsall, B.L.2    Jankovic, D.3
  • 50
    • 0027971331 scopus 로고
    • Cytokine patterns at the site of mycobacterial infection
    • Sieling, P. A., and R. L. Modlin. 1994. Cytokine patterns at the site of mycobacterial infection. Immunobiology 191:378-387.
    • (1994) Immunobiology , vol.191 , pp. 378-387
    • Sieling, P.A.1    Modlin, R.L.2
  • 51
    • 0030051658 scopus 로고    scopus 로고
    • Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines
    • Skeen, M. J., M. A. Miller, T. M. Shinnick, and H. K. Ziegler. 1996. Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines. J. Immunol. 156:1196-1206.
    • (1996) J. Immunol. , vol.156 , pp. 1196-1206
    • Skeen, M.J.1    Miller, M.A.2    Shinnick, T.M.3    Ziegler, H.K.4
  • 52
    • 0024557039 scopus 로고
    • The "initiator" as a transcription control element
    • Smale, S. T., and D. Baltimore. 1989. The "initiator" as a transcription control element. Cell 57:103-113.
    • (1989) Cell , vol.57 , pp. 103-113
    • Smale, S.T.1    Baltimore, D.2
  • 53
    • 0030064036 scopus 로고    scopus 로고
    • Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit
    • Snidjers, A., C. M. Hilkens, T. C. van der Pouw Kraan, M. Engel, L. A. Aarden, and M. L. Kapsenberg. 1996. Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit, J. Immunol. 156:1207-1212.
    • (1996) J. Immunol. , vol.156 , pp. 1207-1212
    • Snidjers, A.1    Hilkens, C.M.2    Van Der Pouw Kraan, T.C.3    Engel, M.4    Aarden, L.A.5    Kapsenberg, M.L.6
  • 54
    • 0027465288 scopus 로고
    • Electroporation and DNA-dependent cell death in murine macrophages
    • Stacey, K. J., I. L. Ross, and D. A. Hume. 1993. Electroporation and DNA-dependent cell death in murine macrophages. Immunol. Cell Biol. 71:75-85.
    • (1993) Immunol. Cell Biol. , vol.71 , pp. 75-85
    • Stacey, K.J.1    Ross, I.L.2    Hume, D.A.3
  • 55
    • 0027379055 scopus 로고
    • Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-κB
    • Stein, B., and A. S. Baldwin, Jr. 1993. Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-κB. Mol. Cell. Biol. 13:7191-7198.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7191-7198
    • Stein, B.1    Baldwin Jr., A.S.2
  • 56
    • 0027316201 scopus 로고
    • Functional and physical associations between NF-κB and C/EBP family members: A Rel domain-bZIP interaction
    • Stein, B., P. C. Cogswell, and A. S. Baldwin, Jr. 1993. Functional and physical associations between NF-κB and C/EBP family members: a Rel domain-bZIP interaction. Mol. Cell. Biol. 13:3964-3974.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3964-3974
    • Stein, B.1    Cogswell, P.C.2    Baldwin Jr., A.S.3
  • 58
    • 0027186357 scopus 로고
    • Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain
    • Trautwein, C., C. Caelles, P. van der Geer, T. Hunter, M. Karin, and M. Chojkier. 1993. Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain. Nature 364:544-547.
    • (1993) Nature , vol.364 , pp. 544-547
    • Trautwein, C.1    Caelles, C.2    Van Der Geer, P.3    Hunter, T.4    Karin, M.5    Chojkier, M.6
  • 59
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251-276.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 60
    • 0028209541 scopus 로고
    • Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-γ
    • Tripp, C. S., M. K. Gately, J. Hakimi, P. Ling, and E. R. Unanue. 1994. Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-γ. J. Immunol. 152:1883-1887.
    • (1994) J. Immunol. , vol.152 , pp. 1883-1887
    • Tripp, C.S.1    Gately, M.K.2    Hakimi, J.3    Ling, P.4    Unanue, E.R.5
  • 61
    • 0024370748 scopus 로고
    • Scissors-grip model for DNA recognition by a family of leucine zipper proteins
    • Vinson, C. R., P. B. Sigler, and S. L. McKnight. 1989. Scissors-grip model for DNA recognition by a family of leucine zipper proteins. Science 246:911-916.
    • (1989) Science , vol.246 , pp. 911-916
    • Vinson, C.R.1    Sigler, P.B.2    McKnight, S.L.3
  • 62
    • 0029134126 scopus 로고
    • The C/EBP family of transcription factors
    • Wedel, A., and H. W. Ziegler-Heitbrock. 1995. The C/EBP family of transcription factors. Immunobiology 193:171-185.
    • (1995) Immunobiology , vol.193 , pp. 171-185
    • Wedel, A.1    Ziegler-Heitbrock, H.W.2
  • 64
    • 8944233870 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promotes nuclear localization of cytokine-inducible CCAAT/enhancer binding protein isoforms in hepatocytes
    • Yin, M., S. Q. Yang, H. Z. Lin, M. D. Lane, S. Chatterjee, and A. M. Diehl. 1996. Tumor necrosis factor alpha promotes nuclear localization of cytokine-inducible CCAAT/enhancer binding protein isoforms in hepatocytes. J. Biol. Chem. 271:17974-17978.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17974-17978
    • Yin, M.1    Yang, S.Q.2    Lin, H.Z.3    Lane, M.D.4    Chatterjee, S.5    Diehl, A.M.6
  • 66
    • 0025806611 scopus 로고
    • Superinduction of IL-2 gene transcription in the presence of cycloheximide
    • Zubiaga, A. M., E. Munoz, and B. T. Huber. 1991. Superinduction of IL-2 gene transcription in the presence of cycloheximide. J. Immunol. 146:3857-3863.
    • (1991) J. Immunol. , vol.146 , pp. 3857-3863
    • Zubiaga, A.M.1    Munoz, E.2    Huber, B.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.