-
1
-
-
0029644513
-
Safety and activity of saquinavir in HIV infection
-
Kitchen VS, Skinner C, Ariyoshi K, et al.: Safety and activity of saquinavir in HIV infection. Lancet 1995, 345:952-955.
-
(1995)
Lancet
, vol.345
, pp. 952-955
-
-
Kitchen, V.S.1
Skinner, C.2
Ariyoshi, K.3
-
2
-
-
0028968902
-
ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans
-
Kempf DJ, Marsh KC, Denissen JF, et al.: ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans. Proc Natl Acad Sci USA, 92:2484-2488.
-
Proc Natl Acad Sci USA
, vol.92
, pp. 2484-2488
-
-
Kempf, D.J.1
Marsh, K.C.2
Denissen, J.F.3
-
3
-
-
0028222149
-
L-735, 524: An orally bioavailable human immunodeficiency virus type 1 protease inhibitor
-
Vacca JP, Dorsey BD, Schleif WA, et al.: L-735, 524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor. Proc Natl Acad Sci USA 1994, 91:4096-4100.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4096-4100
-
-
Vacca, J.P.1
Dorsey, B.D.2
Schleif, W.A.3
-
4
-
-
0028874048
-
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
-
Ho DD, Neuman AU, Perelson AS, et al.: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995, 373:123-126.
-
(1995)
Nature
, vol.373
, pp. 123-126
-
-
Ho, D.D.1
Neuman, A.U.2
Perelson, A.S.3
-
5
-
-
0028943992
-
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
-
Condra JH, Schleif WA, Blahy OM, et al.: In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 1995, 374:569-571.
-
(1995)
Nature
, vol.374
, pp. 569-571
-
-
Condra, J.H.1
Schleif, W.A.2
Blahy, O.M.3
-
6
-
-
0029070347
-
Resistance of HIV type 1 to proteinase inhibitor Ro 31-8959
-
Eberle J, Bechowsky B, Rose D, et al.: Resistance of HIV type 1 to proteinase inhibitor Ro 31-8959. AIDS Res Hum Retroviruses 1995, 11:671-676.
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, pp. 671-676
-
-
Eberle, J.1
Bechowsky, B.2
Rose, D.3
-
7
-
-
0028855166
-
Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance
-
Mellors JW, Larder BA, Schinazi RF: Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int Antiviral News 1995, 3:8-12.
-
(1995)
Int Antiviral News
, vol.3
, pp. 8-12
-
-
Mellors, J.W.1
Larder, B.A.2
Schinazi, R.F.3
-
8
-
-
0028854676
-
Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor
-
Markowitz M, Mo H, Kempf DL, et al.: Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor. J Virol 1995, 69:701-706.
-
(1995)
J Virol
, vol.69
, pp. 701-706
-
-
Markowitz, M.1
Mo, H.2
Kempf, D.L.3
-
9
-
-
0028136695
-
Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates
-
Japour AJ, Fiscus SA, Arduino JM, et al.: Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates. J Clin Microbiol 1994, 32:2291-2294.
-
(1994)
J Clin Microbiol
, vol.32
, pp. 2291-2294
-
-
Japour, A.J.1
Fiscus, S.A.2
Arduino, J.M.3
-
10
-
-
0027270541
-
Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates
-
Japour AJ, Mayers DL, Johnson VA, et al.: Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates. Antimicrob Agents Chemother 1993, 37:1095-1101.
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 1095-1101
-
-
Japour, A.J.1
Mayers, D.L.2
Johnson, V.A.3
-
11
-
-
3142633092
-
Evolution of resistance to the protease inhibitor ritonavir (ABT-538) in HIV-infected patients
-
Sardinia, July [abstract 69]
-
Molla A, Boucher C, Korneyeva M, et al.: Evolution of resistance to the protease inhibitor ritonavir (ABT-538) in HIV-infected patients. Fourth International Workshop on HIV Drug Resistance. Sardinia, July 1995 [abstract 69].
-
(1995)
Fourth International Workshop on HIV Drug Resistance
-
-
Molla, A.1
Boucher, C.2
Korneyeva, M.3
-
12
-
-
0028846165
-
Safety, pharmacokinetics, and preliminary efficacy of ritonavir, an inhibitor of HIV-1 protease
-
Danner SA, Carr A, Leonard JM, et al.: Safety, pharmacokinetics, and preliminary efficacy of ritonavir, an inhibitor of HIV-1 protease. N Engl J Med 1995, 333:1528-1533.
-
(1995)
N Engl J Med
, vol.333
, pp. 1528-1533
-
-
Danner, S.A.1
Carr, A.2
Leonard, J.M.3
-
13
-
-
0028806725
-
Clinical evaluation of the safety and efficacy of ritonavir (ABT 538), an inhibitor of HIV-1 protease
-
Markowitz M, Saag M, Powderly W, et al.: Clinical evaluation of the safety and efficacy of ritonavir (ABT 538), an inhibitor of HIV-1 protease. N Engl J Med 1995, 333:1534-1539.
-
(1995)
N Engl J Med
, vol.333
, pp. 1534-1539
-
-
Markowitz, M.1
Saag, M.2
Powderly, W.3
-
14
-
-
0028857910
-
An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR-mediated cytotoxicity without apparent effect on virus maturation and infectivity
-
Konvalinka J, Litterst MA, Welker R, et al.: An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR-mediated cytotoxicity without apparent effect on virus maturation and infectivity. J Virol 1995, 69:7180-7186.
-
(1995)
J Virol
, vol.69
, pp. 7180-7186
-
-
Konvalinka, J.1
Litterst, M.A.2
Welker, R.3
-
15
-
-
0040878605
-
Natural polymorphism of HIV-1 clade B protease gene and the implication for therapy
-
Sardinia, July [abstract 76]
-
Kozal MJ, Shah N, Yang R, et al.: Natural polymorphism of HIV-1 clade B protease gene and the implication for therapy. Fourth International Workshop on HIV Drug Resistance. Sardinia, July 1995 [abstract 76].
-
(1995)
Fourth International Workshop on HIV Drug Resistance
-
-
Kozal, M.J.1
Shah, N.2
Yang, R.3
-
16
-
-
0028988566
-
Limited sequence diversity of the HIV type 1 protease gene from clinical isolates and in vitro susceptibility to HIV protease inhibitors
-
Winslow DL, Stack S, King R, Scarnati H, Bincsik A, Otto MJ: Limited sequence diversity of the HIV type 1 protease gene from clinical isolates and in vitro susceptibility to HIV protease inhibitors. AIDS Res Hum Retroviruses 1995, 11:107-113.
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, pp. 107-113
-
-
Winslow, D.L.1
Stack, S.2
King, R.3
Scarnati, H.4
Bincsik, A.5
Otto, M.J.6
-
17
-
-
0011730295
-
Ritonavir and saquinavir: Potential for two-dimensional synergy between HIV protease inhibitors
-
San Francisco, September [abstract LB-7]
-
Norbeck D, Kumar G, Marsh K, et al.: Ritonavir and saquinavir: potential for two-dimensional synergy between HIV protease inhibitors. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, September 1995 [abstract LB-7].
-
(1995)
35th Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Norbeck, D.1
Kumar, G.2
Marsh, K.3
|