메뉴 건너뛰기




Volumn 40, Issue 5-6, 1997, Pages 304-321

Recent advances in antiretroviral therapy and HIV infection monitoring

Author keywords

Antiretroviral therapy; Dideoxynucleoside analogues; Drug resistance; Nonnucleoside reverse transcriptase inhibitors; Protease inhibitors; Viral load

Indexed keywords

ABACAVIR; ADEFOVIR DIPIVOXIL; ANTIRETROVIRUS AGENT; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 2642640455     PISSN: 03005526     EISSN: 14230100     Source Type: Journal    
DOI: 10.1159/000150564     Document Type: Article
Times cited : (24)

References (114)
  • 9
    • 0030842430 scopus 로고    scopus 로고
    • Antihuman immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adcfovir dipivoxil (9-(2-(bis-pivaloxymethyl)-phospho-nylmcthoxvjadenine in HIV-infected patients
    • Barditch-Crovo P, Toole J, Hendrix CW, Cun-dv KC, Ebcling D, JatTc HS, Lietman PS: Antihuman immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adcfovir dipivoxil (9-(2-(bis-pivaloxymethyl)-phospho-nylmcthoxvjadenine in HIV-infected patients, J Infect Dis 1997;176:406-413.
    • (1997) J Infect Dis , vol.176 , pp. 406-413
    • Barditch-Crovo, P.1    Toole, J.2    Hendrix, C.W.3    Cun-Dv, K.C.4    Ebcling, D.5    Jattc, H.S.6    Lietman, P.S.7
  • 12
    • 85025545440 scopus 로고    scopus 로고
    • Update zur antiretroviralcn Therapic, Berlin
    • lnfektionsepidemiologischc Forschung: Update zur antiretroviralcn Therapic, Berlin, Robert Koch Institut, 1997. vol 2. pp 83-85.
    • (1997) Robert Koch Institut , vol.2 , pp. 83-85
  • 13
    • 0025837774 scopus 로고
    • Broad spectrum anti-DNA virus and anti-retrovirus activity of phosphonylme-thoxyalkylpurincs and -pyrimidines
    • De Clercq E: Broad spectrum anti-DNA virus and anti-retrovirus activity of phosphonylme-thoxyalkylpurincs and -pyrimidines, Biochem Pharmacol 1991:42:963-972.
    • (1991) Biochem Pharmacol , vol.42 , pp. 963-972
    • De Clercq, E.1
  • 16
    • 0029838243 scopus 로고    scopus 로고
    • Mutations in retroviral genes associated with drug resistance
    • Schinazi RF, Larder BA, Mellors JW: Mutations in retroviral genes associated with drug resistance, Antiviral News 1996:4:95-107.
    • (1996) Antiviral News , vol.4 , pp. 95-107
    • Schinazi, R.F.1    Larder, B.A.2    Mellors, J.W.3
  • 18
    • 0027285372 scopus 로고
    • Rapid in vitro selection of human immunodeficiency virus type I resistant to 3'-thiacytidine inhibitors due to a mutation in the YMMD region of reverse transcriptase
    • Tisdale M, Kemp SD, Parray NR, Larder BA: Rapid in vitro selection of human immunodeficiency virus type I resistant to 3'-thiacytidine inhibitors due to a mutation in the YMMD region of reverse transcriptase, Proc Natl Acad Sci USA 1993:90:5653-5656.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5653-5656
    • Tisdale, M.1    Kemp, S.D.2    Parray, N.R.3    Larder, B.A.4
  • 19
    • 0028828540 scopus 로고
    • Development of zidovudine resistance mutations in patients receiving prolonged didanosinc monotherapy
    • Demctcr LM, Nawaz T, Morse G, Dolin R, Dexter A, Gerondclis P, Reichman RC: Development of zidovudine resistance mutations in patients receiving prolonged didanosinc monotherapy, J Infect Dis 1995;172:1480-1485.
    • (1995) J Infect Dis , vol.172 , pp. 1480-1485
    • Demctcr, L.M.1    Nawaz, T.2    Morse, G.3    Dolin, R.4    Dexter, A.5    Gerondclis, P.6    Reichman, R.C.7
  • 22
    • 0029028067 scopus 로고
    • Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
    • Larder BA, Kemp SD, Harrigan PR: Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy, Science 1995:269:696-699.
    • (1995) Science , vol.269 , pp. 696-699
    • Larder, B.A.1    Kemp, S.D.2    Harrigan, P.R.3
  • 24
    • 0030818643 scopus 로고    scopus 로고
    • Lamivudine-resistani human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-rcsistant to zidovudine in vivo
    • Nijhuis M, Schuurman R, de Jong D, van Lecuwen R, Lange J, Danner S, Kculen W, de Groot T, Boucher CAB: Lamivudine-resistani human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-rcsistant to zidovudine in vivo, J Infect Dis 1997;176:398-405.
    • (1997) J Infect Dis , vol.176 , pp. 398-405
    • Nijhuis, M.1    Schuurman, R.2    De Jong, D.3    Van Lecuwen, R.4    Lange, J.5    Danner, S.6    Kculen, W.7    De Groot, T.8    Boucher, C.9
  • 25
    • 0027398296 scopus 로고
    • Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidinc, dideoxv-cytidinc, and dideoxyinosine: An in vitro comparative study
    • Shirasaka T, Yarchoan R, O'Brien MC, Hus-son RN, Anderson BD, Kojima E, Shimada T, Broder S, Mitsuya H: Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidinc, dideoxv-cytidinc, and dideoxyinosine: an in vitro comparative study, Proc Natl Acad Sci USA 1993: 90:562-566.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 562-566
    • Shirasaka, T.1    Yarchoan, R.2    O'brien, M.C.3    Hus-Son, R.N.4    Erson, B.D.5    Kojima, E.6    Shimada, T.7    Broder, S.8    Mitsuya, H.9
  • 32
    • 0029897567 scopus 로고    scopus 로고
    • Tarplcy WG: (Alky-lamino)piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1 IIIB with reduced replication phcnotvpcs
    • Olmsted RA, Slade DE, Kopta LA, Poppe SM, Poel TJ, Newport SW, Rank KB, Biles C, Morgc RA, Ducweke TJ, Yagi Y, Romero DL, Thomas RC, Sharma SK, Tarplcy WG: (Alky-lamino)piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1 IIIB with reduced replication phcnotvpcs, J Virol 1996:70:3698-3705.
    • (1996) J Virol , vol.70 , pp. 3698-3705
    • Olmsted, R.A.1    Slade, D.E.2    Kopta, L.A.3    Poppe, S.M.4    Poel, T.J.5    Newport, S.W.6    Rank, K.B.7    Biles, C.8    Morgc, R.A.9    Ducweke, T.J.10    Yagi, Y.11    Romero, D.L.12    Thomas, R.C.13    Sharma, S.K.14
  • 35
    • 0030997937 scopus 로고    scopus 로고
    • Randomised trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: The CAESAR trial
    • CAESAR-Coordinating-Committee: Randomised trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: The CAESAR trial, Lancet 1997:349:1413-1421.
    • (1997) Lancet , vol.349 , pp. 1413-1421
  • 37
    • 0029011342 scopus 로고
    • Activity of various thio-carboxanilide derivatives against wild-type and several mutant human immunodeficiency virus type 1 strains
    • Balzarini J, Brouwer WG, Felauer EE, De Clereq E, Karlsson A: Activity of various thio-carboxanilide derivatives against wild-type and several mutant human immunodeficiency virus type 1 strains, Antiviral Res 1995:27:219-236.
    • (1995) Antiviral Res , vol.27 , pp. 219-236
    • Balzarini, J.1    Brouwer, W.G.2    Felauer, E.E.3    De Clereq, E.4    Karlsson, A.5
  • 41
    • 0027231438 scopus 로고
    • Chen 1SY, Stevenson M, Tarpley WG: A mutation in reverse transcriptase of bis(hetcroaryl)piperazinc-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors
    • Duewcke TJ, Pushkarskaya T, Poppe SM, Swa-ncy SM, Zhao JQ, Chen 1SY, Stevenson M, Tarpley WG: A mutation in reverse transcriptase of bis(hetcroaryl)piperazinc-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors, Proc Natl Acad Sci USA 1993: 90:4713-4717.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4713-4717
    • Duewcke, T.J.1    Pushkarskaya, T.2    Poppe, S.M.3    Swa-Ncy, S.M.4    Zhao, J.Q.5
  • 42
    • 0030070683 scopus 로고    scopus 로고
    • Selective pressure of a quinoxaline nonnucleosidc inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-I replication results in the emergence of nucleoside RT-inhibitor-specific (RT Lcu-74-> Val or lie and Val-75 ->Leu or lie) HIV-I mutants
    • Kleim J-P, Rosber M, Winkler I, Paessens A, Kirsch R, Hsiou Y, Arnold E, Riess G: Selective pressure of a quinoxaline nonnucleosidc inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-I replication results in the emergence of nucleoside RT-inhibitor-specific (RT Lcu-74-> Val or lie and Val-75 ->Leu or lie) HIV-I mutants, Proc Natl Acad Sci USA 1996:93:34-38.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 34-38
    • Kleim, J.-P.1    Rosber, M.2    Winkler, I.3    Paessens, A.4    Kirsch, R.5    Hsiou, Y.6    Arnold, E.7    Riess, G.8
  • 43
    • 0029593364 scopus 로고
    • Knocking out human immunodeficiency virus through non-nuclco-side reverse inhibitors used as single agents or in combinations: A paradigm for the cure of AIDS
    • De Clercq E, Balzarini J: Knocking out human immunodeficiency virus through non-nuclco-side reverse inhibitors used as single agents or in combinations: A paradigm for the cure of AIDS, Farmaco 1995;50:735-747.
    • (1995) Farmaco , vol.50 , pp. 735-747
    • De Clercq, E.1    Balzarini, J.2
  • 44
    • 0031024623 scopus 로고    scopus 로고
    • HiV-1 protcase inhibitors, A review for clinicians
    • Deeks SG, Smith M, Holodniy M, Kahn JO: HiV-1 protcase inhibitors, A review for clinicians, JAMA 1997;277:145-153.
    • (1997) JAMA , vol.277 , pp. 145-153
    • Deeks, S.G.1    Smith, M.2    Holodniy, M.3    Kahn, J.O.4
  • 50
    • 0029897059 scopus 로고    scopus 로고
    • Saquinavir, A review of its pharmacology and clinical potential in the management of HIV infection
    • Noble S, Faulds D: Saquinavir, A review of its pharmacology and clinical potential in the management of HIV infection, Drugs 1996;52: 93-112.
    • (1996) Drugs , vol.52 , pp. 93-112
    • Noble, S.1    Faulds, D.2
  • 54
    • 0030769354 scopus 로고    scopus 로고
    • Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites
    • Zhang YM, Imamichi I, Imamichi T, Lane HC, Falloon J, Vasudevachari MB, Salzman NP: Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites, J Virol 1997; 71:6662-6670.
    • (1997) J Virol , vol.71 , pp. 6662-6670
    • Zhang, Y.M.1    Imamichi, I.2    Imamichi, T.3    Lane, H.C.4    Falloon, J.5    Vasudevachari, M.B.6    Salzman, N.P.7
  • 56
    • 0028943992 scopus 로고
    • In vitro emergence of HIV-1 variants resistant to multiple protcase inhibitors
    • Condra JH, Schleif WA, Blahy OM: In vitro emergence of HIV-1 variants resistant to multiple protcase inhibitors, Nature 1995:374:569-571.
    • (1995) Nature , vol.374 , pp. 569-571
    • Condra, J.H.1    Schleif, W.A.2    Blahy, O.M.3
  • 57
    • 0030012398 scopus 로고    scopus 로고
    • Resistance-related mutations in the HIV-1 protease gene of patients treated for I year with the protcasc inhibitor ritonavir (ABT-538)
    • Schmit J-C, Ruiz L, Clolct B, Raventos A, Tor J, Leonard J, Dcsmvter J, De Clcrcq E, Van-dammc A-M: Resistance-related mutations in the HIV-1 protease gene of patients treated for I year with the protcasc inhibitor ritonavir (ABT-538), AIDS 1996:10:995-999.
    • (1996) AIDS , vol.10 , pp. 995-999
    • Schmit, J.-C.1    Ruiz, L.2    Clolct, B.3    Raventos, A.4    Tor, J.5    Leonard, J.6    Dcsmvter, J.7    De Clcrcq, E.8    Van-Dammc, A.-M.9
  • 62
    • 0030830661 scopus 로고    scopus 로고
    • Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
    • Schols D, Struyf S, Van Damme J, Estc JA, Henson G, De Clercq E: Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. J Exp Med 1997: 186:1383-1388.
    • (1997) J Exp Med , vol.186 , pp. 1383-1388
    • Schols, D.1    Struyf, S.2    Van Damme, J.3    Estc, J.A.4    Henson, G.5    De Clercq, E.6
  • 66
    • 0030902816 scopus 로고    scopus 로고
    • HIV intcgrase: A target for AIDS therapeutics
    • Thomas M, Brady L: HIV intcgrase: A target for AIDS therapeutics, Trends Biotechno! 1997:15:167-172.
    • (1997) Trends Biotechno! , vol.15 , pp. 167-172
    • Thomas, M.1    Brady, L.2
  • 70
    • 0030935397 scopus 로고    scopus 로고
    • The multiple inhibitory mechanisms of GEM91. A gag anlisense phosphoro-thioate oligonucleotide, for human immunodeficiency virus type 1
    • Yantaguchi K, Papp B, Zhang D, Ali AN, Agra-wal S, Bvm RA: The multiple inhibitory mechanisms of GEM91. a gag anlisense phosphoro-thioate oligonucleotide, for human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1997;13:545-554.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 545-554
    • Yantaguchi, K.1    Papp, B.2    Zhang, D.3    Ali, A.N.4    Agra-Wal, S.5    Bvm, R.A.6
  • 71
  • 78
    • 0030567824 scopus 로고    scopus 로고
    • A randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine with zidovudine alone in HIV-infected individuals
    • Delta-coordinating-committee, Delta: A randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine with zidovudine alone in HIV-infected individuals, Lancet 1996:348:283-291.
    • (1996) Lancet , vol.348 , pp. 283-291
  • 80
    • 0028344275 scopus 로고
    • MRC/ARNS randomised double-blind controlled trial of immediate and deferred zidovudine in symptom-free HIV infection
    • Concorde-coordinalion-committee, Concorde: MRC/ARNS randomised double-blind controlled trial of immediate and deferred zidovudine in symptom-free HIV infection, Lancet 1994:343:871-881.
    • (1994) Lancet , vol.343 , pp. 871-881
  • 83
    • 0030935802 scopus 로고    scopus 로고
    • British HIV association guidelines for antiretroviral treatment of HIV seropositive individuals
    • BHIVA-Guidelincs-Co-ordinating-Commit-tee: British HIV association guidelines for antiretroviral treatment of HIV seropositive individuals, Lancet 1997:349:1086-1092.
    • (1997) Lancet , vol.349 , pp. 1086-1092
  • 85
    • 0030573421 scopus 로고    scopus 로고
    • Provisional public health service recommendations for chemoprophylaxis after occupational exposure to HIV
    • Centers-for-Disease-Control-and-Prevention, Update: Provisional public health service recommendations for chemoprophylaxis after occupational exposure to HIV, MMWR 1996:45: 468-472.
    • (1996) MMWR , vol.45 , pp. 468-472
  • 93
    • 0030999422 scopus 로고    scopus 로고
    • Subtype-specific problems with quantification of plasma HIV-1 RNA
    • Alaeus A, Lidman K, Sonncrsborg A, Albert J: Subtype-specific problems with quantification of plasma HIV-1 RNA, AIDS 1997:1 1:54-75.
    • (1997) AIDS , vol.1 , Issue.1 , pp. 54-75
    • Alaeus, A.1    Lidman, K.2    Sonncrsborg, A.3    Albert, J.4
  • 97
    • 2642624031 scopus 로고
    • Light-generated oligonucleotide arrays for rapid DNA sequence analysis
    • Pease AC, Solas D, Sullivan EJ: Light-generated oligonucleotide arrays for rapid DNA sequence analysis, Proc Natl Acad Sci USA 1994: 365:451-453.
    • (1994) Proc Natl Acad Sci USA , vol.365 , pp. 451-453
    • Pease, A.C.1    Solas, D.2    Sullivan, E.J.3
  • 102
    • 0031046755 scopus 로고    scopus 로고
    • Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene
    • Stuyver L, Wvseur A, Romboul A: Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene, Antimicrob Agents Chemother 1997;41:284-291.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 284-291
    • Stuyver, L.1    Wvseur, A.2    Romboul, A.3
  • 105
    • 0024508058 scopus 로고
    • HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy
    • Larder BA, Darby G, Richman DD: HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy, Science 1989:243:1731-1734.
    • (1989) Science , vol.243 , pp. 1731-1734
    • Larder, B.A.1    Darby, G.2    Richman, D.D.3
  • 107
    • 0016379917 scopus 로고
    • Relationships between inhibition constants and fractional inhibitions in enzyme-catalyzed reactions with different numbers of reactants, different reaction mechanisms, and different types of mechanisms of inhibition
    • Chou TC: Relationships between inhibition constants and fractional inhibitions in enzyme-catalyzed reactions with different numbers of reactants, different reaction mechanisms, and different types of mechanisms of inhibition, Mol Pharmacol 1974; 10:235-247.
    • (1974) Mol Pharmacol , vol.10 , pp. 235-247
    • Chou, T.C.1
  • 109
    • 0028085161 scopus 로고
    • Recombinant virus assay: A rapid, phenotypic assay for assessment of drug susceptibility of human immunodeficiency virus type 1 isolates
    • Kellam P, Larder BA: Recombinant virus assay: A rapid, phenotypic assay for assessment of drug susceptibility of human immunodeficiency virus type 1 isolates, Antimicrob Agents Chemother 1994;38:23-30.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 23-30
    • Kellam, P.1    Larder, B.A.2
  • 110
    • 0029087303 scopus 로고
    • Analysis of resistance to human immunodeficiency virus type 1 protcasc inhibitors by using matched bacterial expression and proviral infection vectors
    • Maschera B, Furfine E, Blair ED: Analysis of resistance to human immunodeficiency virus type 1 protcasc inhibitors by using matched bacterial expression and proviral infection vectors, J Virol 1995:69:5431-5436.
    • (1995) J Virol , vol.69 , pp. 5431-5436
    • Maschera, B.1    Furfine, E.2    Blair, E.D.3
  • 112
    • 0025865730 scopus 로고
    • Functional characterization of RN'A-dependcnt DNA polymerase and RNase activities of a recombinant HIV reverse transcriptase
    • Tan CK, Zhang KM, So AG: Functional characterization of RN'A-dependcnt DNA polymerase and RNase activities of a recombinant HIV reverse transcriptase, Biochemistry 1991:30:2651-2655.
    • (1991) Biochemistry , vol.30 , pp. 2651-2655
    • Tan, C.K.1    Zhang, K.M.2    So, A.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.