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Volumn 41, Issue 3, 1997, Pages 654-660

Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir

Author keywords

[No Author keywords available]

Indexed keywords

AMPRENAVIR; CYTOCHROME P450; INDINAVIR; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR;

EID: 0031035968     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.3.654     Document Type: Article
Times cited : (383)

References (34)
  • 1
    • 0002125830 scopus 로고    scopus 로고
    • Prolongation of life and prevention of AIDS in advanced HIV immunodeficiency with ritonavir
    • abstr. LB6a. Infectious Diseases Society of America for the Foundation of Retrovirology and Human Health, Alexandria, Va.
    • Cameron, B., M. Heath-Chiozzi, S. Kravci, R. Mills, A. Potthoff, D. Henry, The Advanced HIV Ritonavir Study Group, and J. Leonard. 1996. Prolongation of life and prevention of AIDS in advanced HIV immunodeficiency with ritonavir, abstr. LB6a. In Abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections. Infectious Diseases Society of America for the Foundation of Retrovirology and Human Health, Alexandria, Va.
    • (1996) Abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections
    • Cameron, B.1    Heath-Chiozzi, M.2    Kravci, S.3    Mills, R.4    Potthoff, A.5    Henry, D.6    Leonard, J.7
  • 2
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin, J. M. 1995. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 267:483-489.
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 7
    • 0021241325 scopus 로고
    • Overview of patient compliance with medication dosing: A literature review
    • Greenberg, R. N. 1984. Overview of patient compliance with medication dosing: a literature review. Clin. Ther. 4:592.
    • (1984) Clin. Ther. , vol.4 , pp. 592
    • Greenberg, R.N.1
  • 9
    • 0041926641 scopus 로고    scopus 로고
    • Anti HIV activity and lymphocyte surrogate marker response dynamics to ritonavir therapy in advanced HIV immunodeficiency
    • abstr. LB6b. Infectious Diseases Society of America for the Foundation of Retrovirology and Human Health, Alexandria, Va.
    • Heath-Chiozzi, M., J. Leonard, D. Henry, R. Mills, A. Potthoff, The Advanced HIV Ritonavir Study Group, and B. Cameron. 1996. Anti HIV activity and lymphocyte surrogate marker response dynamics to ritonavir therapy in advanced HIV immunodeficiency, abstr. LB6b. In Abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections. Infectious Diseases Society of America for the Foundation of Retrovirology and Human Health, Alexandria, Va.
    • (1996) Abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections
    • Heath-Chiozzi, M.1    Leonard, J.2    Henry, D.3    Mills, R.4    Potthoff, A.5    Cameron, B.6
  • 10
    • 0342473488 scopus 로고
    • Hepatic and intestinal metabolism of MK-639. An HIV protease inhibitor, in rats and human
    • Hensleigh, M., M. Chiba, and J. H. Lin. 1995. Hepatic and intestinal metabolism of MK-639. an HIV protease inhibitor, in rats and human. Pharm. Res. 12:S-374.
    • (1995) Pharm. Res. , vol.12
    • Hensleigh, M.1    Chiba, M.2    Lin, J.H.3
  • 11
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
    • Ho, D. D., A. U. Neumann, A. S. Perelson, W. Chen, J. M. Leonard, and M. Markowitz. 1995. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373:123-126.
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1    Neumann, A.U.2    Perelson, A.S.3    Chen, W.4    Leonard, J.M.5    Markowitz, M.6
  • 17
    • 0029089702 scopus 로고
    • Ketoconazole to reduce the need for cyclosporine after cardiac transplantation
    • Keogh, A., P. Spratt, C. McCosker, P. Macdonald, J. Mundy, and A. Kaan. 1995. Ketoconazole to reduce the need for cyclosporine after cardiac transplantation. N. Engl. J. Med. 333:628-633.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 628-633
    • Keogh, A.1    Spratt, P.2    McCosker, C.3    Macdonald, P.4    Mundy, J.5    Kaan, A.6
  • 18
    • 0028846226 scopus 로고
    • Crystal structure of HIV-1 protease in complex with VX-478, a potent and orally bioavailable inhibitor of the enzyme
    • Kim, E. E., C. T. Baker, M. D. Dwyer, M. A. Murcko, B. G. Rao, R. D. Tung, and M. A. Navia. 1995. Crystal structure of HIV-1 protease in complex with VX-478, a potent and orally bioavailable inhibitor of the enzyme. J. Am. Chem. Soc. 117:1181-1182.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 1181-1182
    • Kim, E.E.1    Baker, C.T.2    Dwyer, M.D.3    Murcko, M.A.4    Rao, B.G.5    Tung, R.D.6    Navia, M.A.7
  • 19
    • 0023921505 scopus 로고
    • Cyclosporine metabolism in human liver. Identification of a cytochrome P-450 III gene family as the major cyclosporine-metaholizing enzyme explains interactions of cyclosporine with other drugs
    • Kronbach, T., V. Fischer, and U. A. Meyer. 1988. Cyclosporine metabolism in human liver. Identification of a cytochrome P-450 III gene family as the major cyclosporine-metaholizing enzyme explains interactions of cyclosporine with other drugs. Clin. Pnarmacol. Ther. 43:630-635.
    • (1988) Clin. Pnarmacol. Ther. , vol.43 , pp. 630-635
    • Kronbach, T.1    Fischer, V.2    Meyer, U.A.3
  • 20
    • 0030430035 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
    • Kumar, G. N., A. D. Rodrigues, A. M. Buko, and J. F. Denissen. 1996. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J. Pharmacol. Exp. Ther. 277:423-431.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 423-431
    • Kumar, G.N.1    Rodrigues, A.D.2    Buko, A.M.3    Denissen, J.F.4
  • 22
    • 0342473486 scopus 로고    scopus 로고
    • Unpublished data
    • Marsh, K. C. Unpublished data.
    • Marsh, K.C.1
  • 24
    • 0028662025 scopus 로고
    • P450 in the rat and man: Methods of investigation, substrate specificities and relevance to cancer
    • Nedelcheva, V., and I. Gut. 1994. P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer. Xenobiotica 24:1151-1175.
    • (1994) Xenobiotica , vol.24 , pp. 1151-1175
    • Nedelcheva, V.1    Gut, I.2
  • 25
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell lifespan, and viral generation time
    • Perelson, A. S., A. U. Neumann, M. Markowitz, J. M. Leonard, and D. D. Ho. 1996. HIV-1 dynamics in vivo: virion clearance rate, infected cell lifespan, and viral generation time. Science 271:1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 28
    • 0023610798 scopus 로고
    • Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cyiochromes P-45U
    • Rodrigues, A. D., D. F. V. Lewis, C. Ioannides, and D. V. Parke. 1987. Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cyiochromes P-45U. Xenobiotica 17:1315-1327.
    • (1987) Xenobiotica , vol.17 , pp. 1315-1327
    • Rodrigues, A.D.1    Lewis, D.F.V.2    Ioannides, C.3    Parke, D.V.4
  • 29
    • 0029124814 scopus 로고
    • In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P450 3A4 (CYP3A4) and NADPH-P450 reductase
    • Rodrigues, A. D., D. Mulford, R. Lee, B. Surber, M. Kukulka, M. S. Shet, and R. W. Estabrook. 1995. In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P450 3A4 (CYP3A4) and NADPH-P450 reductase. Drug Metab. Dispos. 23:765-775.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 765-775
    • Rodrigues, A.D.1    Mulford, D.2    Lee, R.3    Surber, B.4    Kukulka, M.5    Shet, M.S.6    Estabrook, R.W.7
  • 31
    • 0029872589 scopus 로고    scopus 로고
    • A 24-week open-label phase I/II evaluation of the HIV protease inhibitor MK-639 (indinavir)
    • Stein, D. S., D. G. Fish, J. A. Bilello, S. L. Preston, G. L. Martineau, and G. L. Drusano. 1996. A 24-week open-label phase I/II evaluation of the HIV protease inhibitor MK-639 (indinavir). AIDS 10:485-492.
    • (1996) AIDS , vol.10 , pp. 485-492
    • Stein, D.S.1    Fish, D.G.2    Bilello, J.A.3    Preston, S.L.4    Martineau, G.L.5    Drusano, G.L.6
  • 33
    • 0026681640 scopus 로고
    • In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism
    • Vincent, S. H., B. V. Karanam, S. K. Painter, and S.-H. L. Chiu. 1992. In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. Arch. Biochem. Biophys. 294:454-460.
    • (1992) Arch. Biochem. Biophys. , vol.294 , pp. 454-460
    • Vincent, S.H.1    Karanam, B.V.2    Painter, S.K.3    Chiu, S.-H.L.4


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